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JP4925549B2 |
The present invention pertains, at least in part, to novel 9- substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasm...
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JP4738812B2 |
Bifunctional phenyl iso(thio)cyanate derivatives (I) are new. Also new are aniline and nitrobenzene derivative intermediates (II) and (V). Bifunctional phenyl iso(thio)cyanate derivatives of formula W=C=N-Ar-CO-NH-SO 2-A (I) are new. W :...
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JP2011140448A |
To provide a method for producing highly pure ionic vinyl monomer; to provide the ionic vinyl monomer which is good in compatibility with resins and organic solvents, is high in hydrolysis resistance, is suitably used for various kinds o...
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JP4723225B2 |
To provide a new thiocyanic ester compound with slight odor, which is useful as an antibacterial agent, a fungicide, an insecticide, a herbicide, an antifoulant, a metal chelator and the like. An alkali is activated on hydroquinone, one ...
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JP4707042B2 |
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JP4653485B2 |
Compounds of formula I: wherein Ar1 and Ar2 are optionally substituted aryl or heteroaryl, L is a bond, -CH- or -(CHRa)n-, and X is SCN, SR1, S(O)R1, (CRaRb)mSO2R1, SO2N(R2)2, SO2NHCOR1, SO2NHN(R2)2, OSO2N(R2)2, OS(O)N(R2)2, OSO2NHCOR1, ...
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JP4612219B2 |
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JP2010285414A |
To provide a vulcanizing agent to improve reversion resistance, heat-resistance and flex resistance of a rubber.A rubber composition is produced by compounding 100 pts.wt. of a sulfur-vulcanizable rubber with 0.5-20 pts.wt. of 3,6-dioxao...
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JP4597522B2 |
Preparation of 2-((4,4-difluoro- or 3,4,4-trifluoro-3-butenyl)-sulfanyl)-1,3-thiazole (I) involves reacting a 4-substituted 1,1-difluoro- or 1,1,2-trifluorobutene derivative with a thiocyanate to give a butenyl isothiocyanate, converting...
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JP2010537957A |
The invention relates to methods of using certain compounds of formula (I), (II) and (III) in the synthesis of an insecticide intermediate of formula (IV), wherein the substituents are as defined in claim 1, to processes for preparing th...
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JP4578761B2 |
The invention relates to liquid-crystalline (dihydro)phenanthrene derivatives of the formula Iin whichR, G, A<1>, Z<1>, m, L<1>, L<2>, L<3>, L<4>, L<5 >and Y are as defined in claim 1, and to liquid-crystalline media comprising at least ...
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JP4564628B2 |
The present invention provides a process for making N-alk(en)oxy(or aryloxy)carbonyl isothiocyanate derivatives by reacting a haloformate with a thiocyanate, in the presence of an aqueous solvent or an organic solvent and a catalytic amo...
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JP4543237B2 |
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JP2010180245A |
To provide binding methods and use methods of androgen receptor targeting agents (ARTA).The agents define a new subclass of selective androgen receptor modulators (SARM) compounds. Several SARM compounds are found to have an unexpected a...
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JP4422670B2 |
The present invention relates to compounds of the formula I wherein A 1 , A 2 , R 1 , R 2 , R 3 , X and n are as defined in the claims, which are valuable pharmaceutically active compounds for the therapy and prophylaxis of diseases, for...
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JP4320053B2 |
The invention relates to novel sulfonylamino(thio)carbonyl compounds of the formula (I),in whichn represents the numbers 0, 1 or 2,A represents a single bond, or oxygen or sulfur, or the grouping N-R, in which R represents hydrogen, alky...
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JP4275364B2 |
The invention relates to liquid-crystalline compounds of the formula I in which R<1>, A<1>, A<2>, Z<1>, Z<2>, a, b, L<1>, L<2 >and L<3 >are as defined in claim 1, and to liquid-crystalline media comprising at least compound of the formul...
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JP4262781B2 |
A fungicidal mixture comprisesa) a phenyl benzyl ether derivative of the formula I.a, I.b or I.c, and/or a carbamate of the formula Idwhere X is CH or N, n is 0, 1 or 2 and R is halogen, C1-C4-alkyl or C1-C4-haloalkyl, it being possible ...
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JP2009503199A |
Compositions and methods for making compositions such as RF(Rtau)nQ are provided. The RF group can include at least two -CF3 groups, the Rtau group can be a group having at least two carbons, n can be at least 1, and the Q group can incl...
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JP4212353B2 |
Disclosed is a probe for mass spectrometry of liquid samples, which may effectively ionize the sample without adding a protic solvent to the mobile phase in the ionization method in mass spectrometry of liquid samples. The probe accordin...
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JP4204069B2 |
PCT No. PCT/EP97/04166 Sec. 371 Date Jan. 29, 1999 Sec. 102(e) Date Jan. 29, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/05659 PCT Pub. Date Feb. 12, 1998Compounds of formula (3), and pharmaceutically acceptable salts and derivatives ...
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JP4163254B2 |
PCT No. PCT/EP96/05874 Sec. 371 Date Dec. 4, 1998 Sec. 102(e) Date Dec. 4, 1998 PCT Filed Dec. 19, 1996 PCT Pub. No. WO97/25309 PCT Pub. Date Jul. 17, 1997Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and ...
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JP2008137899A |
To preferentially synthesize antimicrobial trans 4-methylthio-3-butenylisothiocyanate.This method for producing 4-methylthio-3-butenylisothiocyanate comprises producing a carbon atom-halogen atom bond on a methylthio group-bound carbon a...
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JP2008137898A |
To preferentially synthesize antimicrobial trans 4-methylthio-3-butenylisothiocyanate.This method for producing 4-methylthio-3-butenylisothiocyanate comprises producing a carbon atom-halogen atom bond on a methylthio group-bound carbon a...
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JP4091983B2 |
The subject of the invention is the products of formula (I):in which R1, R2, R3, R4, R5 and G are as defined in the description, the dotted lines represent an optional second bond, as well as the addition salts with acids and bases and t...
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JP2008515978A |
One aspect of this disclosure relates generally to lipid compounds that exert diverse effects in the endocannabinoid system, such as regulating CB1 and CB2 receptor or moderating other bio-macromolecules within the endocannabinoid system...
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JP4084414B2 |
Sulphonyl-amino(thio)carbonyl substd. heterocycles (I) and their salts are new: A = single bond; O, S or NR; R = H, alkyl, alkenyl, alkynyl or cycloalkyl; Q = O or S; R1 = H, CHO, or opt. substd. alkyl, alkenyl, alkynyl, alkylcarbonyl, a...
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JP2008512644A |
The present invention relates to a compound for N-terminal substitution of polypeptides which is used in sequencing and quantifying amino acids and a method for sequencing and quantifying an amino acid sequence using the same. The method...
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JP4078439B2 |
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JP4053602B2 |
A process for the preparation of a thiocyanate of Formula II Rf-Am-(CH2)n-SCN IIwherein Rf is a C2-C20 perfluoroalkyl radical, or a C5-C38 perfluoroalkyl radical having at least one ether oxygen atom; n is 1 to 3; m is 0 or 1; A is O, S,...
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JP2008001622A |
To provide an inclusion compound capable of stabilizing and controlling the release over a long period by including allyl isothiocyanate in high content, and a method for producing the compound.The inclusion compound comprises diphenic a...
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JP2007530470A |
The instant invention relates to mesogenic compounds with mesogenic group and one or more bulky end groups which each contain at least two ring elements, where two of these ring elements are linked to a centre atom or to a centre group b...
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JP3982949B2 |
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JP3919489B2 |
To provide a method for stably producing isothiocyanates free from any pungency component from naturally occurring cruciferous plant(s) such as Wasabi, horseradish and watercress (scientific name: Roripa nasturtium- aquaticum) at high yi...
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JP3912812B2 |
To obtain an aqueous solution not evolving hydrogen disulfide during preservation in an aqueous solution containing a metal salt of dithiocarbamic acid as a main component. A compound containing at least one primary amino group (e.g. die...
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JP3899210B2 |
To obtain an activity-inducing substance which can activate or increase glutathione-S-transferase(GST) as one of the second phase foreign matter- metabolizing enzymes in biological foreign matter metabolism, and exhibits a strong activit...
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JP3891637B2 |
To safely produce the subject compound useful as a synthetic raw material for pharmaceuticals, agrochemicals and chemicals or an antibacterial agent or antifungal agent in high yield by reacting a specific clithiocarbamic acid or its sal...
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JP2007008921A |
To predominantly synthesize trans 4-methylthio-3-butenyl isothiocyanate having an antibacterial action.To predominantly produce trans 4-methylthio-3-butenyl isothiocyanate useful as a natural substance having antibacterial activity, firs...
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JP3844793B2 |
PURPOSE: To obtain a new compound useful for protection of plants and effective in controlling fungous diseases of crops. CONSTITUTION: This compound is that of formula I (W is O, S or S=O; M is O, S or, if the case may be, halogenated C...
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JP3836888B2 |
PURPOSE: To obtain a composite material containing a non-polymeric bonded platform molecule and useful for the treatment of autoimmune diseases such as systemic lupus erythematosus. CONSTITUTION: This composite material contains a non-po...
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JP3833698B2 |
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JP3786579B2 |
The present invention relates to compounds of the formula I wherein A 1 , A 2 , R 1 , R 2 , R 3 , X and n are as defined in the claims, which are valuable pharmaceutically active compounds for the therapy and prophylaxis of diseases, for...
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JP2006124345A |
To provide poly[2-thiocyanatoethyl (meth)acrylate] that is different from conventional thiocyanate ester compounds, has no smell and is useful as a antibacterial agent, an antifungal agent, an insecticidal agent, a herbicidal agent, a st...
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JP2006124304A |
To provide a novel thiocyanate compound that has reduced smell and is useful as a antibacterial agent, an antifungal agent, an insecticidal agent, a herbicidal agent, a stainproofing agent, a metal chelator and the like.2-Halogenoethyl (...
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JP3757236B2 |
Novel farnesyl derivatives which are inhibitors of the prenylated protein methyltransferase enzyme, and useful as anti-cancer drugs, have the following formula: wherein R1represents farnesyl, geranyl or geranyl-geranyl; Z represents C-R6...
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JP2006508154A |
Cyclobutane compounds (I) are new. Cyclobutane compounds of formula (I) are new: R1, R2 = H, F, Cl, Br, I, optionally chiral 1-15C alkyl or alkoxy optionally substituted by halo and having CH2 groups replaced by -O-, -S-, -CO-, -COO-, -O...
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JP3749604B2 |
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JP3742430B2 |
PCT No. PCT/EP94/02546 Sec. 371 Date Apr. 5, 1995 Sec. 102(e) Date Apr. 5, 1995 PCT Filed Aug. 1, 1994 PCT Pub. No. WO95/04790 PCT Pub. Date Feb. 16, 19952-Fluorocyclohexene derivatives of formula I are as defined herein, and their use a...
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JP3695782B2 |
PURPOSE: To obtain a new compound having strong repellent activity and antibiological activity against underwater noxious organisms and low toxicity, persistence, etc., to human body and not exercising adverse influence on ecosystem and ...
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JP3688785B2 |
To obtain an isothiocyanate compound having functional groups such as a hydroxyl group in the same molecule and useful as a raw material for synthesizing medicines, agricultural chemicals, etc., and as an antibacterial agent and an antif...
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