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WO/2022/129618A1 |
A method for preparing at least one watercress extract, which method comprises: (a) macerating watercress to form an aqueous watercress intermediate; (b) heating at least part of the aqueous watercress intermediate to coagulate at least ...
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WO/2022/047212A1 |
This invention relates generally to neurodegenerative diseases and conditions (e.g., Alzheimer's disease) characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biolo...
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WO/2022/037675A1 |
A preparation method for sulforaphane and a use thereof, which relates to the technical field of biology, the method comprising: taking broccoli seeds or broccoli sprouts, freeze-drying same and then grinding to obtain a first component;...
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WO/2022/030343A1 |
The present invention provides a compound that has a high refractive index anisotropy (Δn), the effect of increasing the phase transition temperature of a liquid crystal phase, and high solubility, and exhibits high dielectric anisotrop...
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WO/2021/129747A1 |
Disclosed in the present invention are a magnolol and sulforaphane conjugate, and a preparation method therefor and use thereof. The magnolol and sulforaphane conjugate comprises C25H29NO2S2(CT-1), C25H29NO4S2(CT-2), and C25H29NO3S2(CT-3...
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WO/2020/238559A1 |
Disclosed are a de-C2-symmetric diphenylamine-type chiral bisoxazoline ligand as shown in formula 3, a synthesis method therefor and the use thereof in an asymmetric catalytic reaction. The C2-symmetry of the ligand is removed by introdu...
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WO/2019/217977A1 |
Disclosed herein are compounds represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. Values for the variables in Structural Formula I are described herein. The compounds can be used to modulate (e.g, inhib...
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WO/2019/193483A1 |
The present disclosure relates to a new catalytic process for the production of methanol from carbon dioxide, comprising: (1) the conversion of carbon dioxide and hydrogen to formic acid or formate salts; (2) converting the formic acid o...
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WO/2019/163594A1 |
[Problem] The present invention addresses the problem of efficiently isomerizing lycopene, more specifically, shortening a step for isomerizing lycopene. [Solution] As the results of intensive studies, the present inventor found that lyc...
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WO/2019/036050A1 |
The disclosure relates to compositions containing allyl isothiocyanate and methods of use thereof for stimulating tearing in a subject to treat dry eye.
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WO/2018/185523A1 |
The invention relates to defence spray compositions of non-lethal chemical weapons for riot, crowd control or self-defence with mild incapacitating effect, low degree of volatility, and not flammable. A spray composition for temporarily ...
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WO/2018/153381A9 |
The present invention provides a high-purity isothiocyanate compound preparation method for industrial production. Specifically, in the method, organic amine and CS2 are used as raw materials to prepare the thiocarbamate, and then desulf...
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WO/2018/058246A1 |
The present invention discloses a novel therapeutic axis NTPDase8 enzyme, Ρ2Υ6 and/or P2Y2 receptors, and provides methods, enzymes and/or antagonists for remedying inflammatory bowel diseases.
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WO/2017/208914A1 |
The present invention provides: a liquid crystal panel which is able to be driven at a low voltage, while achieving a wide color gamut, and which is suppressed in the production of residual DC due to ultraviolet light that is contained i...
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WO/2017/106007A1 |
A method of treating sour water from industrial processes such as coal gasification. The method includes injecting a polysulfide into a sour water stream to convert cyanide to thiocyanate, thereby reducing the corrosiveness and toxicity ...
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WO/2016/194813A1 |
The purpose of the present invention is to provide a new process for producing an enzalutamide crystal form which is reduced in the contents of 2-propanol and B-form crystals, the process including obtaining wet crystals of enzalutamide ...
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WO/2016/168059A1 |
This disclosure relates to the field of moiecuies having pesticida i utility against pests in Phyla Arthropoda, Moliusca, and hJematoda, processes to produce such moiecuies, intermediates used In such processes, pesticidai compositions c...
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WO/2016/168058A1 |
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...
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WO/2016/143634A1 |
Provided is a bimesogenic compound which exhibits high solubility in other bimesogenic compounds and substances used in conventional liquid crystal display elements, such as liquid crystalline compounds, liquid crystal compositions, chir...
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WO/2016/127873A1 |
The present invention provides an isothiocyanate compound and an application thereof. The compound is an aryl substituted isothiocyanate compound that has a structure in the general formula I. The isothiocyanate compound in the present i...
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WO/2016/071863A1 |
The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts thereof: (I) wherein Ri is selected from an SCN- group or is an RCONH- group; in particular, where Ri = RCONH, R is selected from an aromatic...
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WO/2016/014522A1 |
Disclosed are small molecule inhibitors of deubiquitinating enzymes (DUBs), and methods of using them. Certain compounds are selective for particular ubiquitin-specific proteases (USPs).
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WO/2014/167560A1 |
This invention provides pure methylene bis(thiocyanate) in an ecor industrial process. The product is practically free of insolubles (<0.1%) after prolonged storage.
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WO/2014/154117A1 |
An isothiocyanate having the following structural formula (I). The isothiocyanate synthesis processing technique is as follows: obtained by using conventional organic bases, carbon disulfide, and acetyl chloride to react in a low tempera...
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WO/2014/141082A1 |
The invention relates to a novel agent in the form of rhodanine derivatives, which has prophylactic, antiproliferative and antimetastatic activity. Said agent can find use in medicine and pharmacology for the prophylaxis and/or treatment...
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WO/2014/136690A1 |
The present invention pertains to: a production method for an isothiocyanate using an organic primary amine and thiourea as starting materials; a composition for transporting and storing a N-substituted O-substituted thiocarbamate, said ...
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WO/2014/058996A1 |
Provided herein are processes for the preparation of alkoxycarbonyl isothiocyanates from alkyl chloroformates and thiocyanates in toluene by controlling the amounts of water and catalyst.
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WO/2013/179057A1 |
The present invention relates to a method of synthesising sulforaphane by reacting a compound of formula (A) with an oxidizing agent in an aqueous solvent and in the presence of a catalyst. The invention further provides a method of synt...
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WO/2013/179056A1 |
The present invention relates to methods of isolating and purifying sulforaphane. More specifically, the present invention relates to methods of isolating and purifying sulforaphane from natural sources. The present invention also relate...
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WO/2013/157229A1 |
[Problem] The present invention provides an alkylphenylsulphide derivative having excellent pest control effect or a salt thereof, a pest control agent containing the same as an active component and a production intermediate thereof. [So...
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WO/2013/132124A1 |
The present invention relates to a new series of compounds having general formula (I) and the optical isomer or enantiomer forms thereof, which belong to the family of sulforaphane derivatives. The invention also relates to the productio...
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WO/2013/067646A1 |
The present application provides processes and intermediates useful in the production of β- aminocarbonyl- or β-aminothiocarbonyl-containing compounds. Provided herein is a process for synthesizing β-aminocarbonyl- or β-aminothiocarb...
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WO/2013/041204A1 |
The invention relates to novel isocyanate and isothiocyanate compounds, pharmaceutical compositions comprising same, and the use thereof for the treatment of cancer in humans and animals. Compared with previously known isocyanate and iso...
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WO/2013/031603A1 |
Provided are: a liquid-crystal compound that can combine characteristics such as chemical stability, excellent compatibility with other liquid-crystal materials or non-liquid-crystal materials, fast response, low viscosity, a wide liquid...
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WO/2012/158008A1 |
Sulforaphane is an isothiocyanate having anti-microbial and anti-carcinogenic properties, found in a broad range of vegetables of the Brassica oleracea genus, of which broccoli and cabbage are considered to be the most important types. T...
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WO/2012/146569A1 |
The invention relates to a method for producing 2-chloroallyl isothiocyanate from 2,3-dichloro-1-propene, wherein the 2,3-dichloro-1-propene is reacted with a thiocyanate in the presence of a phase-transfer catalyst, without diluent or i...
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WO/2012/073314A1 |
The purpose of the invention is to provide a novel production method for producing a corresponding isothiocyanate compound having a carboxyl group at high purity in one step by a reaction of an amino compound having a carboxyl group, thi...
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WO/2012/010644A1 |
Process for the synthesis of an isothiocyanate of general formula (I) SCN‑R1-R4-R2 in which R1 and R2 represent, independently of one another, an alkyl, aryl or alkylaryl group, R4 represents a carbonyl, sulphinyl or sulphonyl group or...
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WO/2011/073143A1 |
Substituted cyanobutyrates of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts...
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WO/2010/140902A1 |
The invention provides the use of isothiocyanate and isoselenocyanate compounds for treating diseases and conditions mediated by MIF.
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WO/2010/140271A1 |
Disclosed is a substance which can potentiate the power of α brain waves produced from the cerebrum of a human to exhibit a relaxing activity, an concentration-enhancing activity and an anti-stress activity. Specifically disclosed is a ...
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WO/2010/125414A1 |
The subject of the present invention is a novel process for the preparation of the [4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-thiazolo-2-y
l]-[2-cyclopropyl-1-(3-fluoro-4-methylphenyl)-ethyl]-amine of formula (I) and the new interme...
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WO/2009/145816A2 |
A first aspect of the invention is a compound (sometimes also referred to herein as an "active agent" or "active compound") of Formula (I) or ( Ia): or a pharmaceutically acceptable salt or prodrug thereof. Compositions thereof and metho...
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WO/2009/107796A1 |
Disclosed is a novel method for producing a corresponding isothiocyanate compound having a carboxyl group from an amino compound having a carboxyl group. Specifically disclosed is a method for producing an isothiocyanate compound having ...
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WO/2009/073592A2 |
The present invention provides fluoroalkyl amines represented by the formula R1-Q-S(O)x-C(H),(CH3)r(CH2)z+(1-1)-NHR and fluoroalkyl isocyanates and isothiocyanates represented by the formula RrQ-S(O)x-C(H)l(CH3)r(CH2)Z+(1-1)-N=C=X1, wher...
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WO/2009/030457A1 |
The invention relates to methods of using certain compounds of formula (I), (II) and (III) in the synthesis of an insecticide intermediate of formula (IV), wherein the substituents are as defined in claim 1, to processes for preparing th...
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WO/2008/009127A1 |
The present invention relates to derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) having improved anti-inflammatory properties useful in the treatment of inflammation, pain and fever. More particularly, NSAIDs are derivatize...
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WO/2008/008954A2 |
The present invention provides glucosinolate and isothiocyante compounds and related methods for synthesizing these compounds and analogs. In certain embodiments, these glucosinolate and isothiocyanate compounds are useful and chemopreve...
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WO/2007/122488A2 |
The present invention provides a process for [18F]-fluorination of biomolecules containing a primary amino group such as proteins and peptides and in particular of peptides. The invention further provides reagents for this process, in pa...
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WO/2007/082996A1 |
This invention concerns novel neutral labeling reactants. The novel reactants are deri- vatives of diethylenetriaminepentaacetic acid (DTPA) diamides, wherein a suitable group is linked to the molecule allowing introduction of the said n...
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