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WO/2002/062752A1 |
A process for producing a cyclic sulfone compound represented by the formula (2) (2) or the formula (4) (4) (wherein the three broken lines indicate that one of the three bonds is a double bond; Ar represents optionally substituted aryl;...
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WO/2002/060865A1 |
A method of isolating Zeaxanthin, Cryptoxanthin, and other carotenoids in a high purity from the Byadagi and Chappatta chili varieties is disclosed. The method may also be used to obtain a mixture of Zeaxanthin, Cryptoxanthin and other c...
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WO/2002/055540A1 |
The present invention relates to novel retinol derivatives, the methods of preparation and the uses thereof. According to the present invention, retinol derivatives comprise carboester linkage between di-, tri-, polypeptide having functi...
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WO/2002/053530A1 |
The invention concerns a method for concentrating and stabilising carotene from vegetables or fruits, whereby in particular the fruits and vegetables are ground. The invention is characterised in that it consists in: blanching the result...
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WO/2002/050022A1 |
A process for the production of a carotenoid which comprises reacting a retinal with a titanium (IV) compound in the presence of zinc and an inert solvent, in particular a process for the production of beta-carotene from retinal.
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WO/2002/046131A1 |
The present invention relates to substituted cyclohexenes, to their use as well as to their preparation method. These compounds have powerful long lasting natural fruity grapefruit notes with minty and fresh green tonalities.
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WO/2002/042247A1 |
Disclosed are retiferol derivatives of formula (I): wherein X is > C=CH¿2? or -CH¿2?-; Y and Z are independently of each other hydrogen, fluorine or hydroxy; A is -O(CH¿2?)¿3?-, -(CH¿2?)¿2?-(1,2-C¿6?H¿4?)-, -CH=CH-(1,2-C¿6?H¿4?...
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WO/2002/034700A1 |
The method of the invention uses raw corn, or a corn by-product as a source. The source is mixed with an alcohol (2) to produce an alcohol-corn slurry. Centrifugation or filtration (3) produces a clear filtrate from the alcohol-corn slur...
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WO/2002/034710A2 |
The invention concerns compounds of formula (1) wherein in particular G represents the -N(CH¿3?)¿2?-, -N(C¿2?H¿5?)¿2?-group or N-pyrrolidine; n is an integer equal to 1 or 2; R¿1?, R¿2? and R¿3?, independently of one another, rep...
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WO/2002/026727A2 |
Novel compounds having the Formulas 1 through 8, wherein the symbols have the meaning defined in the specification, and certain previously known compounds have been discovered to act as inhibitors of the cytochrome P450RAI (retinoic acid...
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WO/2002/012183A1 |
The present invention relates to a process for extracting astaxanthin pigment from the blue-green algae comprising the steps of i) cultivating the blue-green algae, ii) treating blue-green algae culture suspension with microwave to destr...
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WO/2002/010128A2 |
Disclosed are processes for conversion of (3R,3'R,6'R)-lutein to (3R,6'R)-α-cryptoxanthin,(3R)-β-cryptoxanthin, anhydroluteins I, II, and III (dehydration products of lutein), and a method for separating and purifying the individual ca...
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WO/2002/008182A1 |
The invention relates to a method for the production of a water-dispersible formulation containing carotenoids. The $g(b)-carotene was dissolved in n-isobutyl acetate and the hot solvent phase was dispersed in a modified water starch sol...
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WO/2002/003912A2 |
Novel C-4 substituted all-trans retinoic acid analogs are synthesized and used to treat various cancers and dermatological diseases and conditions. These novel C-4 substituted all-trans retinoic acid analogs inhibit all-trans retinoic ac...
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WO/2002/004415A2 |
Disclosed is a process for purification of a mixture of carotenoids from palm oil concentrate to produce a crystalline mixture of a $g(a)-carotene, $g(b)-carotene, $g(g)-carotene, and $g(e),$g(e)-carotene as well as a product enriched in...
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WO/2001/094279A2 |
The present invention provides an industrial scale process for obtaining lutein and zeaxanthin concentrates of high purity from saponified marigold extracts that may have high levels of chlorophyll.
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WO/2001/083437A1 |
The present invention relates to a process for extracting astaxanthin pigment from the yeast cells of Phaffia rhodozyma comprising the steps of i) cultivating the yeast, ii) treating yeast culture suspension with microwave to destroy the...
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WO/2001/083438A2 |
New RAR selective retinoid agonists of formula (I) wherein the symbols are as defined in the specification, and pharmaceutically active salts of carboxylic acids of formula (I), further the invention relates to the use of such retinoic a...
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WO/2001/081301A2 |
The present invention provides a method for preparing astaxanthin from zeaxanthin. Specifically, the present invention provides a method for said conversion using a halogenating agent with the salt of chloric or bromic acid in an inert s...
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WO/2001/077230A2 |
The invention provides a method for recovery of compounds by adsorption to fish scales. The method can be used for natural and synthetic compounds such as various natural pigments including astaxanthin in an esterified or not and synthet...
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WO/2001/072296A1 |
A method of inhibiting the expression of inflammatory cytokines and chemokines in an animal or man, is disclosed. The method comprises administration to said animal or man of at least one type of xanthophyll, e.g. astaxanthin, in an amou...
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WO/2001/072667A2 |
The invention concerns a method for chemoselective oxidation of an organic compound comprising several potentially oxidizable groups whereof at least one is a nitrogen group. Said method is characterised in that it consists in using at l...
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WO/2001/066077A1 |
The invention relates to the use of 4-oxoretinol and 4-oxoretinyl derivatives of general formula (I), wherein R has the following meaning: hydrogen, C¿1?-C¿12?-alkyl, C¿1?-C¿20?-acyl, C¿1?-C¿12?-alkoxycarbonyl, an amino acid radica...
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WO/2001/064610A1 |
An integrated process for producing alkylbenzenes, sulfonated alkylbenzenes and/or alkylcyclohexanes from syngas is disclosed. The process involves subjecting syngas to Fischer-Tropsch conditions. Fractions rich in C¿6-8? and C¿18-26? ...
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WO/2001/055100A1 |
The present invention relates to a crystalline carotenoid compound, such as $g(b)-carotene, with a purity of at least 95 % and with substantially no solvent enclosed in the crystal lattice. The present invention further describes a proce...
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WO/2001/055098A1 |
The present invention is directed to a compound having the structure (I): and acceptable salts, polypeptides, and pro-forms thereof, wherein R is selected from the group consisting of: (a) substituted glycerols; wherein n is an integer f...
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WO/2001/051162A1 |
A method and apparatus (101) for the recovery of fat soluble compounds, such as beta carotene, is described. In one embodiment of the invention a solution (102) containing a fat soluble compound is passed through a fluidised bed (104) of...
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WO/2001/046133A1 |
A general process for the extraction of carotenoids from a carotenoid source such as a biomass, which may be various biomasses including the yeast Phaffia rhodozyma, comprises treating the carotenoid source at an elevated temperature wit...
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WO/2001/034606A1 |
Isoindolin-1-one and Isoindoline-1, 3-dione substituted in the 2-position with an $g(a)-(3, 4-disubstituted phenyl)alkyl group and in the 4- and/or 5-position with a nitrogen-containing group are inhibitors of, and thus useful in the tre...
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WO/2001/034092A2 |
The invention relates to the development of a novel artificial sea water medium comprising conventional salts as NaCl and MgSO¿4? with the addition of KCl in the proportion defined in the specification to generate biomass of higher caro...
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WO/2001/034546A2 |
Omega chain modified 15-HETE derivatives and methods of their use for treating dry eye are disclosed.
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WO/2001/028966A2 |
An industrial process for obtaining highly pure xantophyll concentrates from vegetable extracts involving the following steps: refining the vegetable extracts by means of treatment with a diluted alkali, followed by a treatment with a di...
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WO/2001/009089A1 |
The present invention relates to a process for the preparation of 13-cis isomer of Vitamin A acid, commonly known as isotretinoin, in a single step.
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WO/2000/068190A2 |
Compounds of Formula (1) and Formula (2) where the symbols have the meaning defined in the specification, have retinoid, retinoid antagonist or retinoid negative hormone like biological activity.
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WO/2000/068191A1 |
Compounds of Formula (1), Formula (2), Formula (3) and Formula (4) wherein the symbols have the meaning assigned to them in the disclosure have retinoid-like biological activity.
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WO/2000/061524A1 |
The invention relates to a method for oxidizing organic substrates using ?1¿O¿2? in which hydrophobic organic substrates that react with ?1¿O¿2 are added to an organic solvent in the presence of a heterogeneous or homogeneous catalys...
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WO/2000/059860A1 |
Dihalogenated derivatives represented by general formula (2); a process for the preparation of the derivatives; and a process for the preparation of vitamin A by the use of the derivative, wherein X is halogeno; and R?2¿ is a hydroxyl-p...
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WO/2000/053563A1 |
Ligands of nuclear receptors PPAR's (peroxisome proliferator-activated receptors) which are compounds selected from the group consisting of ascofuranone; and ascofuranone homologs and ascochlorin homologs having at least an orcyl aldehyd...
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WO/2000/048991A1 |
The present invention provides luminescent lanthanide metal chelates comprising a metal ion of the lanthanide series and a complexing agent comprising at least one salicylamidyl moiety. Also provided are probes incorporating the salicyla...
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WO/2000/044720A1 |
The invention provides a method to synthesizing ethyleneimine dimer. This method of synthesis provides several advantages over previous methods: (1) the starting compounds are all relatively inexpensive; (2) the yield of product is great...
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WO/2000/044718A1 |
The invention relates to carotenoid degradation products that can be obtained from an extract of $i(Skeletonema costatum). The invention also relates to the use thereof in order to obtain a medicament that has an anti-tumoral effect.
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WO/2000/039133A1 |
The present invention describes novel C-15 allenic phosphonate reagent compositions of formula (8) wherein R and R' = C¿1? - C¿4? alkyl groups or R, R' = (CH¿2?)¿n? (n = 2 or 3). The invention also describes novel C-15 allylic phosph...
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WO/2000/035867A1 |
It has been newly found out that ascochlorin, which is a publicly known fat-soluble antibiotic, and its homologs serve as a ligand of retinoid X receptor and react $i(in vivo) with the amino group of serum protein to form Schiff bases wi...
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WO/2000/027810A1 |
The present invention provides valuable intermediates which can be used in the synthesis of a compound having polyene chain structure, processes for preparing the same, and a process for preparing $g(b)-carotene by using said intermediat...
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WO/2000/024712A1 |
Compounds represented by general formula (1), wherein R¿01? and R¿02? are each independently hydrogen or a hydroxyl-protecting group; and Z is a group represented by general formula (1-1), (1-2), (1-3), (1-4) or (1-5). These compounds ...
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WO/2000/024713A1 |
A process for easily preparing retinol useful in the fields of drugs, feed additives and food additives, by reacting a halogenated sulfone derivative represented by general formula (1): wherein Ar is optionally substituted aryl; and X is...
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WO1999058611B1 |
A process for extracting carotenes from carotene-containing materials, in particular from fats and oils of biological origin, which provides for extraction of said carotene-containing material with an extractant comprising at least one m...
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WO/2000/007458A1 |
This invention relates to the $i(in situ) process for converting non free form xanthophylls to free xanthophylls in the biological material of the plant. The method more particularly relates to a method that would liberate xanthophylls b...
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WO/2000/002928A1 |
The invention relates to a method for the stereoselective production of grignard compounds of formula (I), to polymer-bonded compounds of formula (Ia), to the use of the method for producing libraries of substances and to the use of the ...
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WO/2000/002854A1 |
The invention concerns a novel method for preparing vitamin A from ethynyl-retro-$g(a)-ionol using an allene acetate as intermediate.
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