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WO/2017/170934A1 |
The present invention pertains to an acetylacetone derivative which is useful in trapping metal elements by complex formation, and a simple and highly versatile synthesis method therefor. More specifically, the present invention pertains...
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WO/2017/162511A1 |
The present invention relates to a process for the purification of curcumin comprising provision of a curcuminoid composition, contacting said curcuminoid composition with basic amino acid or amino acid ester in order to form an amino ac...
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WO/2017/165822A1 |
A compound, or a stereoisomer, pharmaceutically acceptable salt, or ester thereof, according to formula (III) or according to Table A, a pharmaceutical composition comprising said compound and at least one pharmaceutically acceptable add...
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WO/2017/165170A1 |
In some aspects, the present disclosure provides compounds of the formula: wherein the variables are as defined herein. In some embodiments, the present disclosure provides macrocylic compounds and oligomers thereof of formula I. As desc...
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WO/2017/157932A1 |
The invention relates to a new and efficient process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or ...
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WO/2017/155120A1 |
The present invention addresses the problem of providing a long life catalyst which can be produced simply and inexpensively, which exhibits high activity, and in which metal leakage is suppressed. Provided is a catalyst according to sev...
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WO/2017/148357A1 |
The present invention relates to a sacubitril intermediate and a preparation method thereof. The sacubitril intermediate can be prepared by subjecting a compound to a deprotection reaction. The intermediate can be used as a raw material ...
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WO/2017/146444A1 |
The present invention relates to a method for preparing (meth)acrylate group-containing benzophenone for an optical adhesive, comprising the steps of: preparing a raw material composition by mixing a benzophenone-based compound containin...
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WO/2017/147212A1 |
This disclosure provides compositions of metal-binding fluorinated compounds and associated methods for producing cellular labels for tracking cells by magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomogra...
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WO/2017/143106A1 |
Provided herein are compositions and methods of treating liver cancer by novel anticancer agents.
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WO/2017/141138A1 |
Methods of preparing syngas are provided. Blend gas obtained from methane steam reforming can be reacted with CO2 in the presence of a catalyst to provide syngas with a composition ideal for oxo-synthesis.
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WO/2017/140607A1 |
A method of making spirogalbanone comprising the steps of: (a) subjecting ethynylspirodecanol to a Rupe rearrangement to give a compound of the formula I; (b) converting the compound of (a) to a C1-C4 alkyl acetal; (c) subjecting the ace...
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WO/2017/133675A1 |
The present invention relates to a method for preparing a high-purity cyclohexenone long-chain alcohol represented by formula I. The compound represented by formula I is prepared by using metal-mediated Barbier reaction. The method of th...
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WO/2017/130156A1 |
The invention relates to compounds of Formula (I), (II), (III) or (IV), salts thereof, pharmaceutical compositions thereof, as well as methods of treating, curing or preventing HIV in subjects.
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WO/2017/130109A1 |
Disclosed is an improved method of synthesis for Treprostinil comprising condensation reaction of compound (4) with a hydroxyl-protected alkynol (5) to give the condensation product, compound (6). Subjecting compound (6) to oxidation, re...
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WO/2017/125087A1 |
The present invention relates to a manufacturing method for a high-purity cyclohexenone long-chain alcohol compound represented by formula (I). The manufacturing method for the compound represented by formula (I) adopts a metal-induced B...
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WO/2017/125964A1 |
The purpose of the present invention is to provide a method for producing a ketene derivative wherein the consumption of a phosphorus compound can be reduced and the discharge of the phosphorus compound into the environment can be also r...
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WO/2017/119515A1 |
An object of the present invention is to provide a novel ascochlorin derivative which activates adenosine monophosphate-activated protein kinase (AMPK), and is useful in the treatment or prevention of diseases or conditions that involve ...
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WO/2017/116253A1 |
The present invention relates to the process for production of ketones from secondary alcohols by the use of a hybrid material, formed by the dichlorohydrotris(pyrazol-1-y1)methane iron (II) complex covalently bound to multi-walled carbo...
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WO/2017/114058A1 |
The present invention discloses a method for preparing an optically active carbonyl compound, comprising the following steps: subjecting an α,β-unsaturated aldehyde or an α,β-unsaturated ketone to an asymmetric hydrogenation catalyze...
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WO/2017/111357A1 |
Disclosed is a method for recovering phenol and acetone from a bisphenol-A residue decomposition reaction product, the method being capable of improving economic feasibility and efficiency by utilizing a phenol/acetone purification proce...
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WO/2017/106930A1 |
The present invention describes non-cyclic enaminoketone compounds and their applications relating to absorption electromagnetic energy, in particular UV radiation.
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WO/2017/112702A1 |
Methods of preparing a fenfluramine active pharmaceutical ingredient are provided. Aspects of the method include (a) hydrolyzing a 2-(3-(trifluoromethyl)phenyl)acetonitrile composition to produce a 2-(3-(trifluoromethyl)phenyl)acetic aci...
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WO/2017/108946A1 |
Meta and para alkenyl phenols are reacted with hydroxyl benzophenone to produce compounds of the genera formula or which are used as curatives for polymaleimide resins.
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WO/2017/106974A1 |
Two isoforms of thyroid receptor alpha (THRα1 and THRα2) have been found to be associated with the growth of cancer. Use of inhibitors of THRα1 (Formula I) and/or agonists of THRα2 (Formula II) in the treatment of such cancers is dis...
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WO/2017/104798A1 |
The objective of a first invention of the present invention is to provide a method that makes it possible to efficiently produce an oxidation reaction product of a hydrocarbon or derivative thereof using the hydrocarbon or derivative the...
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WO/2017/104589A1 |
Provided is a method for producing a perfluoroalkylated compound at low cost, safely and with high efficiency. A method for producing a perfluoroalkylated compound, comprising reacting a bis(perfluoroalkanoyl)peroxide with a compound tha...
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WO/2017/101553A1 |
Disclosed are a fluorene multifunctional photoinitiator as represented by general formula (I), a photosensitive resin composition containing same, and the preparation thereof and uses of the two. The compound has the advantages of simple...
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WO/2017/101791A1 |
Disclosed are a compound and a use thereof in preparing a drug, and in particular, provided in the present invention are: the compound as shown in formula (I) or a stereoisomer, a geometric isomer, a tautomer, a racemate, a nitroxide, a ...
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WO/2017/100985A1 |
Disclosed is a method for preparing 2,2-dihalo-1,3-dicarbonyl derivatives. The method is applicable in a broad range of 1,3-dicarbonyl derivatives, which have various types of readily available raw materials. The method is utilized to pr...
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WO/2017/098048A1 |
The present invention is directed to a process for the manufacture of 6,10, 14- trimethylpentadecan-2-one ("C18-ketone") comprising the step of hydrogenating a mixture of (5E,9E)-farnesylacetone and (5Z,9E)- farnesylacetone with hydrogen...
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WO/2017/098049A1 |
The present invention is directed to a process for the manufacture of 6,10,14- trimethylpentadecan-2-one ("C18-ketone") comprising the step of hydrogenating a mixture of (5E, 9E)-farnesylacetone and (5Z, 9E)- farnesylacetone with hydroge...
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WO/2017/099072A1 |
Provided is a method in which a hydroperoxide is decomposed quickly and with high selectivity using an alkaline aqueous solution and the alkali is recovered and recycled, thereby producing the corresponding target ketone and/or alcohol a...
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WO/2017/099210A1 |
The present invention addresses the problem of providing a novel nuclear factor κB (NF-κB) inhibitor. An NF-κB inhibitor that comprises, as an active ingredient, a naphthoquinone compound represented by general formula (1) or a pharma...
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WO/2017/097938A1 |
A compound of formula (I), in which, independently, R1 is selected from H and methyl; R2 is selected from H, and methyl; R3 is selected from H, methyl and ethyl; R4 is selected from H, methyl and ethyl; or R3 and R4 together form a ring ...
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WO/2016/144909A9 |
Provided herein are redox flow (e.g., rechargeable) batteries having a first aqueous electrolyte including a first type of redox active material (e.g., a quinone or alloxazine) and a second aqueous electrolyte including a second type of ...
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WO/2017/098050A1 |
The present invention is directed to a process for the manufacture of 6,10,14-trimethylpentadecan-2-one ("C18-ketone") comprising the step of hydrogenating a mixture of (3E,5E,9E)-3,4-dehydrofarnesylacetone and (3Z,5E,9E)-3,4-dehydrofarn...
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WO/2017/095237A1 |
The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to prot...
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WO/2017/093749A1 |
There is described a method of preparing a compound of formula I, and optical isomers thereof: in which R1 is hydrogen or a protecting group; said method comprising oxidising verbenone and optical isomers thereof.
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WO/2017/083967A1 |
The present invention provides purified compounds extracted from seaweeds having the formula (I): wherein R1 and R2 is each independently H or a fatty acid and their use for inhibiting the growth of cancer cells.
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WO/2017/087539A1 |
The use of long-chain alkenones to impart desired characteristics in personal care compositions for topical applications is described. The preparation of mixtures long-chain alkenones and synthetic derivatives thereof is presented. Examp...
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WO/2017/076264A1 |
The present invention relates to a class of compounds as shown in general formula I or pharmaceutically acceptable salts thereof, a preparation method therefor, application thereof as a small molecule tool that functions as a GPR84 agoni...
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WO/2017/072719A1 |
The present invention relates to a new process for the synthesis of 17β-hydroxy- des-A-androst-9,10-en-5-one, the compound of the following formula (1), which can be used as an intermediate in the synthesis of retroprogesterones.
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WO/2017/071871A1 |
The invention relates to the production of specific ketones of formulae (I) and (VI), as defined herein, which act as photolabile pro-fragrances.
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WO/2017/070651A1 |
Disclosed is a process for preparing (Z)-endoxifen, comprising (i) recrystallizing an input crystalline solid comprising a mixture of (Z)-endoxifen (1) and (E)-endoxifen (2) from a first solvent to provide a first crystalline solid and a...
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WO/2017/067634A1 |
The invention relates to the use of hydrophilic compounds of formula (I) as photopolymerization initiators of polymerizable substance mixtures, which contain unsaturated compounds, or to the photochemical cross-linking of linear polymers...
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WO/2017/065219A1 |
A phenacene compound represented by general formula (1). In general formula (1), R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 each independently represent a hydrogen atom or a group represented by general formula (2), and any one of R3, R...
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WO/2017/066668A1 |
Compositions are disclosed having a cytotoxic and/or vascular disrupting agent (VDA) payload attached to a linker. The linker can be a cathepsin B protease cleavable linker or a non-cleavable linker that may degrade intracellularly. Meth...
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WO/2017/066214A1 |
The present invention pertains to novel octahydro-indene compounds and their unexpected advantageous use thereof in enhancing, improving or modifying the fragrance of perfumes, colognes, toilet waters, fabric care products, personal prod...
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WO/2017/063327A1 |
The present invention provides a novel C-spiro-O-glycoside compound intermediate having a structural formula as shown in formula I. Also provided is a preparation method for the novel C-spiro-O-glycoside compound intermediate, comprising...
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