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Matches 1 - 50 out of 1,705

Document Document Title
WO/2022/144920A1
The present invention discloses Atovaquone prodrugs, process for the preparation of said prodrugs and pharmaceutical compositions comprising Atovaquone prodrugs. Atovaquone prodrugs of the present invention can be used alone, or co-admin...  
WO/2022/129185A1
The present invention generally relates to the production of vanillin and related compounds (such as aromatic carboxylic acids, quinones, etc.) involving the oxidative cleavage of aromatic compounds (such as lignin, lignols, cinnamic aci...  
WO/2022/107095A1
Disclosed are methods of treating pain, such as headaches, comprising administering an ergotamine and thymoquinone, wherein the ergotamine is selected from the group consisting of BOL-148, lysergic acid diethylamide (LSD), and lysergic a...  
WO/2022/104763A1
Provided process for cyclization of 2- (4' -alkylbenzoyl) benzoic acid to corresponding 2-alkylanthraquinone in the presence of an improved zeolite catalyst, which is capable of increasing the conversion of 2- (4' -alkylbenzoyl) benzoic ...  
WO/2022/091123A1
The present invention discloses compounds for inhibition of uncontrolled cell proliferation particularly cancer stem cells. Particularly, the invention relates to compounds of Formula (I) to (IV) for the treatment of cancer.  
WO/2022/057603A1
The present invention relates to a method for extracting coenzyme Q10 from a fermentation broth of coenzyme Q10, comprising subjecting the fermentation broth of coenzyme Q10 to pre-processing, leaching, crystallization, dissolution, chro...  
WO/2022/051291A2
Novel compounds which inhibit DYRK1A activity comprise thymoquinone derivatives including a pair of substituted or unsubstituted six-membered carbon rings selected from phenyl and cyclohexadiene linked by an alkyl or alkenyl linker. Each...  
WO/2022/015181A1
The invention relates to a method and intermediate compounds for the preparation of menaquinone MK-7. The method for the preparation of menaquinone MK-7 is characterized in that, it comprises coupling of a compound of formula (11) with a...  
WO/2021/238947A1
Disclosed is a method for preparing a quinone compound. The present invention provides a method for preparing a quinone compound, the method comprising the following step: in the presence of a base, subjecting a compound as shown in form...  
WO/2021/234078A1
The present invention relates to the photooxidation of 2,3,6-trimethyl- phenol to yield 2,3,5-trimethylbenzoquinone using methylene blue as photo- sensitizer in a solvent mixture of water and alcohols using light of the high wave- length...  
WO/2021/234077A1
The present invention relates to the photooxidation of 2,3,5-trimethyl- phenol to yield 2,3,5-trimethylbenzoquinone using methylene blue as photo- sensitizer in a solvent mixture of water and alcohols using light of the high wavelength r...  
WO/2021/234080A1
The present invention relates to the photooxidation of phenolic compounds to the respective quinoid compounds using methylene blue as photosensitizer in a solvent mixture of water and alcohols using light of the high wavelength range of ...  
WO/2021/232543A1
Disclosed is a method for separating coenzyme Q10 by means of using a supercritical fluid chromatography system, the method comprising: (1) starting a supercritical fluid chromatography system and setting system parameters; (2) once the ...  
WO/2021/202986A1
The disclosure provides therapeutic compounds, compositions (e.g., therapeutic agents or medicaments) and methods for preventing or treating mitochondrial disease such as Friedreich's ataxia in a mammalian subject, reducing risk factors,...  
WO/2021/175123A1
Disclosed are a 1,4-naphthoquinone compound for resisting novel coronavirus and the medical use thereof. The structure of the compound is as shown in formula (X): (X), wherein R1 is hydrogen, hydroxy, methoxy, ethoxy, benzyloxy, acetylox...  
WO/2021/173658A1
The present disclosure provides compounds of formula 1 to inhibit or prevent mitochondrial dysfunction by augmenting mitochondrial function. Mitochondrial dysfunction is the hallmark of a wide range of diseases and disorders. Mitochondri...  
WO/2021/161283A1
Described herein are compounds of Formula I: wherein R1-R6 are as described herein, for use in the treatment of a coronavirus infection; a method of inhibiting a coronavirus 3 CL protease, by contacting the 3 CL protease with a compound ...  
WO/2021/156406A1
The present invention relates to a process for preparing 8-hydroxy-9,10-dioxo-anthracene-1- carboxylic acid. It also relates to a method for preparing an anthraquinone derivative comprising a step for preparing 8-hydroxy-9,10-dioxo-anthr...  
WO/2021/122437A1
The present invention relates to the formation of 2,3,5-trimethylhydro- quinone from 2,3,6-tri¬methyl¬phenol comprising the steps a) the oxidation of 2,3,6-trimethylphenol to 2,3,5-trimethylquinone. b) the reduction of 2,3,5-trimethylq...  
WO/2021/126892A1
A method of oxygen scavenging, the method (i) providing an oxygen scavenger composition; and (ii) adding the oxygen scavenger composition to an aqueous feed and/or a hydrocarbon feed of a hydrocarbon processing system.  
WO/2021/119822A1
The present application relates to compositions comprising a bioactive lipophilic compound, an oil and at least one solubilizing agent that is a compound of Formula (I), to emulsions comprising such compositions and to uses thereof. The ...  
WO/2021/121135A1
Disclosed in the present invention are a photoinitiator, a preparation method therefor and an application thereof, and a photocurable composition. The photoinitiator has the structure represented by formula (I). The photoinitiator of the...  
WO/2021/120522A1
Disclosed in the present invention is a preparation method for vitamin K1 having different cis-trans isomer proportions and an intermediate halogenated phytol thereof. The method comprises: carrying out a halogenation reaction on a raw m...  
WO/2021/081500A1
The present invention provides novel mitochondria-targeted Atovaquone compounds (Mito-ATO), a mitochondria-targeted derivative of Atovaquone, and methods of using such compounds. Methods of treating cancer using mito-ATO are also provide...  
WO/2021/073456A1
Provided are a class of macrocyclic and cage-like molecules based on a biphenylarene and derivative compounds, a synthesis method therefor and the use thereof. A series of new macrocycles and molecular cages are obtained in a high yield ...  
WO/2021/071372A1
The invention relates to an improved process of vitamin K2 derivatives preparation via the alkylation of the menadione-cyclopentadiene adduct.  
WO/2021/067836A1
The disclosure provides therapeutic compositions (i.e., therapeutic agents) and methods of preventing or treating Friedreich's ataxia in a mammalian subject, reducing risk factors, signs and/or symptoms associated with Friedreich's ataxi...  
WO/2021/035342A1
Disclosed herein is a method for converting tetrahydrocannabinolic acid (THCA) to cannabinolic acid (CBNA). The method comprises contacting an input material comprising THCA with a benzoquinone reagent under reaction conditions comprisin...  
WO/2021/035344A1
Disclosed herein is a method for upgrading a cannabinoid mixture that comprises tetrahydrocannabinol (THC) and one or more non-THC cannabinoids, when the cannabinoid mixture has a THC content of less than about 20 wt. %. The method compr...  
WO/2021/036386A1
A simulated moving bed continuous chromatography system and an application thereof, and a method for purifying coenzyme Q10. The simulated moving bed continuous chromatography system comprises at least four chromatographic columns sequen...  
WO/2021/035340A1
Disclosed herein is a method of converting a THC-rich cannabinoid mixture that comprises at least about 20 % THC into a CBN-rich cannabinoid mixture that comprises at least about 2.0 % CBN. The method comprises contacting the cannabinoid...  
WO/2021/028506A1
The invention relates to processes for preparing 2 -methoxymethyl-p-phenylenediamine (I), cosmetically acceptable salts thereof, or mixtures thereof.  
WO/2021/000246A1
Provided is a Bacillus subtilis natto ST-1008, deposited under the accession number CGMCC No. 17894. Also provided is a method for producing MK-7. The method comprises: culturing the Bacillus subtilis natto of CGMCC No. 17894 in a cultur...  
WO/2020/132178A1
Described are methods and compositions for inhibiting polymerization of a monomer (e.g., styrene) composition using a hydroxylated quinone antipolymerant. The hydroxylated quinone antipolymerant can be used with little or no nitroxyl gro...  
WO/2020/130080A1
The purpose of the present invention is to provide a method for synthesizing a p-quinone using one of alkoxy-substituted benzenes as a starting material. The present invention relates to a method for producing a compound of formula (II...  
WO/2020/123432A1
Provided are improved methods for Vitamin K, including but not necessarily limited to MK-7 production through bacterial fermentation using biofilm reactors. Fed-batch addition of carbon sources, such as glucose, are used as the base medi...  
WO/2020/105500A1
The objective of the present invention is to provide a processing method for a working solution, wherein the amount of anthraquinones is increased by regenerating, into anthraquinones, by-products derived from anthraquinones and having n...  
WO/2020/103118A1
A process for manufacturing a compound of formula (II), said process comprising a step of reacting a compound of formula (I) in the presence of a zeolite catalyst and a solvent, (I), (II) wherein R1, R2, R3, R4, R5, R6, R7 and R8 are ind...  
WO/2020/081601A1
The disclosure provides methods of treating pancreatic cancer in a population of subjects comprising administration of Coenzyme Q10. Administration of Coenzyme Q10 to the subjects increases the number of subjects in the population that e...  
WO/2020/067333A1
To provide a novel therapeutic agent for fibrosis that induces selective cell death of lung fibroblasts without injuring alveolar epithelial cells and thus inhibits lung fibrosis. A pharmaceutical composition for treating fibrosis that c...  
WO/2020/067275A1
Provided is a method for producing a reduced coenzyme Q10 Form II-type crystal with high efficiency. A method for producing a reduced coenzyme Q10 crystal, comprising warming a mixture of a reduced coenzyme Q10 Form I-type crystal and a ...  
WO/2020/068735A1
Described are methods and composition for inhibiting polymerization of a monomer (e.g., styrene) composition using an aminated quinone antipolymerant, such as an aminated benzoquinone or aminated naphthoquinone antipolymerant having one ...  
WO/2020/055678A1
The present application discloses methods for the efficient preparation of high purity compounds of the Formula I, and their methods of use.  
WO/2020/041871A1
This application is directed to the use of a ketogenic agent, such as 1,3-butanediol, R-β-hydroxybutyl-R-β-hydroxybutyrate, or triheptanoin, in the treatment of an individual having a lysosomal storage disease, including Pompe disease....  
WO/2020/037372A1
A method of detecting the presence of an NBOMe in a sample which comprises of contacting the sample with an activated p-quinone such as 2,3,5,6-tetrachloro-1,4-benzoquinone (TCBQ) and an aldehyde, for example acetaldehyde, and optionally...  
WO/2020/025781A1
The present invention relates to a cocrystal of ubiquinone and a hydrogen bond donor coformer, to a process for the preparation thereof, and to its use as a medicament or a dietary supplement. The invention also relates to compositions c...  
WO/2020/015316A1
Disclosed are a method for extracting and purifying coenzyme Q10 and coenzyme Q10 prepared thereby. The method extracts and purifies coenzyme Q10 from coenzyme Q10 bacteria and comprises the steps of extracting, precipitating, decoloring...  
WO/2020/014776A1
An oral dispersible film composition comprising at least one active ingredient and a film forming agent, as well as a method of manufacture of same. The oral dispersible film composition can be free of gum resin, and can be utilized to a...  
WO/2019/231735A1
Provided are colored 1,4-benzoquinone compounds obtained by oxidation of precursor molecules from the venom of the scorpion Diplocentrus melici (Diplocentridae family). Schemes for the chemical synthesis of these compounds using reagents...  
WO/2019/222146A1
In some embodiments of the invention, inventive compounds (e.g., Formula (I), (IA), (II), and (III), and urolithin derivatives) are disclosed. Other embodiments include compositions (e.g., pharmaceutical compositions) comprising the inve...  

Matches 1 - 50 out of 1,705