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Matches 301 - 350 out of 8,141

Document Document Title
WO/2019/172360A1
The present invention addresses the problem of providing a method for producing a carbonyl compound. Provided is a method for producing a carbonyl compound represented by formula (1) [in the formula, R1 is hydrogen or an organic group; R...  
WO/2019/171093A2
The invention relates to a robust and reproducible process for the preparation of polymorph form B of treprostinil diethanolamine salt, comprising the following steps: a. treprostinil is dissolved in methanol, b. to the solution of step ...  
WO/2019/171277A1
The present invention is directed to cycloalkenyl derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the GPR120 and / or GPR40 receptors. 5 More particularly, ...  
WO/2019/154624A1
New process of producing alpha-hydroxy compounds from sustainable resources useful as platform chemicals, such as hydroxy analogues of amino acids or polymer precursors.  
WO/2019/146801A1
The present invention provides a compound represented by general formula (1) or a salt thereof. [In general formula (1), R1 and R2 represent an aldehyde group, a carboxyl group, or a C1-6 alkyl group, and at least one of R1 and R2 is an ...  
WO/2019/142941A1
Provided is a method of producing, by means of a simple drying operation, high-purity ferric citrate which retains a high specific surface area while having a reduced water soluble organic solvent content. This method of producing ferric...  
WO/2019/138338A1
The present patent application discloses a new and innovative method for purification of glycerol derivatives, by simulated moving bed chromatography. The method of the present patent application allows the separation of at least one gly...  
WO/2019/138989A1
Provided is an industrially advantageous method for producing a titanium chelate compound, with which a titanium chelate compound can be obtained efficiently, with fewer steps and higher productivity. This method for producing a titanium...  
WO/2019/136435A1
Disclosed are surface retarder composition and method for etching cementitious materials which achieve a desirable light "acid etch" look without using muriatic (hydrochloric) acid or sand blasting, removing the human health and environm...  
WO/2019/121134A1
The present invention relates to the manufacturing of a process of alkyl 2- acetyl-5,9,13-trimethyltetradeca-4,8,12-trienoates and alkyl 2-acetyl-9,13-di- methyl-5-methylenetetradeca-8,12-dienoate as well as 6,10,14-trimethylpenta- deca-...  
WO/2019/120235A1
The present invention relates to a class of phenylcarboxylic acid derivatives, a preparation method therefor and a use thereof, more specifically relating to a class of phenylcarboxylic acid derivatives as shown in formula I, a preparati...  
WO/2019/113693A1
Compounds that are inhibitors of retinoic acid inducible P450 (CYP26) enzymes. The compounds have retinoid activity, are resistant to CYP26-mediated catabolism, act as inhibitors of CYP26B1, and are used for treating diseases that are re...  
WO/2019/113383A1
The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including, reactive oxygen species (ROS)-mediated dis...  
WO/2019/105780A1
Composition containing (A) at least one salt of an organic ester of choline or of a derivative of choline, and (B) at least one surfactant selected from amphoteric and anionic and non-ionic surfactants.  
WO/2019/108605A1
The present invention relates to compounds of Formulas I- IV, which are salts of special lipid mediators of inflammation, compositions containing same, and methods of using same in the treatment of various diseases and disorders characte...  
WO/2019/093491A1
The purpose of the present invention is to provide a production method by which ferric citrate hydrate having various specific surface areas is efficiently obtained with high purity. The present invention provides a method for producing ...  
WO/2019/090059A1
Provided are solid forms of a compound useful for treating cancer, pharmaceutical compositions thereof, and methods of treating cancer comprising administering the solid forms described herein to a patient in need thereof.  
WO/2019/087487A1
The purpose of the present disclosure is to provide a recovery method that makes it possible to individually recover excrement and an organic acid from a deactivating aqueous solution that includes the excrement and the organic acid. Thi...  
WO/2019/083001A1
The present invention provides: a method for producing a benzoyl formic acid compound in an industrially advantageous manner; and a method for efficiently producing a pyridazine compound using the method for producing a benzoyl formic ac...  
WO/2019/081972A1
Preparation of a salt of 4-nitrophenyl ethylamine with (R)-mandelic acid and its use for the synthesis of mirabegron is disclosed. 4-Nitrophenyl ethylamine (1) is prepared by reduction of 4-nitrobenzyl cyanide (7) in a solvent with the u...  
WO/2019/082129A1
The disclosure provides methods and apparatus for producing 3-hydroxypropionic acid or a salt thereof, for removing 3-hydroxypropionic acid from aqueous solution (e.g., aqueous broth), and for using it to make various chemicals.  
WO/2019/068798A1
The invention relates to a particulate product comprising at least 10 wt.% of the coated lactate particles having the following characteristics: - comprising one or more carrier particles containing at least 80 wt.% of calcium lactate co...  
WO/2019/047113A1
Provided is a process for oxidation of alcohols in the presence of a noble metal catalyst. The process allows desired alcohol oxidation reaction to obtain the corresponding carboxylic acid with a high yield and avoids problems associated...  
WO/2019/049138A1
The present invention provides methods for chemical synthesis of a resolvin compound such as resolvin E1 (RvE1), or a pharmaceutically acceptable salt thereof; and chemically stable formulations of said compound.  
WO/2019/050407A1
The invention is directed to a method for producing lactate. The method of the invention comprises electrochemically oxidising a catalyst at an anode, and using oxidised catalyst to oxidise propylene glycol and form lactate, thereby redu...  
WO/2019/047654A1
The present invention belongs to the field of drug synthesis, and relates to a method for preparing a substituted phenylacetic acid derivative, specifically a method for preparing 2-[4-(2-oxopentylmethyl)phenylpropionic acid]. A precurso...  
WO/2019/043060A1
The present invention relates to binaphthyl compounds of the formula (I), which are suitable as monomers for preparing polycarbonate resins having beneficial optical properties and which can be used for producing optical lenses: Formula ...  
WO/2019/038637A1
The present disclosure discloses various salts of levodopa amide, and crystalline forms thereof, and pharmaceutical compositions comprising the salts or crystalline forms, which are useful in treatment of diseases or disorders characteri...  
WO/2019/034673A1
The present invention is directed to stable lyophilisates comprising 5,10-methylene-(6R)-tetrahydro folic acid or a pharmaceutically acceptable salt thereof and a dicarboxylic acid, or a salt thereof, as well as, a processes of obtaining...  
WO/2019/035989A1
Disclosed herein are methods for preventing or treating calcium oxalate kidney stones in a subject by administrating a composition comprising an effective amount of potassium hydroxycitrate (KOHCit). KOHCit increases urinary pH mildly to...  
WO/2019/025535A1
The present invention in general relates to a method for the deacylation and/or dealkylation (both O-dealkylation as well as C-dealkylation) of compounds, more specifically of aromatic compounds. The method is characterized by contacting...  
WO/2019/025017A1
The present invention relates to a process for the preparation of elafibranor and novel synthesis intermediates.  
WO/2019/023481A1
Compounds of Formula (I) are provided herein. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions, including conditions characterized by excessive cellular...  
WO/2019/020773A1
The present invention relates to a new bio-sourced vanillin and/or ethylvanillin, containing specific impurities. The invention further relates to a process for their preparations and the use of such compounds.  
WO/2019/016883A1
The purpose of the present invention is to provide a method for preparing a 3-hydroxy-3-methylbutanoic acid or a salt thereof, the method being capable of efficiently preparing a highly pure 3-hydroxy-3-methylbutanoic acid or a salt ther...  
WO/2019/016983A1
The purpose of the present invention is to provide a method for preparing a 3-hydroxy-3-methylbutanoic acid or a salt thereof, the method being capable of efficiently preparing a highly pure 3-hydroxy-3-methylbutanoic acid or a salt ther...  
WO/2019/010414A1
This disclosure concerns fatty acid derivatives, pharmaceutical compositions comprising the fatty acid derivatives, and methods of using the fatty acid derivatives, for example, to treat inflammation, chronic itch, chronic pain, an autoi...  
WO/2019/008002A1
The invention relates to a composition comprising a) a polymer and b) (i) a phenolic metal salt of formula (I) Mn+ (L-)n wherein n is 1, 2 or 3, Mn+ is a metal ion and L- is an anion of formula (II) wherein A1 and A2 are both -CH2-CH2-, ...  
WO/2019/002189A1
The invention also relates to alkoxylated hydroxy carbon acids and to a method for the production and use thereof.  
WO/2018/236950A1
A method is provided for separating a dicarboxylic acid product from a mixture containing such dicarboxylic acids. The method involves: providing a dicarboxylic acid-containing mixture of which at least 35% of the carboxylic acid content...  
WO/2018/235012A1
Process for producing levulinic acid, wherein a carbohydrate-based substrate is subjected to a treatment step in aqueous environment at acid pH at a temperature from 120°C to 200°C, so as to obtain a reaction mixture comprising levulin...  
WO/2018/229013A1
The invention concerns a method for obtaining a free glucaric acid solution from a solution comprising non-free glucaric acid, water and at least one other constituent including at least one ion, characterised in that it comprises the fo...  
WO/2018/228149A1
The present invention belongs to the field of pharmaceutical synthesis, and relates to a preparation method for a substituted phenylacetic acid derivative, in particular to a method for preparing 2-[4-(2-oxopentylmethyl)phenylpropionic a...  
WO/2018/226102A1
The present invention is directed to methods for the preparation of eremophila-1(10)-11(13)-dien-12,8β-olide (EPD) and analogues thereof.  
WO/2018/222785A1
Porous calcium lactate metal-organic frameworks (MOFs) comprise non-toxic metal ions - Ca(II) and non-toxic, renewable and cheap linkers - lactate and acetate. The MOFs are nontoxic and environmentally-benign, and can be used as degradab...  
WO/2018/218963A1
Provided in the present invention are a pharmaceutically acceptable salt of an epidermal growth factor receptor (EGFR) inhibitor, a crystal form thereof, a preparation method therefor and an application thereof. The structural formula of...  
WO/2018/212624A1
The present invention relates to a 11-lipoxygenase consisting of the amino acid sequence represented by SEQ ID NO: 1; or a composition for producing 11-hydroxyfatty acid, hepoxilin D3, or trioxilin D3, comprising the 11-lipoxygenase and ...  
WO/2018/205037A1
The present description relates to genetic tools and methods to facilitate transformation and genetic engineering of industrially-useful yeast/fungal species, such as Issatchenkia orientalis, for which a robust set of genetic tools such ...  
WO/2018/195163A1
This present invention provides gemcabene pharmaceutically acceptable salts having a PSD90 of 35 µm to about 90 µm, methods for purifying crude gemcabene, pharmaceutically acceptable salts of purified gemcabene, pharmaceutical composit...  
WO/2018/195422A1
A process for a reactive separation of organic molecules from biomass includes a reaction step for the biomass, a simultaneous extraction step using a solvent, and a filtration step to recover products, wherein the products comprise feru...  

Matches 301 - 350 out of 8,141