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JP4090215B2 |
Production of (R)- and (S)- alpha -hydroxycarboxylic acids (I) of optical and chemical purity comprises recrystallizing crude material in an aromatic hydrocarbon (II), to give (I) of optical purity over 98% enantiomeric excess (ee). The ...
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JP4074155B2 |
A 4-membered compound is represented by the following formula (I) is disclosed (in the formula, X<1> and X<2> each independently represent an oxygen atom, a sulfur atom or a substituted or unsubstituted imino group, Y<1> and Y<2> each in...
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JP4067251B2 |
The present invention relates to novel monomers which can be used to form photoresist polymers and photoresist compositions using the same which are suitable for photolithography processes employing a far ultraviolet light source, copoly...
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JP4046610B2 |
Compounds and compositions comprising specific metal salts of hexahydrophthalic acid (HHPA) in order to provide highly desirable properties within thermoplastic articles are provided. The inventive HHPA derivatives are useful as nucleati...
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JP4032220B2 |
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JP2007332068A |
To obtain a new fluoroadamantane derivative and to provide a method for producing the same. The method for producing a compound represented by formula (5) comprises reacting a compound represented by formula (6) with a compound represent...
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JP2007302727A |
To provide a new inclusion material and an inclusion method. The inclusion material contains a host molecule having an inclusion action to a guest molecule. The host molecule is a cyclic polymethacrylic acid oligomer. The guest molecule ...
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JP4001432B2 |
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JP3993427B2 |
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JP3985603B2 |
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JP2007525408A |
The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders c...
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JP3927772B2 |
The present invention relates to the use of certain resorcinol derivatives as skin lightening agents.
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JP2007506551A |
Separation of organic compound(s) (I), useful as active agents, from a (I)-containing substrate (A) comprises treating (A) with an extractant (B) comprising at least one fluorinated compound (II) having a b. pt. of 25[deg]C or more under...
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JP2007023040A |
To provide a method for producing an optically active 3,4-disubstituted cyclopentanone, and to provide a material for producing the same.The method for producing the optically active 3,4-disubstituted cyclopentanone comprises hydrolyzing...
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JP3847336B2 |
PCT No. PCT/EP95/02684 Sec. 371 Date Jan. 15, 1997 Sec. 102(e) Date Jan. 15, 1997 PCT Filed Jul. 11, 1995 PCT Pub. No. WO96/03366 PCT Pub. Date Feb. 8, 1996The present invention relates to novel substituted bicyclic 2-mesityl-cyclopentan...
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JP3847335B2 |
The present invention relates to novel 2-aryl-3-hydroxy-cyclopent-2-en-1-one derivatives of the formula (I) in which X represents halogen, nitro, cyano, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl ...
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JP2006524220A |
This invention relates to compounds that alter PPAR activity. The invention also relates to pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods...
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JP3836508B2 |
Halogenated compounds are prepared by ring opening reactions of highly fluorinated cyclopropanes with chlorine, bromine, iodine, or mixtures thereof at temperatures over 100 DEG C. A novel compound, which is one type of compound produced...
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JP2006523671A |
Alpha substituted carboxylic acids of formula (I): wherein R' and R2 are as defined in the specification and R3 is A) formula (II); B) formula (III); C) formula (IV); and D) formula (V); wherein Y, Art, Are, AP, R4, R5, R6, R7, R6, R9, R...
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JP2006257001A |
To efficiently carry out a gas-liquid reaction in a gas-liquid coexistence system of a liquid containing a reactant and a reacting gas.The gas-liquid reaction method involves reacting the reactant in the liquid phase with the reacting ga...
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JP3822350B2 |
To obtain efficiently and inexpensively purified quinic acid, by reacting crude quinic acid with a ketone or an aldehyde in the presence of an acid catalyst to derive a specific quinic acid acetal derivative, purifying and then hydrolyzi...
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JP3807605B2 |
To provide a compound capable of being utilized as an intermediate for producing a cyclopropane carboxylate ester which is an insecticidally active compound known as pyrethroids, and being observable because of having very good insectici...
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JP2006516133A |
The present invention provides compounds capable of binding to an Fc receptor and modulating Fc receptor activity comprising a core lipophilic group in the form of an Aryl zing substituted with a group rich in p-electrons. The invention ...
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JP3769737B2 |
PURPOSE: To obtain a new compound useful as an antiviral agent. CONSTITUTION: This is a compound of formula I (B is a purine derivative residue such as guanine-9-yl, 2-amino-6-chloropurine-9-yl and 2-acetamino-6- chloropurine-9-yl), e.g....
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JP2006089454A |
To provide a cyclopropanecarboxylic acid compound having a specified structure, and to provide a method for producing the compound, capable of safely synthesizing the compound at a low cost in a high yield.This cyclopropanecarboxylic aci...
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JP2002504538A5 |
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JP3747493B2 |
PURPOSE: To industrially and advantageously obtain a carboxylic acid useful as a raw material, etc., of a solvent-soluble type polyimide in high purity and yield at a short time by carrying out hydrolysis of an alicyclic polycarboxylic e...
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JP3744536B2 |
Process for the hydroformylation of ethylenically unsaturated compounds, by reaction with carbon monoxide and hydrogen in the presence of a catalyst based on a metal of the platinum group, a source of anions other than halide anions and ...
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JP2004503498A5 |
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JP3720735B2 |
To provide a new 1,1- and 1,2-disubstituted cyclopropane compound having specific interaction with central nicotinic receptors of type α4β2. This compound is represented by formula (1), and concretely exemplified by 2-[1-(dimethylamino...
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JP2005314431A |
To provide new 1,1- and 1,2-disubstituted cyclopropane compounds which specifically interact on central nicotine-like receptors of type α4β2.The compound of formula (I) (the marks in the formula are specially defined). The pharmaceutic...
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JP3684429B2 |
PURPOSE: To obtain new substd. cyclohexane derivs. which inhibit the glucose-6- phosphatase system of the liver of a mammal and are useful as pharmaceuticals of type II diabetes. CONSTITUTION: The substd. cyclohexane derivs. are compds. ...
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JP3641384B2 |
To obtain shikimic acid and its derivative useful as an intermediate for synthesizing a pharmaceutically active compound while attaining high selectivity in the dehydrated position by dehydrating quinic acid by means of Vilsmeier reagent...
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JP3618104B2 |
The present invention provides the use of an agonist which acts at negatively coupled cAMP-linked metabotropic glutamate receptors for the manufacture of a medicament for the treatment of substance dependence disorders.
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JP3614435B2 |
The present invention provides a method of treating anxiety and related disorders using an agonist which acts at negatively coupled cAMP-linked metabotropic glutamate receptors.
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JPWO2003029391A1 |
The present invention comprises extracting and treating olive plants and / or by-products obtained in the olive oil production process with an organic solvent or a hydrous organic solvent, such as oleanolic acid, maslinic acid, physiolog...
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JP3610483B2 |
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JP2004307417A |
To provide a method for producing a fullerene derivative having a hydrogen atom and a hydroxy group added thereto.The method for producing the fullerene derivative involves oxidizing a hydrogenated fullerene. The fullerene derivative hav...
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JP3571376B2 |
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JP2004525606A |
In the production of genetically-modified, non-pathogenic organisms particularly an improved production and isolation of trans-dihydroxycyclohexadiene carboxylic acids and/or derivatives thereof, the synthesis of the transhydroxy cyclohe...
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JP3529095B2 |
A plant growth promoter containing a jasmonic acid derivative represented by general formula (I) as the active ingredient (wherein R<1> represents pentyl or pentenyl; and R<2> represents hydrogen or alkyl). It has an excellent growth-pro...
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JP2004509160A |
The present invention is directed to certain novel compounds represented by structural formula I:or a pharmaceutically acceptable salt thereof, wherein R3, R5, R6, R7, R8, R11, R12, R13, Q, W, X, Y and Z are defined herein. The invention...
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JP2004503498A |
The present invention relates to cannabidiol derivatives and to pharmaceutical compositions comprising cannabidiol derivatives being antiinflammatory agents having analgesic, antianxiety, anticonvulsive, neuroprotective, antipsychotic an...
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JP2004502663A |
Compounds of formula (I), wherein R1 and R2 are, independently of one another, H, C1-C6alkyl, C1-C6halogenalkyl, C1-C6alkoxy, C1-C6alkoxy-C1-C6alkyl, or C1-C6alkoxy-C1l-C6alkyloxy, and R3 is C1-C6alkyl, are obtainable in high yields by s...
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JP3481255B2 |
Compounds represented by formula (I), and pharmaceutically acceptacle salts thereof; and their method of preparation are provided. Compounds of the above formula are influenza virus neuraminidase inhibitors and can be used in treating pa...
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JP3457005B2 |
PCT No. PCT/DK96/00326 Sec. 371 Date Jan. 20, 1998 Sec. 102(e) Date Jan. 20, 1998 PCT Filed Jul. 17, 1996 PCT Pub. No. WO97/03941 PCT Pub. Date Feb. 6, 1997The compounds 3-(2,2-dichloro-3,3,3-trifluoro-1-hydroxypropyl)-2,2-dimethy
l-(1R,...
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JP2003530303A |
Salts of asiatic and madecassic acid with pharmaceutically acceptable organic bases, suitable for the preparation of pharmaceutical and cosmetic compositions for the topical and systemic treatment of erithema, varicose ulcers, venous ins...
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JP3453188B2 |
PURPOSE: To industrially and advantageously obtain an oleanolic acid useful as a production intermediate, etc., for endothelin receptor antagonism, etc., by reducing a specific steroidal lactone compound with an alkali(earth)metal in an ...
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JP2003277315A |
To provide a method for producing a hydroxycarboxylic acid compound, capable of directly hydrogenating a dicarboxylic acid compound under a relatively mild condition so as to produce the hydroxycarboxylic acid compound corresponding to t...
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JP2003267915A |
To provide a method for the industrial production of a 3,3-dimethyl-2- formylcyclopropanecarboxylic acid derivative expressed by general formula (2) (R is H, a (substituted)alkyl, a (substituted)aryl or a (substituted)aralkyl).The 3,3-di...
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