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Matches 501 - 550 out of 1,006

Document Document Title
JPH11349583A
To produce a quinic acid derivative useful as a pharmaceutical intermediate effectively at a low cost by converting a quinic acid component of a crude quinic acid containing an inorganic salt in a large amount extracted from an extractio...  
JP2966978B2
Hydrophobic casting moulds are treated with electrical discharge, such as corona discharge, to provide enhanced compatibility with hydrophilic objects introduced into the mould, without interfering with the release properties of the moul...  
JPH11240851A
To obtain the subject new compound useful as an optical material having excellent heat resistance, transparency and moisture resistance. This compound is shown by formula I ((n) is 1 or 2; R1 to R3 are each H or a 1-6C hydrocarbon). The ...  
JPH11508559A
A process for the preparation of (+)-2-amino-bicycloÄ3.1.0Ü-hexane-2-6-dicarboxylic acid, or a pharmaceutically acceptable salt thereof, which comprises hydrolysing (-)-2-spiro-5'-hydantoinbicycloÄ3.1.0Ühexane-6-carboxylic acid or a ...  
JPH11180930A
To obtain the subject compound by reacting racemic-trans- cyclobutanedicarboxylic acids with an optically active amine to deposit either one diastereomeric salt and subjecting the salt to acid decomposition to directly optically resolve ...  
JP2907144B2  
JPH11140014A
To provide a process for separating expensive quinic acid useful as a food additive, industrial material, pharmaceutical raw material and cosmetic material from a raw material liquid in high efficiency in purified state. This process com...  
JP2895462B2
An enantioselective process for preparing trans or cis hemicaron aldehyde derivatives, starting with an alpha-beta unsaturated ester derived from glyceraldehyde acetonide, by the action of a cyclopropanation agent, as well as new interme...  
JPH11130713A
To obtain the subject new compound useful as an agent for preventing and treating diabetic complications and as an aldose reductase inhibitor. A compound of formula I [R1 and R2 are each hydroxy, a (aryl-substituted) lower alkoxy or a ha...  
JPH11106360A
To obtain the subject new compound useful as a raw material for electroconductive polymers, photographic photo-sensitive materials, fluorescent materials, transparent resin coatings for organic glasses, optical materials for optical fibe...  
JP2883297B2
To obtain the subject novel compound, which affect certain excitatory amino acid receptors and are useful for treatment of neurological and psychiatric disorders. This compound is shown by formula I [X is (CH2)n; R2 is CO2R4 when R3 is H...  
JP2880670B2
The invention relates to the use of carnosic acid for the production of a composition intended for preventing or treating cancer and for treating herpes.  
JP2867257B2
The invention provides a process for the preparation of fungicidally active cyclopentene derivatives of the general formula cyclopentane derivatives of the general formula and cyclohexane derivatives of the general formula in which n, R,...  
JP2863786B2  
JP2864698B2  
JP2863175B2
An enantioselective process for preparing trans or cis hemicaron aldehyde derivatives, starting with an alpha-beta unsaturated ester derived from glyceraldehyde acetonide, by the action of a cyclopropanation agent, as well as new interme...  
JP2864491B2  
JPH1149718A
To obtain the subject new derivative useful as a therapeutic agent for the central neuropathy or peripheral neuropathy. This derivative is represented by formula I (A-ring has one double bond conjugated with oxo group; X is O, S or the l...  
JPH1121267A
To obtain the subject compounds in high yield, high purity and low in cost useful as intermediates of medicines and agrochemicals by reacting quinic acid derivatives with reagents having dehydrating capability. The (-)-shikimic acid prec...  
JP2848375B2
To obtain the subject derivative, an 1,3,5-triphenylpyrazolyl derivative, having arachidonic acid metabolic route-inhibitory activity, and useful as e.g. an agent for mitigating inflammation, asthma, anaphylaxis, myocardial ischemia, der...  
JPH10330266A
To obtain a composition having activity for enhancing insulin action and differentiation-inducing activity by including a compound having lanostane skeleton or 3,4-secolanostane skeleton as an active ingredient. This composition has at l...  
JP2835731B2
1,4-disubstituted piperidinyl compounds of formula I useful as antiarrhythmics, analgesics, and serotonin 5HT2 antagonists.  
JPH10316609A
To easily produce the subject compound that is useful as a synthetic starting material for 2-norbonanone to be used as a synthetic starting material of a variety of pharmaceuticals and agrochemicals by using di-substituted methyldioxolan...  
JP2831358B2
An enantioselective process for the preparation of hemicaronic aldehyde with a cis or trans structure and novel intermediates.  
JP2828295B2
Pentacyclic triterpenoid compounds such as alpha -boswellic acid and its acetate, beta -boswellic acid and its acetate, which have an inhibitory effect on topoisomerase I and topoisomerase II, are disclosed. Compositions based on the pen...  
JPH10511388A
PCT No. PCT/US95/13319 Sec. 371 Date Jun. 23, 1997 Sec. 102(e) Date Jun. 23, 1997 PCT Filed Oct. 10, 1995 PCT Pub. No. WO96/20156 PCT Pub. Date Jul. 4, 1996The present invention relates to novel 3,3-(disubstituted)cyclohexan-1-carboxylat...  
JPH10511398A
PCT No. PCT/US95/16857 Sec. 371 Date Oct. 6, 1997 Sec. 102(e) Date Oct. 6, 1997 PCT Filed Dec. 21, 1995 PCT Pub. No. WO96/19990 PCT Pub. Date Jul. 4, 1996The present invention relates to novel 4,4-(disubstituted)cyclohexan-1-carboxylate ...  
JPH10511392A
(57) -- summary book invention is new -- a 4 and 4* (2 substitution) cyclohexane *1* carboxylate dimer and a related compound --It is related with those use for the medical treatment of the medicine composite containing these compounds, ...  
JP2809620B2
To provide the subject new compound useful as an inert fluid. This compound is expressed by the formula I (Z is COOCH3, COOC2H5 or COOC2H4OCH3), e.g. dimethyl 1,3-perfluorocyclohexanedicarboxylate of the formula II. The objective compoun...  
JPH10510656A
Compounds, methods and compositions are provided for inducing natriuresis in a mammal. Methods for isolating and synthesizing the natriuretic compounds are also provided. Therapeutic methods using the natriuretic compounds are also provi...  
JP2808322B2
The invention provides a process for the preparation of fungicidally active cyclopentene derivatives of the general formula cyclopentane derivatives of the general formula and cyclohexane derivatives of the general formula in which n, R,...  
JPH10509959A
The object of the present invention is to provide asiatic acid derivatives, its pharmaceutically acceptable salts or esters. Asiatic acid, its trisaccharide asiaticoside and mddecassic acid, extracted from Centella asiatica have been use...  
JPH10509146A
Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The presently claimed compounds have the generalized formula in which each ...  
JP2790479B2
Compounds of the general formula A- @-B wherein A is a bicyclic 1-one-2-ene-3-ol-2-yl residue; B is an aryl or heteroaryl group optionally bearing substituents; and salts, enolethers and enolesters thereof, and methods of producing such ...  
JP2788657B2  
JP2788427B2
PURPOSE: To provide a method for recovering quinic acid in high efficiency and purity from a stock liquid containing sodium sulfate and quinic acid, dispensing with the marine disposal of a waste liquid discharged in the production of ga...  
JP2774381B2  
JPH10182546A
To obtain a new azulene derivative having excellent antiinflammatory, antipyretic, analgesic, and antarthritic actions and little in side effects such as gastrointestinal disorders. An azulene derivative of formula I [R1 is a (substitute...  
JPH10506383A
Compounds, methods and compositions are provided for inducing natriuresis in a mammal. Methods for isolating and synthesizing the natriuretic compounds are also provided. Therapeutic methods using the natriuretic compounds are also provi...  
JPH10505597A
The present invention provides compounds of formula (I) in which R is as defined in the specification, or a pharmaceutically acceptable metabolically labile ester or amide thereof, or a pharmaceutically acceptable salt thereof, which are...  
JPH10505610A
An improved process for the preparation of R(+)1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenyl-3-cyclohexen-1- yl)methyl]pyridine by a novel synthesis is described where 5-oxo-3-phenyl-3-cyclohexene-carboxylic acid is converted in five operatio...  
JP2758902B2
This invention encompasses compounds of Formula 1 and the pharmaceutically acceptable salts thereof. wherein R<1> represents alkyl having 2-6 carbon atoms; R<2> represents methyl or ethyl; R<3> represents alkyl having 1 to 5 carbon atoms...  
JP2756971B2  
JP2740919B2
Novel platinum complexes of the formula: wherein R<1> and R<2> are identical or different lower alkyl groups, or R<1> and R<2> taken together form a -(CH2)m- bridge, and m is an integer from 2 to 5, and antitumor agents comprising the co...  
JP2740829B2  
JPH1087548A
To make it possible to obtain the subject compound useful for producing medicines and agrochemicals with excellent yield and purity without requiring severe reactional conditions by using a catalytic transfer hydrogenation. (A) A 1,3-dih...  
JP2717787B2
Dimethyl cyclopropane carboxylic acid derivs. of formula (I) mare new. X1 and X2 are each halogens, R1 = halogen, alkyl of up to 8C, aryl of up to 14C, that may be substd. perfluoroalkyl of up to 8C, -CN, -COOR' (R' = alkyl of up to 8C),...  
JP2710097B2
PURPOSE: To produce a compound useful for exterminating parasites, nematodes and mites by reacting cyclopropanecarboxylic acids with a reducing agent. CONSTITUTION: A compound represented by formula I (X1 and X2 are each a halogen; R1 is...  
JP2708118B2
Di- and tri-substituted perfluorocycloalkane compounds which have a cyclohexane or decahydronaphthalene nucleus are provided. These perfluorocycloalkane compounds are carbonyl fluorides and derivatives thereof.  
JP2705792B2
Bicyclic aromatic compound having the formula (R) wherein R1, R2, R3 and R4 represent hydrogen or alkyl, at least two of R1-R4 radicals being other than hydrogen, A represents methylene or dimethylene; when A represents dimethylene, R1 a...  

Matches 501 - 550 out of 1,006