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Matches 551 - 600 out of 1,014

Document Document Title
JP2756971B2  
JP2740919B2
Novel platinum complexes of the formula: wherein R<1> and R<2> are identical or different lower alkyl groups, or R<1> and R<2> taken together form a -(CH2)m- bridge, and m is an integer from 2 to 5, and antitumor agents comprising the co...  
JP2740829B2  
JPH1087548A
To make it possible to obtain the subject compound useful for producing medicines and agrochemicals with excellent yield and purity without requiring severe reactional conditions by using a catalytic transfer hydrogenation. (A) A 1,3-dih...  
JP2717787B2
Dimethyl cyclopropane carboxylic acid derivs. of formula (I) mare new. X1 and X2 are each halogens, R1 = halogen, alkyl of up to 8C, aryl of up to 14C, that may be substd. perfluoroalkyl of up to 8C, -CN, -COOR' (R' = alkyl of up to 8C),...  
JP2710097B2
PURPOSE: To produce a compound useful for exterminating parasites, nematodes and mites by reacting cyclopropanecarboxylic acids with a reducing agent. CONSTITUTION: A compound represented by formula I (X1 and X2 are each a halogen; R1 is...  
JP2708118B2
Di- and tri-substituted perfluorocycloalkane compounds which have a cyclohexane or decahydronaphthalene nucleus are provided. These perfluorocycloalkane compounds are carbonyl fluorides and derivatives thereof.  
JP2705792B2
Bicyclic aromatic compound having the formula (R) wherein R1, R2, R3 and R4 represent hydrogen or alkyl, at least two of R1-R4 radicals being other than hydrogen, A represents methylene or dimethylene; when A represents dimethylene, R1 a...  
JP2693843B2
The present invention includes compounds represented by the formula: wherein n is 0 or 1; R1, R2, R3, and R4 are independently selected from hydrogen, hydroxy, amino, alkylamino, alkylsulfonylamino, loweralkyl, loweralkoxy, halo, and thi...  
JP2681648B2  
JPH09278708A
To obtain a sesquiterpene-based compound useful as a raw material for a medicine, especially an antibacterial agent or an antifungal agent. This sesquiterpene-based compound is shown by formula I (R is H, ammonium, an alkali metal or a l...  
JP2668796B2
2- and 3-substituted (1 min ,5 min -diaryl-3 min -pyrazolyl)-N-hydroxypropanamides, a method for their preparation, compositions containing the same and methods of their use are disclosed. The N-hydroxypropanamides are useful in alleviat...  
JP2667294B2
Indane and indene derivs. of formula (I) and their salts are new. In (I), R1 = X(CH2)nAr, X(CH2)nR8 or a gp. (a); R2 = H, Ar or (a); P1 = X(CH2)nR8; P2 = X(CH2)nR8 or XR9Y; R3, R5 = R11, H, OH, 1-8 alkoxy, S(O)qR11, N(R6)2, Br, F, I, Cl,...  
JP2644818B2  
JP2637113B2  
JPH09183724A
To obtain a uzedicine useful as an antitumor agent and expected as an antitumor medicine having high safety and little side effect by compounding a specific naphthalene carboxylic acid derivative obtained from propolis or its salt as an ...  
JPH09506864A
Compounds of Formula 1 Formula 1 wherein m is 1-4; R1-R4 independently are hydrogen, lower alkyl of 1 to 6 carbons, Cl, Br, or I; R5 is hydrogen, lower alkyl of 1 to 6 carbons, Cl, Br, I, lower alkoxy or lower thioalkoxy of 1-6 carbons; ...  
JP2622135B2
Indene derivatives of the general formula wherein R<1> is a) a phenyl group optionally substituted with one or more groups selected from halogen, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulfonyl, dilower alkylamino, acylam...  
JP2621309B2  
JPH09124489A
To obtain the subject agent containing a specific saponin as an active ingredient, capable of suppressing the production of interleukin-6 caused by a stimulation with various physiological materials, and anticipated as a therapeutic agen...  
JPH09104693A
To obtain new glycosides having action capable of controlling immune system of warm-blooded animals and usable as an active substance in medicines for treating tumor and viral diseases by separating from an aqueous extract of a plant pol...  
JP2599413B2  
JP2587902B2
PURPOSE: To obtain a new 1-phenylbicyclo[2,2,2]octane compound useful for the treatment of arthritis and inflammatory phenomenon due to denaturation of acute phase protein. CONSTITUTION: The compound of formula I [R1 is a halogen, OH, 1-...  
JP2583241B2  
JPH0940606A
To obtain the subject compound effectively, without producing by- products and causing the problem of the corrosion of an apparatus, and useful as an intermediate, etc., for a liquid crystal through the hydrogenation of the aromatic ring...  
JP2572173B2
The invention relates to the use of carnosic acid for the production of a composition intended for preventing or treating cancer and for treating herpes.  
JP2559723B2
Vinylphenol derivatives of the formula I where A and R1 to R7 have the meanings stated in claim 1 and in the description, and their physiologically tolerated salts, drugs prepared from these, and their use for the treatment of various di...  
JPH08283116A
PURPOSE: To obtain a skin lightener and a skin cosmetic which have excellent skin-lightening effect and can prevent and treat skin spots and ephelis caused by sun burn by using a specific 1,3-diarylindan-2-carboxylic acid. CONSTITUTION: ...  
JP2546992B2  
JPH08509220A
Novel cyclopentane derivatives are described which are endothelin receptor antagonists.  
JP2533565B2  
JP2523140B2  
JP2521191B2
New phenylethanolaminomethyltetralins of formula (I) (I) wherein E represents hydrogen, (C1-C4)alkyl, (C1-C4)alkoxy, phenyl, nitro, halogen, or trifluoromethyl, L represents hydrogen, (C1-C4)alkyl, (C1-C4)alkyoxy, phenyl, nitro, or halog...  
JPH08143508A
PURPOSE: To provide a method for easily producing a carboxylic acid derivative or its alkali metal salt useful as an intermediate for agricultural chemicals, medicines, etc. CONSTITUTION: An alcohol compound of formula I (R3 is lower alk...  
JPH0892157A
PURPOSE: To provide the subject novel compound that originates from a specific microorganism, has strong and selective inhibitory action against catecholamine- O-methyl transferase and is useful for the treatment of Parkinsonism. CONSTIT...  
JPH0838193A
PURPOSE: To effectively obtain optically active tetralin derivatives in an enzymatic process by hydrolyzing the specific racemic esters of tetralin derivatives with lipase to the specific yields, and subsequently inactivating the enzyme ...  
JPH082835B2  
JPH07330661A
PURPOSE: To produce the new dehydroabietic acid derivative capable of improving water and oil repellency, stain proofing properties, heat resistance, etc., therefore, useful as an additive for paper, rubber, ink, etc., having a biologica...  
JPH07116095B2
A process for preparing cyclohexanonecarboxylic acid compounds by catalytically hydrogenating the corresponding hydroxybenzoic acid compounds in a secondary alcohol or tertiary alcohol solvent.  
JPH07110830B2  
JPH07291857A
PURPOSE: To obtain a preventing and therapeutic agent for bone resorption osteopathy such as malignant hypercalcemia, bone Paget disease or osteoporosis containing a glycyrrhetinic acid compound as an active ingredient. CONSTITUTION: Thi...  
JPH07291858A
PURPOSE: To obtain a preventing and therapeutic agent for bone resorption osteopathy such as malignant hypercalcemia, bone Paget disease or osteoporosis containing a gypsogenin compound (salt) as an active ingredient. CONSTITUTION: This ...  
JPH07285909A
PURPOSE: To provide a new phenanthrene derivative having IL-1 inhibiting activity and useful for the treatment of chronic inflammatory diseases. CONSTITUTION: This phenanthrene derivative is a compound selected from the compounds of form...  
JPH07285905A
PURPOSE: To provide a method for selectively oxidizing a primary or secondary alcohol having an easily oxidizable group and a heterocycle to an aldehyde or ketone without changing the group and heterocycle. CONSTITUTION: An aldehyde or k...  
JPH07267895A
PURPOSE: To obtain a new compound useful as a therapeutic agent for diseases owing to leukotriene of pollinosis, bronchial asthma, arthritis, etc. CONSTITUTION: A compound of formula I (R1 is H or a 1-4C alkyl; R2 is H or methyl), e.g. a...  
JPH07258098A
PURPOSE: To obtain the subject inhibitor containing a ursonic acid expressed by a specific formula as active ingredients, having a marked inhibiting action of endothelin receptor binding and useful as a treating and preventing agent for ...  
JPH0780812B2  
JPH07188099A
PURPOSE: To efficiently obtain a cyclopentenone derivative useful as a synthetic intermediate for a thyrotropin-releasing hormone analogous compound, etc., in high yield by decarboxylating a cyclopentenone derivative prepared from a spec...  
JPH07188204A
PURPOSE: To safely and simply produce the subject compound in high efficiency by oxidizing a cyclic ketone having an alkoxy group on a carbon at α-position in the presence of a metal compound and an aldehyde using a safe and inexpensive...  
JPH07504675A
Novel cyclic anti-tumor promoter compounds and therapeutic compositions are disclosed, along with method for their production and use as anti-cancer and cancer-prevention agents.  

Matches 551 - 600 out of 1,014