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WO/2022/165511A1 |
Provided herein are tartaric acid analogs represented by the following structural formula: or a pharmaceutically acceptable salt thereof, wherein values for the variables (e.g., A, R) are as described herein. Compounds of structural form...
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WO/2022/165395A1 |
Stably consolidated compounds assembled from a statin and a metformin analog, and metabolically labile dual prodrugs assembled from the same, methods of making both, and methods of using them to treat metabolic diseases such as cancers a...
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WO/2022/163360A1 |
Provided is a method for producing a (meth)acrylic acid ester compound, the method making it possible to carry out esterification at a high introduction rate and to efficiently recover the resultant ester compound. The present inventio...
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WO/2022/155936A1 |
Disclosed in the present invention is a method for synthesizing an aryl benzyl ether compound, i.e., synthesizing a corresponding aryl benzyl ether compound by means of an oxidative coupling reaction of a phenolic compound and a toluene ...
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WO/2022/157370A1 |
The present invention relates to a continuous method for obtaining 2-ethylhexyl acrylate (2-EHA) from a liquid mixture (1) under an absolute pressure in the range from 0.5 to 100 bar which has a temperature in the range from 0 to 300°C,...
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WO/2022/157338A1 |
Method for the production of cannabinoid acid esters of general formula (I) or (II) or (III) or (IV), wherein R1 consists of a straight or branched alkyl group, alkenyl group or alkynyl group having from 1 to 5 carbons, during the simult...
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WO/2022/155932A1 |
Disclosed is an application of an iron (III) complex containing 1,3-di-tert-butyl imidazolium cation in synthesizing arylbenzyl ether compounds. Specifically, di-tert-butyl peroxide is used as an oxidant, and a corresponding arylbenzyl e...
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WO/2022/156624A1 |
Disclosed is a production process for producing a plasticizer from PTA oxidation residue. The production process comprises: S1, esterification, involving: adding PTA oxidation residue, octanol and a catalyst into an esterification reacto...
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WO/2022/156623A1 |
Disclosed is a comprehensive utilization process of PTA oxidation residue, the process comprising the following steps: S1, esterification; S2, rectification, involving: carrying out two-stage rectification on an esterification liquid, an...
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WO/2022/159855A1 |
Nanocarriers are engineered to realize the potential of RNA therapeutics. This work reports the design of photo-crosslinked bioreducible nanoparticles (XbNPs) for stable siRNA encapsulation in high serum conditions, shielded surface char...
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WO/2022/156543A1 |
Provided are a composite liquid antioxidant and a preparation method therefor. The composite liquid antioxidant comprises at least two antioxidants, and the antioxidants in the composite antioxidant each independently have the following ...
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WO/2022/155338A1 |
The present invention relates to a novel process for crystallizing high purity lutein and zeaxanthin esters from marigold oleoresin. In another aspect, the present invention relates to the removal of soft and hard waxes by adsorption on ...
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WO/2022/153003A1 |
The present invention relates to the field of perfumes and flavourings. More particularly, it relates to valencene derivatives and the use thereof as a perfuming or flavouring agent. It also relates to a perfuming or flavouring compositi...
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WO/2022/149357A1 |
The purpose of the present invention is to provide a specific method whereby it is possible to use a cyclic carbonate and an aliphatic monohydric alcohol as starting materials to industrially produce dialkyl carbonates and diols with hig...
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WO/2022/149462A1 |
A light-absorbing material according to one embodiment of the present disclosure includes a compound represented by formula (1) as a main component. In formula (1): R1 to R30 are independent of each other and include at least one element...
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WO/2022/150016A1 |
The present invention relates to processes for depolymerizing a polyester of a dicarboxylic acid and for hydrolyzing a diester of terephthalic acid in the presence of a first base and a solvent mixture into a mono-salt of a monoester of ...
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WO/2022/150761A1 |
The disclosure provides cosmetic compositions including cannabigerol (CBG), as well as methods of using the same for reducing skin redness, improving skin barrier functionality, brightening the skin of a subject, and enhancing the outwar...
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WO/2022/038365A9 |
The invention relates to compounds of formula (I) and to their use in treating or preventing an inflammatory disease or a disease associated with an undesirable immune response: wherein R, R1, R2 and RB are as defined herein.
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WO/2022/144728A1 |
Acrylic pressure-sensitive adhesive ("PSA") compositions crosslinked with a small-molecule crosslinker containing a single, thermally reversible moiety represented by the structure (I) (Formula I) ). wherein each R1 is independently -H o...
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WO/2022/147047A1 |
The present application discloses, in part, isolated, stable and biologically active menaquinol derivatives and their methods of use for the treatment of various diseases.
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WO/2022/145617A1 |
Provided is a pharmaceutical composition for cardiovascular treatment comprising a potassium all-trans retinoate compound and a potassium 9-cis retinoate compound. It has confirmed that the pharmaceutical composition is metabolically sta...
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WO/2022/142159A1 |
Disclosed is a preparation method for icetexane type abietane diterpene, comprising the following steps: S1: adding carnosic acid into a methylation system, carrying out solid-liquid separation, and collecting a solid phase to obtain an ...
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WO/2022/136232A1 |
There is provided a method for preparing homofarnesol (1), the method comprising the steps of: a) providing farnesyl chloride (2); b) reacting farnesyl chloride (2) to homofarnesate (3) by alkoxycarbonylation; and c) reacting homofarnesa...
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WO/2022/139288A1 |
The present invention relates to a process for hydrogenation of a phthalate compound. According to the present invention, following the hydrogenation of a phthalate compound, a reaction product can be stably decompressed to isolate and r...
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WO/2022/134287A1 |
The present invention relates to a method for preparing a carboxylic acid ester compound. Under the catalysis of nitrite, an carboxylic acid reacts with an alcohol in air so as to obtain an ester compound; and the alcohol is ethanol, pro...
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WO/2022/138511A1 |
This production method of a fluorine-containing polyether compound involves producing the compound of formula (3) by reacting the compound of expression (1) and the compound of expression (2) in a ratio such that the compound of formula ...
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WO/2022/138670A1 |
Provided are a compound, polymer, composition, film-forming composition, pattern formation method, method for forming insulating films, and compound production method, that yield a resist that exhibits excellent exposure sensitivity. T...
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WO/2022/138915A1 |
Provided is a refined rosmarinic acid-containing composition production method that enables obtaining of a highly transparent aqueous solution by reducing the amount of luteolin while causing rosmarinic acid to remain. This refined ros...
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WO/2022/138748A1 |
The present invention provides a labeling method that comprises a step for labeling a substrate, which has a carbon-hydrogen bond, with an oxygen isotope with use of a catalyst and an oxidant that is produced from a hypervalent iodine co...
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WO/2022/136227A1 |
There is provided a method for preparing homofarnesol (1), the method comprising the steps of: a) providing homofarnesylnitrile (2); b) reacting homofarnesylnitrile (2) to homofarnesic acid (3); and c) reacting homofarnesic acid (3) to h...
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WO/2022/133586A1 |
Metformin prevents hyperglycaemia-associated, oxidative stress-induced vascular endothelial dysfunction at low concentrations (~1 µM). The orphan nuclear receptor Nr4al (i.e. Nur77) is involved in the protective activity, which can be r...
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WO/2022/137144A1 |
Provided is a composition comprising an ester derived from at least one acid form of a cannabinoid (such as one selected from the group consisting of cannabigerolic acid (CBGA), tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBD...
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WO/2022/134297A1 |
The present invention relates to a preparation method for a carboxylate ester compound, comprising: under the catalysis of a nitrite ester, reacting carboxylic acid and methanol in air, so as to obtain an ester compound. The preparation ...
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WO/2022/138635A1 |
[Problem] To provide an internal donor component capable of producing, with high productivity, a propylene polymer having extremely high stereoregularity when used mainly as a solid titanium catalyst component. [Solution] A polyol ester ...
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WO/2022/140458A1 |
Provided are compounds that are suitable for cryopreservation of cells. The compounds are non-toxic, water soluble, and free of any organic solvents. The compounds have the following structure: Formula (I), where n is 1, 2, 3, or 4 and e...
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WO/2022/126268A1 |
The disclosure relates to a compound of formula wherein Y, X, Ra, Rb, R1 and R2 are defined herein, PVC compositions comprising the compounds disclosed herein, as well as methods for modulating properties of a PVC, including reducing or ...
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WO/2022/131378A1 |
A novel method for producing a fluorinated organic compound is provided. The method for producing a fluorinated organic compound comprises a step in which a compound represented by formula (1) (wherein R1 and R2 are each independently a ...
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WO/2022/131970A1 |
The invention relates to the field of creating simulators of the scent of narcotic and psychotropic substances for use in training detection dogs to detect narcotic and psychotropic substances. A liquid simulator contains an aromatic add...
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WO/2022/122836A1 |
Disclosed is the use of certain methyl-fluoro-hydroxybenzoates as flavor and fragrance constituents and for imparting a wintergreen odor note to a consumer product. Furthermore the use of certain methyl-fluoro-hydroxybenzoates as complet...
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WO/2022/122975A1 |
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as a drug, especially as an antibiotic. The present invention also relates to a pharmaceutical composition c...
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WO/2022/120478A1 |
There is provided a method for producing hydrogel microparticles with spherical shape and having a narrow-disperse or mono-disperse size distribution. At least one temporary crosslinker such as those of formula (I), (Ila)- (Ilf) and at l...
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WO/2022/124182A1 |
The present invention provides a method for producing a fluorine-containing polymer, said method being suppressed in variation in the weight average molecular weight among production lots. A method for producing a fluorine-containing pol...
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WO/2022/121317A1 |
Disclosed is a 1,1'-biphenyl-2,6-diphenolic compound and the use thereof. The 1,1'-biphenyl-2,6-diphenolic compound is a new compound, and has good biological activity. By means of in vitro tumor cell activity experiments, it was found t...
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WO/2022/119070A1 |
The present invention relates to a catalyst system for preparing a carbonate derivative, comprising selenium (Se) and a pyridine amine compound represented by structural formula 1. The catalyst system for preparing a carbonate derivative...
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WO/2022/118959A1 |
The problem addressed by the present invention is to provide a compound used in the formation of an optically anisotropic film that excels in a reverse wavelength dispersion property and a heat-and-moisture durability property, a polymer...
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WO/2022/119792A1 |
Disclosed is a process for preparing 2,2,4,4-tetramethylcyclobutane- 1,3-diol by reacting 2,2,4,4-tetramethylcyclobutanedione with isobutanol in the presence of a tandem transfer hydrogenation and Tischenko reaction catalyst.
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WO/2022/119706A1 |
A process for preparing aldehydes from methanol includes introducing a feed stream comprising methanol and hydrogen gas into a reaction zone of a first reactor, converting the feed stream into an intermediate stream comprising C2 to C4 o...
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WO/2022/118951A1 |
The present invention addresses the problem of providing: a compound to be used in forming an optically anisotropic film having excellent reverse wavelength dispersion properties; a polymerizable composition; an optically anisotropic fil...
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WO/2022/115400A1 |
Provided herein are processes for synthesizing intermediates useful in preparing Mcl-1 inhibitors. In particular, provided herein are processes for synthesizing compound IA, wherein R1 is described herein. Compound IA can be useful in sy...
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WO/2022/114577A1 |
The present invention relates to a method for producing heterogeneous linear carbonates, comprising a step in which transesterification of dimethyl carbonate (DMC) and Ethanol (EtOH) is carried out in the presence of a catalyst, the cata...
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