Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 18,464

Document Document Title
WO/2022/168755A1
The present invention provides a nonaqueous electrolyte solution comprising: (I) at least one compound selected from the group consisting of compounds represented by general formula (1) in the description (for example, compounds represen...  
WO/2022/166747A1
The present invention relates to an amino lipid compound, namely a compound represented by chemical formula I, or a stereoisomer, tautomer, pharmaceutically acceptable salt or prodrug thereof. Moreover, also disclosed are a preparation m...  
WO/2022/168884A1
The present invention provides a novel cationic lipid having excellent encapsulation and delivery stability of nucleic acid medicines. Provided is a compound represented by formula (I) or a pharmacologically acceptable salt thereof. (In ...  
WO/2022/169747A1
There is disclosed a method for preparing levetiracetam and intermediates from a compound of the formula: (I) wherein CR is selected from the group consisting of cyano, carboxylic acid, carboxamide, alkali carboxyl ate, alkaline earth me...  
WO/2022/167866A1
The present disclosure relates in part to chemical modulators of protein phosphatase 2A (PP2A), comprising formula (I). The compounds of the present disclosure are useful in treating, preventing, and/or ameliorating cancer, diabetes, aut...  
WO/2022/167867A1
The present disclosure relates in part to chemical modulators of protein phosphatase 2A (PP2A). The compounds of the present disclosure are useful in treating, preventing, and/or ameliorating cancer, diabetes, autoimmune disease, solid o...  
WO/2022/162992A1
The present invention addresses the problem of providing a new pharmaceutical composition that can treat a T cell-independent reaction or an early phase reaction (a symptom in an early phase) of an allergic disease. Examples of the pre...  
WO/2022/162153A1
The present invention relates to novel conjugated oligonucleotide compounds, which are suitable for therapeutic use. Additionally, the present invention provides methods of making these compounds, as well as methods of using such compoun...  
WO/2022/160530A1
The present invention provides an anisomycin derivative represented by a general formula (I) or a pharmaceutically acceptable salt, solvate, and stereoisomer thereof. In the present invention, it is found that the anisomycin and derivati...  
WO/2022/162157A1
The present invention relates to novel conjugated oligonucleotide compounds, which are suitable for therapeutic use. Additionally, the present invention provides methods of making these compounds, as well as methods of using such compoun...  
WO/2022/164041A1
The present invention relates to a novel compound exhibiting anti-inflammatory activity, and the compound of the present invention plays a key role in the generation of pro-inflammatory cytokines, thereby having excellent inhibitory acti...  
WO/2022/159980A1
Disclosed herein are compounds (e.g., pyrrole compounds, carboxy pyrroles, etc.), including pharmaceutical compositions that include one or more of such compounds (e.g., carboxy pyrroles). Also disclosed are methods of making carboxy pyr...  
WO/2022/159955A1
The present disclosure relates to compounds, and to their pharmaceutical compositions, that inhibit dipeptidyl peptidase IV (DPP4). The compounds selectively promote the proliferation of alveolar type 2 cells (AEC2s) and are useful in th...  
WO/2022/156758A1
A novel amide pyrrole compound and a use thereof in drugs, in particular, a use thereof as drugs for treating and/or preventing hepatitis B virus infections or diseases caused by the hepatitis B virus infections. Specifically, the presen...  
WO/2022/156827A1
The present invention relates to an allicin derivative, having the structure as shown in formula I, and a preparation method and use therefor, wherein R1 and R2 are respectively an alkyl group having 1 to 4 carbons, a cycloalkyl group, a...  
WO/2022/158993A1
The present invention relates to a method for the production of d-erythro-sphingosine and analogs thereof, wherein the method comprises a step of condensing a compound of formula (2): Formula (2), or a salt thereof, wherein R1 is hydroge...  
WO/2022/156693A1
A compound represented by formula I containing an N-(substituted sulfonyl) acetamide structure, a pharmaceutically acceptable salt, isomer, hydrate or solvate thereof, and an application thereof as a viral protease inhibitor in the prepa...  
WO/2022/159649A1
The present invention is related to the development of novel compounds and methods for the treatment and/or prevention of malaria. The compounds prevent the formation by the malaria parasite of the piasmodium surface anion channel (PSAC)...  
WO/2022/153626A1
Provided is a simple method for manufacturing a heterocycle-containing amino acid compound. This heterocycle-containing amino acid compound is manufactured by a method including a step A wherein a compound represented by the formula (2) ...  
WO/2022/145923A1
The present invention relates to a pharmaceutical composition which is for preventing or treating viral infections and contains a piperlongumine-based compound as an active ingredient. Specifically, the piperlongumine-based compound acco...  
WO/2022/143610A1
Disclosed are novel amide pyrrole compounds and the use thereof in medicaments, especially the use thereof as a medicament for treating and preventing hepatitis B. In particular, the present invention relates to a compound as represented...  
WO/2022/145707A1
The present invention provides a novel piperlongumine-based compound, and an immunomodulator and a health functional food for immunomodulation, which comprise the compound or a pharmaceutically acceptable salt or solvate thereof as an ac...  
WO/2022/134260A1
A preparation method for biliverdin or a derivative thereof. Biliverdin or the derivative thereof is prepared from a compound represented by formula 2. Formula II represents a single bond or a double bond. Formula II at the positions rep...  
WO/2022/139593A1
Method for the preparation of amidines of formula (I) or formula (II) Formula (I), Formula (II), in a one-pot reaction process, from amines and carboxylic acid derivatives, where neither the use of a solvent nor the use of a metal comple...  
WO/2022/134261A1
A biliverdin compound, having a structural formula as shown in formula 1, wherein R is selected from one of hydrogen, C1-C5 alkyl, and benzyl. Formula II represents a double bond or a single bond, and said formulas II in positions A and ...  
WO/2022/137913A1
The present invention provides: a maleimide resin and a maleimide compound which are characterized by being a product of maleimidization of a polyamine compound (C) which is a product of reaction between a plurality of aromatic monoamine...  
WO/2022/138944A1
The present disclosure provides a pharmaceutical composition for treating and/or preventing SWI/SNF complex-dysfunction cancer. More specifically, according to the present disclosure, a compound represented by formulae (1) to (23) (the f...  
WO/2022/133551A1
The present application is directed towards compounds, pharmaceutically acceptable salts or prodrugs thereof, which are inhibitors of Histone Deacetylase (HDAC) binding or function. The compounds especially may have some selectivity for ...  
WO/2022/134262A1
Provided is a dipyrromethene-1-one compound having a structural formula as represented by formula 1, wherein R is selected from one of hydrogen, C1-C5 alkyl and benzyl; R1 is selected from one of phenylthio, phenylsulfinyl, phenylsulfony...  
WO/2022/138791A1
The purpose of the present invention is to provide a medicine for the prevention and/or treatment of a disease caused by activation of an EP2 receptor, said medicine containing, as an active ingredient, a compound having an antagonistic ...  
WO/2022/134259A1
The present invention provides a pyrrolinone compound of which the structural formula is as shown in formula 1. R1 is selected from one of: C1-C5 alkoxy groups, a benzyloxy group, C1-C5 alkyl groups, and a phenyl group; R2 and R3 are eac...  
WO/2022/139594A1
Method for the preparation of two amides from one amidine in a one-pot conversion, where amides of formula (I) or formula (II) are formed. Formula (Ia) and Formula (Ib) Fornula (IIa) and Formula (IIb).Obtained amides and their useful app...  
WO/2022/140269A1
Materials, methods, and systems for biorthogonal ligation of hydrogel labels to crosslinked-natural polymer hydrogels are provided. A heterobifunctional linker includes a peptide-reactive activated functional group on the heterobifunctio...  
WO/2022/133040A1
Provided are kinases inhibitors, pharmaceutical compositions comprising such compounds, and methods of using such compounds or compositions, such as methods of treating a proliferation disorder, such as a cancer or a tumor, or in some em...  
WO/2022/129327A1
The present invention relates to compounds having a structure of general formula (I), processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in ...  
WO/2022/130411A1
The present invention relates to novel SMAC mimetic peptidomimetics useful for the treatment of proliferative diseases including cancer in mammals. The novel SMAC mimetics are prepared by incorporating (2S,5R)-5-(5-methylfuran-2-yl)pyrro...  
WO/2022/133097A1
The disclosure provides processes for preparing spiro derivatives, in particular (2R,5S)-7-methyl-2-[4-methyl-6-[4-(trifluoromethyl)-phenyl]p yrimidin-2-yl]-1,7- diazaspiro[4.4]nonan-6-one, as well as intermediates for use in said proces...  
WO/2022/129047A2
The present invention is directed to novel modulators of the NMDA receptor. Separate aspects of the inventions are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat neurological disorder...  
WO/2022/132650A1
Described herein is a prodrug of a transient receptor potential vanilloid 1 receptor (TRPV1) agonist for the treatment of pain.  
WO/2022/129953A1
P33613WO1 93 ABSTRACT The disclosures herein relate to compounds of Formula (1'): or a salt thereof, wherein A, Q, X, Z, L, R2, R3 and R9 are defined herein, and their use in the treatment of SARS-CoV-2 and related viruses and disorders ...  
WO/2022/132649A1
Provided herein are pharmaceutical formulations comprising a transient receptor potential vanilloid 1 receptor (TRPV1) agonist, or a pharmaceutically acceptable salt thereof.  
WO/2022/131364A1
Provided is a wavelength conversion member that comprises a wavelength conversion layer and a base member, wherein the wavelength conversion layer contains a pyrromethene derivative and at least one inorganic phosphor selected from the g...  
WO/2022/121661A1
Disclosed in the present invention is an organic acid lithium amino acid salt. The organic acid lithium is one or more of lithium isobutyrate, lithium n-butyrate, lithium lactate, lithium citrate or lithium cholesterol; the amino acid is...  
WO/2022/121317A1
Disclosed is a 1,1'-biphenyl-2,6-diphenolic compound and the use thereof. The 1,1'-biphenyl-2,6-diphenolic compound is a new compound, and has good biological activity. By means of in vitro tumor cell activity experiments, it was found t...  
WO/2022/119090A1
The present invention relates to a compound, or pharmaceutically acceptable salts thereof, for inhibiting the activity of the 5-HT7 serotonin receptor represented by structural formula 1 or 2.  
WO/2022/087422A9
The present disclosure relates to compounds of Formula (I'): and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are use...  
WO/2022/047128A9
The present disclosure provides methods and compositions useful for diagnosing and treating activated alternative pathway of complement in a human subject with a SARS-CoV-2 infection. Also provided are methods of treating an infection by...  
WO/2022/112351A1
The present invention relates to malonamide compounds of the formula (I) wherein the variables are as defined in the claims and the description, and to compositions comprising these compounds. The invention also relates to the use of sai...  
WO/2022/110842A1
Disclosed are a crystal form A of levorotatory fluoropyrrolidone and a preparation method therefor. In a powder X-ray diffraction pattern of the crystal form A, the crystal form A has a characteristic peak at a diffraction angle 2θ, whe...  
WO/2022/110916A1
A method for preparing a nitrogen-containing heterocyclic compound and a derivative thereof by means of an enzymatic-chemical cascade method, comprising: reacting an alcohol, an amine, an alcohol dehydrogenase, a flavin molecule and a co...  

Matches 1 - 50 out of 18,464