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Matches 1 - 50 out of 6,657

Document Document Title
WO/2021/066873A1
The disclosure includes compounds of Formula (A) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, and R11, h, j, m, n, k, v, s, g, V, W, L, Z1 Q1, Q2, Q3, Q4, Q5, Q6, and Q7, are defined herein. Also disclosed is a method for treating a ...  
WO/2021/067335A1
The present invention provides compounds and pharmaceutical compositions including the compounds for the treatment of a skin disease associated with proteolytic activity of one or more KLK proteases, wherein the compounds are according t...  
WO/2021/058021A1
A drug combination containing a TLR7 agonist. Specifically, a drug combination jointly using the compound of formula I acting as a TLR7 agonist and entecavir for the treatment of hepatitis B virus infection and a use thereof, the drug co...  
WO/2021/055630A1
The invention provides substituted, saturated and unsaturated N-heterocyclic carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical...  
WO/2021/050583A1
Embodiments of the disclosure include methods and compositions for treating neurological disorders by stimulating regenerative and anti-inflammatory activity of fibroblasts. In specific embodiments, fibroblasts are administered to an ind...  
WO/2021/007661A1
The current application relates to cannabinoid derivatives of formula (I) and pharmaceutical compositions comprising the same. The cannabinoid derivative can be used for the treatment of diseases associated with cannabinoid receptor such...  
WO/2021/000434A1
Disclosed are a red, green and blue thermally activated delayed fluorescent material, a synthesis method therefor and use thereof. The red, green and blue thermally activated delayed fluorescent material has a general formula (I). The di...  
WO/2020/260418A1
A method is provided for preparing a compound ƒ. The method comprises carrying out the following reaction: (i), (ii), (iii) where: PG represents a protecting group, LG represents a leaving group, and L and L' are independently selected ...  
WO/2020/106642A8
The present disclosure relates generally to compounds and pharmaceutical compositions suitable as modulators of hemoglobin, and methods for their use in treating disorders mediated by hemoglobin.  
WO/2020/263484A1
This document relates to methods and materials for treating a neuromyelitis optica (NMO) spectrum disorder such as NMO. For example, one or more tetracycline antibiotics can be administered to a mammal having, or at risk of developing, a...  
WO/2020/260417A1
A method is provided for preparing a compound / the method comprising carrying out the following reaction: Formula (i); Formula (ii) where: R10 is hydrogen or a hydroxy protecting group; PG is an amine protecting group; and q is 1 where ...  
WO/2020/258525A1
Provided in the present application is an electroluminescent material, a preparation method for an electroluminescent material, and a luminescent device. In the electroluminescent material, an asymmetric monocyanopyrazine of a pyrene nuc...  
WO/2020/249759A1
The invention discloses a method for fluoroalkylation of enamines with a fluoro alkyl halide in the presence of a base.  
WO/2020/234245A1
The invention discloses a method for preparation of Carsalam by a reaction of salicylamide with diethyl carbonate in the presence of an alkali ethoxide.  
WO/2020/223536A1
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.  
WO/2020/223538A1
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.  
WO/2020/211124A1
The present invention relates to a thermally activated delayed fluorescence material, a preparation method therefor, and an organic light-emitting diode device. The structural general formula of the thermally activated delayed fluorescen...  
WO/2020/211121A1
The present invention relates to a thermally activated delayed fluorescence material, a preparation method therefor, and an organic electroluminescent diode device, the structural general formula of the thermally activated delayed fluore...  
WO/2020/200291A1
This disclosure relates to heterobifunctional compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the heterobifunctional compounds, and to methods of use the heterobifunctional compounds for t...  
WO/2020/205765A1
The present invention provides photocatalysts, methods for their preparation, and methods for preparing linear polymers with high propagation rate.  
WO/2020/199945A1
The present invention relates to the technical field of medicine, and discloses a compound as shown in formula (I) and a preparation method therefor, a pharmaceutical composition and the use thereof. In particular, further disclosed in t...  
WO/2020/195576A1
Provided is a novel method for producing a hemiaminal compound, and a method for producing a heterocyclic compound. In this method for producing a hemiaminal compound, a compound represented by formula (1), a compound represented by form...  
WO/2020/191866A1
A thermally activated delayed fluorescent material having a chemical structural formula (A), the R group being a diphenylamine group. An efficient deep blue thermally activated delayed fluorescent material is produced by using tetrastyre...  
WO/2020/193419A1
The present invention relates to novel compounds, pharmaceutical compositions comprising such compounds and their use for treating, alleviating or preventing diseases or disorders relating to the activity of potassium channels.  
WO/2020/188183A1
The invention relates to a process for producing a polybenzoxazine monomer, the crosslinking thereof, and the use of the crosslinked product to form ablative thermal protection for a propelling nozzle or a body for atmospheric re-entry.  
WO/2020/188182A1
The invention relates to a process for producing a polybenzoxazine monomer, the crosslinking thereof and the use of the crosslinked product to form an ablative thermal protection for a thruster nozzle or an atmospheric re-entry body.  
WO/2020/176501A1
The disclosure provides compounds of Formula I (Formula I) (c) And the pharmaceutically acceptable salts thereof. The A, B, C, and D rings and the variables, RA, RB, RC, RD, L0, L1, L2, and L2, are defined herein. Compounds and salts of ...  
WO/2020/170080A1
A hydrofluoroolefin compound is represented by the following general formula (I): where RF1 is a hydrogen atom or CH3, and (iii) RF1 is a linear or branched perfluorinated alkyl group having 1 to 10 carbon atoms and optionally including ...  
WO/2020/163464A1
A curable composition, a method of making the curable composition, and an article and product produced therefrom are provided. A morpholinedione is contacted with an isocyanate to form a resin composition. The resin composition is reacte...  
WO/2020/152037A1
A radiation curable inkjet ink containing at least one or two compounds selected from the group consisting of a polymerizable compound including a vinylether group or a vinylamide group, an amine synergist including an alkanolamine group...  
WO/2020/145250A1
[Problem] To provide a compound having a 15-PGDH inhibitory effect. [Solution] A compound represented by general formula (1) or a pharmacologically acceptable salt thereof.  
WO/2020/076274A3
The present invention is related to unique caffeic acid phenethyl ester (CAPE) analogues, methods for preparation of said molecules, and the usage of said unique molecules in the preparation of a pharmaceutical composition that is to be ...  
WO/2019/090085A8
Provided herein are compounds of formula (I), compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions. (Formula I).  
WO/2020/127319A1
The present invention relates to the combination of sulfonamide derivatives which are ABA agonists and at least one additional active ingredient selected from the group consisting of fungicides/bactericides, insecticides/acaricides and a...  
WO/2020/127386A1
A method is provided for preparing an intermediate d having the formula: (I). The method comprising carrying out the following one-pot reaction: (II) wherein step (i) is carried out in the presence of a solvent and step (ii) is carried o...  
WO/2020/127390A1
A method is provided for preparing a compound d having the formula (D) The method comprises carrying out the following reaction (c) → (d), where the reaction is carried out at a temperature of at least 100 °C and in the presence of a ...  
WO/2020/124771A1
The present invention relates to a thermally activated delayed fluorescent compound, a preparation method therefor and an organic electroluminescent diode device thereof. The thermally activated delayed fluorescent compound has a structu...  
WO/2020/127385A1
A method is provided for preparing a compound d having the formula: Formula (I). The method comprises carrying out the following reaction: Formula (i), (ii), (d) where: step (i) is carried out in the presence of a metal catalyst and a hy...  
WO/2020/106642A1
The present disclosure relates generally to compounds and pharmaceutical compositions suitable as modulators of hemoglobin, and methods for their use in treating disorders mediated by hemoglobin.  
WO/2020/098114A1
Disclosed are a thermally activated delayed green light fluorescent material, a synthesis method thereof, and an electroluminescent device comprising same. The thermally activated delayed green light fluorescent material is a target comp...  
WO/2020/094528A1
The present invention relates to novel processes for the enantioselective iridium-catalysed hydrogenation of oximes and oxime ethers to provide compounds of formula (II) and salts thereof formula (I) and (II).  
WO/2020/092383A1
The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processe...  
WO/2020/082601A1
Disclosed are a dark red photothermally activated delayed fluorescence material, a synthesis method therefor and an electroluminescent device. The dark red photothermally activated delayed fluorescence material is a target compound, whic...  
WO/2020/081836A1
The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.  
WO/2020/077884A1
Provided are an electroluminescent material, a method for preparing an electroluminescent material, and a light emitting device. The preparation method comprises: using a reaction between 2,7-dibromofluorene and bromohexyl to generate a ...  
WO/2020/072377A1
The present disclosure relates to compounds of the general formula (I) and pharmaceutical compositions containing them. The compounds are suitable as modulators of hemoglobin and thus useful in treating disorders mediated by hemoglobin s...  
WO/2020/054218A1
A purpose of the present invention is to provide a benzoxazine compound usable in a curable resin composition which has excellent pliability before curing and has excellent dielectric properties after curing. Another purpose of the prese...  
WO/2020/046335A1
Compounds and pharmaceutically acceptable salts thereof of Formula I are disclosed. Certain compounds and salts of Formula I are active as CMA modulators. The disclosure provides pharmaceutical compositions containing a compound of Formu...  
WO/2020/045856A1
The present invention relates to a novel hypoxia-inducible factor 1α (HIF-1α) inhibitor, a preparation method therefor, and a pharmaceutical composition for preventing or treating angiogenesis-associated eye disease, containing same as...  
WO/2020/039094A1
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haemat...  

Matches 1 - 50 out of 6,657