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Matches 301 - 350 out of 941

Document Document Title
WO/1996/013260A1
A compound having formula (I) wherein Me represents a methyl group, having an antibacterial activity.  
WO/1996/006087A1
This invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, which are effective for inhibiting platelet aggregation and bone resorption, pharmaceutical compositions for effecting such activity, and a...  
WO/1996/005185A1
The present invention relates to novel alkylamino derivatives of formula (I). These compounds exhibit a high selectivity and a high affinity for sigma 2 receptor and therefore are useful in the treatment of central nervous system disorde...  
WO/1996/003966A1
A hair styling and conditioning process comprising the steps of: contacting the hair with a compound having an electrophilic group and at least one hydrophobic group whereby the electrophilic group reacts with nucleophilic sites on and i...  
WO/1995/033733A1
The present invention provides substituted dibenzoxazepine and dibenzothiazepine compounds of Formula (I), which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective...  
WO/1995/033734A1
The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula (I) which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective a...  
WO/1995/021833A1
Substituted oxazacycloalkenes of formula (I) in which A is optionally substituted alkane diyl (alkylene), Ar is optionally substituted arylene or heteroarylene; E is a 1-alkene-1,1-diyl group containing a radical R1 in the 2nd position o...  
WO/1995/021834A1
Disclosed is an optically active 4,1-benzoxazepin-2-one derivative of formula (I), wherein R1 represents a lower alkyl group; X represents a hydrogen atom or a metal ion; ring A represents a phenyl group substituted with halogen; ring B ...  
WO/1995/018972A1
A method for obtaining compounds having selected properties for a particular application by forming base modules having at least two structural diversity elements from the reaction of a first compound having at least one structural diver...  
WO/1995/018104A1
A novel benzamide derivative represented by general formula (I), or a salt, hydrate or solvate thereof. The compound is useful as a 5-HT4 receptor agonist for preventing and treating central nervous system diseases such as schizophrenia,...  
WO/1995/004534A1
Novel compounds are described which are endothelin receptor antagonists.  
WO/1995/003279A1
Novel antitumor sulfonamide and sulfonic ester derivatives each having a tricyclic hetero ring, represented by general formula (I), and a process for producing the same, wherein G represents a 5- or 6-membered aromatic ring; L represents...  
WO/1995/003289A1
There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production...  
WO/1994/029286A1
The present invention provides substituted dibenzoxazepine and dibenzothiazepine compounds of formula (I) which are useful as analgesic agents for the treatment of pain, and for prostaglandin-E2 mediated diseases, pharmaceutical composit...  
WO/1994/028901A1
An amino acid derivative having an angiotensin I-converting enzyme inhibitor activity, a vasopressin antagonism and an atrial natriuretic peptide hydrolase inhibitor activity, and represented by general formula (I) wherein R1 represents ...  
WO/1994/027981A1
The present invention provides substituted dibenzoxazepine compounds of formula (I) which are useful as analgesic agents for the treatment of pain, and as prostaglandin-E2 antagonists for the treatment of prostaglandin-E2 mediated diseas...  
WO/1994/026719A1
This invention relates to new mercapto-amide derivatives possessing inhibitory activities against the neutral endopeptidase and the angiotensin converting enzyme, and represented by general formula (I), wherein R1 is hydrogen or a mercap...  
WO/1994/022840A1
This invention relates to novel substituted caprolactams, including 4-azacaprolactams such as those of formula (Ic) in which R4, R7, R22, and R27 are as defined in the description, and derivatives thereof which inhibit HIV protease and a...  
WO/1994/019329A1
This invention relates to substituted cyclic carbonyls and derivatives thereof useful as Human Immnunodeficiency Virus (HIV) protease inhibitors, to pharmaceutical compositions comprising such compounds, and to methods of using these com...  
WO/1994/014776A2
This invention relates to compounds of formulae (I), (II), (II), wherein A1 is O, S, N-R1 or CHR1; A4 is N-R4 or CHR4; R2 is a sidechain containing an acid or ester group; R1, R4 and R5 are substituents such as H, alkyl and aryl alkyl, a...  
WO/1994/013651A1
The invention concerns substituted 3-amino-1-arylalkylbenzazepin-2-ones of general formula (I), in which Ar is aryl; X is -O- or -S(O)n- and n is 0, 1 or 2; X1 is C1-C2 alkylene or a single bond; R1 is hydrogen, lower alkyl, aryl(lower a...  
WO/1994/008977A1
This invention relates to novel substituted caprolactams of formula (I), including 4-azacaprolactams, and derivatives thereof which inhibit HIV protease and are useful for treatment of HIV disease. Also included in this invention are pha...  
WO/1994/007483A1
There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production...  
WO/1994/005634A1
There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production...  
WO/1994/004518A1
Compounds characterized generally as morpholino/thiomorpholino-terminated alkylamino ethynyl alanine amino diol derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of f...  
WO/1994/001421A1
The present invention relates to novel substituted benzothiazepines and benzoxazepines of formula (I), wherein R1, R2, R7, R8, R9 and X are as defined below, and to novel intermediates used in the synthesis of such compounds. Such compou...  
WO/1993/019045A1
Substituted amides, agricultural compositions containing them and a method to control arthropods in agronomic and nonagronomic environments, the amides having formula (I) wherein X is oxygen or sulfur and Q, G and Y are as defined in the...  
WO/1993/019046A1
A series of non-peptide derivatives that are antagonists of the fibrinogen IIb/IIIa receptor and thus are platelet anti-aggregation compounds useful in the prevention and treatment of diseases caused by thrombus formation.  
WO/1993/013082A1
The present invention provides substituted dibenzoxazepine compounds of formula (I) which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound o...  
WO/1993/009105A1
The present invention provides substituted dibenzoxazepine compounds of formula (I) which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound o...  
WO/1993/009104A1
The present invention provides substituted dibenzoxazepine compounds of formula (I), which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound ...  
WO/1993/008174A1
A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII¿b?III¿a? receptor and is provided in therapeutic compositions for ...  
WO/1993/007128A1
This invention relates to substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors, to pharmaceutical compositions comprising such compounds, and to methods of using these compounds for treating viral...  
WO/1993/007132A1
The present invention provides substituted dibenzoxazepine compounds of formula (I), which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound ...  
WO/1993/003372A1
Immunoassay methods and reagents for the quantification of total doxepins (i.e., E-doxepin, Z-doxepin, E-desmethyldoxepin, and Z-desmethyldoxepin) in a test sample are disclosed. The quantification of total doxepins is accomplished in an...  
WO/1993/000095A2
This invention relates to compounds of formula (I), wherein A1 to A5 form an accessible substituted seven-membered ring, which may be saturated or unsaturated, optionally containing up to two heteroatoms chosen from the group of O, S and...  
WO/1992/019605A1
The present invention provides substituted dibenzoxazepine compounds of formula (I) which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound o...  
WO/1992/019617A2
The present invention provides dibenzoxazepine compounds of formula (I) which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of formula (I...  
WO/1992/016524A1
There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production...  
WO/1992/012133A2
Compounds of formula (I), wherein Q, X, R?1�, R?2�, R?9� and Z are as defined in the text, including compositions containing said compounds and a method for using them to control arthropods.  
WO/1991/010645A2
There are provided novel chelating agents useful in the preparation of contrast media for diagnostic imaging or of radiotherapeutic or detoxification compositions.  
WO/1991/007394A1
Novel, substitued benzoxazines of the structure compounds of formula (I) wherein: X and Y are independently selected from the group consisting of: hydrogen, C1-6 alkyl, C1-6 alkyoxy C1-6 alkyl, C1-6 aminoalkyl, C1-6 hydroxyalkyl, and C1-...  
WO/1991/005549A1
Novel benzoheterocyclic compounds of formula (I), wherein R?1¿ is H, halogen, alkyl, optionally substituted amino, alkoxy; R?2¿ is H, halogen, alkoxy, phenylalkoxy, OH, alkyl, optionally substituted amino, carbamoyl-alkoxy, optionally ...  
WO/1991/000273A1
Cyclic anthranilic acid derivatives of general formula (I) and acid addition salts and alkali salts thereof, useful for treating rheumatism, autoimmune diseases and metabolic bone diseases, wherein R1, R2 and R3 may be the same of differ...  
WO/1990/007111A2
A molecular model of the interaction of various non beta-lactam antibiotics with the active site of a penicillin receptor has been developed so that it is now possible to predict the ''fit'' and ''reactivity'' of potential antibacterial ...  
WO/1990/000407A1
Methods for treating animals comprising applying to the animal's dermis or membrane physiologically active compounds in intimate mixture with an effective amount of penetration enhancers having formula (I) are disclosed, where R=H, alkyl...  
WO/1989/008643A1
The invention relates to urethane-protected amino acid-N-carboxyanhydride and N-thiocarboxyanhydride compounds which are useful in peptide, polypeptide, and protein synthesis. Disclosed herein is the preparation and use of these novel co...  
WO/1989/007640A1
The present invention relates to a detergent composition in aqueous solution comprising, (i) a surfactant selected from anionic, nonionic, zwitterionic and cationic surfactants and mixtures thereof, (ii) a precursor compound capable of g...  
WO/1988/008424A1
The aromatic amines (I), alkyl amines (II), bicyclic amines (III), cycloalkyl amines (IV), aromatic bicyclic amines (V), hydroquinone amines (VI), quinone amines (VII), amino-ethers (VIII) and bicyclic amino ethers (IX) are useful as pha...  
WO/1987/006226A2
An azacycloalkane derivative useful for promoting the absorption of a medicine, an absorption promoting agent comprising at least one of the azacycloalkane derivatives as the effective ingredient for promoting the absorption and an exter...  

Matches 301 - 350 out of 941