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WO/2018/057056A1 |
A high heat epoxy composition including a high heat epoxy compound; and an auxiliary epoxy compound different from the high heat epoxy compound; wherein the composition has a glass transition temperature between -10°C and 62°C, prefera...
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WO/2018/051237A1 |
The present invention relates to a process for the purification of compound of formula II, wherein X may be independently selected from trifluoroacetic acid, hydrochloric acid, hydrobromic acid, p-toluene sulfonic acid and phosphoric aci...
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WO/2018/046684A1 |
Described is a process as well as intermediates for the preparation of compound of the general formula (I); especially of formula (la) in which the substituents R1, R2, R3, R4 and R5 have the meaning indicated in the present specification.
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WO/2018/038505A1 |
Disclosed is a propylene direct oxidation reaction catalyst enabling propylene oxide to be prepared from propylene and oxygen in a yield higher than that of a catalyst prepared by a conventional method, by applying a specific transition ...
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WO/2018/038404A1 |
The present invention relates to a method for manufacturing an epoxy reactive diluent which minimizes the amount of epichlorohydrin that is removed in an addition reaction of a branched monocarboxylic acid and epichlorohydrin and a proce...
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WO/2018/031518A1 |
A method for the oxidation of ethylene to form ethylene oxide which comprises: providing an aqueous stream containing ethylene glycol and impurities; introducing the aqueous stream in a first ion exchange treatment bed to reduce the cont...
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WO/2018/027021A1 |
The present invention provides new methods for preparing compound (5), and pharmaceutically acceptable salts thereof, of structure. Compound (5), or a pharmaceutically acceptable salt thereof, is an important intermediate in the synthesi...
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WO/2018/018070A1 |
The present disclosure relates to epoxide containing compounds comprising three benzene units linked by bridging groups. The disclosure also relates to the production of curable epoxy resin formulations comprising said epoxide containing...
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WO/2018/021271A1 |
This method is for producing propylene oxide and comprises (1) an oxidation step, (2) a distillation step, (3) an epoxidation step, and (4) a separation step, wherein: the distillation step (2) is for distilling a reaction mixture contai...
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WO/2018/017453A1 |
A method for producing ethylene oxide comprising: a) providing one or more feed components, wherein the one or more feed components contains at least ethylene obtained by dehydrating ethanol; b) contacting the one or more feed components...
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WO/2018/016376A1 |
The present disclosure provides a reaction of a chlorine-containing compound with use of a flow reactor that has few limits on a solvent to be used therein. According to the present disclosure, a chlorine-containing compound and a reacti...
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WO/2018/016615A1 |
Provided is a compound represented by formula (0). (0) (RY is a C1–30 alkyl group or a C6–30 aryl group; RZ is a C1–60 N-valent group or a single bond; and RT is a C1–30 alkyl group, a C6–30 aryl group, a C2–30 alkenyl group,...
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WO/2018/015430A1 |
The present invention is related to a process for preparing propylene oxide, comprising (i) providing a stream comprising propene, hydrogen peroxide or a source of hydrogen peroxide, water, and an organic solvent; (ii) passing the liquid...
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WO/2018/015435A1 |
The present invention is related to a process for purifying propylene oxide, comprising (i) providing a stream S0 comprising propylene oxide, acetonitrile, water, and an organic compound comprising a carbonyl group -C(=O)-, wherein said ...
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WO/2018/012962A1 |
The invention relates to the production of epoxidized methyl oleate from palm methyl oleate using in-situ epoxidation for preparation of plasticizers. Epoxidized palm-based methyl oleate (referred to as "EPMO") can be prepared by epoxidi...
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WO/2018/005781A1 |
Disclosed herein are methods for preparing [(2S,3R)-N-[(2S)-3-(cyclopent- 1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-
hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)ace
tamido]propanamido]propanamide (compound ...
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WO/2018/005772A1 |
Provided herein is a peptide epoxyketone immunoproteasome inhibitorhaving a structure: Formula (I) wherein X- is a counterion, crystal forms, salts, and processes for making the same, and formulations thereof.
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WO/2018/003677A1 |
Provided is a method for more efficiently producing propylene oxide, and specifically a method for producing propylene oxide comprising 1) an oxidation step, 2) an epoxidation step, 3) a separation step, 4) a cumene conversion step, and ...
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WO/2017/215679A2 |
Disclosed are a pharmaceutical composition of chlorambucil and medical uses thereof to counter depression. The present pharmaceutical composition of chlorambucil contains chlorambucil and a natural-product compound (1) extracted from the...
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WO/2017/215929A1 |
This invention relates to a process for the epoxidation of a tetrasubstituted alkene such as terpinolene to the corresponding epoxide such as terpinolene epoxide by reacting the tetrasubstituted alkene with peracetic acid prepared in sit...
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WO/2017/215928A1 |
This invention relates to a process for the epoxidation of a tetrasubstituted alkene such as terpinolene to the corresponding epoxide such as terpinolene epoxideby reacting the tetrasubstituted alkene with performic acid prepared in situ...
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WO/2017/200339A1 |
The present invention relates to an epoxy compound derived from petroleum by-products, and a preparation method therefor. In addition, the present invention relates to an epoxy composition using the epoxy compound derived from petroleum ...
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WO/2017/198202A1 |
Disclosed are a novel polycrystalline form of 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-me
thyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2
-indolinone (nintedanib), a manufacturing method thereof, and a pharm...
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WO/2017/187156A1 |
The present invention relates to a combination comprising a proteasome inhibitor and a cyclic peptide that comprisesan exposed Arg-Gly-Asp (RGD)moiety;wherein the combination is formulated for oral administration of both the proteasome i...
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WO/2017/184072A1 |
The present invention relates to a grafting agent derived from lignin having the general formula of wherein R1 is selected from substituted or unsubstituted epoxide group, aldehyde group, alkene group, thiol, hydroxyl or a carboxylic aci...
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WO/2017/171329A1 |
The present invention relates to a glycidyl ester compound preparation method for performing a reaction under reduced pressure without using a reaction solvent.
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WO/2017/170915A1 |
According to the present invention, a means for preventing the occurrence of corrosion on the inner tube side of a heat exchanger in an ethylene oxide production process to enable the continuous production of ethylene oxide for a long pe...
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WO/2017/173105A1 |
Reagents for stabilizing the nucleic acids of a biological cell, compositions, kits and methods of use thereof are described. The stabilization reagents may prepare the nucleic acids within the biological cell for storage and preserve th...
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WO/2017/157253A1 |
A process for the preparation of epoxide through a halohydrin process comprises: (1) halohydration: H2O2 (or hydrogen peroxide), halogen elementary substance, ethylenically unsaturated compound having one or more C=C double bonds are add...
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WO/2017/159637A1 |
Disclosed are a monoepoxy compound of formula (1), a curable composition containing the same, a cured product thereof, a method for producing the monoepoxy compound, and a reactive diluent containing the monoepoxy compound. The monoepoxy...
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WO/2017/157254A1 |
Provided is a method for preparing an epoxide by halohydration, the method comprising: (1) halohydration: adding H2O, a halogen element and an olefin compound to a reaction unit for reaction to obtain a halohydrin; (2) saponification: sa...
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WO/2017/156164A1 |
The present invention concerns compounds and their use to treat cardiovascular disease, renal disease, thrombic disease, stroke, metabolic syndrome, cell proliferation, and ischemic cardiovascular disorders. Compounds of the present inve...
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WO/2017/148417A1 |
Disclosed in the present invention are a 2,3-epoxy succinyl derivative, a preparation method therefor, and uses thereof. Specifically, disclosed in the present invention are a compound represented by formula (1), a raceme thereof, an opt...
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WO/2017/141806A1 |
The present invention addresses the problem of providing: a novel ionic compound which can be preferably added to a non-aqueous electrolytic solution for an electrical storage device; a novel non-aqueous electrolytic solution containing ...
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WO/2017/134504A1 |
Methods to produce propylene oxide are described. One method can include providing a propene feed stream, an oxygen feed stream and, optionally, a hydrogen feed stream to a reaction zone, and maintaining, in a reaction zone during the re...
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WO/2017/123576A1 |
Epoxidized fatty acid alkyl esters useful as plasticizers are obtained by reacting epoxidized fatty acid triglycerides with alcohol in the presence of an enzyme having transesterification activity.
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WO/2017/118887A1 |
Methods of co-producing hydrogen and alkylene oxides are described. One method includes obtaining a reaction mixture that includes water, solvent, alkene reactants, water splitting photocatalyst and an epoxidation catalyst; and exposing ...
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WO/2017/102087A1 |
The present invention relates to a method for producing a polyol from an unsaturated fatty acid with one or more double bonds, or a polyol from a fatty acid derivative having at least one unsaturated fatty acid group with one or more dou...
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WO/2017/098532A1 |
The present disclosure provides crystalline carfilzomib form M1 and a process for the preparation thereof. Further disclosed are processes for the preparation of amorphous carfilzomib using crystalline form M1 as a starting material.The ...
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WO/2017/100553A1 |
The present disclosure relates to salts and polymorphs of aminoalkylfumagillol carbamates (e.g., fumagill-6-yl N-(trans-4-aminocyclohexyl)carbamate benzenesulfonic acid salt and fumagill-6-yl N-(trans-4-aminocyclohexyl)carbamate hydroxyn...
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WO/2017/098879A1 |
Provided are: an epoxy resin which has high flowability and, despite this, gives cured objects excellent in terms of heat resistance and moist-heat resistance; a process for producing the epoxy resin; a cured object obtained from the epo...
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WO/2017/093209A1 |
The present invention relates to a process for preparing 3-amino tetrahydropyrans and, more particularly, to an improved method for synthesizing a 2,3,5-substituted tetrahydropyran derivative, intermediate being used in the preparation o...
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WO/2017/091588A1 |
An improved analytical method for analysis of dianhydrogalactitol preparations provides a method for determining the purity of dianhydrogalactitol and detecting impurities in preparations of dianhydrogalactitol, as well as identifying an...
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WO/2017/089076A1 |
Propene is continuously reacted with hydrogen peroxide in a tube bundle reactor comprising a multitude of parallel reaction tubes in the presence of a titanium silicalite catalyst arranged as a fixed bed in the reaction tubes. A cooling ...
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WO/2017/077846A1 |
[Problem] To provide an epoxy resin composition including a reactive diluent for an epoxy resin having low volatility, which does not reduce physical properties of a cured product such as heat resistance and curability to the extent poss...
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WO/2017/077845A1 |
[Problem] To provide a multifunctional epoxy compound which has a low permittivity, and, when added to a generic epoxy resin composition, can achieve a sufficient reduction in permittivity of a cured epoxy resin product obtained from the...
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WO/2017/070878A1 |
The present invention belongs to the field of natural pharmaceuticals and pharmaceutical chemistry, and relates to novel esterified amino acid derivatives of triptolide of general formulae I and II or a pharmaceutically acceptable adduct...
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WO/2017/067634A1 |
The invention relates to the use of hydrophilic compounds of formula (I) as photopolymerization initiators of polymerizable substance mixtures, which contain unsaturated compounds, or to the photochemical cross-linking of linear polymers...
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WO/2017/059102A1 |
Provided herein, inter alia, are compositions and methods useful for treating hvperproliferative diseases, including cancer and non-malignant hvperproliferative diseases.
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WO/2017/037692A1 |
The present invention provides a process for production of fucoxanthin and/or polysaccharides from microalgae and the use of purified fucoxanthin thereof in pharmaceutical, cosmetic, nutraceutical and food compositions.
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