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Matches 451 - 500 out of 6,849

Document Document Title
WO/2014/100438A1
The present invention provides compounds of formula (I) or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein W, X, n, s, t, and Ra are as described herein. The present invention relates generally to selective inhib...  
WO/2014/098015A1
Provided are a 1-aryl-1-heterodiene compound represented by formula (I) or a salt thereof, and a pesticide containing said compound or salt thereof as an active ingredient. In formula (I), Q represents an aryl ring or the like; D2 repres...  
WO/2014/089903A1
Disclosed are a liquid crystal compound containing a cyclobutyl and a difluoromethylenedioxy bonding group as well as a preparation method and an application thereof. The compound is shown in a formula (I). In the molecular structure of ...  
WO/2014/090363A1
The invention relates to the use of 4-oxo-4H-pyran- or 4-oxo-l,4-dihydropyridine derivatives as protein-adhesive active substances, in particular as skin or hair-adhesive and/or skin or hair-binding UV-absorbers, and to the protection of...  
WO/2014/090364A1
The invention relates to protein-adhesive colouring agents, to the production thereof and to preparations containing said colouring agents and to a method for colouring keratin-containing fibres, in particular for colouring human hair.  
WO/2014/088432A1
The invention relates to sphingoglycolipid analogues and peptide derivatives thereof, which are useful in treating or preventing diseases or such as those relating to infection, atopic disorders, autoimmune diseases or cancer.  
WO/2014/086285A1
Disclosed herein is a novel antifungal compound, derivatives that are used b treat fungal infections. In a specific embodiment, the compound is a small molecule. In a specific embodiment, the compound described herein inhibits yeast to h...  
WO/2014/084407A1
The present invention provides a compound having an excellent efficacy for controlling weeds. A dihydropyrone compound of formula (I): wherein m is 1, 2 or 3; n is an integer of any one of 1 to 5; X represents O, S, S(O) or S(O)2; R1 rep...  
WO/2014/081660A1
Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula (I): the various substit...  
WO/2013/106937A9
Equatorial 2,3-fluorinated glycosides compounds of formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza, the methods for their preparation, and their pharmaceutical compositions. The therap...  
WO/2014/074365A1
The present invention provides compounds of Formula I. Wherein Rl, L, and A are as described herein, or a pharmaceutical salt thereof, processes for preparing the compounds, and methods of treating a condition, such as hypertriglyceridem...  
WO/2014/072944A1
The present invention relates to a method for manufacturing organic electronic devices including a dipyrannylidene film as an anodic interface layer, said method being carried out in a vacuum and without any exposure to air. The inventio...  
WO/2014/068443A1
The present invention is directed to novel cytotoxic spliceostatin analogs (I) and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.  
WO/2014/060345A1
The present invention relates to a method for the integrated production of 2-substituted 4-hydroxy-4-methyl tetrahydroprane and of 2-substituted 4-methyl tetrahydroprans in which 3-methylbut-3-ene-1-ol is reacted with an aldehyde in the ...  
WO/2014/058037A1
The present invention provides a compound having an excellent efficacy for controlling weeds. A pyrone compound of formula (I): wherein m is 1, 2 or 3; n is an integer of any one of 1 to 5; X represents O, S, S(O) or S(O)2; R1 represents...  
WO/2014/057078A1
The present application relates to compounds of formula (I), wherein R1 to R5 are as defined in claim 1, a pharmaceutical composition thereof and said compounds for use in the treatment of diseases related with the activity of P2X7 recep...  
WO/2014/058078A1
Disclosed is a process for preparing dihydro-2H-pyran derivatives of formula I: wherein R1 and R2 are defined herein. The process of the invention provides the compound of formula I in concise cascade reactions and in one pot. The compou...  
WO/2014/040457A1
An intermediate of formula (V) used for preparing limaprost of formula (I), preparation method thereof, and preparation method of limaprost therefrom. The present preparation method of limaprost from the intermediate of formula (V) inclu...  
WO/2014/041362A1
The present invention relates to a compound which when exposed to ultraviolet-A (UVA) radiation is cleaved to produce a first compound which is a transition metal chelating compound and a second compound which has antioxidant and/or UV a...  
WO/2014/037560A1
The invention provides a process to separate levulinic acid from a composition obtained by acid hydrolysis of biomass said process comprising subjecting said composition to solvent-solvent extraction to yield an organic phase comprising ...  
WO/2014/038663A1
Provided are: a method for producing a sulfonyl amidine compound, which has an excellent gonadotropin releasing hormone receptor antagonism and is useful as a therapeutic agent for gonadotropin-dependent diseases (for example, prostate c...  
WO/2014/033170A1
Inhibitors of HBV replication of Formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein B, R1, R2 and R4 have the meaning as defined herein. The present invention also relates to pharmaceuti...  
WO/2014/033176A1
Inhibitors of HBV replication of Formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein B, R1, R2 and R4 have the meaning as defined herein. The present invention also relates to processes f...  
WO/2014/028669A1
The present invention relates to aryl sulfones and related compounds that are modulators of ROR-gamma receptors. The invention also provides pharmaceutical compositions comprising these modulators, and methods of modulating ROR-gamma rec...  
WO/2014/025679A1
The present invention is directed to a process for the preparation of heterocyclic derivatives of formula I (I), wherein J, X, Z, W and R2 are as defined herein using a palladium catalysed aminocarbonylation reaction. Such compounds are ...  
WO/2014/016381A1
The invention relates to a crystalline complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D- glucopyranos-1 -yl)-benzene and a natural amino acid, to methods for the preparation thereof, as well as to uses thereof for preparing medicaments.  
WO/2014/015054A1
Disclosed herein are novel pharmaceutical agents which are useful as integrin receptor antagonists that mediate the pathologic processes of angiogenesis and fibrosis and as such are useful in pharmaceutical compositions and in methods fo...  
WO/2014/006250A1
The invention relates to the use of a compound having formula I, in which R1 is an alkenyl group C5-C25 containing one ore more double carbon-carbon bonds, R2 is selected independently from the group consisting of methyl and fluorinated ...  
WO/2013/169651A9
A method of making an anti-Markovnikov addition product is carried out by reacting an acid with an alkene or alkyne in a dual catalyst reaction system to the exclusion of oxygen to produce said anti-Markovnikov addition product; the dual...  
WO/2014/002105A1
The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use ...  
WO/2013/192352A1
The invention provides compounds of formula la, lb and Ic: [Formula Ia, Ib, and Ic] and salts thereof, wherein variables are as described in the specification, as well as compositions comprising a compound of formula Ia-Ic, methods of ma...  
WO/2013/181741A1
The present invention relates to compounds having the general Formula I: which absorb UV radiations and protect biological materials as well as non-biological materials from damaging exposure to UV radiations. The present invention also ...  
WO/2013/180140A1
The present invention provides a novel dihydroorotic acid dehydrogenase inhibitor that is applicable to various diseases. As an active ingredient, a compound represented by formula (I) (wherein X represents a halogen atom; R1 represents ...  
WO/2013/177243A1
A process for making the compound of Formula I utilizes the starting compound, together with sulfilimine and sulfoxide process steps later on.  
WO/2013/160418A1
The present invention is directed to novel retinoid-related orphan receptor gamma (RORγ) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammator...  
WO/2013/161851A1
The present invention pertains to a benzamide derivative represented by formula (I), or a pharmaceutically acceptable salt thereof.  
WO/2013/159224A1
Certain 2-carbamo(thio)yl-1,3-dioxopropyl derivatives, or the tautomers and pharmacologically acceptable addition salts thereof are found to be toxic to cancer cells, in part, by inhibiting DNA topoisomerase II enzyme making them candida...  
WO/2013/158302A1
The invention provides derivatives of DEA which have increased potency and hydrolysis resistance as compared to DEA, and compositions thereof, as well as methods of using these derivatives to promote neurogenesis, neurite growth and/or l...  
WO/2013/152476A1
Provided are methods of making compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides synthetic intermediates useful for preparing such compounds.  
WO/2013/152848A1
The present invention relates to fucose- and mannose-derived glycomimetics and their general use in prophylaxis or treatment of Pseudomonas aeruginosa infections including respiratory tract infections, urinary tract infections, nosocomia...  
WO/2013/147096A1
The present invention provides: a compound represented by formula (I) or a salt thereof; a method for quantitatively analyzing a target substance containing an amino group, which comprises labeling the target substance in at least two sa...  
WO/2013/144394A1
Alternariol and alternariol monomethyl ether are two of the toxins produced in greatest amounts by fungi of the family Alternaria. They occur frequently in foodstuffs and continued consumption thereof may have negative effects on human h...  
WO/2013/146539A1
According to the present invention, PPARs agonist activity is enhanced in order to improve metabolic syndrome, hyperlipidemia, and diabetes. Provided is a compound having a lactone structure comprising formula (9).  
WO/2013/142812A1
The invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, and G are as described in the specification, as well as compositions comprising a compound of formula I, methods of...  
WO/2013/134415A1
The present invention relates to compounds useful for the treatment or prevention of bacteria infections. These compounds have formula I: The invention also provides pharmaceutically acceptable compositions containing the compounds and m...  
WO/2013/130792A2
Fluorinated prodrug compounds as can be used for selective streptococcal mevalonate pathway inhibition.  
WO/2013/125356A1
Provided are: a liquid crystal compound which has high stability with respect to heat, light and the like, high clearing point, low lower limit temperature of the liquid crystal phase, low viscosity, adequate optical anisotropy, large di...  
WO/2013/125777A1
The present invention relates to a biosynthetic gene cluster for a chejuenolide of the marine microorganism Hahella chejuensis, and to the function of an enzyme involving the biosynthetic pathway of a chejuenolide coded by the genes. Sin...  
WO/2013/122028A1
The purpose of the present invention is to provide an aromatic ring compound exhibiting GPR40 agonist activity. The compound represented by formula (I) (refer to the description for information pertaining to each symbol in the formula) o...  
WO/2013/118907A1
An amide compound represented by formula (I) has an excellent pest control effect. (In the formula, Y represents a 3-7 membered saturated heterocyclic ring which contains, as ring-forming component(s), one or more atoms or groups that ar...  

Matches 451 - 500 out of 6,849