Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 751 - 800 out of 6,875

Document Document Title
WO/2009/057938A2
Provided is a method of preparing a (6R)-3-hexyl-4-hydroxy-6-undecyl-5,6-dihydropyran-2-one, and a (5R)-2-hexyl-5-hydroxy-3-iminohexadecanoate derivative used in said method as an intermediate.  
WO/2009/055516A1
The present invention is directed to a process, having a reduced environmental impact, for preparing phenylamino substituted quaternary salt compounds that are CCR2 antagonists.  
WO/2009/055519A1
The present invention is directed to a process, having a reduced environmental impact, for preparing phenylamino substituted quaternary salt compounds that are CCR2 antagonists.  
WO/2009/052191A1
Internally masked neopentyl sulfonyl ester prodrugs of acamprosate, pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating diseases are disclosed. In particular, aca...  
WO/2009/049378A1
The present invention relates to bioactive lactone derivatives of formula (I) and pharmaceutical and pesticidal compositions containing them. The present invention also relates to methods of treating bacterial, protozoan, parasitic and f...  
WO/2009/047568A2
Certain compounds of Formula (I) or salts thereof are suitable for use in the in vitro preservation of living animal cells. The living animal cells may be isolated cells, such as stem cells, or groups of cells such as tissue or an organ.  
WO/2009/038715A1
Disclosed is a process for the preparation of a tetrahydropyran-di-amine represented by Structural Formula (I): wherein R1 is H or alkyl and E is H or an amine protecting group.  
WO/2009/038719A1
Disclosed is a process for the preparation of a tetrahydropyran-di-amine represented by Structural Formula (I): wherein R1 is H or alkyl and E is H or an amine protecting group.  
WO/2009/030716A1
The present invention relates to 1-(1-methylethyl)-4-{[4-(tetrahydro-2H-pyran-4-yloxy)phenyl] carbonyl}piperazine (Formula) or a pharmaceutically acceptable salt thereof, in particular the hydrochloride salt thereof and crystalline forms...  
WO/2009/031437A1
Disclosed is a liquid crystalline compound which has stability to heat, light and the like, exhibits a nematic phase in a wide temperature range, has a low viscosity, adequate optical anisotropy and an adequate elastic coefficient K33, a...  
WO/2009/028284A1
[PROBLEMS] To provide a process for producing an (R)-2-alkylcyclopentanone and an (R)-δ-lactone (which are useful as perfume components or the like) in a simple and inexpensive manner, in high yield and at high optical purity without pu...  
WO/2009/024550A1
The present invention relates to N-benzyl,N' -arylcarbonylpiperazine derivatives having the general Formula (I) to pharmaceutical compositions comprising the same, and to the use of a these N-benzyl,N' -arylcarbonylpiperazine derivatives...  
WO/2009/021943A2
The present invention relates to a process for preparing compounds of the general formula (I) in which R1 and R2 are defined as mentioned in the description, the pharmaceutically acceptable salts thereof and the solvates thereof, which c...  
WO/2009/019900A1
It is intended to provide an industrial purification method for PDC obtained by fermentative production. A purification method for 2-pyrone-4,6-dicarboxylic acid, characterized by allowing a monovalent to tetravalent cationic salt to exi...  
WO/2009/016375A2
Polyglycerol ethers of sorbitan carboxylic acid, particularly C8 to C22 carboxylic acid, esters are new surfactant compounds, useful as emulsifiers. Desirable compounds are of the formula (I): Sor(R1)(R2)(R3)(R4) where R1, R2, R3, R4 hav...  
WO/2009/013764A2
Disclosed herein is an improved process for producing HMG-CoA reductase inhibitor, 6(R)-[2-(8 '(S)-2 ",2 ''-dimethylbutyryloxy-2'(S),6 '(R)-dimethyl- 1', 2', 6', 7', 8',8a'(R)-hexahydronaphthyl-r(S))ethyl]-4(R)-hydroxy-3,4,5,6 -tetrahydr...  
WO/2009/007015A1
The present invention relates to compounds of the formula (I). The compounds of the formula (I) are valuable pharmacologically active compounds. They exhibit a strong anti-thrombotic effect and are suitable, for example, for the therapy ...  
WO/2008/156816A2
The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to ...  
WO/2008/156142A1
It is intended to provide a novel compound which has AT2 receptor agonism and is capable of being expected as a pharmaceutical and to provide a therapeutic or preventive method for various diseases. A novel malonic acid sulfonamide deriv...  
WO/2008/155890A1
It is intended to provide a method for producing aglycone from a glycoside efficiently at low cost without using an acid catalyst or an organic solvent. The method for producing glycoside aglycone, characterized by bringing a glycoside i...  
WO/2008/156817A2
Described are compounds that bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compound...  
WO/2008/156828A2
Described are compounds that bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compound...  
WO/2008/142155A2
The present invention concerns a method for preparing C-6 phosphorylated D- aldohexoses and C-6 phosphorylated D-aldohexose derivatives, new C-6 phosphorylated D-aldohexoses derivatives and uses thereof. The method comprises incubating p...  
WO/2008/141234A2
The invention provides novel compounds that may be used as intermediates in the preparation of epothilones, epothilone analogs and derivative, as well as new synthetic methods for producing the intermediates and products.  
WO/2008/140842A1
Compositions and methods for enhancing heavy metal detoxification are described. The compositions and methods described provide enhanced activity of key detoxification systems including that the induction of phase II detoxification enzym...  
WO/2008/130508A1
Compounds of Formula I are useful inhibitors of HIF prolyl hydroxylases. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.  
WO/2008/126943A2
A method for manufacturing neuraminic acid derivatives is provided, also synthetic intermediates of the neuraminic acid derivatives and methods for their manufacture, and neuraminic acid derivatives having high purity. [Means for solutio...  
WO/2008/125627A1
A compound of formula (I) wherein the substituents have various meanings, optionally in salt and/or solvate form, and their use as pharmaceuticals.  
WO/2008/122329A1
The present invention provides diol compounds, cosmetic or dermatological sunscreen compositions containing these compounds and the use of these compounds as UV-filters. The compounds are particularly advantageous, because they adhere to...  
WO/2008/119810A2
The process for the synthesis of statins featuring the use of an early intermediate (4R,6S)-6-(dialkoxymethyl)tetrahydro-2H-pyran-2,4-diol which already possesses the desired stereochemistry corresponding to the final statin.  
WO/2008/120712A1
Disclosed is a safe prophylactic or therapeutic composition for obesity or a complication thereof, which has an activity of regulating the autonomic nerve activity, particularly an activity of enhancing the sympathetic nerve activity, an...  
WO/2008/116301A1
The present invention relates to novel derivatives of deferiprone. In particular, the present invention relates to fluorinated derivatives of deferiprone or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprisin...  
WO/2008/116029A1
The present invention provides compounds and methods for modulation of the quorum sensing of bacteria. In an embodiment, the compounds of the present invention are able to act as replacements for naturally occurring bacterial quorum sens...  
WO/2008/110307A1
Cyclohexanedione compounds of Formula (I) wherein R1 is methyl, ethyl, n-propyl, iso-propyl, cyclopropyl, halomethyl, haloethyl, halogen, vinyl, ethynyl, methoxy, ethoxy, halomethoxy or haloethoxy, R2 and R3 are, independently hydrogen, ...  
WO/2008/109591A1
Compounds and pharmaceutical compositions comprising them are disclosed that may be useful for the treatment of diseases and disorders such as diabetes and obesity.  
WO/2008/108323A1
Disclosed is a drug for treatment or prevention of H5N1 influenza. Specifically disclosed is a drug for treatment or prevention of H5N1 influenza, which contains a compound represented by the general formula (I) below as an active ingred...  
WO/2008/106047A2
Carbamate compounds having a structure represented by formula (I) (where R1,R2, R3, R4, R5 and R6 are as defined herein) are useful as anti-tumor agents.  
WO/2008/106225A1
The present invention provides cycloalkyl containing macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO/2008/106204A1
The present invention provides amide containing macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO/2008/101914A2
Novel substituted benzamide based inhibitors, their use in therapy, pharmaceutical compositions comprising the compounds, the use of said compounds in the manufacture of medicaments, and therapeutic methods comprising the administration ...  
WO/2008/101885A1
Novel substituted benzamide based inhibitors, their use in therapy, pharmaceutical compositions comprising the compounds, the use of said compounds in the manufacture of medicaments, and therapeutic methods comprising the administration ...  
WO/2008/101886A1
Novel substituted benzamide based inhibitors, their use in therapy, pharmaceutical compositions comprising the compounds, the use of said compounds in the manufacture of medicaments, and therapeutic methods comprising the administration ...  
WO/2008/101938A1
Glucopyranosyl-substituted benzyl-benzonitrilederivatives as defined according to claim 1, including the tautomers, the stereoisomers thereof, the mixtures thereof and the salts thereof. The compounds according to the invention are suita...  
WO/2008/101939A1
Tetrasubstituted glucopyranosylated benzene derivatives of general formula (I) as defined according to claim 1, including the tautomers, the stereoisomers thereof, the mixtures thereof and the salts thereof. The compounds according to th...  
WO/2008/090151A1
The invention provides a new class of compounds exhibiting an inhibitory effect on neuraminidase (NA), hemagglutinin (HA) and structural M2 protein bearing viruses. These compounds are also useful as inhibitors of the replication factors...  
WO/2008/075353A1
The present invention relates to sulfonamide derivatives of formula (I) (wherein R1, R2, R3, R3', R4and R5are as defined in the claims), to pharmaceutical compositions comprising the same, and to uses thereof. Compounds of the invention ...  
WO/2008/071948A2
A compound of formula (1 ) Including pharmaceutically acceptable salts thereof, wherein: R1 is aryl or heteroaryl optionally substituted with R8; R2 is H or alkyl or CH2 (when forming part of a ring with R3, R4 or R5); R3 is H, alkyl, CH...  
WO/2008/071405A1
Pyrandione, thiopyrandione and cyclohexanetrione compounds, which are suitable for use as herbicides.  
WO/2008/070496A2
This present invention provides for cholesteryl ester transfer protein (CETP) inhibitors, of formula Ia and Ib / pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels...  
WO/2008/067911A1
The invention relates to new compounds of the formula (I) in which W, X, Y, Z and CKE have the meanings given above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides, an...  

Matches 751 - 800 out of 6,875