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Matches 401 - 450 out of 6,875

Document Document Title
WO/2015/111529A1
Provided are: a near-infrared absorbing composition which provides a cured film that has high transmittance in the visible light region and exhibits high shielding performance in the near-infrared region; a near-infrared blocking filter;...  
WO/2015/108136A1
The present invention provides: a novel α-substituted glycinamide derivative or a pharmacologically acceptable salt thereof; a pharmaceutical composition containing the compound or the pharmacologically acceptable salt; and a use of the...  
WO/2015/103510A1
Described are RORγ modulators of the formula (I), [INSERT CHEMICAL STRUCTURE HERE] or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided...  
WO/2015/103507A1
Described are RORϒ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions ...  
WO/2015/103508A1
Described are RORγ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions ...  
WO/2015/089137A1
The present invention is directed to acylguanidines which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPHl), that are useful in the treatment of diseases or disorders associated with peripheral serotonin inclu...  
WO/2015/078802A1
The present invention relates to compounds of general formula (I), wherein the groups R1, R2, R3, X, m and n are defined as in claim 1, wich have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate ...  
WO/2015/074135A1
The present invention relates to a novel family of protein kinase inhibitors, more specifically the present invention is directed to inhibitors of the members of the Tec or Src protein kinase families. The present invention also relates ...  
WO/2015/052283A1
The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof : It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses as anti-prolife...  
WO/2015/049940A1
The present invention relates to a compound having a 2,6-difluorophenyl ether structure, which is useful as an organic electronic material or a medicinal or agrochemical agent, particularly a material for liquid crystal display elements....  
WO/2015/044849A1
The present invention provides a process for the preparation of (1C)-2,3,4,6-tetra- O-acetyl-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D -glucitol of Formula III. The invention also provides a process for the purification of dapa...  
WO/2015/042397A1
Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associat...  
WO/2015/040571A1
The present invention provides an improved process for the preparation of dapagliflozin.of Formula (II) wherein the process comprises the step of hydrolyzing the compound of Formula (III) in the presence of an amine base.  
WO/2015/032942A1
The invention relates to a compound of Formula (I) and its use as a selective dipeptidyl peptidase I inhibitor, as well as pharmaceutical compositions comprising said compound, and methods of treatment involving said compounds.  
WO/2015/032943A1
The invention relates to compounds of Formula (I) and its use as a selective dipeptidyl peptidase I inhibitor, as well as pharmaceutical compositions comprising said compounds, and methods of treatment involving said compounds.  
WO/2015/032945A1
The invention relates to compounds of Formula (I) and their use as selective dipeptidyl peptidase I inhibitors, as well as pharmaceutical compositions comprising said compounds, and methods of treatment involving said compounds.  
WO/2015/032357A1
Zanamivir, a Zanamivir intermediate compound (formula 2), and a preparation method therefor. The preparation method is method 1 or 2. Method 1 comprises the following steps: compound 3 undergoes a reaction to remove a protecting group so...  
WO/2015/031295A1
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, vi...  
WO/2015/030189A1
Provided is a compound which exhibits bone formation acceleration activity (and/or bone resorption suppression activity). The compound is either a compound having a general formula (I) (wherein the substituents are as defined in the desc...  
WO/2015/025859A1
A radiation-sensitive resin composition that comprises a polymer having an acid-dissociable group-containing structural unit, a compound comprising a radiolytic onium cation and a counter anion, and a solvent, wherein the counter anion h...  
WO/2015/008779A1
The present invention relates to a compound represented by formula (I) (In the formula, Ar is a substituted or unsubstituted aromatic group, R is a substituted or unsubstituted hydrocarbon group, or a substituted or unsubstituted heteroc...  
WO/2015/002230A1
The present invention relates to compounds (I), which have RORγt inhibitory effects, and salts thereof. In formula (I), each notation is as described in the Specification. (I)  
WO/2014/206349A1
The present invention relates to an oxa-thia-bicyclo[3.2.1]octane derivative, a preparation method, and use of same, and particularly to an oxa-thia-bicyclo[3.2.1]octane derivative represented by the general formula (I) or a hydrate, a s...  
WO/2014/202168A1
Compounds of the formula I in which R1, R4, R6, R, X1, X2, X3, X4, q and W have the meanings indicated in Claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, card...  
WO/2014/197169A1
A method for protecting a phenol group on a precursor compound is provided. The method includes reacting the phenol group with dihydropyran in an acid catalyzed protection reaction and quenching the protection reaction with a strong base...  
WO/2014/195553A1
The invention relates to a compound of formula (I), where R is selected from a methyl group or an ethyl group (I), the hydroxy acid forms of said compound, the pharmaceutically acceptable salts of said hydroxy acids, and pharmaceutically...  
WO/2014/191535A1
The present invention relates to a compound of formula (I): wherein: X is methyl or chlorine; R1 is fluorine or bromine; R2 is ethynyl, C1-C3alkoxy, C1-C3haloalkoxy, or C1-C3alkoxy-C1-C3alkoxy-; and Q is a pyran-3,5-dione-4-yl, a thiopyr...  
WO/2014/191578A1
Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from (II) and...  
WO/2014/192023A1
The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use ...  
WO/2014/191534A1
The present invention relates to a compound of formula (I): wherein: X is methyl or chlorine; R1 is fluorine or bromine; R2 is ethynyl, C1-C3alkoxy, C1-C3haloalkoxy, or C1-C3alkoxy-C1-C3alkoxy-; and Q is a pyran-3,5-dione-4-yl, a thiopyr...  
WO/2014/189926A1
A method to prepare coumalic acid comprising (a) heating a solution in dichloroethane of malic acid and sulfuric acid or a solution in dichloroethane of malic acid and a perfluorosulfonic acid or (b) adding an acid comprising sulfuric ac...  
WO/2014/189347A1
The present invention provides a novel compound isolated from a plant of the genus Quamoclit and a method for preparing a novel compound isolated from a plant of the genus Quamoclit through chemical synthesis, and relates to a novel comp...  
WO/2014/184311A1
The present invention relates to a method for producing dehydro rose oxide by reacting isoprenol and prenal in the presence of at least one sulfonic acid of formula R1-SO3H as catalyst, wherein R1 is selected from phenyl which carries 2 ...  
WO/2014/177486A1
The invention relates to a method for producing 2-substituted 4-hydroxy-4-methyl-tetrahydropyrans.  
WO/2014/177593A1
The present invention relates to Amorfrutin analogues and stereoisomeric forms, solvates, hydrates, conjugates and/or pharmaceutically acceptable salts of these compounds as well as pharmaceutical compositions containing at least one of ...  
WO/2014/178381A1
Provided is a new compound having glycogen synthase activation potency, but minimal activation of receptor PPAR, and a high degree of safety. A compound represented by general formula [I], or a pharmaceutically acceptable salt thereof....  
WO/2014/177484A1
The invention relates to a method for producing 2-substituted 4-hydroxy-4-methyl-tetrahydropyrans.  
WO/2014/174126A1
The invention relates to derivatives of pyrylium of formula I where the substituents have the meaning defined in the description, used as fluorescent nitric oxide sensors.  
WO/2014/168211A1
Disclosed is a method for producing 2-(4-tetrahydropyranyl)imidazole and/or an acid salt thereof, which comprises a step of producing 2-(4-tetrahydropyranyl)imidazole represented by general formula (4) and/or an acid salt thereof from a ...  
WO/2014/156184A1
[Problem] To provide: an organic photoelectric conversion element which has good response speed, carrier transport properties (sensitivity) and heat resistance; and an imaging element which is provided with this organic photoelectric con...  
WO/2014/160649A1
This invention pertains generally to antibacterial organic compounds of Formula I as described herein, and pharmaceutical compositions containing such compounds. In certain aspects, the invention pertains to treating infections caused by...  
WO/2014/146606A1
The present invention relates to a C-triaryl glucoside SGLT-2 inhibitor shown as formula (I), preparation methods therefor, pharmaceutical compositions thereof and uses thereof for treating diseases that benefit from inhibiting SGLT-2. S...  
WO/2014/146491A1
The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.  
WO/2014/139447A1
Provided in the present invention is a crystal form A of (1S)-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1,6-dideoxy-D-glu cose, characterized in that X-ray powder diffraction as shown by angle 2θ has diffraction peaks around 3.56, 5.42, 10....  
WO/2014/141979A1
The present invention is a radiation-sensitive resin composition which contains a radiation-sensitive acid generator and a polymer having a structural unit that contains an acid-cleavable group, and wherein the radiation-sensitive acid g...  
WO/2014/142329A1
An organic charge transfer complex obtained from an electron acceptor molecule and an electron donor molecule, wherein the electron acceptor molecule is PDC or a PDC derivative.  
WO/2014/138053A1
In one aspect, the invention relates to compounds having the formula: (I) where R1-R5 and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In anoth...  
WO/2014/130613A2
Compounds of Formula (I) are useful as modulators of glycosylation. Compounds of Formula (I) have the following structure: (I) and the definitions of the other variables are provided herein.  
WO/2014/129268A1
Provided are: a liquid crystal compound satisfying at least one property such as high stability to light, high clearing point, low minimum temperature of the liquid crystal phase, low viscosity, suitable optical anisotropy, large dielect...  
WO/2014/125231A1
The invention relates to a method for the synthesis of 4-(heterocycloalkyl)-benzene-1,3-diol compounds of general formulae (I) and (III) wherein X can be an oxygen atom or a sulphur atom. The invention also relates to a method for the sy...  

Matches 401 - 450 out of 6,875