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WO/2022/167700A1 |
The present invention relates to chromen-4-one derivatives, and to associated multi-salts, solvates, prodrugs and pharmaceutical compositions. The present invention also relates to the use of such compounds and compositions in the treatm...
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WO/2022/167699A1 |
The present invention relates to chromen-4-one derivatives, and to associated multi-salts, solvates, prodrugs and pharmaceutical compositions. The present invention also relates to the use of such compounds and compositions in the treatm...
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WO/2022/167867A1 |
The present disclosure relates in part to chemical modulators of protein phosphatase 2A (PP2A). The compounds of the present disclosure are useful in treating, preventing, and/or ameliorating cancer, diabetes, autoimmune disease, solid o...
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WO/2022/167698A1 |
The present invention relates to chromen-4-one derivatives, and to associated multi-salts, solvates, prodrugs and pharmaceutical compositions. The present invention also relates to the use of such compounds and compositions in the treatm...
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WO/2022/161895A1 |
The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive chromophore, special polymerized compounds, and special monomer compounds being particularly suitable for compositions an...
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WO/2022/165165A1 |
Non-naturally occurring compositions comprising tetrahydrocannabinol (THC) and limonene and their use for treating THC-induced anxiety and/or paranoia are disclosed.
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WO/2022/162471A1 |
Disclosed are compounds, compositions, and methods useful for treating neuronal and mitochondrial diseases.
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WO/2022/165432A1 |
Disclosed herein are compounds that inhibit cullin-RING E3 ubiquitin ligase 4, a method of inhibiting the catalytic activity of a Cullin-RING E3 Ubiquitin (Ub) Ligase (CRL) in a cell, compositions comprising the inhibitor compounds, a me...
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WO/2022/162121A1 |
The present invention relates to butyrate compounds as well as to their synthesis and their use. Such compounds are very useful compounds, either as such or as intermediates in organic synthesis.
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WO/2022/160455A1 |
The present invention relates to the field of natural medicines, and particularly provides a compound for preventing and treating inflammation. The compound has a structure, as shown in formulas I-VIII, and belongs to a 2-(2-phenethyl) c...
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WO/2022/159504A1 |
This invention relates to deuterated tetrahydrocannabinol compounds, deuterated tetrahydrocannabivarin compounds, deuterated cannabigerol compounds, and deuterated cannabichromene compounds, methods for preparation thereof, compositions ...
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WO/2022/155741A1 |
The present disclosure describes cannabis products and methods for producing one or more activated cannabinoids, comprising decarboxylating one or more cannabinoid acids in a cannabis source; and grinding the cannabis source; to produce ...
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WO/2022/155757A1 |
The present disclosure relates to a cannabinoid emulsification system for making cannabis-infused products, particularly cannabis-infused products that include an aqueous component. The cannabinoid emulsification system comprises a canna...
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WO/2022/157338A1 |
Method for the production of cannabinoid acid esters of general formula (I) or (II) or (III) or (IV), wherein R1 consists of a straight or branched alkyl group, alkenyl group or alkynyl group having from 1 to 5 carbons, during the simult...
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WO/2022/150435A1 |
This invention is directed to pharmaceutical compositions comprising tocotrienol and the use of such compositions to treat non-alcoholic steatohepatitis.
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WO/2022/149610A1 |
[Problem] To provide a guanidine derivative (in particular, an amino acid compound having a 4-guanidino group) which has a low production cost and is less likely to cause the problem of waste liquor, a method for producing the same and a...
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WO/2022/147872A1 |
The present invention relates to a series of amide derivative neutral mitochondrial fluorescent markers, a preparation method therefor, and an application thereof; the present invention discloses for the first time that, after being link...
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WO/2022/150681A1 |
The technology described herein is directed to methods and compositions for inhibtion of ClbP and the treatment and/or prevention of cancer, e.g., colorectal cancer, a urinary tract cancer, a squamous cell carcinoma, an oral squamous cel...
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WO/2022/140849A1 |
The present disclosure relates to cannabinoid compositions that have reduced bitter-tasting characteristics, which are suitable for making cannabis-infused products. The cannabinoid compositions effectively mask the bitter and off-taste ...
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WO/2022/146914A1 |
Described herein are compounds and methods of treating a disease or disorder, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, ischemic stroke, and prion disease, comprising administering a therapeutically effectiv...
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WO/2022/143715A1 |
An oxaspiro substituted pyrrolopyrazole derivative, an intermediate thereof, and a preparation method therefor.
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WO/2022/144436A1 |
The present invention refers to a process for the asymmetric synthesis of isopiperitenol and successor compounds.
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WO/2022/138967A1 |
The present invention provides a photochromic compound which is represented by general formula 1. In general formula 1, each of R30 and R31 independently represents a linear or branched alkyl group having two or more carbon atoms with or...
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WO/2022/138965A1 |
Provided is a photochromic composition comprising one or more types of compounds represented by general formula A and one or more types of compounds represented by general formula B. In general formula A, R1, R2, B1, and B2 each independ...
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WO/2022/135072A1 |
Provided in the present invention are a coumarin compound, a preparation method therefor, and the use and a pharmaceutical composition thereof, belonging to the technical field of medicines. The coumarin compound provided in the present ...
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WO/2022/138735A1 |
Although compounds for treating or ameliorating malignant diseases have been proposed, patients had to endure a large burden since many of such compounds could not be orally ingested. Mangiferin has an effect of ameliorating malignant di...
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WO/2022/138605A1 |
The present invention addresses the problem of providing a method for efficiently producing a peptide having a high purity, a reagent for forming a protective group having excellent deprotection properties, and a novel fused polycyclic c...
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WO/2022/138968A1 |
This photochromic composition contains a predetermined combination of: at least one photochromic compound represented by general formula 1; and at least one selected from the group consisting of a photochromic compound represented by gen...
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WO/2022/138909A1 |
[Problem] The present invention provides: an equol clathrate having improved solubility in water; an equol-absorbent composition containing the equol clathrate; a production method for the clathrate; and an equol-absorbent composition co...
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WO/2022/138966A1 |
Provided is a photochromic composition containing one or more types of compounds represented by general formula A, one or more types of compounds represented by general formula B, and one or more types of compounds represented by general...
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WO/2022/133027A1 |
Compounds of formula (1) wherein R1 represents a -C(R2)(R3)-[C(R4)(R5)]m-L-R6 group or -R7; and the preparation and the therapeutic uses of the compounds of formula (1) as agonists of TRPM8 receptors, useful especially in the treatment o...
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WO/2022/133362A1 |
Disclosed are facile methods of purifying a cannabis extract to produce highly purified, crystallized cannabinoid acids, and in particular cannabinoid acids such as THCA, and removing impurities from the same, by using polar aprotic solv...
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WO/2022/128832A1 |
The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive chromophore, said polymerized compounds, and special monomer compounds being particularly suitable for compositions and o...
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WO/2022/125966A1 |
A method of removing THC and/or THCA from a mixture, the mixture including THC and/or THCA and at least one cannabinoid is provided. The method comprises passing a first feedstock stream through a first chromatographic resin arranged in ...
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WO/2022/124994A1 |
Provided is a method for coupling flavonoid-containing compounds to provide flavonoid dimers, trimers and oligomers. The method comprises contacting a flavonoid-containing compound with base in the presence of air. Flavonoid dimers, trim...
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WO/2022/122975A1 |
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as a drug, especially as an antibiotic. The present invention also relates to a pharmaceutical composition c...
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WO/2022/115953A1 |
The present disclosure describes compositions including a eutectic matrix that includes methylsulfonylmethane and a sugar alcohol and particles of a nutraceutical in the eutectic matrix. In some embodiments, the sugar alcohol:methylsulfo...
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WO/2022/120048A1 |
The present disclosure is directed to chromane compounds, chromane compounds demonstrating HDAC inhibition, and pharmaceutical compositions thereof. Additional embodiments include methods of using the chromane compounds. For example, the...
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WO/2022/118303A1 |
The present disclosure relates to methods of treating cancer and, more particularly, an active agent selected from the group consisting of tetrahydrocannabinol (THC), cannabidiol (CBD), or combinations thereof, in a dosage form for trans...
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WO/2022/118186A1 |
It is provided a senotherapeutic compound comprising a synthetic derivative of flavones, according to the formula (I), in which at least two of R2-R6 are H, and the remainder are individually selected from: H, OH, R1, OR1, NO2, NH2, NHR1...
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WO/2022/115973A1 |
Disclosed are methods for precipitation of CBDA-amine salts and THCA-amine salts from concentrated crude complex extracts. The crude complex extracts may be recovered from cannabis biomass or fermentation systems wherein microorganisms w...
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WO/2022/109736A1 |
Described herein is a polypeptide encoding a prenyltransferase for prenylating a polyphenol and a polypeptide encoding an O-methyltransferase for methylating a polyphenol. For example, the polypeptide comprises or consists of the sequenc...
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WO/2022/113047A1 |
This invention relates to compounds that are 4'-substituted analogues of the flavonol Fisetin. In particular, the invention relates to such compounds wherein the 4' position on the B-ring is substituted with a ring deactivating group whi...
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WO/2022/110381A1 |
An oxygen heterocyclic compound, use thereof and an electronic device using same. The oxygen heterocyclic compound comprises an aromatic amine and an oxygen heterocyclic ring. The aromatic amine can effectively improve hole injection and...
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WO/2022/111586A1 |
Disclosed is a method for purifying cannabinoid compounds that enables cannabinoid compounds to be obtained more economically and with a better purification effect.
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WO/2022/111578A1 |
A stellate compound that has a significant anti-coronavirus spike protein targeting ability and that has a certain broad spectrum. The described class of molecule and salt thereof have at least one R(x)… basic unit, which binds at an o...
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WO/2022/104327A1 |
The present invention is directed to nanoparticles comprising: (a) an inner core comprising oligomeric (-)-epigallocatechin gallate (OEGCG), (b) an outer core comprising a polyethylene glycol-epigallocatechin gallate conjugate (PEG-EGCG)...
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WO/2022/099810A1 |
A tetraphenylethylene compound, an application thereof, and an electronic device using same. The structural general formula of the tetraphenylethylene compound is shown in formula 1. The tetraphenylethylene compound contains an aromatic ...
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WO/2022/102590A1 |
Provided is an anti-viral agent, and in particular, an anti-viral agent for coronaviruses such as SARS-CoV-2. This anti-viral agent contains a tea component.
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WO/2022/099930A1 |
Disclosed is a preparation method for cannflavin compounds. The preparation method has the advantages of cheap and easily available raw materials, few reaction steps, short production period, simple operation, etc. The method comprises: ...
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