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Matches 401 - 450 out of 15,235

Document Document Title
WO/2019/059344A1
The present invention addresses the problem of providing a novel chemically activated water-soluble prodrug. The present invention provides a compound represented by formula (1), or a pharmacologically acceptable salt thereof (in the for...  
WO/2019/057821A1
The invention provides novel coumarin derivatives as specific mitochondrial RNA polymerase inhibitors for the treatment of cancer.  
WO/2019/056123A1
Pharmaceutical compositions comprising one or more cannabinoids and a pharmaceutically acceptable carrier are disclosed. The compositions are in a form suitable for topical administration, and are useful in the treatment of pain. The can...  
WO/2019/056128A1
Compositions comprising two or more cannabinoids, a terpene, and a flavonoid suitable for use in treating insomnia are disclosed. In preferred embodiments, the cannabinoids are cannabidiol and tetrahydrocannabinol, while the terpenes and...  
WO/2019/056129A2  
WO/2019/054386A1
Provided is a heterocyclic compound represented by general formula (I), or a pharmacologically acceptable salt of the heterocyclic compound. In general formula (I): X represents O or NH; R1 represents a substituted or unsubstituted aryl ...  
WO/2019/030762A3
The present invention discloses a cannabinoid-based composition useful for treating or preventing dental pulp associated diseases. The composition comprises an effective amount of cannabis extract or a derivative thereof or at least one ...  
WO/2019/054633A1
The present invention provides a novel heterocyclic compound and an organic light-emitting device using same.  
WO/2019/053605A1
The present invention provides an environmentally benign, facile process for preparation of Tocotrienols from commercially available derivatives of o-Cresol.  
WO/2018/045217A8
Described herein are methods of treating neuron inflammation conditions, for example, Alzheimer's disease, Parkinson's disease, Huntington's disease, ischemic stroke, and prion disease, comprising administering a therapeutically effectiv...  
WO/2019/044672A1
[PROBLEM] To provide a novel method for synthesising a polyphenol. [SOLUTION] A polyphenol production method including the reaction of catechin in the presence of a catalyst and an oxidising agent, said catalyst comprising a metal oxide ...  
WO/2019/043259A1
The invention relates to cannabinoids and their isolation and purification and to obtaining them by means of centrifugal partition chromatography and pH-zone refining.  
WO/2019/043251A1
The present invention relates to novel compounds which are particularly useful for the synthesis of novel chromanol derivatives. These compounds have interesting properties. Particularly, the novel chromanol derivatives have interesting ...  
WO/2019/044872A1
The present invention addresses the problem of providing a rhodamine-based dye which is capable of suppressing fluorescent yield and forming an aggregate even under low concentration conditions. The present invention pertains to a compou...  
WO/2019/044736A1
The present invention provides a detection method and detection probe for colibactin and colibactin-producing bacteria. The present invention provides, for example, the detection of myristoyl-asparagine using a tissue sample or stool sam...  
WO/2019/038361A1
The present invention relates to medicaments for use in the prophylaxis or treatment of vasoconstriction related disorders or conditions. Specifically, the present invention relates to (2R) enantiomeric form of a 6-chromanol derivative f...  
WO/2019/038360A1
The present invention relates to the (S) enantiomeric form of certain 6-chromanol derivatives for use as a medicament. Especially, the present invention relates to the (S) enantiomeric form of a 6-chromanol derivative for use as a medica...  
WO/2019/038739A1
Pharmaceutical and nutraceutical compositions suitable for transdermal administration of plant-derived medicinal compounds are disclosed. The compositions comprise ground plant material (plant flour) and a dermally acceptable adhesive. I...  
WO/2019/033164A1
A method for demethylating a methylated phytocannabinoid compound of Formula I to form a phytocannabinoid compound of Formula II: Formula I Formula II wherein: R1 is selected from the group consisting of: substituted or unsubstituted C1-...  
WO/2019/033168A1
method for decarboxylating a carboxylated phytocannabinoid compound of Formula I to form a phytocannabinoid compound of Formula II: Formula I Formula II wherein: R1 is selected from the group consisting of: substituted or unsubstituted C...  
WO/2019/030631A1
The present invention relates to novel compounds based on 3- ketocoumarins, which are useful as photoinitiators and sensitizer and to compositions thereof. More particularly, the novel compounds comprise a polyhydroxy polymeric core, whi...  
WO/2019/032609A1
Chromatography systems and methods for using carbon dioxide to separate one or more cannabis-derived compounds from other components of a mixture are generally described. Some of the methods described herein comprise transporting a mixtu...  
WO/2019/027040A1
A compound represented by formula (1) (in the formula, R1-R8, R11-R18, R21-R28, R31-R38, X, Y, L1, L2, L3, and Ar are as defined in the specification) provides an organic electroluminescent element having a low drive voltage and exceptio...  
WO/2019/027263A1
The present application provides a heterocyclic compound represented by Chemical Formula 1, and an organic light-emitting element including same.  
WO/2019/023803A1
Powdered cannabis extracts and methods for obtaining powdered cannabis extracts are described. In an aspect, the present application describes a method of preparing a single-serve container which may be configured for receipt in a single...  
WO/2019/022002A1
A compound represented by formula (I) or a salt thereof. (In formula (I), Q1 represents an (un)substituted C6-10 aryl group; Q2 represents an (un)substituted C1-6 alkyl group, an (un)substituted C6-10 aryl group, or a five- to ten-member...  
WO/2019/019792A1
The present invention relates to a coumarin (ketone) oxime ester compound of formula (I), wherein the n and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compound has a very strong ultraviolet absorption in a range...  
WO/2019/020738A1
The present invention describes a process for the production of (-)-cannabidiol (CBD) from industrial hemp by means of an extraction followed by two alternative working processes: a process A which provides extraction with solvents first...  
WO/2019/018455A1
Methods of treating autoimmune microvascular conditions using diosmin or diosmetin are described, particularly the treatment of digital ulcers in systemic sclerosis.  
WO/2019/013542A1
The present specification relates to a heterocyclic compound represented by chemical formula 1 and an organic light emitting element comprising the same.  
WO/2019/012166A1
Compounds with a drimenyloxyarene structure and derivatives, and the use thereof to treat infections caused by phytopathogenic fungi, as fungistatic agents with a low ecological impact. The present invention comprises compounds with the ...  
WO/2019/013249A1
A chromene compound showing a reduced matrix dependency and having at least one indenonaphthopyran structure which carries a group forming a spiro ring together with the carbon atom at the 13-position, wherein the indenonaphthopyran stru...  
WO/2019/013526A1
The present specification provides a compound represented by chemical formula 1 and an organic light emitting device comprising the same.  
WO/2019/012000A1
The present invention relates to a novel synthetic pathway for alpha- tocopherol. The invention discloses different reactions yielding some new intermediates in a very high yield and stereoselectivity.  
WO/2019/009257A1
The problem to be solved by the present invention is to provide a method for producing a flavone having a malonyl group added to glucose located at position-7 therein using a polynucleotide encoding a protein having an activity to transf...  
WO/2019/008537A1
There is provided a medical compound comprising a synthetic flavone derivative, according to the formula (I) with allotment in position C-3 of a group as shown below: Formula (I) wherein at least two of R2-R6 a re H, and the remaining ar...  
WO/2019/007447A1
The present invention provides compounds suitable for use in the treatment of conditions where it is beneficial to halt bone loss and kill cancer cells, particularly in metastases to and primary tumours in the bone and surrounding tissue...  
WO/2019/010419A1
A method for purification and separation of cannabinoids, such as cannabidiol and tetrahydrocannabinol, e.g., from the dried hemp and cannabis leaves can use a continuous simulated moving bed process and a combination of one or more of a...  
WO/2019/004790A1
The present specification relates to a heterocyclic compound represented by Chemical Formula 1, and an organic light emitting element including same.  
WO/2018/148816A4
The invention describes extracts from plants of the genus Stachytarpheta enriched with ipolamiide derivatives as immunosuppressants for treating immunological disorders. The isolated active compounds and a process of producing these are ...  
WO/2019/004612A1
The present invention provides a novel heterocyclic compound and an organic light-emitting device using same.  
WO/2019/004791A1
The present specification relates to a heterocyclic compound represented by Chemical Formula 1, and an organic light emitting element including same.  
WO/2019/004796A1
The present invention provides a novel heterocyclic compound and an organic light-emitting device using same.  
WO/2018/236913A1
Small molecule calpain modulator compositions and pharmaceutical compositions can be prepared and used as therapeutic agents. Exemplary compositions include non-macrocyclic a-keto amide derivatives. The therarapeutic agents can be used f...  
WO/2018/233696A1
Disclosed are a class of coumarin-like cyclic compounds as MEK inhibitors and pharmaceutical compositions comprising the compounds, and the use of same in the preparation of a drug for treating MEK-related diseases. Particularly disclose...  
WO/2018/234643A1
The present invention concerns type II photoinitiators for the free-radical crosslinking of silicone compositions, in particular acrylic silicone compositions. The present invention concerns a silicone composition C1 that can be crosslin...  
WO/2018/232527A1
The present invention describes complex topical aqueous compositions for the effective delivery of active ingredients such as putrescine and Vitamin C into the skin. These compositions may be used in a variety of cosmetic and therapeutic...  
WO/2018/233483A1
Provided are phenylquinolinone and flavonoid derivatives and preparation methods therefor, wherein the derivatives are histamine H3 receptor antagonists, which can protect and restore the normal function of the central nervous system; an...  
WO/2018/235926A1
The purpose of the present invention is to provide an α, β-unsaturated amide compound or a pharmaceutically acceptable salt thereof or the like, which has anti-cancer activity or the like. An α, β-unsaturated amide compound represent...  
WO/2018/230936A1
The present invention relates to a composition for treating metabolic diseases containing a novel compound or a pharmaceutically acceptable salt thereof as an active ingredient. In particular, unlike the PPARγ agonist rosiglitazone, whi...  

Matches 401 - 450 out of 15,235