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WO/2024/051666A1 |
Disclosed are a dibenzylbutyrolactone glycoside compound as shown in formula (I), a stereoisomer, a tautomer or a pharmaceutically acceptable salt thereof, a preparation method therefor, a pharmaceutical composition containing same, and ...
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WO/2022/118321A1 |
The present invention relates to a process for the preparation of Eribulin.
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WO/2021/150806A1 |
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV) or HMPV. The present invention further relates to pharmaceutical...
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WO/2020/249473A1 |
The invention relates to a process for the carbonylation of epoxides in the presence of catalyst systems, wherein the carbonylation takes place in the presence of carbon monoxide, and wherein the catalyst system contains a molybdenum-bas...
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WO/2019/015599A1 |
Provided is a process for producing a compound I comprising at least one functional group chosen in the group consisting of epoxy group, hydroxyl group and carbonyl group and by reacting a compound J comprising at least one functional gr...
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WO/2018/124978A1 |
This present invention relates to a catalyst composition for a production process of δ-lactone from carbon dioxide and 1,3 -butadiene that can efficiently catalyze the synthesis reaction of δ-lactone with good selectivity of δ-lactone...
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WO/2017/155442A1 |
Disclosed is a production equipment for production of a caprolactone by reaction between peracetic acid, produced from acetic acid and hydrogen peroxide, and cyclohexanone, said equipment being split into a first section (Fig. 1) wherein...
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WO/2017/155441A1 |
Disclosed is a production equipment for production of a caprolactone by reaction between peracetic acid, produced from acetic acid and hydrogen peroxide, and cyclohexanone, said equipment being split into a first section (Fig. 1) wherein...
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WO/2017/077549A1 |
The invention discloses a novel analogues of Angiopterlactone B of formula (I) and process for the synthesis thereof. Further the present invention discloses a total synthetic one pot process for the synthesis of Angiopterlactone B and i...
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WO/2016/103677A1 |
Provided is a method for producing a compound represented by Formula (III) while the production of by-products due to, for example, dimerization of a raw material or isomerization of a double bond position is suppressed. The method is a ...
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WO/2016/079692A1 |
The instant invention relates to a composition useful as a nutritional supplement comprising acetylated neuraminate (NeuAc), and/or a compound selected from N-acetyl mannosamine (ManNac), at least one or more compounds of the NeuAc biosy...
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WO/2015/073889A1 |
The present invention provides methods for preparing a C6-C10 alkane, and mixture thereof. The methods include forming a reaction mixture containing an angelica lactone dimer, a catalyst, and a hydrogen source under conditions sufficient...
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WO/2014/159741A1 |
The present disclosure provides methods for purifying a 5-(halomethyl)furfural composition, including 5-(chloromethyl)furfural, at operating conditions that decrease or minimize the decomposition or degradation of 5-(chloromethyl)furfura...
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WO/2014/140017A1 |
This invention relates to a novel method for the preparationof 3-oxotetrahydrofurancomprising oxidating 3-hydroxy-tetrahydrofuran in the presence of a catalytic amount of TEMPO with trichloroisocyanuric acid.
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WO/2012/118943A1 |
The compound according to Formula I is an intermediate in the synthesis of prostacylin analogs. The present invention provides an efficient method for synthesizing a Formula I compound.
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WO/2012/027521A1 |
Molecules having the following structure are disclosed. Processes of using such molecules are disclosed.
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WO/2009/126852A1 |
An enhanced process for the production of a dianhydrosugar, such as isosorbide, from the corresponding sugar alcohol is described. The sugar alcohol is combined with an acid catalyst and reacted at elevated temperatures and at atmospheri...
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WO/2005/113533A9 |
The invention relates to a process for preparing saturated or unsaturated lactones. This process involves reacting a bicyclic compound or a monocyclic compound with hydrogen peroxide in the presence of a first acid having a pKa of 3 or l...
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WO/2009/105969A1 |
The invention discloses novel epothilone analogues, their pharmaceutical compositions, their use and their preparations, especially discloses the compounds of the following formula, their preparations and their use for preparing therapeu...
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WO/2009/042708A1 |
A regenerative anti-inflammatory composition is described to include 1 to 2 percent of comenic acid and 0.55 to 1.1 percent of sodium hydrocarbonate in a water solution, with an optional additive of up to 2.5 percent of benzyl-comenic ac...
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WO/2008/081568A1 |
Disclosed are: a novel dinoflagellate alga; and a macrolide compound which can be used as a novel anti-cancer agent. Specifically disclosed is a macrolide compound produced by a dinoflagellate Amphidinium sp. strain HYA002 or HYA0024. Th...
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WO/2008/046790A1 |
The present invention relates to a method for producing lactones from optionally substituted, saturated aliphatic diols comprising 5 to 20 carbon atoms between both ring-closing hydroxyl groups by catalytic dehydration and cyclization in...
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WO/2008/026140A2 |
The invention relates to a malodor counteractancy or counteracting (MOC) method that resorts to the use of specific malodor counteracting (MOC) mixtures of fragrance ingredients. More particularly, the invention relates to new MOC compos...
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WO/2008/020830A1 |
A method of treating or reducing the probability of an Aspergillus or Cryptococcus infection in a subject in need of such treatment or reduction of probability, comprising administering to the subject a pharmaceutical composition compris...
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WO/2007/149543A2 |
A method for treating a scar comprises administering to a scar a pharmaceutically effective amount of one or more blistering agents in a pharmaceutically acceptable carrier.
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WO/2007/054429A1 |
A process is described for the production of an (E,Z)-10,11 ,12-pentadecen-15-olide isomer mixture, which process comprises the following step: partial isomerisation of (E1Z)-H - and/or (E,Z)-12-pentadecen-15-olide, such that the (E1Z)-(...
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WO/2006/046140A2 |
The present invention relates to a process for preparing a lactone. The process comprises the steps of reacting an aldehyde with an organic halide in a carbon chain extension reaction to form an alcohol compound comprising a functional g...
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WO/2006/043075A1 |
This invention relates to the selective oxidation of organic compounds. According to the invention organic compounds are selectively oxidized using a peracid or a source of peracid, a transition metal based heterogeneous catalysts and a ...
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WO/2006/007523A1 |
This invention relates to a process for catalytically hydrogenating a hydrogenatable precursor in contact with a hydrogen-containing gas and a hydrogenation catalyst comprising one or more active hydrogenation catalyst components on a su...
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WO/2005/103065A1 |
The present invention relates to new anthracycline derivatives and their use in cancer therapy and diagnosis. These anthracycline derivatives can be radiolabelled and used as an imaging agent in cancer diagnosis. The radiolabelled anthra...
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WO/2005/079471A2 |
A compound or groups of compounds, present in an active principle, derived from tunicates of the species Synoicum adareanum, as well as to pharmaceutical compositions comprising these compounds. Extracts from tunicates show selective tox...
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WO/2005/061481A1 |
The present invention relates to compounds having the structure (and pharmaceutically acceptable derivatives thereof) (I) wherein R,,-R4, Z, X, A-B, D-E, G-J, and K-L are as defined herein, the synthesis thereof and the use of these comp...
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WO/2005/058491A1 |
The invention relates to a catalyst provided in the form of an extrudate, which contains 5 to 85 % by weight of copper oxide and comprises, in the active material and as binders, the same oxidic carrier material. The invention also relat...
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WO/2005/051875A1 |
A homogeneous process for the hydrogenation of dicarboxylic acids and/or anhydrides in the presence of a catalyst comprising: (a) ruthenium, rhodium, iron, osmium or palladium; and (b) an organic phosphine; wherein the hydrogenation is c...
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WO/2005/035489A2 |
Processes for synthesizing a compound of Formula (I) are provided by reacting a compound of Formula (i) with a compound of Formula (xx).
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WO/2005/035519A1 |
The invention relates to a method for producing 1-hydroperoxy-16-oxabicyclo[10.4.0]hexadecane (DDP-OOH), according to which 13-oxabicyclo[10.4.0]hexadec-1(12)-ene (DDP) and hydrogen peroxide are reacted in a diluent in the presence of a ...
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WO/2005/014569A1 |
The present invention pertains to a novel process for the preparation of lactones by decomposition of a 1,2,4-trioxepane of formula (I) wherein, R is H or CH3, n is 1-14, Rx independently is any substituent on the ring structure, inclu...
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WO/2005/014565A2 |
The present invention relates to an improved process to prepare cis-3-dihydrocarbylmethano-5-hydrocarbyldihydro-furan-2-ones
. The present invention also relates to novel compositions of matter comprising enantiomerically pure cis-3-dihy...
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WO/2004/089923A1 |
The present invention pertains to a process for the carbonylation of an epoxide by reacting it with carbon monoxide in the presence of a catalyst system containing two components, wherein the first component is a source of one or more me...
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WO/2004/083170A2 |
Compounds of formula (1) wherein R1 is hydrogen, hydroxy, halogen, nitro, cyano, amino, carboxy, carboxylic ester, sulfo, sulfonic ester, carboxylic amide, sulfonic amide, alkoxy, aryloxy, alkylthio or arylthio, X is -0-, -S-, -NH- or -N...
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WO/2004/078738A1 |
The present invention relates to a process for the oxidation, in an inert solvent, of a non-aromatic or non-enonic ethylenic bond or of a non-conjugated cyclic ketones into the corresponding epoxides, respectively lactone, using H?2#191O...
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WO/2004/065402A1 |
The invention relates to derivatives of 9-ketospinosyn derivatives, which are substituted in the C-9 position by a radical =N-(O, NH or NRx)-Ry, to a method for the production thereof, and to their use for controlling animal pests.
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WO/2004/043592A1 |
The invention relates to a method for hydrogenation of carbonyl compounds, in particular C4-dicarboxylic acids for producing mixtures of tetrahydrofuranne and gamma-butyrolactone on supported rhenium-containing catalysts. Said catalysts ...
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WO/2004/037757A2 |
A process for production of tetrahydrofuran, gamma butyrolactone, 1,4 butanediol and the like from a hydrogenatable precursor such as maleic acid, succinic acid, corresponding esters and their mixtures and the like in an aqueous solution...
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WO/2004/035543A1 |
The invention relates to compounds of formula (I) wherein Rl, R2, R3, R4, R5, R6, R7 and R8 are as defined in the description, their use as medicament, pharmaceutical compositions containing them and processes for their preparation.
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WO/2004/033702A1 |
Microorganisms belonging to the genus Streptomyces and being capable of producing K99−5278A, K99−5278B and K99−5278C, which are drugs efficacious against infection with so−called fungi such as molds and yeasts, are cultured in a ...
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WO/2004/029033A1 |
A valerolactone compound represented by the formula (I): (I) (wherein R1 and R2 each independently represents hydrogen, methyl, or ethyl; R3 represents hydrogen or methyl; and R4 represents propyl, 1-propenyl, or phenyl; provided that no...
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WO/2004/020424A1 |
A process for preparing functionalized y-butyrolactones 3 and various biologically active compounds using mucohalic acid 1 and halide 2 in the presence of indium is disclosed, wherein X, Y, RI, R2, and R3 may have any of the meanings def...
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WO/2004/012861A1 |
The invention relates to the production of lactones by means of the catalytic carbonylation of oxiranes. According to the invention, a catalyst system containing a) at least one carbonylation catalyst A consisting of neutral or anionic t...
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WO/2004/007476A1 |
The invention relates to 5-thiapethilones and 15-disubstituted epothilones according to formula I (I) with the following meanings: X= >C = O or >S = O R1 = C1-6 alkyl or C2-6 alkenyl R2 = H or C1-6 alkyl Y - Z = >C=C< or >C-O-C< (epoxide...
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