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WO/2018/010932A1 |
The present invention relates to a method of reacting starting materials with an activating group, namely alkanes carrying a leaving group and/or olefins, with carbon dioxide under transition metal catalysis to give carboxyl group-contai...
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WO/2017/216498A1 |
The invention relates to the recovery of CO2 by using a reaction transforming an epoxide into cyclic carbonate using, as a catalyst, an amine of general formula (I) below or its tautomeric form. The invention also relates to the intermed...
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WO/2017/213226A1 |
Provided is a polymer compound which is changed from a water-insoluble state to a water-soluble state by irradiation with light. The polymer compound is represented by chemical formula (5), where: A and B each represent a single bond or ...
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WO/2017/207556A2 |
The invention relates to compounds which are suitable for treating bacterial diseases and to pharmaceutical compositions containing such compounds. The invention further relates to a kit of parts comprising such compounds and to the use ...
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WO/2017/204155A1 |
A method for producing an acetal compound, the method comprising: a step (A) for oxidizing a compound represented by general formula (1) (R1 represents an alkyl group having 1-6 carbon atoms) to obtain a compound represented by general f...
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WO/2017/204144A1 |
Provided is a method for amidating a hydroxy ester compound at a high chemical selectivity. The amidation reaction method for a hydroxy ester compound comprises, in the presence of a catalyst containing a compound of a transition metal o...
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WO/2017/205795A1 |
The invention relates to compounds that promote hematopoietic regeneration. The invention further relates to methods of promoting hematopoietic regeneration using the novel compounds of the invention.
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WO/2017/023774A9 |
Prodrugs of glutamine analogs, such as prodrugs of aza-serine, and 6-diazo-5-oxo-norleucine (DON), and 5-diazo-4-oxo-L-norvaline (L-DONV) are disclosed.
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WO/2017/197670A1 |
Disclosed in the present application is a method for synthesizing a 1,2-dimethylene cyclobutane chiral compound. The 1,2-dimethylene cyclobutane chiral compound is synthesized from an allenylamine compound in the presence of a rhodium co...
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WO/2017/193034A1 |
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.
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WO/2017/192304A1 |
The present disclosure is directed to compounds of formula (I): or a pharmaceutically acceptable salt, solvate or solvate of the salt thereof. Compounds of formula (I) are inhibitors of NOX4 and are useful in the treatment of fibrotic di...
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WO/2017/188551A1 |
The present invention relates to a novel N-acylurea derivative and use thereof in the treatment or prevention of cardiovascular diseases and, more particularly, to a novel N-acylurea derivative, a pharmaceutical composition comprising th...
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WO/2017/186846A1 |
The present invention refers to aryl beta diketones of the formula (I) wherein Y, R1, R2 and R3 have the same meaning as given in the description. The invention further refers to fragrance compositions and fragranced articles comprising ...
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WO/2017/182433A1 |
The present invention relates to novel hydroxamic acid derivatives as inhibitors of meprin β and/or α, pharmaceutical compositions comprising such compounds, methods for treatment or prophylaxis of diseases or conditions, especially su...
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WO/2017/178418A1 |
Processes for producing ethylene carbonate and/or ethylene glycol, and associated reaction systems are similarly provided. Specifically, a process is provided that comprises supplying an overhead absorber stream withdrawn from an absorbe...
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WO/2017/174827A1 |
The invention relates primarily to the use of one or more stereoisomers of compounds of formula (I) for modifying and/or intensifying the odour sensation of one or more aromas with a lily of the valley scent. The invention also relates t...
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WO/2017/176392A1 |
The invention provides a new convergent approach for the synthesis of 2'-fluoro-6'- methylene-carbocyclic adenosine (FMCA) and 2'-fluoro-6'-methylene-carbocyclic guanosine (FMCG) from a readily available starting material in eight steps....
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WO/2017/170884A1 |
Provided are: a novel method for producing a hydroxamic acid derivative, which uses, as an intermediate, a compound represented by general formula [12] (wherein R1 represents a methyl group, etc.; R2 represents a methyl group, etc.; and ...
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WO/2017/168313A1 |
The present invention provides an improved process for preparation of L-threo-(2S,3R)-3-(3.4- dihydroxyphenyl)serine (I) (Droxidopa) and its salts; comprising (a) reaction of the aldehyde compound (III) (as described herein) with Metal c...
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WO/2017/158404A1 |
This invention relates to an improved method for preparing alkylenedioxybenzene compounds of Formula I, from the corresponding ortho-dihydroxy aromatic compound of Formula II wherein n is 0, 1, 2 or 3; and R1 and R2 independently represe...
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WO/2017/153952A1 |
The invention is directed to substituted salicylamide derivatives. Specifically, the invention is directed to compounds according to Formula (I): wherein R, R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof. ...
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WO/2017/153950A1 |
The 4-hydroxyphenyl-2-oxoethyl carboxylic derivatives of the general formula: R1-A- R2, wherein the core A is: Formula (I) and R1 is phenyl substituted with two C1-C4 alkyl, 1,3-benzodioxolyl or bicyclo[3.3.1]nonanyl and R2 is H, hydroxy...
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WO/2017/140658A1 |
The present invention relates to a compound of formula (I) : wherein: - n is 1 or 2; Z1, Z2 and Z3, identical or different, are selected from a hydrogen atom, a halogen atom and a (C1-C6)alkyl group; and - R is an optionally substituted ...
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WO/2017/142028A1 |
A metal-supported macromolecule and a use thereof as a catalyst, said metal-supported macromolecule being obtained by causing a ligand to react with a zinc compound or a cobalt compound, said ligand having an imidazole group that is bond...
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WO/2017/134002A1 |
The invention relates to a method for producing (meth) acrylic acid esters with isomeric alcohols obtained by reacting glycerine with formaldehyde (hydroxy substituted dioxanes and dioxolanes) in high yield using catalysts based on titan...
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WO/2017/133424A1 |
The present invention relates to a preparation method of 1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-cyclopropanecarboxy
lic acid, wherein 2-(2-thiobenzo[D][1,3]dioxol-5-yl) acetonitrile is used as an intermediate, firstly the intermediate ...
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WO/2017/132014A1 |
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, compositions containing suc...
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WO/2017/129061A1 |
Disclosed is an application of substituted cinnamamide derivatives in the preparation of Anti-anxiety medications, the substituted cinnammide derivatives are compounds having the structure of formula (I) or pharmaceutically acceptable sa...
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WO/2017/132021A1 |
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, compositions containing suc...
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WO/2017/125759A1 |
This invention relates to aprocess for the preparation of glycerolcarbonate from the reaction of glycerol and a dialkylcarbonate, for example dimethyl carbonate, or a cyclic alkylene carbonate. More specifically, the invention relates to...
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WO/2017/113489A1 |
Provided in the present invention are ingenol compounds and a use thereof in preparing an anti-HIV latency drug. In particular, provided in the present invention is a use of ingenol compounds and pharmaceutically acceptable salts thereof...
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WO/2017/113964A1 |
Provided is a novel stilbene derivative, being a compound having the general formula (I) or general formula (II), or an acceptable salt formed from the compound having the general formula (I) or general formula (II) with an inorganic aci...
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WO/2017/107567A1 |
A method for treating atopic dermatitis in a subject in need thereof is provided. The method includes administering to the subject a composition containing a therapeutically effective amount of a melatonin associated compound and a pharm...
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WO/2017/111176A1 |
Synthesis of an organic compound with chirality is an important technique in the fields of medicines, pesticides, health foods, etc. However, catalysts to be used for such synthesis are produced from expensive starting materials and, fur...
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WO/2017/102701A1 |
Processes for reducing the amount of a gaseous iodide-containing impurity present in a recycle gas stream used in the production of ethylene oxide, in particular a vinyl iodide impurity, are provided. Processes for producing ethylene oxi...
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WO/2017/096559A1 |
The present invention relates to the production of xylene derivatives from furfural and its derivatives. The invention describes new routes for converting furfural and its derivatives into xylene derivatives including novel intermediates.
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WO/2017/093209A1 |
The present invention relates to a process for preparing 3-amino tetrahydropyrans and, more particularly, to an improved method for synthesizing a 2,3,5-substituted tetrahydropyran derivative, intermediate being used in the preparation o...
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WO/2017/085144A1 |
The invention relates to new compounds of formulae: Wherein: R 1 and R 2 can be independently H; a C 1 to C 6 alkyl including methyl, ethyl, propyl, butyl; aryl including phenyl, para-methoxyphenyl; or R 1, R 2 together with the carbon C...
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WO/2017/082936A1 |
A composition effective for removing solder fluxes either as a concentrated material or when diluted with water. The composition is effective in removing all types of solder fluxes including rosin type, resin type, no-clean, Sow residue,...
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WO/2017/078271A1 |
Disclosed herein is a colored photosensitive resin composition including a copolymer, an epoxy resin compound or a compound derived therefrom, a polymerizable compound, a photoinitiator, and a colorant, wherein the photoinitiator include...
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WO/2017/070084A1 |
The disclosed subject matter provides N- hydroxylsulfonamide derivative compounds of formulae (I), (II) or (III) as drawn below, pharmaceutical compositions comprising such compounds, kits comprising such compounds, and methods of using ...
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WO/2017/060418A1 |
The present invention provides novel cell-permeable carboxylic acid-based metabolites and cell permeable precursors thereof aimed at increasing ATP-production in mitochondria and thus, for use in medicine. The main part of ATP produced a...
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WO/2017/051363A1 |
The present invention relates in general terms to a new process for the preparation of organic carbonate derivatives, cyclic or linear by a trans carbonation reaction between PCC and a suitable aliphatic alcohol, in the presence of a hom...
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WO/2017/053793A1 |
Methods and systems for making intermediates in the synthesis of onapristone are provided. Aspects include the photoconversion of onapristone synthesis intermediates using a narrow band frequency light source.
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WO/2017/046816A2 |
The present invention relates to the process for preparing compounds of Formula I, Formula III and Formula V.
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WO/2017/040778A1 |
The invention provides compounds of Formula XXIII: (Formula XXIII) wherein R1 is hydrogen, alkyl, acyl, or silyl, R2 is hydrogen, alkyl, benzyl, acyl, or ester, and R3 is hydrogen, alkyl, an aromatic group, azacyclic, carbocycle, aryl, c...
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WO/2017/027388A1 |
Disclosed herein are the conversion of estolide compounds having unsaturated fatty acid groups into estolides containing cyclic carbonate moieties and methods of making and using the same. The estolides containing a cyclic carbonate may ...
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WO/2017/017696A1 |
The present disclosure relates to processes for the preparation of lumacaftor useful for treating a cystic fibrosis transmembrane conductance regulator (CFTR)-mediated disease such as cystic fibrosis. The present disclosure also provides...
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WO/2017/017210A1 |
The present invention concerns methods for the manufacture of ethylene carbonate substituted with a fluorinated alkoxy group, certain ethylene carbonates substituted with a fluorinated alkoxy group as well as their use as solvent or solv...
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WO/2017/009860A1 |
The anticancer activity of gallic acid compounds has been invented, in order to obtain new potent and cost effective molecule using in vitro cytotoxicity assay. The invention particularly relates to the gallic acid based new molecules i....
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