Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 8,036

Document Document Title
WO/2021/068950A1
Disclosed in the present invention are an amide compound and the medical use thereof as a STING inhibitor. Specifically, disclosed is a compound represented by formula I or formula II, or a pharmaceutically acceptable salt or ester or so...  
WO/2021/055849A1
The application relates to lipids of Formula (A-1) and compositions involving the same. Lipid nanoparticles (e.g., empty LNPs or loaded LNPs) include such a lipid as well as additional lipids such as phospholipids, structural lipids, and...  
WO/2021/028810A1
The present invention relates to certain compounds, their use in therapy, as well as to pharmaceutical compositions including said compounds. Specifically, the invention relates to certain compounds and pharmaceutical compositions includ...  
WO/2021/018834A1
The present invention relates to compounds of Formula (I), wherein R1, R2, R3, R4x, R4y, m, n and G are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use fo...  
WO/2021/020429A1
The present invention provides a compound represented by formula (I) or a pharmaceutically acceptable salt thereof which has the effect of antagonizing the LPA1 receptor.  
WO/2021/000054A1
The present disclosure relates to a carmabinoid derivative, a pharmaceutical composition comprising it, as well as its use in the treatment and prevention of diseases associated with a carmabinoid receptor in a subject in need thereof, s...  
WO/2020/253243A1
The present invention provides a process method for catalyzed synthesis of lactide with an alkali metal compound, comprising: mixing an alkali metal compound with a lactic acid oligomer, and carrying out a cracking reaction to obtain lac...  
WO/2020/253244A1
The present invention provides a process for the catalytic synthesis of lactide, comprising: mixing a lactic acid oligomer with a composite catalyst; and synthesizing lactide under a heating condition, and collecting the product using a ...  
WO/2020/255741A1
The present invention addresses the problem of providing: a hydrophilic metal-surface treatment agent which can impart water repellency to metal surfaces to inhibit the metals from corroding or discoloring; a method for treating a metal ...  
WO/2020/251745A1
Polylactide resin compositions that exhibit rapid hydrolysis rates and leave small amounts of residuals include a poly(meso-lactide) and a second polylactide. The polylactide resin compositions are useful in applications in which rapid h...  
WO/2020/244518A1
The present invention provides a compound with benzyloxy aromatic ring structure represented by general formula (I), a stereoisomer, enantiomer or pharmaceutically acceptable salt thereof, a preparation method thereof, a pharmaceutical c...  
WO/2020/239980A1
The present invention relates to an arthropod controlling composition comprising a compound according to formula (I), methods and uses to control arthropods as well as arthropod controlling articles comprising the same.  
WO/2020/230822A1
The present disclosure provides a method with which a fluorolactone compound can be produced in a single step from hexafluoropropylene oxide or the like. The present disclosure relates to a method for producing a compound represented by ...  
WO/2020/224396A1
Provided in the present invention are a class of compounds inhibiting TDG activity. In particular, provided in the present invention is a compound as shown in formula I and which has a new structure. The small-molecule inhibitor of the p...  
WO/2020/223536A1
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.  
WO/2020/209035A1
A compound represented by formula (1). R1 is, for example, an alkyl having 1-15 carbon atoms; ring A1 and ring A2 are 1,4-phenylene, etc.; a is 2, etc.; b and c are 0, 1, or 2; Z1 is a single bond, etc.; P1 and P2 are polymerizable group...  
WO/2020/193650A1
The invention relates to a new process for preparing a 1,2-endoperoxide compound of formula (I) as well as to products obtained by said process.  
WO/2020/184142A1
[Problem] To provide a compound which has high stability with respect to heat, high voltage holding ratio if used in a liquid crystal display element, and the like. [Solution] A compound which is represented by formula (1). In the formul...  
WO/2020/178053A1
Phenol derivatives of general formula (I) and (II), wherein meanings of the substituents are indicated in the description, their pharmaceutically acceptable salts, together with the processes for their preparation, their use as antimicro...  
WO/2020/173016A1
The present invention relates to a resorcinol dianisole derivative, wherein the chemical structure of this compound is as represented by the following formula (I). The compound of the present invention can inhibit the binding of programm...  
WO/2020/169770A1
The invention discloses a method for the preparation of fluoro alkylated 1,4-dioxene by homogene- ous Ni catalyzed fluoro alkylation with fluoro alkyl halides of 1,4-dioxane in the presence of a base.  
WO/2020/169768A1
The invention discloses a method for the preparation of fluoro alkylated compounds by homogeneous Ni catalyzed fluoro alkylation with fluoro alkyl halides in the presence of a base.  
WO/2020/166632A1
The present disclosure provides: a method which is capable of producing a fluorolactone compound from hexafluoropropylene oxide or the like by a single step; and the like. The present disclosure relates to a method for producing a comp...  
WO/2020/148619A1
The present invention relates to novel heterocyclic compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates...  
WO/2020/076274A3
The present invention is related to unique caffeic acid phenethyl ester (CAPE) analogues, methods for preparation of said molecules, and the usage of said unique molecules in the preparation of a pharmaceutical composition that is to be ...  
WO/2019/090085A8
Provided herein are compounds of formula (I), compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions. (Formula I).  
WO/2020/127924A1
The invention relates to a process for the preparation of Voxelotor, or a salt or solvate thereof, which comprises the use of a compound of formula (I) or (I'), or a salt or solvate thereof.  
WO/2020/124433A1
Provided herein is a process for preparing acetals or ketals by reacting Alcohol I, Alcohol II and oxygen in the presence of a metal-organic framework (MOF) catalyst.  
WO/2020/114905A1
According to the present invention a process is provided for producing glycolide which comprises contacting glycolaldehyde dimer with an oxidizing agent to produce a glycolide product.Preferably, the process is carried out in an aprotic ...  
WO/2020/106028A1
The present specification provides a compound represented by chemical formula 1 and an organic light-emitting device comprising same.  
WO/2020/087217A1
The invention relates to a process of preparing a glycolide product from methyl polyglycolate or its product. The process comprises depolymerizing the methyl polyglycolate or its product in the presence of a depolymerization agent to mak...  
WO/2020/087221A1
Provided is a process for producing a product having polyglycolic acid and glycolide from methyl glycolate. The process comprises esterification, polycondensation and optimization. Also provided are a product produced by the process and ...  
WO/2020/087223A1
The invention relates a novel polyglycolic acid. The polyglycolic acid comprises branched repeating units and linear repeating units. The polyglycolic acid may be produced from methyl glycolate by polycondensation in the presence of stru...  
WO/2020/092383A1
The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processe...  
WO/2020/086864A1
Described are positive allosteric modulators of muscarinic acetylcholine receptor M1 (mAChR M1), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating neurological disorders...  
WO/2020/081836A1
The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.  
WO/2020/064701A1
The present invention generally relates to the formation, chemistry and application of biologically active compositions. More particularly, the present invention relates to certain dyes, specifically porphyrin and chlorin derivatives, in...  
WO/2020/064818A1
Industrially viable and advantageous processes for the preparation of Ozanimod are described. The invention also discloses the intermediates obtained in the process.  
WO/2020/041927A2  
WO/2020/020365A1
The present invention involves a method for isolating, by means of salt formation and resolution, a single optically active N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxan-6-yl)-2-hydroxy-1- (1-pyrrolidinylmethyl)ethyl]octanamide as shown in f...  
WO/2020/009132A1
The present invention pertains to a novel method for producing diarylpyridine derivatives, the purpose of the present invention being to provide a industrially useful, novel method. A novel method for synthesizing pyridine rings without ...  
WO/2019/242687A1
The present invention discloses a 1,3-dioxane-4,6-dione compound, and a preparation method, a pharmaceutical composition, and an application thereof. The structure of the compound is represented by formula I, and the definition of each s...  
WO/2019/233474A1
The present disclosure relates to compounds with antiviral activity, methods for the preparation ofsuch compounds, and their use to inhibit viral nucleoprotein activity, viral transcription, replication, and assembly into the newly forme...  
WO/2019/211778A3
The present invention is directed to pro-drugs of Eliglustat (formula A) and process for the preparation thereof. The present invention is further directed to pharmaceutical composition thereof and method of treatment using the same.  
WO/2019/228994A1
This invention relates to oleic acid derivative comprising a hydrophobic part C17H33 linked to a particular polar head part "A", especially for use as a medicament, for instance, for the treatment of a disorder caused by the GPR120 recep...  
WO/2019/219210A1
The present invention relates to a process for producing an intramolecular diester of a hydroxycarboxylic acid, wherein in a first step a hydroxycarboxylic acid is polycondensed to form an oligomeric hydroxycarboxylic acid. This is follo...  
WO/2018/220020A3
The invention relates to resorcinol-derived compounds of formula (I) and also the salts thereof, the solvates thereof and the optical and/or geometrical isomers thereof, including enantiomers and diastereoisomers, the racemic mixtures th...  
WO/2019/185877A1
The invention relates to a method for the preparation of a 4,5-dihydroxyisoleucine derivative comprising the steps of asymmetric Claisen rearrangement of a Z-aminocrotyl-glycin ester and subsequent kinetic resolution of the product diast...  
WO/2019/191445A1
A process for producing a cyclic acetal is disclosed. According to the process, a formaldehyde source is combined with an aprotic compound and contacted with a heterogeneous catalyst which causes the formaldehyde source to convert into a...  
WO/2019/191189A1
The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disor...  

Matches 1 - 50 out of 8,036