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JP5173546B2 |
The present invention relates to a method of removing a silyl protecting group from an oligonucleotide, said method comprising the step of admixing the oligonucleotide with particular agents.
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JP5160046B2 |
An aminostyryl compound represented by Formula 1: The organic light emitting device using the aminostyryl compound exhibits low driving voltage and improved brightness, efficiency, and color purity.
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JP5138380B2 |
A method for increasing natural killer cell activity in an animal by feeding the animal lipoic acid in amounts of from about 10 mg to about 1000 mg per day.
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JP5140354B2 |
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JP2013018741A |
To provide a method for manufacturing an organic disulfide compound in a high yield by a simple means to give only one kind of an organic disulfide compound substantially without by-producing a monosulfide compound and a polysulfide comp...
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JP5128799B2 |
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JP5118502B2 |
Compounds I-III wherein U is CH, O, or S; Z is mono- or di-substituted carbon; R is (CH2)nCO2H, (CH2)nSO3H, (CH2)nPO3H2, (CH2)nNO2, CH(SCH3)3, esters; R1 is H, hydroxyalkyl, aminoalkyl, alkoxyalkyl; RR1 is O; n is 0-4; R2, R3 is H, hydro...
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JP5108198B2 |
The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agent...
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JP5110263B2 |
To provide a material having a high refractive index facilitating the easy control of a ring opening polymerization reaction. Discolsed is a cyclic thiocarbonate represented by formula (1), wherein X, Y and Z each independently represent...
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JP5092943B2 |
Provided is a polymer having a polystyrene reduced number average molecular weight of 10 3 -10 8 , and comprising a repeating unit of formula (1): wherein A 1 is a divalent group represented by -Z- or -Z-Z-, in which Z is an atomic group...
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JP5092769B2 |
Provided is a polymer having a polystyrene reduced number average molecular weight of 10 3 -10 8 , and comprising a repeating unit of formula (1): wherein A 1 is a divalent group represented by -Z- or -Z-Z-, in which Z is an atomic group...
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JP5084293B2 |
To provide an optical film that can be manufactured in a simple manufacturing process and has reverse wavelength dispersion of birefringence, and to provide a retardation plate comprising the optical film. The optical film, which has bee...
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JP5078487B2 |
To provide a material for an electroluminescent device with which a buffer layer is formed without using water as its solvent, unlike a conventional polymeric material used for the buffer layer; and to provide an electroluminecsent devic...
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JP5071108B2 |
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JP5061527B2 |
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JP5060036B2 |
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JP5037999B2 |
The invention relates to a process for the preparation of compounds having at least one -CF2O- bridge in the molecule, which comprises initially reacting a bis(alkylthio)carbenium salt with a compound containing at least one hydroxyl gro...
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JP5032461B2 |
Process for purifying thioctic acid in water comprising the following steps: a) dissolving the thioctic acid in an aqueous alkaline solution or alternatively dissolving a thioctic acid salt, if necessary adjusting the pH to alkaline valu...
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JP5022224B2 |
Fuels, especially hydrocarbon fuels, and lubricants, especially lubricating oils, contain a class of anti-corrosion, anti-wear, anti-fatigue, and extreme pressure additives that are derived from 1,3-dithiolane-2-thiones.
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JP5024599B2 |
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JP2012520342A |
The present invention is directed to methods for treating metabolic disorders with compounds that are conjugates. The conjugates of the present invention are comprised of salicylic acid, triflusal, diflusinal, salsalate, IMD-0354, ibupro...
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JP5021055B2 |
It is an object of the present invention to provide a novel mass spectrometry method which overcomes the conventional problems mentioned above, which can analyze at a high sensitivity and high accuracy a chemical reaction on a surface of...
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JP5011596B2 |
To provide a new diamine compound having a high sulfur content, becoming a raw material for producing a polyamic acid and an imidization polymer having a further higher refractive index. This diamine compound is expressed by formula (1)....
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JP4998258B2 |
The invention relates to a medicament for IBS, which comprises a dual antagonist for 5-HT 2B and 5-HT 7 receptors having selective binding affinities for 5-HT 2B and 5-HT 7 receptors. The pharmaceutical composition of the invention is us...
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JP4983343B2 |
To provide a material having a high refractive index which allows the easy control of a ring opening polymerization reaction. Disclosed is a cyclic thiocarbonate represented by formula (1), wherein X and Y each independently represents a...
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JP4975467B2 |
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JP4970340B2 |
The invention relates to a process for the preparation of compounds containing at least one -CF2-O- bridge in the molecule, in which a) an acid is added onto at least one ketene dithioketal, b) the resultant bis(alkylthio)carbenium salt ...
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JP4968830B2 |
To provide an optical material having a high refractive index and excellent transparency, hard to be oxidized in thermal curing and having little tinting. The invention relates to the radically polymerizable compound having a group repre...
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JP4964377B2 |
The invention relates to liquid-crystalline compounds of the formula I,and to liquid-crystalline media comprising at least one compound of the formula I and to electro-optical displays containing such a liquid-crystalline medium.
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JP4955911B2 |
The present invention relates to a method for preparing an isocyanate compound by introducing phosgene into an organic solvent solution of a carbonate of a corresponding amine compound and reacting the carbonate of the amine compound wit...
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JP4951226B2 |
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JP2012508165A |
The present invention concerns an enantiomer R of a compound of Formula (I), wherein X is —NH—R1 or of Formula (V) or (VI), R1 is —(CH2)n—R2, R2 is a linear, branched or cyclic C1C6 aliphatic group, —O—(CH2)n—CH3, —NH—C...
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JP4903155B2 |
2-cyclopenten-1-one oxime derivatives represented by Formula (I), or pharmaceutically acceptable salts thereof inhibit the production of TNF-α or PDE4, and therefore show therapeutic effect in inflammatory or immunological disorders med...
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JP4895478B2 |
There is disclosed the use of a composition prepared by sulfurization of a highly reactive polyisobutylene having at least 25% of a methylvinylidene isomer and wherein the polyisobutylene has a number average molecular weight in the rang...
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JP4892808B2 |
A process for the production of a fluorinated organic compound, characterized by fluorinating an organic compound having a hydrogen atoms using IF5; and a novel fluorination process for fluorinating an organic compound having a hydrogen ...
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JP4883178B2 |
Disclosed is a diurethane compound R 2 (SO 2 ) m (CH 2 ) n OCONH-R 1 -NHCOO(CH 2 ) n (SO 2 )R 2 produced by a method allowing a diamine compound H 2 NR 1 NH 2 to react with a chloroformate compound ClCOO(CH 2 ) n (SO 2 ) m R 2 or a metho...
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JP4869595B2 |
Halogenated S-alpha-aminoalkyl dithiocarboxylate, dithiocarbamate or di- or tri-thiocarbonate compounds (I) are new. Also new are S-gamma-aminoalkyl thiocarbamylsulfanyl compounds (II) and 1,2-diamines (VIII). Thiocarbonylsulfanyl compou...
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JP4859264B2 |
The invention relates to ionic compositions having a high ionic conductivity comprising a salt with a delocalized anionic charge.An ionic composition comprises a salt in solution in a solvent and has a conductivity of greater than 10-5 S...
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JP4853922B2 |
To provide a method for industrially, advantageously manufacturing an organic ultra-thin membrane (an LB membrane) which is improved in environment resistance and excellent in conductivity, through a simple process. The conductive organi...
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JP4849792B2 |
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JP4847314B2 |
Methods of inhibiting the cytokine or biological activity of Macrophage Migration Inhibitory Factor (MIF) comprising contacting MIF with a compound of formula (I) are provided. The invention also relates to methods of treating diseases o...
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JP4825412B2 |
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JP4822495B2 |
To provide a transparent resin material improved in heat resistance as a resin which is used for an optical element, and the like, having a high refractive index and a high Abbe's number. The transparent resin optical material is obtaine...
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JP4811573B2 |
A charge-transporting organic material containing a compound with a 1,4-dithiin ring, which is represented by the following formula (1), is described. When using a thin film made of such an organic material in a low-molecular-weight orga...
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JP4806538B2 |
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JP4808781B2 |
The present invention relates to derivatives of lipoic acid and skin external applications containing thereof that represent whitening effect, soothing effect, anti-aging effect and acne- improving effect and preventing effects of bladne...
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JP2011526895A |
The invention provides beta-sulfonamide alpha-keto esters and amides in which the alpha-keto is protected as a 1,3-dithiolane derivative. Also provided are methods for preparing such esters and amides and for incorporating them into pept...
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JP4792299B2 |
A photosensitive composition, which comprises a compound represented by formula (I): wherein R 1 to R 13 each independently represents a hydrogen atom or a substituent, and at least one of R 1 to R 13 is a substituent containing an alcoh...
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JP2011195516A |
To provide an anticancer agent by using a lipoic acid derivative as an active ingredient.This anticancer agent is provided by using a compound expressed by formula (1) [wherein, R1 is OH, O-alkyl, N-substituted amino, an amino acid resid...
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JP4782903B2 |
Ionic compound with low melting point has cation of the onium type with at least one heteroatom such as N, O, S or P; and anion which includes, wholly or partially, at least one imide ion. Independent claims are also included for: (1) el...
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