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Document Title |
JPH10509140A |
Pyrazole derivatives represented by formula (I) and physiologically acceptable salts thereof can suppress the production of both of prostaglandins and leukotrienes simultaneously, and, therefore, exhibit anti-inflammatory and analgesic e...
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JPH10508030A |
Antihyperglycemic compounds selected from the group consisting of C-substituted pentacycloazoles and N-alkyl-substituted pentacycloazoles.
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JP2766421B2 |
The present invention relates to a novel antibacterial compound of formula (I) from the genus Alteromonas and which shares structural similarity with the pseudomonic acids. i
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JP2764784B2 |
PURPOSE: To provide the subject compound having wide range of vermin controlling effect without giving chemical damage to a cultivated plant and useful as insecticide. CONSTITUTION: The compound is expressed by formula I [A is a 5-member...
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JP2761441B2 |
The present invention provides certain 3-aryl-5,6-dihydro-1,4,2-ocathiazines and their oxides, useful for the long-term preservation of wood and composite wood materials against wood damaging and wood destroying materials. The present in...
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JPH10504275A |
Compounds having the formulawhere R2 is a heteroaryl group linked to the remainder of the molecule via a carbon atom adjacent a nitrogen atom and R4 and R5 are both hydrogen atoms or together represent -SO- or -SO2- and A is C2-C4 alkyle...
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JPH1072444A |
To obtain the subject new compound useful as a medicine having a pharmacological activity such as a growth hormone accelerating activity. A benzene condensed lactam derivative expressed by formula I [R1 is a lower alkyl; R3 is H or a low...
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JP2695132B2 |
PURPOSE: To obtain a new inhibitor which inhibits DNA gyrase activity in bacteria, has antibiotic properties, especially antibacterial activity against microorganisms and is useful for treatment or prophylaxis of infectious diseases. CON...
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JPH09511215A |
Heteroarylpiperidines, pyrrolidines, and piperazines of the formula wherein X is -O-, -S-, -NH-, or -N(R 2 )- R 2 is selected from the group consisting of lower alkyl, aryl lower alkyl, aryl, cycloalkyl, aroyl, alkanoyl, alkoxycarbonyl a...
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JPH09221481A |
To obtain a medicine comprising a new specific aromatic compound, containing thiazolidine-2,4-dion-5-ylmethyl group, etc., and useful as a therapeutic agent, a preventing agent, etc., for insulin-resistance diseases, hyperglycemia, hyper...
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JP2645962B2 |
Compounds shown by the above formula or salt thereof show a strong angiotensin II antagonistic activity and hypotensive action and CNS activity, and are useful as therapeutic agents of circulatory diseases such as hypertensive diseases a...
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JP2614981B2 |
PURPOSE: To provide new compds. having low toxicity, useful for agonist of 5-HT1 like acceptor, such as antimigraine medicine, etc. CONSTITUTION: The compds. have formula I (where R1 is H, halogen, 1-6C alkyl, 1-6C alkoxy, cyano or the l...
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JP2609122B2 |
A silver halide photographic material containing a compound having a structure represented by formula (I) (I) wherein EAG represents a group capable of accepting an electron from a reducing material; E represents an electron-attracting g...
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JP2610988B2 |
Novel heterocyclic compounds of the formula (I) wherein A, R<1>, E, Z, X and Y have the meanings as defined in the patent application and the use of the new compounds as insecticides.
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JPH0881463A |
To obtain a novel compound that has activity against microorganisms, particularly Gram-positive bacteria, mycobacteria, anaerobic microorganisms and the like with low toxicity and is useful for prevention and treatment of systemic infect...
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JPH07121941B2 |
This invention relates to certain quinolinyl-benzoheterobicyclic compounds and their use as valuable pharmaceutical agents, particularly as lipoxygenase inhibitors and/or leukotriene antagonists and/or as mediator release inhibitors usef...
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JPH07113021B2 |
Compounds of formula I: in which R1, R2, R3, R4, R5, R6, R7, X, and n are defined in the description, their optical isomers and their addition salts with a pharmaceutically acceptable base or acid. ?>Medicinal products.
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JPH0791280B2 |
Aminobenzosultam derivatives as inhibitors of lipoxygenase and useful in the treatment or alleviation of allergic and inflammatory diseases.
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JPH07242664A |
PURPOSE: To obtain the subject novel compound having an antagonism against angiotensin II, useful for treatment of hypertension, aldosterone excessiveness, cardiac insufficiency, central nervous system diseases, or the like. CONSTITUTION...
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JPH0780998B2 |
Electrically conducting homo- and/or copolymers and/or tripolymers can be produced from novel monomers, such as a 3-substituted 2,5-di(2-thienyl)pyrrole. The polymers exhibit unexpectedly high stability and conductivities, and can be fun...
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JPH07173142A |
PURPOSE: To obtain the subject novel inhibitor which inhibits the angiotensinogen-cleaving action of a natural proteolytic enzyme, renin, and is useful in treating or preventing renin-associated hypertension, hyperaldosteronism, glaucoma...
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JPH0751564B2 |
Spirocyclic compounds of the formula: are oxytocin and vasopressin antagonists useful in the treatment of pre-term labor, dysmenorrhea and for the stoppage of labor preparatory to cesarean delivery, timing of parturition, uterine hyperac...
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JPH0699423B2 |
PCT No. PCT/US91/01470 Sec. 371 Date Nov. 6, 1992 Sec. 102(e) Date Nov. 6, 1992 PCT Filed Mar. 4, 1991 PCT Pub. No. WO91/17156 PCT Pub. Date Nov. 14, 1991.5-(1-Hydroxy-2-piperidinopropyl)-2(1H,3H)-indolone derivatives and analogs; pharma...
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JPH06329637A |
PURPOSE: To provide novel compounds useful as active compounds in medicaments, particularly as hypotensor and anti-artherosclerosis agents. CONSTITUTION: A compound of formula I [wherein A represents alkyl, alkenyl, or cycloalkyl; B repr...
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JPH0678339B2 |
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JPH06237790A |
PURPOSE: To obtain an enantiomer of a heterodicyclic alcohol by stereoselectively resolving from its corresponding racemic body through a specific process having no need of an optically active reagent, while converting another enantiomer...
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JPH06507418A |
Substituted 1-(2H)-isoquinolinones of the structural formula: (I) are angiotensin II antagonists which are useful in the treatment of hypertension and congestive heart failure.
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JPH06211654A |
PURPOSE: To obtain a new compd. having selective affinity for the 5-HT receptor of a brain and much smaller affinity for other receptor and useful to treat motion sickness and emesis. CONSTITUTION: This compd. is represented by formula 1...
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JPH06211655A |
PURPOSE: To obtain a new compd. having selective affinity for the 5-HT receptor of a brain and much smaller affinity for other receptor and useful to treat motion sickness and emesis. CONSTITUTION: This compd. is represented by formula 1...
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JPH0629248B2 |
(A) Bicyclic cpds. of formula (I) and their salts are new; where n = 0 or 1; m = 0-3; X = CH2, O, S, SO, SO2, NH or 1-4C alkylimino; X1 = CH2, O, S, SO or SO2; Y+Y1 = O, or Y = H and Y1 = OH or in-vivo hydrolysable acyloxy; Z = CH2, CHMe...
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JPH0656807A |
PURPOSE: To provide a new compd. which is effective to treat, prevent or control renin-associated hypertension, hyperaldosteronism, congestive heart failure and galucoma. CONSTITUTION: This compd., for example a compd. expressed by formu...
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JPH064624B2 |
Compound of the formula:- wherein R is phenyl or phenyl substituted by one or more substituents selected from nitro, halo, C1-C4 alkyl, C1-C4 alkoxy, aryl(C1-C4 alkoxy), C1-C4 alkylthio, C1-C4 alkylsulphonyl, hydroxy, trifluormethyl and ...
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JPH05320153A |
PURPOSE: To provide a new compd. useful as a prophylactic and therapeutic drug for diabetes and hyperglycemic obesity. CONSTITUTION: The compd. is expressed by formula I. In the formula I, R1, R4 are H, 1 to 4C alkyl, 1 to 4C alkoxy, etc...
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JPH05508167A |
Compounds of the formula II in which P is hydroxy and T is the group -X2-CR7aR7b-CHR8-OH or T is hydrogen and P is the group O-CHR8-CR7aR7b-X2-OH and, wherein X1, X2, R1, R2, R3, R4, R5, R6, R7a, R7b, and R8 are as defined in the specifi...
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JPH05222005A |
PURPOSE: To provide the subject compound which has the ability to inhibit angiotensinogen-cleaving action of the natural proteolytic enzyme, renin and is useful for preventing and treating renin-associated hypertension, hyperaldosteronis...
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JPH0552309B2 |
Compounds of the formulawherein C' and N4 are in trans configuration to each other, Y is OH, R'COO, R2R3NCOO- or R4O whereby R' is an aliphatic hydrocarbon residue having 1-17 carbon atoms, a phenyl, 2,6-dimethylphenyl or 3- or 4-hydroxy...
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JPH05155867A |
PURPOSE: To obtain a new substd. quinazolinone having angiotensin II antagonistic action which is useful for treatment of hypertension and congestive failure. CONSTITUTION: This compd. is a compd. of formula I [wherein L is bonded to J a...
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JPH04234881A |
PURPOSE: To provide a novel compd. which is excellent as a selective herbicide by treatments before germination and after germination. CONSTITUTION: This compd. is a triazolopyridine type one expressed by formula I (X, Y and Z are each H...
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JPH04128276A |
NEW MATERIAL:The compound of formula I [Z is A, group of formula II, CR2=N, etc., (A is O, S, SO, etc.; R2 and R3 are H, OH, halogen, etc.; R2 and R3 may be independently 3-6C cycloalkyl); R1 is H, 1-5C alkyl, alkanoyl or benzyl; (m) is ...
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JPH04500969A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPH0316951B2 |
Title compds. I [Het=aromatic heterocycle R1=H, alkyl, alkanoyl, R2=H, alkenyl, are prepd. Thus, 2-[5-(1-tertiany -butoxyformamide)- 3-(1,2,4-thiacliazolyl) -2-[[(Z)-(tertiarybutoxycarbonyl) methoxyl imino!acetate 2-benzthiazollyl thio e...
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JPH02229157A |
NEW MATERIAL:A compound of formula I [X is H, F; Z is formula II (R1 is 1-6C alkyl), formula III (R2, R3, R4 are 1-4C alkyl, N(CH3)2]. EXAMPLE: 2-[2-Chloro-4-fluoro-5-(4,5,6,7,2H-tetrahydroisoindole-1,3-d
ione-2-yl) phenyl-4-t-butyl-1,3,...
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JPH01305082A |
NEW MATERIAL: Compds. of formula I [wherein R1 is a (substd.) aliphatic, aromatic or alicyclic group; R2 is a (substd.) aliphatic group; and R3 is a (substd.) phenyl group united with a heterocyclic ring]. EXAMPLE: 1-(2,2-Dimethylpropyl)...
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JPS63284173A |
NEW MATERIAL:A benzothiazole derivative expressed by formula I [R is 2-(1- methyl)imidazolyl or formula IIWIV; R' is H, NH2, 1W4C alkyl or 1W4C alkylthio; n is 0, 1 or 2]. EXAMPLE: 2-[2'-(5'-Methyl-1',3',4'-thiadiazolyl)thio]benzothiazol...
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JPS6335632B2 |
A compound of the formula where R<6> is either wherein R' is (C1-C4)alkyl or phenyl; wherein W is hydrogen or halo, and n is 1 or 2; wherein Q is sulfur or oxygen; and V is hydrogen or (C1-C3)alkyl; or wherein Y is sulfur or oxygen; X is...
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JPS62226978A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPS61280491A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPS61212568A |
Fungicidally active novel piperazinylmethyl-1,2,4-triazolylmethyl-carbinols of the formula in which R represents optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkinyl, optionally substituted cycloal...
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JPS5980670A |
Disclosed are derivatives of 3-aryl-5,6-dihydro-1,4,2-oxathiazines and their oxides for use as herbicides, fungicides, plant dessicants and defoliants in agricultural and biocidal applications. Also disclosed are methods of making these ...
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JPS5839832B2 |
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