| Document |
Document Title |
|
JPH0435461B2 |
An improved process for preparing the antimicrobial compound flumequine is disclosed. The first step of the process comprises reacting 4-fluoroaniline with crotonaldehyde under acidic conditions at a temperature between 50 DEG and 60 DEG...
|
|
JPH04158084A |
PURPOSE: To improve the stability of a color-developing picture by using a specific compound as electron donative colorless dyes. CONSTITUTION: In a recording material utilizing color developing by the contact of electron donative colorl...
|
|
JPH04139184A |
PURPOSE: To obtain the title compound useful as an antimicrobial agent for livestocks by dissolving essence extracted from a specific plant with a lower alcohol into diluted hydrochloric acid, partitioning the solution with benzene and c...
|
|
JPH04136948A |
PURPOSE: To obtain a photosensitive body superior in mechanical characteristics by using a specified arylamine type compound as an organic type low-molecular- weight photoconductor. CONSTITUTION: The photosensitive layer formed on a cond...
|
|
JPH0416474B2 |
|
|
JPH0413341B2 |
|
|
JPH0412268B2 |
New compounds effective as antibacterial agent are disclosed. These new compounds include 8-[4-(4-aminobenzyl)-1-piperazinyl]-9-fluoro-6,7-dihydro-5-m
ethyl-1-ox o-1H,5H-benzo[ij]quinolizine-2-carboxylic acid, hydrates and acid addition ...
|
|
JPH04501122A |
The effects of acne and psoriasis are relived by applying either topically or by oral adminstration, a compound having the structure: wherein R1, R2, R3, R4 and R5 are independently selected from the group consisting of H, Cl, straight o...
|
|
JPH049786B2 |
This invention relates to novel heterocyclic carboxamides which increase the activity of the immune system and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds and...
|
|
JPH04500824A |
The effects of photoaging or sun damage of skin including loss of collagen fibers and deterioration of small blood vessels in the dermis of the skin are repaired by applying topically to the epidermis effective amounts of a compound havi...
|
|
JPH047727B2 |
|
|
JPH046706B2 |
|
|
JPH046707B2 |
|
|
JPH046723B2 |
A new class of sensitizers for photopolymerizable compositions is disclosed derived from cyclic ketones and tricyclic aminoaldehydes.
|
|
JPH045068B2 |
NEW MATERIAL:A compound shown by formula I[R<1> is 1-8C alkyl; R<2> is 1-8C alkyl, 5-7C cycloalkyl, (Cl-, Br- or 1-4C alkyl-substituted)benzyl or phenyl; X<1> and X<2> are 1-8C alkyl, 1-8C alkoxy, F, Cl or Br; m and n are 0-3]. EXAMPLE:3...
|
|
JPH0477B2 |
|
|
JPH0375541B2 |
|
|
JPH03261784A |
PURPOSE: To obtain the subject high-purity compounds useful as a synthetic intermediate for producing bisisoquinoline alkaloids in high yield by reacting an enamide in the presence of a radical former and tri-n-butylstannane in a solvent...
|
|
JPH0368032B2 |
NEW MATERIAL:The compound of formula I [R<1> is methyl or ethyl; R<2> is H, OH, lower alkyl or group of formula II (R<5> and R<6> are H, methyl or ethyl; n is 0 or 1); R<3> is H, lower alkyl or halogen; R<4> is H or lower alkyl; X is hal...
|
|
JPH0342279B2 |
|
|
JPH03148277A |
NEW MATERIAL: A compound of the formula [R1 and R2 are each C1-10 alkyl; R3 is H with cis- or trans-configuration; R4 is NHCOR' with cis- or trans- configuration (R' is C1-10 alkyl, phenyl, etc.), fused phenylcycloalkyl or benzofuranyl] ...
|
|
JPH03123780A |
NEW MATERIAL:A compound of formula I (R is H or 1-5C acyl). EXAMPLE: (4R, 6R, 11aR)-6-acetoxymethyl-4-cyano-7-methoxy-1,3,4,6,11a- hexahydro-2H-benzo[b]quinolidine. USE: Carcinostatics. PREPARATION: Firstly, 2-bromo-1-methyl-3-methoxyben...
|
|
JPH0395116A |
PURPOSE: To provide a reverse transcriptase-inhibiting composition exhibiting a reverse transcriptase-inhibiting activity and useful for inhibiting the multiplication of retro virus by containing a protoberberine type alkaloid. CONSTITUT...
|
|
JPH0322861B2 |
1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE Fluorinated aniline derivatives of the formula : see diagramm : EP0161482,P11,F1 wherein R**1 = H or (CH2 )n -X, wherein n = a whole number of 1 to 3, X = H, O...
|
|
JPH0321031B2 |
Benzo-heterocyclic compounds of the formula: (1) wherein R1 is a lower alkyl group; R2 is a halogen atom or a group of the formula (wherein R4 and R5 combine together with the nitrogen atom to which they bind to form a 5- or 6-membered s...
|
|
JPH039088B2 |
A compound of the formula: wherein R<1> is carboxy, amidated carboxy, cyano, thiocarbamoyl or tetrazolyl group; R<7> is hydrogen or aryl; R<2> is hydrogen, hydroxy, lower alkyl or lower alkoxy; R3 is hydrogen, hydroxyl, lower alkyl, lowe...
|
|
JPH039087B2 |
|
|
JPH039113B2 |
A compound of the formula: wherein R<1> is carboxy, amidated carboxy, cyano, thiocarbamoyl or tetrazolyl group; R<7> is hydrogen or aryl; R<2> is hydrogen, hydroxy, lower alkyl or lower alkoxy; R3 is hydrogen, hydroxyl, lower alkyl, lowe...
|
|
JPH037674B2 |
NEW MATERIAL:A compound shown by the formula I(A is methylene and B is carbonyl when AB bond is single bond and A and B form vinylene when AB bond is double bond; R<1> is H, 1-3C alkyl or 2-hydroxyethyl; R<2> and R<3> are H, methyl or et...
|
|
JPH036150B2 |
|
|
JPH0314578A |
NEW MATERIAL: Compounds of formula I {Q is formula II [A1 is N or CR7 (R7 is H, a halogen, alkyl, etc.); A2 is N or CR2 (R2 is H or a halogen); A3 is N or CH; R1 is H or R15 (R15 is an alkyl, carbon ring, etc.); R3 is H, a halo gen, etc....
|
|
JPH032868B2 |
1,2,3,4,4a,4b,5,6,7,8,8a,12b-Dodecahydro-7-(oxo, hydroxy or amino)-9-hydroxy-11-(alkyl, alkoxy or alkoxyalkyl)triphenylenes, 2,3,3a,3b,4,5,6,7,7a,11b-decahydro-6-(oxo, hydroxy or amino)-8-hydroxy-10-(alkyl, alkoxy or alkoxyalkyl)-1H-cycl...
|
|
JPH037260A |
NEW MATERIAL:A compound expressed by formula I [R1 is lower alkyl, cycloalkyl, etc.; R2 is H or carboxy-protecting group; R3 is H, halogen, amino, etc.; X is H or halogen; Y is N or C-R4 (R4 is H, halogen, etc.); Z is O or N-R5 (R5 is H,...
|
|
JPH0260653B2 |
Tricyclic benzo fused compounds of the formula (I) and pharmaceutically acceptable cationic and acid addition salts thereof, wherein n is zero, 1 or 2, and t is 1 or 2; M is CH or N, R1 is H or certain acyl groups; Q is CO2R4, COR5, C(OR...
|
|
JPH0256358B2 |
Benzoquinolizine derivatives of formula (I) (I) wherein: X1 represents a hydrogen atom or a halogen atom, R1 represents a cyclic amino group which may contain additional hetero atom(s) of N,S and O and may be substituted with one or more...
|
|
JPH02288880A |
PURPOSE: To provide a medicine containing quinolizine and a quinolizine deriv. as an effective component and useful for treating anxiety, a mental disease, glaucoma, the motional stimulation of the stomach, migraine, nausea and vomiting....
|
|
JPH02215784A |
PURPOSE: To obtain an alkaloid useful for treating asthma, bronchitis, shigellosis, etc., by grinding a plant material, slurring it in a mixture of water, a water- immiscible nonpolar solvent and the like at a specific pH to dissolve the...
|
|
JPH0236580B2 |
1,2,3,4,4a,4b,5,6,7,8,8a,12b-Dodecahydro-7-(oxo, hydroxy or amino)-9-hydroxy-11-(alkyl, alkoxy or alkoxyalkyl)triphenylenes, 2,3,3a,3b,4,5,6,7,7a,11b-decahydro-6-(oxo, hydroxy or amino)-8-hydroxy-10-(alkyl, alkoxy or alkoxyalkyl)-1H-cycl...
|
|
JPH0231054B2 |
|
|
JPH0222074B2 |
NEW MATERIAL:A compound shown by the formulaI(R<1> is H, lower alkyl; R<2> is H, halogen; R<3> is 1-pyrrolidinyl, morpholino, thiomorpholino, 1,2,5,6-tetrahydro- 1-pyridyl, etc.) and its salt. EXAMPLE:9-(1-Pyrrolidinyl)-8-fluoro-2-methyl...
|
|
JPH02115175A |
NEW MATERIAL: A compound of formula I [wherein R1 is H, a (substituted) 1-21C aliphatic group, a (substituted) 3-20C alicyclic group, a 7-32C araliphatic group or the like; R2 is R1 or the like; R3 is H, a (substituted) 1-21C aliphatic g...
|
|
JPH0217562B2 |
|
|
JPH02101076A |
PURPOSE: To obtain the subject compound useful as medicines in simple operation by extracting a protoberberine-based alkaloid-containing plant with water or a hydrophilic organic solvent, and subjecting the resultant extract to column ch...
|
|
JPH027314B2 |
Pyridobenzoxazine derivatives of formula (I) (I) wherein: X1 represents a hydrogen atom or a halogen atom, R1 represents a cyclic amino group which may contain additional hetero atom(s) of N,S and O and may be substituted with one or mor...
|
|
JPH01313477A |
PURPOSE: To obtain the title substance without using an expensive reagent by reacting endo-5-hydroxy-8-azatricyclo [5,3,1,03.8] undecan-10-one with mixed anhydride of trifluoroacetic acid and indole-3-carboxylic acid. CONSTITUTION: A com...
|
|
JPH01287027A |
PURPOSE: To obtain an injection having high stability and concentration, storable at room temperature or in cooled state without precipitating crystals, resistant to decomposition even at room temperature over a long period and compatibl...
|
|
JPH0154344B2 |
|
|
JPH01272581A |
PURPOSE: To obtain the subject compound useful for remedy of chronic hepatitis, nephrotic syndrome, etc., in good recovery by extracting a phellodendron with alcohols, dissolving the extract in water, shaking with a water-insoluble solve...
|
|
JPH01250380A |
NEW MATERIAL:The (+)-isomer of the optically active compound of formula I (X1 is halogen; R1 and R2 are lower alkyl), its salt or their hydrate. EXAMPLE: (+)-9-Fluoro-5-methyl-8-(4-methyl-1-piperazinyl)-6,7-dihydro
-1,7-dioxo-1 H,5H-benz...
|
|
JPH01226818A |
PURPOSE: To provide a learning-promoting agent or a mnemonic agent comprising an arylamidoazabicycloalkane and capable of promoting memory of living animals and useful for curing hypomnesia and dysmnesia. CONSTITUTION: This mnemonic agen...
|
