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Matches 251 - 300 out of 1,387

Document Document Title
WO/2001/079199A1
Acetylene derivatives represented by the general formula (I); and herbicides containing the derivatives and/or salts thereof as the active ingredient. In said formula R?1¿ to R?6¿, X?1¿, Y, Z and q are each as defined in the descripti...  
WO/2001/079204A1
The invention relates to novel compounds of the formula (I) wherein W, X, Y, Z, G, A, B, Q?1¿, Q?2¿ and D are defined as per the description, to several methods for the production of said compounds and to their use as pesticides and he...  
WO/2001/070734A2
The present application describes novel β-amino acid derivatives of formula (I) or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, X, Z, U?a�, X?a�, Y?a�, Z?a�, R?1�, R?2�, R?3�, R?4�, and R?4a� a...  
WO/2001/070739A1
The invention concerns compounds of general formula (I) wherein: X represents a hydrogen or halogen atom or an alkyl, alkoxy or trifluoromethyl group; and R represents either a hydrogen atom or an alkyl, cycloalkylmethyl, phenylmethyl gr...  
WO/2001/042218A1
Quinoline derivatives represented by formula (1) wherein two or more of substituents R¿1 ?to R¿7? are each a group of formula (2). It is preferable that among the substituents R¿1? to R¿7?, at least one of the substituents other than...  
WO2000008020A8
Compounds of formula (I) or salt thereof or solvate thereof, in which: m is 1 or 2; n is 1 or 2; X is CH or N; Y is selected from hydrogen, halogen, cyano, CF3, alkyl or alkoxy; R<1>, which may be at any position within the saturated rin...  
WO/2001/029035A1
4-Oxoquinolizine antimicrobials having 2-pyridone skeletons as the partial structure and exhibiting potent antimicrobial activities against gram-positive or -negative bacteria or anaerobic bacteria, which are compounds represented by gen...  
WO2000068229A3
The present invention relates to S-(-)-optically pure benzoquinolizine carboxylic acid of formula I, and their pharmaceutically acceptable salts, derivatives, pseudopolymorphs, and hydrates, substantially free of their R-(+)-isomers, to ...  
WO/2000/068229A2
The present invention relates to S-(-)-optically pure benzoquinolizine carboxylic acid of formula I, and their pharmaceutically acceptable salts, derivatives, pseudopolymorphs, and hydrates, substantially free of their R-(+)-isomers, to ...  
WO2000042045A3
The present invention is a novel series of functionalized heterocycles as chemokine receptor modulators of Formula (I) useful as modulators of chemokine receptor activity. The compounds are useful in the treatment and prevention of the A...  
WO/2000/066522A1
The present invention provides non-steroidal compounds of formula (I) which are selective modulators (i.e., agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides p...  
WO/2000/046223A1
Tricyclic quinolonecarboxylic acid derivatives represented by general formula (I) or salts thereof which are useful as remedies for skin infectious diseases, etc. showing a potent antibacterial effect on gram-positive and gram-negative b...  
WO/2000/042045A2
The present invention is a novel series of functionalized heterocycles as chemokine receptor modulators of Formula (I) useful as modulators of chemokine receptor activity. The compounds are useful in the treatment and prevention of the A...  
WO2000008020A3
Compounds of formula (I) or salt thereof or solvate thereof, in which: m is 1 or 2; n is 1 or 2; X is CH or N; Y is selected from hydrogen, halogen, cyano, CF3, alkyl or alkoxy; R<1>, which may be at any position within the saturated rin...  
WO/2000/037468A1
The present invention provides a 5,6-dihydrodibenzo[a,g]quinolizinium derivative and the salts thereof of formula (I) which specifically inhibits the sterol 14-reductase which is involved in the distal pathway of cholesterol biosynthesis...  
WO2000006173A8
The present invention relates to a compound of formula (I); or a pharmaceutical acid addition salt thereof; which are useful for activating 5-HT1F receptors and inhibiting neuronal protein extravasation in a mammal.  
WO/2000/017197A1
The present invention comprises novel compounds that are effective inhibitors of integrins, particularly $g(a)¿IIb?$g(b)¿3? or $g(a)¿v? integrins such as $g(a)¿v?$g(b)¿3? and $g(a)¿v?$g(b)¿5?. The present invention, according to o...  
WO/2000/008022A1
Compound of formula (I) or salts thereof or solvates thereof, in which, P is a single bond, methylene or ethylene; Q is hydrogen or C1-6alkyl; T is hydrogen; or Q and T together are -(CH¿2?)¿m?- wherein the saturated ring formed thereb...  
WO/2000/008019A1
The present invention refers to a process for the preparation of (1$i(H))-benzo[c]quinolizin-3-ones derivatives of general formula (I) which involves only three steps and the use, as starting products, of commercially available, or easil...  
WO/2000/008020A2
Compounds of formula (I) or salt thereof or solvate thereof, in which: m is 1 or 2; n is 1 or 2; X is CH or N; Y is selected from hydrogen, halogen, cyano, CF¿3?, alkyl or alkoxy; R?1¿, which may be at any position within the saturated...  
WO/2000/006572A1
Benzoquinolizine derivatives having tachykinin antagonism, in particular, substance P receptor antagonism. Namely, benzoquinolizine derivatives represented by general formula (1) and salts thereof and medicinal compositions containing th...  
WO/2000/006173A1
The present invention relates to a compound of formula (I); or a pharmaceutical acid addition salt thereof; which are useful for activating 5-HT¿1F? receptors and inhibiting neuronal protein extravasation in a mammal.  
WO/2000/004905A1
Benzo[$i(b)]quinolizidine and benzo[$i(f)]indolizidine derivatives are provided which are useful for the treatment of Alzheimer's disease, senile dementia, or other conditions characterized by memory loss. Pharmaceutical compositions con...  
WO/2000/004900A1
The present invention concerns antiviral compounds, their compositions, and use in the treatment of viral infections. More particularly, the invention provides benzimidazole derivatives for the treatment of respiratory syncytial virus in...  
WO/2000/003990A1
The invention concerns a pharmaceutical composition having an activity on the proliferation of clonogenic cells in tumours and comprising an efficient amount of a compound selected among the compounds of formulae (I) and (Ia) wherein: X,...  
WO/2000/004019A1
Described herein are compounds selective for a 5-HT¿1D? receptor, which have general formula (I) wherein: R?1¿ is selected from the group consisting of CR?5¿R?6¿CH¿2?NR?7¿R?8¿ and a group of formula (II) or (III) wherein R?2¿ is ...  
WO/2000/000487A1
The present invention relates to a compound of formula (I): or a pharmaceutical acid addition salt thereof; which is useful for activating 5-HT¿1F? receptors and inhibiting neuronal protein extravasation in a mammal.  
WO/1999/055704A1
The novel compounds of chemical formulae (I) and (II) exhibit $i(in vitro) antifungal activity against fungi including cutaneous filamentous fungus, such as $i(Epidermophyton, Microsporum, Trichophyton, Sporothrix schenckii, Aspergillus)...  
WO/1999/047521A1
The present invention concerns derivatives of general formula I (I' and I''), in which X represents a divalent radical of formula (a) or (b), R¿1?, R¿2?, R¿3?, and R¿4? represent, independently of each other, a hydrogen atom, a hydro...  
WO/1999/044987A1
Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are of general formula (I), where X¿1?, X¿2?, Y, and Z are defined variables. Such compounds and their pharmaceutically acceptable salts, multim...  
WO/1999/033828A1
The present invention refers to benzo[c]quinolizines derivatives, fully and partially saturated, having formula (I), and their pharmaceutically acceptable salts which proves useful for pharmaceutical and agricultural use being capable of...  
WO/1999/032480A1
Novel compounds having formulas (I), (II) or (III) or pharmaceutically-acceptable salts or prodrugs thereof, which are useful for controlling synaptic transmission; to therapeutically-effective pharmaceutical compositions of these compou...  
WO/1999/021855A1
Derivatives of pleuromutilin of formula (IA) or (IB) in which the glycolic ester moiety at position (14) is replaced by R?2¿(CH¿2?)¿m?X(CH¿2?)¿n?CH¿2?COO are of use in antimicrobial therapy. In which: each of n and m is independent...  
WO/1999/021856A1
The invention concerns 2-aminomethyl-benzo[a]quinolizidine derivatives, corresponding to general formula (I) in which: R¿1? represents either a hydrogen atom or a branched, linear or cyclic C¿1?-C¿4? alkyl group, a branched, linear or...  
WO/1999/011627A1
The invention relates to benzimidazole antibacterial compounds of formula (I) as described herein, pharmaceutical compositions containing the compounds, and methods for their production and use. These compounds are effective in inhibitin...  
WO/1999/007696A1
A quinolizine carboxylic acid derivative of formula (I) or a pharmaceutically acceptable salt thereof, wherein R?1¿ and R?2¿ have the same meanings as defined in the specification.  
WO/1999/005913A1
Described herein is the use of benzo[c]quinolizine derivatives of formula (I) as regulators of the growth of plants, and compositions for agricultural use containing the said derivatives or their salts.  
WO/1998/046570A1
This invention provides novel 5-HT�1F? agonists of Formula (I) in which X, Y, E, R, A, B, and n are as defined in the specification, which are useful for the treatment of migraine and associated disorders.  
WO/1998/042667A1
Compounds of general formula (1), tautomers, stereoisomers and optical isomers of them, and medicinally acceptable salts thereof, which exhibit excellent inhibitory activities against nNOS or iNOS, and therefore are useful as remedies fo...  
WO/1998/040383A1
This invention concerns compounds of formula (I), the pharmaceutically acceptable acid additions salts and the stereochemically isomeric forms thereof, wherein the dotted line represents an optional bond; X is oxygen or sulfur; -A- is a ...  
WO/1998/038191A1
A process for the preparation of a compound having formula (a) wherein R?1�, R?2�, R?3�, R?4�, and R?5� are defined, from an enamine by chain expansion and ring closure followed by additional derivatization, treatment with a 3-...  
WO1998025930A3  
WO/1998/025930A2
The invention is concerned with the use of bi- and tricyclic pyridone compounds of general formula (I) and of their pharmaceutically acceptable salts for the production of medicaments for the prophylaxis or treatment of illnesses which a...  
WO/1998/022437A1
A process for the preparation of chiral 3-aminopyrrolidine of formula (I) and analogous bicyclic derivatives of formula (II) from dihydroxy olefins such as for the formula: HO-CH�2?-CH=CH-CH�2?-OAr by treatment with titanium isopropo...  
WO/1998/018783A1
Compounds represented by general formula (I) carrying a tricylic amine substituent optionally having various substituents, their salts, hydrates thereof or drugs containing these compounds as the active ingredient. Because of having favo...  
WO/1998/007695A1
The present invention relates to organic molecules capable of modulating, regulating and/or inhibiting protein kinase signal transduction. Such compounds are useful for the treatment of diseases related to unregulated protein kinase sign...  
WO/1998/005642A1
CFTR channel activator compounds from the benzo[c]quinolizinium family or families of compounds derived therefrom, as well as pharmaceutical compositions containing said compounds, and the uses thereof, particularly for treating cystic f...  
WO/1998/005659A1
Compounds of formula (3), and pharmaceutically acceptable salts and derivatives thereof, in which R?1� is vinyl or ethyl; and R?2� is a group R?3�, R?4�CH�2?-, or R?5�R?6�C=CH-; wherein each of R?3� and R?4� is an azabi...  
WO/1998/004937A1
The invention relates to photochromic compounds of general formula (I), in which: R1-R8 represent various substituents, characterized in that at least two of the groups R3-R6 are C1-C6 alkoxy groups.  
WO/1998/001443A1
A compound of formula (I), or a salt thereof, or a solvate thereof, wherein Ra represents a group R�5? which is hydrogen, alkyl or optionally substituted aryl and Rb represents a moiety of formula (a), wherein X represents a hydroxy or...  

Matches 251 - 300 out of 1,387