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WO/2019/097101A1 |
The present invention describes a new method for functionalising proteins by incorporating a metal fragment of high-performance rhenium, thus producing coordinated iminopyridines having three carbonyl groups in the fac position which pro...
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WO/2019/091898A1 |
The present invention relates to a process for preparing 5-substituted imidazole compounds of formula (I), by reacting a ketone of formula (II) (II), and a manganese compound of formula (III), (III), wherein R1, R2, R3, R4, R5, Q, X, Y, ...
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WO/2019/039509A1 |
A composition comprising: a substance (A) (excluding a metal-organic framework) comprising atoms of at least one metal selected from the group consisting of zinc, cobalt, niobium, zirconium, cadmium, copper, nickel, chromium, vanadium, t...
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WO/2019/027059A1 |
The purpose of the present invention is to produce a radiolabeled aryl compound by a simple method in which labeling can be carried out in a short time in high radiochemical yield and which renders the radiolabeled aryl compound usable i...
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WO/2019/007664A1 |
The invention relates to an N-heterocyclic carbene (NHC) Re(I) complex having an unsubstituted or substituted benzimidazol-2-ylidene ligand and the use thereof, in particular in a pharmaceutical composition, as a medication and for treat...
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WO/2018/227977A1 |
Disclosed are a 99mTc-labelled isonitrile-containing glucose derivative of the structural general formula [99mTc-(CNDG)6]+ and a preparation method and the use. The derivative takes 99mTc+ as a central core, and the isonitrile carbon ato...
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WO/2018/225466A1 |
Provided are: a curing accelerator for an oxidatively polymerized unsaturated resin, having high curing acceleration characteristics; and a printing ink and paint using same. Specifically, provided are: a curing accelerator for an oxidat...
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WO/2018/192686A1 |
The invention relates to a method for producing, amongst other things, amino-acid and/or hydroxycarboxylic-acid metal chelates, a solvent-free mixture of at least one metal oxide, metal hydroxide, metal carbonate or oxalate, and the soli...
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WO/2018/189060A1 |
The invention comprises novel chiral metal complex compounds of the formula (I) wherein M, PR2, R3 and R4 are outlined in the description, its stereoisomers, in the form as a neutral complex or a complex cation with a suitable counter io...
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WO/2018/170553A1 |
This invention provides rhenium tricarbonyl complexes and their use in the treatment of cancer and inhibition of Aurora kinase. The rhenium tricarbonyl complexes comprise a C-donor N-heterocyclic carbene (NHC) ligand. Also provided are p...
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WO/2018/153333A1 |
The present invention provides a biflavonoid-manganese complex and a preparation method and application thereof. The present invention uses amentoflavone as a ligand and a manganese ion as a central ion for reaction to obtain an amentofl...
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WO/2018/121465A1 |
Diphosphino metallic complexes, methods of making and using are described. The complexes display cytotoxicity against a panel of cancer cell lines, and optionally display luminescent properties. They have improved solubility and are stab...
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WO/2018/115314A1 |
The invention provides compounds of formula (I) representing a polyaza-macrocycle with carboxylic acid side arms complexing Manganese as core metal. The complexes are suitable for use as contrast agents in magnetic resonance imaging (MRI).
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WO/2018/107526A1 |
The invention provides a method for preparing a tricarbonyl technetium-99m intermediate. The method comprises reacting a carbonyl manganese compound used as a carbon monoxide donor with pertechnetate and water to obtain the tricarbonyl t...
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WO/2018/109164A1 |
The present invention relates to a labeling procedure for the incorporation, in mild reaction conditions, of sensitive and thermosensitive targeting molecules into a [99m Tc(N)(PNP)]-based compound suitable for a kit formulation.
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WO/2018/046391A1 |
Metal complexes containing substituted allyl ligands and methods of using such metal complexes to prepare metal-containing films are provided.
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WO/2018/028312A1 |
A method of preparing luminescent nano-sheets includes preparing a precursor emulsion solution containing a metal halide and RNH 3X, with the molar ratio of metal halide to RNH 3X in a range of approximately 0.6 to approximately 0.8; dem...
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WO/2018/000984A1 |
A manganese (II) complex, a preparation method therefor and an application thereof, a structure of the complex being: (R1 R2 R 3 R4 A)2[MnX4], wherein, R1, R2, R3 and R4 are identical or different, and are independently selected from alk...
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WO/2017/223428A1 |
A composition comprising the following structure: (formula I) wherein Re represents a rhenium ion having a +1 charge; (formula II) represents an uncharged bidentate bicyclic ligand bonded to the rhenium (Re) by two ring nitrogen (N) atom...
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WO/2017/222362A1 |
The invention relates to a novel radiopharmaceutical that inhibits the prostate-specific membrane antigen (iPSMA), containing hydrazinonicotinamide (HYNIC) as a critical chemical group in increasing in the lipophilicity of the molecule f...
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WO/2017/180136A1 |
Provided herein are cross-linked graphene platelet polymers, compositions thereof, filtration devices comprising the cross-linked graphene platelet polymers and/or compositions thereof and method is using and making the same.
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WO/2017/137984A1 |
The present invention relates to novel manganese complexes and their use, inter alia, for homogeneous catalysis in (1) the preparation of imine by dehydrogenative coupling of an alcohol and amine; (2) C-C coupling in Michael addition rea...
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WO/2017/093283A1 |
The present invention is in the field of processes for the generation of thin inorganic films on substrates, in particular atomic layer deposition processes. The present invention relates to a process comprising bringing a compound of ge...
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WO/2017/089230A1 |
The present invention is in the field of processes for the generation of thin inorganic films on substrates, in particular atomic layer deposition processes. The present invention relates to a process comprising bringing a compound of ge...
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WO/2017/059130A2 |
The disclosure provides for diamine-appended metal-organic frameworks (MOFs), methods of making thereof, and methods of use thereof.
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WO/2017/027728A9 |
Aspects of the present disclosure relate to compounds which have enhanced oral bioavailability. A transition metal complex includes a transition metal coordinated by a macrocycle comprising the pentaaza 15-membered macrocyclic ring corre...
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WO/2017/050970A1 |
The present invention relates to highly efficient Nrf2 activators-CO-releasing molecules of formula (I) and (II) capable of increasing HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic ...
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WO/2017/031173A1 |
Disclosed herein are novel amine-functionalized porphyrin compounds, as wells as pharmaceutically acceptable salts or esters thereof. The disclosed compounds can be used to impart antioxidant, antiinflammatory, anti-microbial, and/or cel...
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WO/2017/027834A1 |
Provided herein are examples of metal chelating ligands that have high affinity for manganese. The resultant metal complexes can be used as MRI contrast agents, and can be functionalized with moieties that bind to or cause relaxivity cha...
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WO/2017/015722A1 |
The present disclosure relates to complexes for intracellular imaging and also to methods and kits for intracellular imaging or cell labelling. Certain embodiments of the present disclosure provide a complex comprising a transition metal...
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WO/2017/005822A1 |
The present invention relates to a X-ray fluorescence molecular probe of formula I or a salt thereof, wherein X, Het 1, R1, Y1, Y2, L and R2 are as defined in the claims. The invention also relates to the use of the probes of the inventi...
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WO/2016/203887A1 |
This novel compound is characterized by being represented by general formula (I) or (II). [In the formula, R1 and R2 each independently represent a hydrocarbon group having 1 to 12 carbon atoms, and a hydrogen atom in the hydrocarbon gro...
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WO/2016/205113A1 |
A number of new classes of polymers with the potential for electrical conduction are introduced sharing a common theme, having metal atoms in direct contact with each other, bound in one and two-dimensional structures guided by steric, d...
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WO/2016/189109A1 |
The present invention relates to a polyoxomolybdate-bisphosphonate complex containing a bisphosphonate ligand, wherein it further contains a heterometallic ion different from molybdenum, for use in treating cancer. It further relates to ...
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WO/2016/191424A2 |
The present invention includes novel compounds and compositions including heteroaromatic Silicon-Fluoride- Acceptors, which are useful for PET scanning. The present invention further includes a novel method of 18F imaging for PET scannin...
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WO/2016/181918A1 |
The present invention relates to a chemical vapor deposition starting material represented below that comprises a heterogeneous polynuclear complex in which cyclopentadienyl and a carbonyl are coordinated to a first transition metal and ...
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WO/2016/181917A1 |
The present invention relates to a chemical vapor deposition starting material represented below that comprises a heterogeneous polynuclear complex in which at least a diimine and carbonyl are coordinated, as ligands, to a first transiti...
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WO/2016/145156A1 |
This disclosure relates to compositions comprising substituted iminodiacetic acid ligands and metal tricarbonyl complexes containing the ligands and derivatives thereof. In certain embodiments, the metal tricarbonyl complexes are used as...
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WO/2016/136433A1 |
Provided are: a method for selectively reducing CO2 to carbon monoxide or formic acid using electrical energy; a catalyst used therefor; and an electrochemical reduction system. A method for manufacturing carbon monoxide or formic acid f...
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WO/2016/120365A1 |
Chromatography columns for the purification of eluates from 68Ge/68Ga generators comprising silica as stationary phase and purification processes that use said columns are described.
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WO/2016/077859A1 |
The present disclosure relates to methods and products for labelling, binding and/or detection of lipids. Certain embodiments provide a method of labelling a lipid. The method comprises exposing the lipid to a complex comprising a transi...
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WO/2016/037181A1 |
The present invention relates to metal complexes and methods of synthesizing the metal complexes. The invention is further directed to pharmaceutical and/or dietary supplement composition comprising compounds synthesized as described her...
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WO/2016/021402A1 |
The purpose of the invention is to provide a highly applicable novel organic-inorganic layered perovskite compound and a method for producing the same. A silsesquioxane cation represented by formula (I) can serve as an organic layer comp...
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WO/2015/194981A1 |
The disclosed invention relates to a new metalloligand of the formula [Mn(L)2(H2O)4]X2 and a method for its preparation and a metal-organic framework (MOF) constructed using the new metalloligand and a method for its preparation.
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WO/2015/166935A1 |
Provided are: a polymer comprising any of structural units represented by general formulae (1) to (3) in the polymer chain thereof, wherein at least a part of the structural unit has been stacked; a complex polymer wherein the aforesaid ...
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WO/2015/140337A1 |
The present invention relates to hybrid fumarate-CO-releasing molecules capable of increasing heme oxygenase-1 (HO-1) activity and HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic appl...
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WO/2015/103946A1 |
Disclosed is a higher fatty acid derivative marked with Technetium-99m, being a long chain fatty acid metabolism drug. The long chain fatty acid metabolism drug introduces sulfonyl and thiophen ring to long chain fatty acid to eventually...
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WO/2015/097325A1 |
Catalytic nanocages, uses and synthesis method. The invention relates to a novel family of metalorganic complexes, the supramolecular structure of which forms a cage, the size of said cage being modulable according to the composition of ...
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WO/2015/078880A1 |
The invention relates to a compound of the formula (I) T-Pep-BG (I) where, in formula (I), T is a solid support; Pep is a polypeptide bonded covalently to T, where the polypeptide has an amino acid sequence having 3 to 200 amino acids an...
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WO/2015/065823A1 |
Metal complexes containing one or more amidoimine ligands, methods of making such metal complexes, and methods of using such metal complexes to prepare metal-containing films are provided.
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