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WO/2003/099810A2 |
The present invention provides novel radiopharmaceuticals useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation ...
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WO/2003/093412A2 |
The invention provides novel amino acid compounds of use in detecting and evaluating brain and body tumors. These compounds combine the advantageous properties of &agr -aminoisobutyric acid (AIB) analogs namely, their rapid uptake and pr...
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WO/2003/093284A1 |
According to the invention, a novel type of contrast agent having a superparamagnetic behaviour at ambient temperature is synthesised for use as a contrast agent in magnetic image resonance. The invention relates to the use of a polymeta...
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WO/2003/087209A1 |
The invention relates to a silicone composition =SiH/=SiOH which can be polymerized/cross-linked by dehydrogenization with condensation in the presence of a catalyst which is suitably selected in order to complete one of the specificatio...
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WO/2003/084575A1 |
The disclosure provides pendant fatty acid compounds for use in diagnostic imaging, (particularly the cardiovascular system), as well as kits comprised of the same. The compounds comprise a metal chelating agent bound to a radionuclide c...
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WO/2003/077727A2 |
One aspect of the invention relates to novel complexes of technetium (Tc) with various heteroaromatic ligands, e.g., pyridyl and imidazolyl ligands, and their use in radiopharmaceuticals for a variety of clinical diagnostic and therapeut...
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WO/2003/079737A2 |
An organic electroluminescent device is described which comprises a compound having a skeleton of the formula (I): which skeleton can comprise one or more additional aromatic rings, wherein each of Z and Z', which may be the same or diff...
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WO/2003/074539A1 |
The invention provides bleach catalysts and bleaching compositions which exhibit a satisfactory bleaching effect even at low temperature, are reduced in the decoloring of dye and the damage to fiber, and are excellent in the effect of in...
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WO/2003/066067A2 |
Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g. rheumatoid arthritis, and of diseases with a strong inflammatory component, suc...
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WO/2003/062253A1 |
This invention relates to metal complexes which are useful as catalyst components in olefin metathesis reactions, atom or group transfer radical polymerisation or addition reactions and vinylation reactions. It also relates, preferably w...
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WO/2003/059510A2 |
Disclosed are manganese(IV) complex salts of formula [LMn(µ−O)3MnL)]n[XM12O40]m, (I), wherein L is 1,4,7−trimethyl−1,4−7−triazacyclononane, X is P or Si, M is Mo or W, n is 2 or 3, and m is 1 or 2, with the provisos that (i) i...
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WO/2003/053986A1 |
The use of metal complexes of compounds of formula I [..] Wherein the general symbols are as defined in claim 1, as oxidation catalysts.
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WO/2003/049850A2 |
The invention concerns a method which consists in producing powders with low hygroscopicity by vacuum drying of an aqueous solution, then by grinding, thereby obtaining a compound consisting of crystalline grains, whereof the moisture co...
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WO/2003/044031A1 |
The invention relates to a technetium or rhenium complex of formula (I): [M(R1CS3)2L] (I)in which M is Tc or Re, R1 represents an alkyl, cycloalkyl, aralkyl or aryl group which is unsubstituted or substituted by one or more substituents ...
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WO/2003/042135A2 |
Chiral ligands and metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The metal complexes according to the present invention are useful as catalysts in asymmetric reactions, such as, hydrigenation,...
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WO/2003/033617A1 |
Phosphorescent organometallic complexes comprising phenylquinolinato ligands are provided. High efficiency organic light emitting devices comprising these compounds are also described.
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WO/2003/008390A1 |
Compounds of general formula (I):in which: R¿1? is hydrogen, C¿1?-C¿2O? alkyl, C¿3?-C¿10? cycloalkyl, C¿4?-C¿2O? cycloalkylalkyl, aryl, arylalkyl, or two R1, taken together, form a straight or cyclic C¿2?-C¿10? alkylene group or...
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WO/2003/006070A2 |
The present invention relates to improved chelator conjugates of formula (II) with biological targeting molecules, suitable for forming metal complexes with radiometals. The radiometal complexes, especially with the radiometal?99m¿Tc, a...
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WO/2003/004014A1 |
The invention relates to complexes of general formula D¿2?-M-T, wherein D represents a $g(b)-diketone, M represents a metal atom and T represents a substance comprising at least one group containing N, O or S. The invention also relates...
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WO/2002/102707A2 |
Methods are provided for carrying out nucleophilic addition reactions using oxo, sulfido or amido complexes of transition metals as reaction catalysts. Exemplary catalysts are oxo complexes of Group 7 transition metals, with rhenium (V) ...
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WO/2002/095861A1 |
The present invention relates to a non-aqueous electrolyte addditive for improving safety and a lithium secondary battery comprising the same, and more particularly to a non-aqueous electrolyte additive taht can improve cycle life and sa...
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WO/2002/095860A1 |
The present invention relates to a non-aqueous electrolyte additive for improving safety and a lithium secondary battery comprising the same, and more particularly to a non-aqueous electrolyte additive that can improve cycle life and saf...
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WO/2002/088289A2 |
Use of metal complex compounds of formula (1): [L¿n?Me¿m?X¿p?]?z¿Y¿q? wherein Me is manganese, titanium, iron, cobalt, nickel or copper, X is a coordinating or bridging radical, n and m are each independently of the other an integer...
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WO/2002/085903A2 |
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compound...
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WO/2002/083774A2 |
Hybrid crystalline organic-inorganic quantum confined systems are disclosed, which contain alternating layers of a bifunctional organic ligand and a II-VI semiconducting chalcogenide, wherein the semiconducting chalcogenide layers contai...
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WO2001019823A9 |
The present invention relates to compounds which are effective as catalysts for dismutating superoxide and, more particularly, the manganese or iron complexes of substituted, unsaturated heterocyclic pentaazacyclopentadecane ligands whic...
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WO/2002/074736A1 |
The present invention relates to a novel diaminedithiol derivative or a pharmaceutically acceptable salt thereof; radiorhenium or radiotechneticum complex thereof; a composition for treating liver cancer comprising the radiorhenium compl...
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WO/2002/072519A2 |
A process for carrying out a chemical reaction which is catalysed by one or more metal or hydrogen fluoroalkylsulfonylated compound which process comprises carrying out said reaction in the presence of an ionic liquid or in solvent-free ...
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WO/2002/072260A2 |
A metal bis-triflimde compound having the formula: [M¿x?]?n+¿[(N(SO¿2?CF¿3?)¿2?)¿(nx-yz)?]?(nx-yz)-¿ [L¿y?]?z-¿ where M is a metal selected from the metals in groups 5 to 10, 12 and 14 to 16 and Cu, Au, Ca, Sr, Ba, Ra, Y, La, Ac...
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WO/2002/067761A2 |
Detectably labeled macrophage scavenger receptor antagonists useful for the diagnosis and monitoring of various cardiovascular diseases including but not limited to atherosclerosis, vulnerable plaque, coronary artery disease, renal disea...
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WO/2002/066159A1 |
A tethered ligand comprising the reaction product of an organofunctional silica and a ligand containing a functional group capable of reaction with said organofunctional silica, wherein the organofunctional silica is prepared from an alk...
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WO/2002/062398A2 |
The invention provides a complex comprising a) a compound formula (I): wherein R¿1?, X and n have any of the values described in the specification, or a pharmaceutically acceptable salt thereof; and b) a radionuclide. The complexes are ...
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WO/2002/059134A1 |
Transition metal complexes with chino[7,8-h]chinolines and cyclopentadieno[1,2-h: 4,3-h']dichinolines as proton sponge ligands and method for the production thereof. Said complexes are suitable as catalysts e.g. palladium complexes for a...
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WO2000075144A9 |
This invention provides a novel class of substituted macrocyclic metallic complexes. The complexes are useful as peroxynitrite decomposition catalysts. Pharmaceutical compositions, and methods of making and using the compounds, or a phar...
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WO/2002/053570A1 |
The present invention refers to the novel paramagnetic metal-phthalocyanine complexes and pharmaceutically acceptable salts thereof which are useful as contrast agents for MRI (Magnetic Resonance Imaging), diagnostic X-ray imaging and co...
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WO/2002/050088A1 |
A method to synthesize a Group 15 containing metal polymerization catalyst is disclosed. The method includes an efficient high temperature synthesis of Group 15 containing ligands, especially arylamine ligands, for use in preparing polym...
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WO/2002/044175A2 |
The present invention provides a compound for chelating a metal or a metal complex, characterized in that it consists of a bis-dithiocarbamate structure (F) having the formula below: (formule chimique ô insérer ici)in which n and m are...
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WO/2002/044187A2 |
This invention provides antioxidant cyclic salen-metal compounds, compositions of such antioxidant cyclic salen-metal compounds having superoxide activity, catalase activity and/or peroxidase activity and methods of using such antioxidan...
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WO/2002/031896A2 |
The present invention is generally directed to a polymeric metal complex comprising a polymeric material having a plurality of a first-type functional groups, wherein at least a portion of the functional groups are coordinated to at leas...
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WO/2002/026748A2 |
The first aspect of the present invention relates to transition metal complexes having the formula (I) or (II) wherein M is a radioactive metal having a valence of +2, +3, +4, or +5; m?+¿ designates the charge of the metal complex, each...
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WO/2002/002571A1 |
A process for the preparation of manganese complexes of salen compounds which comprises carrying out the reaction of a salen compound with a manganese compound in DMF is described. In a preferred embodiment, the salen compound itself is ...
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WO/2002/000603A1 |
The use of pamoic acid or of one of its derivatives is described with general formula (I), in which groups R1 and R5 are as indicated in the description, or of one of their pharmaceutically acceptable salts, for the preparation of a medi...
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WO/2001/098294A2 |
The present invention describes novel kits and compositions comprising compounds of the formula (I):(Q)¿d?-L¿n?-C¿h?, useful for the diagnosis and treatment of cancer in combination therapy in a patient. The present invention provides...
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WO/2001/089586A2 |
The invention relates to novel aminocarboxylate ligands that are suitable for complexing with a radionuclide, and are useful as therapeutic agents and as imaging agents for diagnostic purposes. In accordance with the present invention, a...
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WO/2001/090114A1 |
The invention concerns radiopharmaceutical products suitable for the selective labeling of lymphomas containing a metal complex with the formula: [m(R1CS2) (R1CS3)], in which M is chosen from among ?99m¿Tc, ?186¿Re and ?188¿Re, and R?...
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WO/2001/085717A1 |
Compounds are provided that may be used as ligands in transition metal complexes, in turn useful as bleach catalysts. Also provided are complexes, bleaching compositions and methods using the compounds. The compounds are of the general f...
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WO/2001/083436A2 |
The present invention relates to compounds of formula (I) (where the variables R¿A?, R¿B?, R¿C? and n are as defined in the claims) and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic tre...
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WO/2001/080905A2 |
The present invention provides novel sigma-2 ligands (labeled and unlabeled) and the use of the compounds in medical therapy or diagnosis (I).
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WO/2001/077122A1 |
This invention relates to novel highly functionalized phosphine ligands as ancillary ligands in radiopharmaceuticals. Also, this invention provides radiopharmaceuticals comprised of highly functionalized phosphine ligated ?99m¿Tc labele...
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WO/2001/077102A1 |
This invention relates to new macrocyclic chelants and metal chelates thereof, methods of preparing the chelants and metal chelates, and pharmaceutical compositions comprising the macrocyclic chelants and metal chelates. This invention r...
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