| Document |
Document Title |
|
WO/2018/233092A1 |
A method for preparing Rubusoside, comprising the following steps: grinding raw materials, performing flash extraction, double centrifugation, macroporous resin purification, desorption, enzymolysis, organic membrane grading decolorizati...
|
|
WO/2018/229493A2 |
The present invention generally relates to a process for the preparation of certain anticancer compounds as specific phosphate diastereoisomers.
|
|
WO/2018/229495A1 |
The present invention generally relates to a novel process for the preparation of 3'-deoxyadenosine derivatives,and particularly NUC-7738 (3'-deoxyadenosine-5'-O-[phenyl(benzyloxy-L-alaninyl)] phosphate) an anticancer ProTide of deoxyade...
|
|
WO/2018/215391A1 |
The invention comprises a process for the preparation of therapeutically valuable GalNAc cluster oligonucleotide conjugates. The process comprises the coupling of an alkali metal salt, earth alkali metal salt or a tetraalkylammonium salt...
|
|
WO/2018/215049A1 |
The invention comprises a process for the preparation of therapeutically valuable GalNAc cluster oligonucleotide conjugates. The process comprises the coupling of an alkali metal salt, earth alkali metal salt or a tetraalkylammonium salt...
|
|
WO/2018/213290A1 |
Methods of preparing highly purified steviol glycosides, particularly rebaudiosides M, D, E and I are described. The methods include utilizing enzyme preparations and recombinant microorganisms for converting various staring compositions...
|
|
WO/2018/212236A1 |
Provided is a novel oligonucleotide production method using a nucleoside or oligonucleotide that can be isolated easily and has high storage stability. An oligonucleotide production method including a coupling step of reacting a 5'-hydro...
|
|
WO/2018/209255A1 |
Aspects of the invention relate to novel synthetic compounds having binding affinity with galectin proteins.
|
|
WO/2018/207111A1 |
The present invention relates to an industrially feasible and economically viable process for preparation of SGLT2 inhibitors of formula (X) in significantly high yield and purity.
|
|
WO/2018/194330A1 |
The present invention relates to an SMB-based fucose separation method and an apparatus therefor and, more particularly, to a method and an apparatus for continuously separating fucose from a microalgae-derived monosaccharide mixture or ...
|
|
WO/2018/192502A1 |
Provided in the present invention are an antiviral precursor drug nucleoside cyclophosphate compound based on liver-specific delivery (LSD) technology and the use thereof, and in particular, provided in the present invention are a compou...
|
|
WO/2018/195179A1 |
Compositions comprising at least one steviol glycoside are provided for reducing increased blood sugar level (hyperglycemia) in Diabetes mellitus Type 1 and Type 2 patients.
|
|
WO/2018/191598A1 |
The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and ...
|
|
WO/2018/189546A1 |
The present invention relates to chemical linkers and protecting groups, compounds and compositions containing the chemical linkers or protecting groups, and intermediates and processes that can be used to prepare them. The chemical link...
|
|
WO/2018/185182A1 |
The present invention relates to a process for the selective isolation of highly purified, crystalline D-mannose from complex sugar mixtures, in particular from mixed wood sugars, more particularly from spent sulfite liquor (SSL).The pro...
|
|
WO/2018/177825A1 |
The present invention relates to the field of stereodefined phosphorothioate oligonucleotides and to stereodefining nucleoside monomers comprising an amine containing chiral auxiliary group, and methods of orthogonally protecting the nit...
|
|
WO/2018/177881A1 |
The present invention relates to the field of oligonucleotide synthesis using a solid support and in particular to the finding the when using a 3' oxy-LNA nucleoside attached to the solid support of the UnyLinker types, cleavage and depr...
|
|
WO/2018/175800A1 |
The present invention provides methods, devices, and kits to improve procedures for reducing carbohydrates, such as glycans released from glycoconjugates, or for labeling carbohydrates by reductive amination.
|
|
WO/2018/172129A1 |
The invention relates to sialic acid derivatives of formula (I) which contain a C-C triple bond, methods for the preparation thereof, conjugates produced therefrom and drugs containing same, wherein the symbols have the meanings defined ...
|
|
WO/2018/166475A1 |
The present invention relates to a stevioside M crystal form, a preparation method therefor and a use thereof, and specifically, relates to a naturally extracted high-intensity sweetener, i.e., a stevioside M crystal form A, the preparat...
|
|
WO/2018/166159A1 |
Disclosed are a Pezicula sp. SC1337 strain and a method for preparing trisaccharide ester derivatives using same. The preservation number of Pezicula sp. SC1337 is GDMCC No: 60144. Pezicula sp. SC1337 can be obtained by means of separati...
|
|
WO/2018/167293A1 |
Disclosed is a method of inhibiting isomerization of a reducing saccharide in an aqueous solution containing said reducing saccharide upon thermal treatment of said aqueous saccharide solution by acidifying the aqueous saccharide solutio...
|
|
WO/2018/165330A1 |
Stevia varieties with a high content of RebM, are disclosed Further provided are methods for producing Stevia plants having a high RebM content by negatively regulating certain genes selecting the resulting plants, and breeding with such...
|
|
WO/2018/163194A1 |
The present invention relates to a process for the preparation of D-glucitol, 1,5- anhydro-1-C-[4-chloro-3-[[ 4-[[(3S)-tetrahydro-3-furanyl)oxy )phenyl] methyl]phenyl]-, (IS) formula-1.
|
|
WO/2018/164937A1 |
This specification relates to a process for crystallizing an oligosaccharide, particularly a human milk oligosaccharide, and, more particularly, 2'-fucosyllactose ("2'-FL"). This specification also relates to compositions (e.g., crystall...
|
|
WO/2018/157141A1 |
The present invention relates, in part, to methods for large-scale purification of mRNA. The method includes, at least, a step of centrifuging an mRNA suspension in a centrifuge comprising a porous substrate at a speed sufficient to remo...
|
|
WO/2018/152870A1 |
The present invention falls within the field of biomass energy utilization, and in particular relates to a method for preparing levoglucosenone by means of the catalytic pyrolysis of biomass. The present invention uses a biomass-based ph...
|
|
WO/2018/153310A1 |
Disclosed are iridoids, and a preparation method and the use thereof. The preparation method comprises the steps of: (1) reflux extracting a whole plant with ethanol and water, recovering the ethanol, standing for precipitation, and filt...
|
|
WO/2018/149359A1 |
The present invention provides a triazole antibacterial derivative and a pharmaceutical composition and a use thereof, and in particular relates to a compound represented by the following formula (I), and a racemate, a stereoisomer, a ta...
|
|
WO/2018/149327A1 |
Disclosed is a method for preparing a canagliflozin form. The method comprises the following steps: adding canagliflozin into an organic solvent and dissolving same, then distilling into a certain amount of an oil; then, adding an anti-s...
|
|
WO/2018/138508A1 |
The invention relates to methods of synthesizing polymers, biopolymers, and nucleic acids, to immobilised dNTP/NTPs and kits comprising said immobilised dNTP/NTPs for use in said methods of nucleic acid synthesis.
|
|
WO/2018/140734A1 |
Compounds for use in prevention and/or treatment of pain are disclosed. The compounds are derived by conjugation of N 6-(4-hydroxybenzyl)adenosine and analogous compounds with amino acids or peptides. In one embodiment of the invention, ...
|
|
WO/2018/133600A1 |
Disclosed is a method for preparing high-activity sugarcane anthocyanin. The method comprises: 1) airing and crushing bagasse obtained after juice extraction, and adding distilled water to the bagasse; mixing cellulase, hemicellulase and...
|
|
WO/2018/134343A1 |
The present invention is directed to a compound of formula (III), its preparation and to its use for the preparation of a compound of formula (IV). The present invention hence is directed to a process for the preparation of compound of f...
|
|
WO/2018/129647A1 |
A purified oligosaccharide compound having antithrombotic activity or a mixture of a homologous compound thereof and a pharmaceutically acceptable salt thereof, a preparation method for the mixture, a pharmaceutical composition containin...
|
|
WO/2018/131711A1 |
The present invention relates to a method for manufacturing a sugar-containing cellulose hydrolyzate, the method including: a step (1) for dissolving cellulose in an acidic aqueous solution; a step (2) for mixing a cellulose-hydrolysis s...
|
|
WO/2018/127236A1 |
Disclosed is a preparation method for (2S,3R,4S)-2,3,4,5-tetrahydroxy-valeraldehyde, which solves the problems in the prior art that reaction conditions are harsh, processes are complex, product yield is low, purity is not high, and indu...
|
|
WO/2018/121559A1 |
A mannuronic dicarboxylic acid oligosaccharide composition, which comprises mannuronic dicarboxylic acid of formula (III) or a pharmaceutically acceptable salt thereof, where n is an integer selected from 1-9, M is selected from 0, 1, or...
|
|
WO/2018/124139A1 |
Provided are: a compound that induces a new type of stereoselective reaction that exhibits stereoselectivity during carbohydrate chain synthesis and produces acetal compounds; a production method for an acetal compound (e.g. a compound h...
|
|
WO/2018/113710A1 |
Provided in the present invention is a method for preparing a β-nucleoside compound, comprising the steps of: 1) performing a silylation reaction of a nitrogenous base or an analogue thereof in the presence of TMSOTf to obtain the nitro...
|
|
WO/2018/115309A1 |
The present invention relates to methods for preparation of glyco-conjugated proteins and in particular to processes for preparation of sugar-nucleotides and modified sugar-nucleotides.
|
|
WO/2018/113592A1 |
The present invention relates to a solid form of a compound of formula (I), a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and the use of the solid form in the treatment of a disease involv...
|
|
WO/2018/113652A1 |
Provided in the present invention are a compound as shown in formula (I), a pharmaceutical composition comprising same, and a preparation method and use thereof as a NS5B polymerase inhibitor, a DNA polymerase inhibitor or a reverse tran...
|
|
WO/2018/112189A1 |
Methods of preparing novel steviol glycosides are described herein. The methods utilize biocatalysts for converting a starting steviol glycoside to a target steviol glycoside. Compositions and consumables comprising said novel steviol gl...
|
|
WO/2018/107377A1 |
A purification process of NADPH is used for purifying a crude NADPH product obtained by biocatalytic preparation. The present invention resolves the technical problems of existing ion exchange resin methods having low yields and low puri...
|
|
WO/2018/109348A1 |
The present invention relates to a novel method for preparing surfactant compositions made from alkyl-L-iduronamides, alkyl-L-rhamnosides and alkyl-D-glucuronamides, the compositions obtained by said method and the uses thereof.
|
|
WO/2018/105933A1 |
The present invention relates to a method for efficiently utilizing fructose raffinate obtained when separating a psicose conversion reactant with a high-purity chromatograph in a psicose production process. Specifically, the present inv...
|
|
WO/2018/105931A1 |
The present invention relates to a method for preparing psicose by efficiently utilizing a psicose crystallization mother liquor obtained from a crystallization step of psicose and, more particularly, to a method for preparing psicose by...
|
|
WO/2018/103361A1 |
A method for preparing high-purity lactulose by efficient removal of sodium meta-aluminate, pertaining to the technical field of oligosaccharide preparation. The method comprises preparing a high-purity lactulose syrup and a product ther...
|
|
WO/2018/105934A2 |
The present invention relates to a method for efficiently utilizing fructose raffinate obtained from the separation of psicose conversion reactants through high-purity chromatograph in a psicose production process. Specifically, the obje...
|
