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WO/2022/110017A1 |
A method for purifying sucralose-6-ethyl ester, comprising: a preparation step: obtaining an ethyl acetate saturated solution of crude sucralose-6-ethyl ester heated to a predetermined temperature; a gradient crystallization step: perfor...
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WO/2022/110560A1 |
A porous resin used to solid phase synthesis and a preparation method therefor, specifically being a porous resin having functional groups being an amino group or a hydroxyl group and a preparation method therefor. Using an olefin compou...
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WO/2022/109171A1 |
The present invention relates to compositions and methods for the purification of ribonucleic acids including a polyA tail. The compositions and methods include a polystyrene divinylbenzene particle, a linker, and a poly-deoxythymidine o...
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WO/2022/107013A1 |
The present invention relates to a process for the synthesis of Fondaparinux pentasaccharide and its intermediates. Specifically, the present invention relates to a novel catalytic process for the synthesis of Fondaparinux pentasaccharid...
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WO/2022/103842A1 |
The present disclosure describes novel reagents and processes for preparing oligonucleotides, which have two or more nucleotides. In one embodiment, the reagent is represented by Formula I' or B.
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WO/2022/099606A1 |
A method for purifying sucralose, comprising: removing a solvent from a sucralose reaction liquid to obtain a concentrated solution of a sucralose crude product; under stirring, adding ethyl acetate to the concentrated solution of the su...
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WO/2022/094913A1 |
Disclosed are a sialic acid Neu5Ac derivative, and a preparation method therefor and the use thereof. The structure of the derivative is as shown in (VII)I below, wherein R1 is selected from hydroxyl, methoxy, or substituted methoxy; R2 ...
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WO/2022/096613A1 |
The present invention relates to a method for concentrating aqueous solutions of human milk oligosaccharides, in which an aqueous solution comprising at least one human milk oligosaccharide is subjected to a reverse osmosis process by me...
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WO/2022/099040A1 |
The present disclosure provides methods of anchoring active molecules on the surface of a cell, methods of anchoring at least two active molecules on the surface of a cell, and methods of enhancing an immune response to a target cell in ...
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WO/2022/089589A1 |
A flavonoid glycoside-organoamine DPP-4 inhibitor double salt. The flavonoid glycoside has the structural formula as shown in formula (1), wherein R1-R9 are independently selected from a group consisting of -H, -OH, C1-C6 alkyl, alkoxy o...
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WO/2022/089593A1 |
The present application relates to the technical field of pharmaceutical chemistry, and in particular relates to a double salt compound of a flavone glycoside-organic amine anti-tumor agent, a preparation method therefor and the use ther...
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WO/2022/089600A1 |
The present application relates to a double salt compound of flavonoid glycoside and an organic amine antimicrobial agent. The flavonoid glycoside has a structural general formula represented by the following formula (1), wherein R1-R9 a...
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WO/2022/090450A1 |
The present invention relates to a process for the purification of an acidic human milk oligosaccharide (HMO) from a fermentation broth using ion exchange methods. This process allows for a reduction of the number and/or extent of desalt...
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WO/2022/089598A1 |
A flavonoid glycoside and organic amine neuroagonist double salt compound, a preparation method therefor, and an application thereof, a pharmaceutical composition containing a therapeutically effective amount of the double salt compound ...
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WO/2022/083106A1 |
The present invention relates to the field of pharmaceutical chemicals, and relates to a method for preparing a glucosamine sulfate composite salt. The method comprises: adding N-acetylglucosamine and a solvent into a reaction vessel, th...
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WO/2022/084574A1 |
A method is presented for preparing samples for measuring a lignin content in a mass of pretreated lignocellulosic biomass particles. The pretreatment process comprises subjecting the lignocellulosic biomass particles to a hemihydrolysis...
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WO/2022/078612A1 |
The present invention relates to a method for releasing glycostructures from glycoproteins or enveloped viruses comprising glycostructures on their envelopes. Further, the invention relates to a method for isolating glycostructures from ...
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WO/2022/078487A1 |
The present disclosure provides a zolinose compound represented by formula (I), a preparation method therefor and a use thereof, wherein definitions of substituents are provided in the description. The zolinose compound has application p...
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WO/2022/075836A1 |
Provided are methods and systems for the production of alkyl polyglucoside. The methods and systems provide for improved purification that results in reduced produce degradation.
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WO/2022/072323A1 |
This specification relates to a process for preparing a purified human milk oligosaccharide ("HMO") from an HMO-containing solution (e.g., a fermentation broth) by a process comprising mixed bed ion exchange, and a product of such a proc...
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WO/2022/072333A1 |
This specification relates to a process for preparing a purified human milk oligosaccharide ("HMO") from an HMO-containing solution (e.g., a fermentation broth) by a process comprising anion ion exchange, cation ion exchange, and mixed b...
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WO/2022/067621A1 |
A sucralose purification method, sequentially comprising: putting sucralose in ultrapure water, heating for dissolving and then filtering, and extracting with an extraction solvent to remove non-polar impurities; evaporating an extracted...
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WO/2022/065384A1 |
Provided is an oilproofing agent capable of imparting high-temperature oilproofing properties using a bio-based material by means of an amide compound in which a C7-40 long-chain hydrocarbon group and an amide group have been modified by...
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WO/2022/056840A1 |
The present application provides a post-treatment method of a sucrose-6-carboxylic ester chlorination reaction liquid. The method comprises: adding ammonia water or water into the sucrose-6-carboxylic ester chlorination reaction liquid t...
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WO/2022/058312A1 |
A method of producing 1,4-dihydronicotinamide riboside (NRH) is disclosed. The method comprises providing nicotinamide riboside chloride (NRCl) in a liquid solution; adding a metal dithionite into the liquid solution under a first temper...
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WO/2022/056913A1 |
Provided is a preparation method for sucrose-6-carboxylate. The method of the present application comprises: passing a mixed solution containing sucrose, a mixed solvent and an organotin compound through a gas-liquid exchange reactor, an...
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WO/2022/061168A1 |
E-selectin ligands which are useful for the synthesis of E-selectin ligand-bearing carriers,wherein said E-selectin ligand-bearing carriers are directly or indirectly linked to or associated with at least one therapeutic agent, diagnosti...
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WO/2022/052393A1 |
A method for separating and preparing paeonidin-3-O-(6-p-coumaroyl) glucoside and malvidin-3-O-(6-p-coumaroyl) glucoside. Two high-purity acylated paeonidin and malvidin anthocyanin monomers are purified and separated from grapes by mean...
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WO/2020/249584A9 |
Disclosed is a process for the purification of LNnT (lacto-N-neotetraose) from a fermentation broth, the process comprises subjecting a fermentation broth to a first step of membrane filtration, thereby providing a filtrated solution, su...
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WO/2022/056428A1 |
5'-O-(Acetoacetyl)-2',3'-di-O-acetyluridine is useful in the treatment or prevention of disorders characterized by cerebral metabolic energy failure or diminished mitochondrial energy reserve capacity.
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WO/2022/052394A1 |
Disclosed in the present invention is a method for preparing a delphinidin-3-O-(6-O-p-coumaroyl) glucoside by separation. By means of steps such as extraction, macroporous resin purification, extracting, preparative liquid chromatography...
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WO/2022/051988A1 |
The present application provides a method for preparing sucrose-6-ester, comprising: preparing a reaction solution of sucrose and an organotin compound; atomizing the reaction solution to form small droplets; fully mixing and contacting ...
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WO/2022/049307A1 |
The invention relates to a process for the preparation of a product allulose composition comprising the steps of (a) providing a liquid allulose composition comprising allulose dissolved in water; (b) optionally, heating the liquid allul...
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WO/2022/048680A1 |
Provided is a method for preparing adenosine. The method comprises subjecting adenylic acid to a hydrolysis reaction in a protic solvent under an acidic buffer system. Also provided is a method for purifying adenosine. The method compris...
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WO/2022/034429A1 |
The present invention relates to a synthesis process of β-6-sulfoquinovosyl-diacylglycerols. In particular, said process is for the synthesis of the compounds 1,2-O-distearoyl-3-O-(β- sulfoquinovosyl)-R/S-glycerol, 1,2-O-distearoyl-3-O...
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WO/2022/034078A1 |
The present invention is in the technical field of cell cultivation or fermentation for the production of oligosaccharides. The present application discloses a method to produce a purified mixture of different oligosaccharides produced b...
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WO/2022/034079A2 |
The present invention is in the technical field of cell cultivation or fermentation for the production of oligosaccharides. The present application discloses a process for purification of an oligosaccharide solution produced by microbial...
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WO/2022/035078A1 |
The present invention provides a method, which extracts polydeoxyribonucleotides (PDRNs) from marine algae and depolymerizes same into a size of 50 kDa or less with an excellent skin and tissue penetration rate to finally prepare low-mol...
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WO/2022/033589A1 |
The present invention relates to a new crystal form of β-nicotinamide mononucleotide represented by formula (I) and a preparation method therefor. The method of the present invention does not use toxic and harmful organic solvents such ...
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WO/2022/029704A1 |
The present invention relates to a process for the preparation of a compound of formula (I) and to novel intermediates of the synthesis, wherein X is hydrogen, bromine or iodine; R1 is a protecting group, R2 is hydrogen or a protecting g...
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WO/2022/022472A1 |
Use of a nicotinamide nucleoside triaryl formate compound and a composition thereof in increasing the level of coenzyme I (NAD) in a human body, improving a health condition or treating a related disease, and a compound of formula (II-1)...
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WO/2022/026431A1 |
A method using an increase of agitation energy per unit volume in the crystallization of amorphous solid or spray dried solid starting material is provided. This method improves the efficiency of crystallization process and corresponding...
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WO/2022/016755A1 |
The present invention relates to the technical field of chemistry and medicines. Disclosed are a trehalose derivative and carbohydrate antigen conjugate, and a preparation method therefor and an application thereof. According to the pres...
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WO/2022/017390A1 |
A method for preparing a vitamin B12 crude product, comprising: filtering pseudomonas denitrificans after acidification, hydrolysis, and flocculation sedimentation, and respectively collecting filter residues and a filtrate; leaching the...
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WO/2022/017844A1 |
The invention relates to new rhamnolipid esters, to a method of their production and also to the use of the rhamnolipid ester as cosmetic additives.
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WO/2022/011554A1 |
The invention relates to a compound represented by general formula (I), a stereoisomer thereof, a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable ester thereof, a pharmaceutically acceptable hydrate thereof or pha...
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WO/2022/013430A1 |
The present invention relates to new glycolipids derivatives of Formula (I) and their use in the treatment of diseases related with a deregulation of the expression and/or activity of SK3 ion channels. The present invention further relat...
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WO/2022/012630A1 |
Disclosed is a method for preparing a C-nucleoside compound represented by formula (III), or a salt thereof. The present method has a high reaction yield, is simple to operate, uses a single metal reagent, has stable reaction temperature...
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WO/2022/013393A1 |
A process for synthesizing phosphoramidites by immobilizing a phosphitylating agent on an activated resin to create a loaded resin and then bringing the loaded resin into contact with a suitable substrate. The phosphoramidites are synthe...
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WO/2022/013500A1 |
The present invention relates to a method for obtaining surfactant compositions from raw plant materials. These surfactant compositions contain a mixture of n-alkyl glycosiduronic acid(s) and/or n-alkenyl glycosiduronic acid(s) and n-alk...
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