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JP2514070B2 |
A novel glucopyranose derivative of general formula: [wherein R<1> represents a hydrogen atom, a hydroxy group or an alkoxy group of from 1 to 4 carbon atom(s), R<2> represents the group represented by A, B, D or E [A represents a genera...
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JPH08506322A |
Substances comprising a N-sulfated or N-acetylated or non-sulfated N-acetylated 4-deoxy-4-en-iduronoglucosamine in substantially purified form, including compositions containing same and their uses are disclosed for the regulation of cyt...
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JP2510925B2 |
PURPOSE: To provide the subject compds. which are useful for the treatment and prevention of thrombosis, arteriosclerosis, etc., and particularly for the prevention of tissue aging and also useful as a standard compd. for biological reag...
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JP2510454B2 |
PURPOSE: To provide an org. synthesizing method to constitute fractions of acid mucopolysaccharides or to synthesize oligosaccharides. CONSTITUTION: The oligosaccharide consists of chains a-b, a-c or chains of two component units of (A-U...
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JPH08157491A |
PURPOSE: To inexpensively obtain the subject compound useful for medicines such as antitumor agent, cosmetics such as humectant and skin beautifying agents and safe and highly active surfactant, etc., in good yield by reacting an hydrous...
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JP2507107B2 |
Sucralfate is prepared in good yields and in newly useful form first by reacting sucrose with chlorosulfonic acid in 2-picoline. The amonium salt is then formed and reacted with aluminum chlorohydrate in specific sequence and alcoholic s...
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JPH08119987A |
PURPOSE: To obtain a new GLA-60 analog, an endotoxic copponent of enteric bacteria, showing excellent inhibitory action on macrophage activity as a lipopolysaccharide antagonist, useful as an immunosuppressive agent, a therapeutic agent ...
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JPH0899989A |
PURPOSE: To obtain a new glycolipid derivative useful as a ligand for binding to a cell adhesion molecule selection for a therapeutic agent for chronic inflammations by reacting a trichloroacetimidate derivative of new specific saccharid...
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JPH0892303A |
PURPOSE: To obtain an acidic saccharide, derived from a red algal mucilaginous polysaccharide and expected to have antitumor activities due to excellent immunopotentiating activities and the capability of inducing a tumor necrosis factor...
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JPH0881377A |
PURPOSE: To obtain a non-irritant, painless and safe eye drop having allergy- remedying effect through checking histamine liberation, containing, as active ingredient, a magnesium fructose-diphosphate. CONSTITUTION: This eye drop contain...
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JPH0853486A |
PURPOSE: To obtain the subject specific new 3-phosphonoglucosamine compound having excellent macrophage-activating action and activation-inhibiting action, and useful as an immune-activating agent, an anti-tumor agent, an antiinflammator...
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JPH0841093A |
PURPOSE: To obtain the subject novel compound derivative that is a sulfated α-glycolipid compound, has the inhibitory action of selectin-mediated cellular adhesion and are useful in the treatment or prevention of inflammatory diseases a...
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JPH08500820A |
Compounds and methods of making them having formula (I) are described which bind to selectin receptors and thus modulate the course of inflammation, cancer and related diseases by modulating cell-cell adhesion events. In formula (I), R1 ...
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JPH08500012A |
An enzymatic process is disclosed for the preparation of galactosyl beta 1,3glycal disaccharides such as Gal beta 1,3Glucal, an intermediate useful in Lea preparation and an inhibitor of beta -galactosidase. The process utilizes beta -ga...
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JPH07108911B2 |
The oligosaccharides of the invention contain or consist of a tetrasaccharide chain sequence of formula: in which R1 denotes an inorganic anion, R2 is identical with R1 or denotes a hydrogen atom, N1 and N2 denote an amine functional group.
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JPH07103009B2 |
Novel esterified oligosaccharides including at least one esterified disaccharide unit consisting of a uronic acid residue and a hexosamine residue can be topically applied to mammalian skin to improve the appearance of hair and other ben...
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JPH07509457A |
An esterification or amidation process comprises reacting a hydroxylated compound or an organic amine with an oxyacid or its anion capable of accepting a lone pair of electrons. The reaction has the advantage that it is carried out under...
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JPH07508730A |
A biologically active oligosaccharide compound comprising at least two L hexose rings connected together by an ether oxygen atom. The ether oxygen atom is connected to a first of the rings at the first carbon atom to the right of the hex...
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JPH07242691A |
PURPOSE: To obtain the subject new compounds, having carboxymethylene group at the 1-position and useful as an immunopotentiator or an antitumor agent having activating actions on a macrophage or an antiinflammatory agent, an immunosuppr...
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JPH07508037A |
A fused ring system compound is disclosed that contains an epoxide group on one side of the fused rings and an enediyne macrocyclic ring on the other side of the fused rings. The compounds have DNA-cleaving, antimicrobial and tumor growt...
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JPH07233186A |
PURPOSE: To provide novel BBM-1675D antitumor antibiotic which is produced by selective chemical hydrolysis of the bioactive component BBM-1675A1 or BBM-1675A2, has antibacterial activity and antitumor activity and is useful as formulati...
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JPH07188274A |
PURPOSE: To provide a new galactose derivative represented by a specific formula, capable of being added to liposome to prevent the association of the liposome and capable of labeling the tissue of specific affinity to galactose. CONSTIT...
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JPH07188030A |
PURPOSE: To obtain pharmaceuticals suitable for the treatment of gastric ulcers and for the control of Helicobacter pylori infectious disease. CONSTITUTION: This pharmaceutical contains moenomycin or its derivative and is suitable for th...
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JPH07188098A |
PURPOSE: To obtain novel compounds useful in the prophylaxis and treatment of bacterial diseases. CONSTITUTION: Novel compounds are represented by formula ] or formula II (wherein R1, R2, R4 and R5 are each H or y roxy; R3 is H and the b...
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JPH07505117A |
Methods of providing an image of the gastrointestinal region of a patient and diagnosing the presence of any tumorous tissue in that region using contrast media comprising a combination of at least one polyphosphorylated aliphatic or pol...
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JPH0739347B2 |
Use of a sulphated mono- or disaccharide or a salt or complex thereof for the preparation of a medicament for the prophylaxis or treatment of inflammation of an animal or a human i) for topical application to the skin or to any non-gastr...
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JPH07503709A |
A method of inhibiting tissue damage in warm blooded animals related to reperfusion of tissues after extended periods of ischemia is presented. The method comprises treatment prior to a planned ischemic event or up to six hours after an ...
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JPH0733393B2 |
Antibiotics BBM-1675C (Ia) and BBM-1675D (Ib) are new and are characterised by their physicochemical properties. - (Ia) and (Ib) are both hydrolysis prods. of BBM-1675A1 and BBM-1675A2 (esperamicin A1 and A2; see GB2141425), with (Ia) be...
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JPH0776595A |
PURPOSE: To provide novel compounds of salmycins showing high antibacterial activity against Gram-negative bacteria and useful as pharmaceuticals in treating infectious diseases. CONSTITUTION: The novel compounds (salts) are represented ...
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JPH0717509B2 |
The use compounds of the formula in which R is hydrogen or a radical -SO3M; M is a cation; R' and R'' are hydrogen or an alpha -glycosidically linked sulphated mono- or disaccharide residue; and where on average at least one -SO3M group ...
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JPH0753386A |
PURPOSE: To provide a high-caloric infusion pharmaceutical enabling blood ATP levels to be raised without involving the rise of blood sugar levels, thus useful for diabetics, etc. CONSTITUTION: The objective high-caloric infusion pharmac...
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JPH07500248A |
This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. ...
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JPH06102655B2 |
A 2,2-difluoro-2-desoxycarbohydrate is used to prepare antiviral nucleosides.
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JPH06102673B2 |
Sulphated O-Polysaccharide-trehaloses which can be used as medicaments, especially for the treatment of arteriosclerotic disorders.
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JPH0698011B2 |
A process for preparing glucose-1-phosphate from an alpha -glucan and orthophosphate using a phosphorylase immobilized onto an anion-exchange resin is disclosed. The anion-exchange resin used is a synthetic polymer resin into which an an...
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JPH0699460B2 |
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JPH0696585B2 |
A novel method for purifying a sugar phosphate or its salt, in which a sugar-containing mixture of a sugar phosphate or its salt and phosphoric acid or its salt is subjected to electrodialysis to remove the phosphoric acid or its salt fr...
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JPH0696586B2 |
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JPH06321948A |
PURPOSE: To provide a new compound having anti-microbial activity and useful for treatment of bacterial infections. CONSTITUTION: This is a compound of formula I (Z is O, S, sulfoxide, solfone; ring Z is a substituted ring of 4-6 members...
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JPH06279483A |
PURPOSE: To extremely simply and economically obtain the subject compound which is a raw material for hydroxy-ethyl-methyl-3(2H)furanone useful as a reagent, etc., for research for the metabolic pathway from a hydrolytic solution of a pr...
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JPH06271580A |
PURPOSE: To provide new compds. useful for the treatment of epilepsy, etc., as a prodrug of anticonvulsant agents, which are converted to an active medicine exhibiting anticonvulsant activity in the body of mammals. CONSTITUTION: The der...
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JPH06261780A |
PURPOSE: To obtain subject compound of high purity serving as a treating agent for diabetes, etc., by reacting fructose 6-phosphate with ATP and a phosphate donor in the presence of fructose-6-phosphate 2-kinase and an enzyme which conve...
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JPH0670030B2 |
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JPH06247994A |
PURPOSE: To obtain the subject new compound useful as immunopententiator, antitumor agent, etc., having excellent macrophage activating action and low toxicity by reacting a specific 4-phosphonoglucosamine with an aliphatic dicarboxylic ...
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JPH06506973A |
Highly sulfated oligosaccharides in the form of hexasaccharide and octasaccharide compounds which have antiproliferative activity with respect to smooth muscle cells are useful in treatment of conditions characterized by unwanted smooth ...
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JPH06206935A |
PURPOSE: To obtain a new sulfated sugar-containing polymer useful as an anticoagulant and an anticoagulative material for blood by using a polymer containing a (meth)acrylic acid derivative as a base skeleton and binding sulfated sugar t...
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JPH06206893A |
PURPOSE: To obtain the new disaccharide derivative for immunopotentiators, antitumor agents, antiviral agents, etc., consisting of a disaccharide derivative to which lipid is bound and having strong mitogen activity, adjuvant activity, a...
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JPH0643446B2 |
1. Claims for contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE Chitosan 6-sulfate of formula see diagramm : EP0148057,P4,F2 wherein n is an integer from 4 to 6000 and A represents a hydrogen atom or, in a number of up to 30% o...
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JPH06503804A |
A glucofuranose derivative substituted at the 3,5,6- or 3,6-positions with a radical that provides an anionic charge at physiological pH values is disclosed, as are pharmaceutical compositions, and methods of making and using the same. T...
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JPH0680657A |
PURPOSE: To efficiently obtain an axial-hydroxyglycal in high yield useful for intermediates or the like of an esperamicin an DNA cutting antibiotics or the like by reacting a substituted glycal compound having an equatorial ester group ...
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