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Matches 551 - 600 out of 9,972

Document Document Title
WO/2018/097239A1
The present invention addresses the problem of providing a clearing agent which is capable of, after administering a fusant of a streptavidin mutant with a molecular probe, preventing the localization of the fusant at a target site such ...  
WO/2018/089348A1
This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containi...  
WO/2018/083490A2
There is provided a molecule comprising a chain of seven or more contiguous units of 4,6-dideoxy-4-acylamido-α-pyranose, each pair of units joined by a C1-C2 or a C1-C3 link, the chain having a terminal end and a reducing end, wherein t...  
WO/2018/075874A1
Novel diterpene glycosides isolated from Stevia are provided herein. Compositions and consumables comprising the novel diterpene glycosides are also provided herein. Methods of enhancing the sweetness and/or flavor of consumables using t...  
WO/2018/068090A1
The present invention relates generally to the field of glycanics and its application to the generation of glycoconjugates for therapeutic use. The present invention also relates to process for the preparation of glycoconjugates.  
WO/2018/070546A1
[Problem] To provide a novel hydrogelator which can be produced by a simple method and contains a monourea compound having a sugar structure. [Solution] This hydrogelator comprises a compound represented by formula (1) below (in the form...  
WO/2018/067683A1
Novel diterpene glycosides containing ent-atisene cores are provided herein. Compositions and consumables comprising the novel diterpene glycosides are also provided herein. Methods of enhancing the sweetness and/or flavor of consumables...  
WO/2018/067805A1
Disclosed are solid state forms of Sotagliflozin, processes for preparation thereof, and pharmaceutical compositions thereof.  
WO/2018/068010A1
Compounds, compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin to an E-selectin ligand are disclosed. For example, highly potent multimeric ...  
WO/2018/067900A1
Provided herein are solid phase methods for the synthesis of conjugated oligomeric compounds and intermediates used in such methods. In particular, the solid phase methods provide for addition of a phosphoramidite functionalized conjugat...  
WO/2018/053202A1
The disclosure relates to the field of specialty chemicals. In particular, the disclosure provides novel 1,3-fatty-diol compounds of formulae (II) and (IV) and derivatives thereof, in partiuclar gycosides thereof, which are usefule.g.Jn ...  
WO/2018/050099A1
Provided is a panaxdiol-type ginsenoside derivative having a structure as shown in formula I or formula II. Also provided is the use thereof in the preparation of a drug for preventing and treating atherosclerosis. The panaxdiol-type gin...  
WO/2018/031585A1
The invention describes the extraction method to obtain the highest amount of resveratrol from wasted biomass produced by grapes processing. Resveratrol, which is found rich in the grapes, especially in grape skin and seed, is one of the...  
WO/2018/029272A1
A method for purifying rebaudioside M, which method comprises: (a) providing a solution comprising rebaudioside M at a concentration of at least about 10g/L and at a purity of at least about 10% by weight on a dry basis; and (b) crystall...  
WO/2018/030602A1
The present invention relates to: a novelly developed butane-tetraol-based amphipathic compound; a preparation method therefor; and a method for extracting, solubilizing, stabilizing, crystallizing, or analyzing membrane proteins by usin...  
WO/2018/029274A1
A method for purifying rebaudioside A, which method comprises: (a) providing a solution comprising rebaudioside A; (b) concentrating the said solution; and (c) crystallizing from the solution a high purity composition comprising rebaudio...  
WO/2018/026087A2
Compounds of chemical formula 1 or pharmaceutically acceptable salts thereof according to the present invention are sugar-added enclomiphene derivatives that improve bioavailability while maintaining antagonistic activity to estrogen rec...  
WO/2018/021527A1
The present invention addresses the problem of providing a method for supplying or maintaining type-17 collagen in a living body. The problem addressed by the present invention is solved by providing a composition having as an active ing...  
WO/2018/020046A1
The present invention provides a stable synthetic saccharide of Hib polyribosylribitol- phosphate (PRP) derivative and conjugate thereof. Said saccharide, said conjugate and pharmaceutical compositions thereof are hydrolysis-resistant, l...  
WO/2018/014866A1
Disclosed are a crystal form of a dapagliflozin intermediate and a preparation method therefor, and specifically disclosed are a crystal form of the dapagliflozin intermediate (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-eth ...  
WO/2018/014111A1
There is provided methods, compositions and treatment regimens for treating cancer, or for inhibiting metastasis/recurrence of cancer in a patient using 1) a primary cancer treatment such as chemotherapy, and 2) within 12 to 120 hours po...  
WO/2018/012669A1
The present invention relates to a mesitylene-cored amphiphile, a method of preparing the same and a method of extraction, solubilization, stabilization, crystallization or analysis of a membrane protein using the same. When a mesitylene...  
WO/2018/007495A1
The present invention relates to compounds of formula (I) and compositions comprising them for use in enhancing umami taste and/ or saltiness of a food product.  
WO/2018/007496A1
The present invention relates to compounds and compositions for use in enhancing flavor and/or saltiness of a food product. Particularly, the present invention relates to compounds of the general formula I) and compositions comprising them.  
WO/2018/005324A1
Disclosed herein are artificial Invaplexes comprising deacylated lipopolysaccharides and methods of making and using thereof.  
WO/2018/003652A1
A compound used in the conventional enzymatic reactions and mass spectrometry methods needs to be altered with respect to the structure thereof as a substrate compound, such as the length of an alkyl chain contained therein, depending on...  
WO/2017/218888A1
Compositions and uses for steviol glycoside compounds having four glucopyranose residues attached via the number 13 carbon (C13) of the steviol moiety and a second group of two or three glucopyranose residues attached via the number 19 c...  
WO/2017/207754A1
The invention describes novel conjugates of formula (I) of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein allowing a reversible release of the pharmaceutical agent depending on the glucose concentration.  
WO/2017/202351A1
The present invention relates to a new crystal form of a sodium-glucose co-transporter inhibitor medicine (Sotagliflozin) and a preparation method and use thereof. In addition, the present invention relates to a pharmaceutical compositio...  
WO/2017/205269A1
Compounds of Formula (I), compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin to an E-selectin ligand are disclosed. For example, haloalkyl ...  
WO/2017/199028A1
A method of preparing an active agent or a salt thereof from a prodrug first compound (1) comprising a propargyl group connected to an oxygen that is directly or indirectly connected to the active agent is provided, wherein the bond betw...  
WO/2017/196933A1
Methods of preparing freeze dried powders comprising rebaudioside M and rebaudioside D are provided herein. The freeze dried powders produced by the disclosed methods exhibit improved aqueous solubility over known forms and compositions ...  
WO/2017/185026A1
Reversibly blocked nucleoside analogues and methods of using such nucleoside analogues for sequencing of nucleic acids are provided.  
WO/2017/184884A1
Provided are methods and yeast cultures for producing polyol lipids and polyol lipid compositions.  
WO/2017/177326A1
The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to ta...  
WO/2017/178656A1
This invention generally relates to the field of phosphoramidite derivatives. In particular, the invention relates to N- Acetylgalactosamine (GalNAc) compounds, in particular phosphoramidite or phosphonoamidite molecules of formula (I) w...  
WO/2017/178497A1
The invention relates to a composition comprising one or more antimicrobial glycolipids and one or more formulation stabilizers. The invention also relates to methods of preparing the compositions and their application in water containin...  
WO/2017/179945A1
The present invention relates to an amphiphilic compound having a pentasaccharide hydrophilic group, a method for producing the same, and a method for extracting, solubilizing, stabilizing, crystallizing or analyzing a membrane protein a...  
WO/2017/174748A2
Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine- leucinol dipeptide linked to the lipid oligomer...  
WO/2017/176999A1
Disclosed are oligonucleotides that binds specifically to HIV neutralizing monoclonal antibody 2G12 with a K4 value lower than 20 nM, the oligonucleotide comprising a predicted structure, at 37°C, having exactly one stem-loop whereby th...  
WO/2017/173019A1
This invention relates to novel compositions comprising the reaction product of at least one acetoacetylated polyol and vanillin. The invention also relates to a method of making the novel compositions of the invention comprising the rea...  
WO/2017/167652A1
The invention relates to a compound characterised by a chemical dexpanthenol bound to a saccharide. The invention also relates to a corresponding compound for use in therapeutic and/or cosmetic methods.  
WO/2017/161986A1
A natural extract high-intensity sweetener steviol glycoside, specifically related to a novel steviol C-glycoside crystal, a preparation method for same, and applications thereof. The novel crystal has the advantages of high crystallinit...  
WO/2017/162825A1
The invention relates to a compound, characterized by a mono(2-hydroxyethyl) terephthalic acid (MHET) and a bis(2-hydroxyethyl) terephthalic acid which are chemically bound to a saccharide. The invention further relates to a correspondin...  
WO/2017/161987A1
The present invention relates to the naturally extracted high intensity sweetener stevioside, and specifically relates to a novel crystal form of steviolbioside, and a manufacturing method and application therefor. The novel crystal form...  
WO/2017/163808A1
The present invention addresses the problem of providing: a novel compound capable of activating a natural killer T cell, or a salt of the compound; a natural killer T cell activator comprising the compound or a salt thereof; and a pharm...  
WO/2017/161985A1
The present invention relates to a naturally-extracted high-sweetener stevioside, and in particular to a new crystal form of a rebaudioside B, and a preparation process therefor and a use thereof. The new crystal form is fully characteri...  
WO/2017/165619A1
The present invention relates to mannoside derivative compounds useful as inhibitors of FimH and methods for the treatment or prevention of urinary tract infection.  
WO/2017/157260A1
Provided are a phenylpropanoid and a preparation method and application thereof. The phenylpropanoid has a structure represented by formula (I), and a pharmaceutically acceptable salt thereof has a structure represented by formula (II) o...  
WO/2017/154938A1
[Problem] The purpose of the present invention is to provide a method for uniformly and efficiently producing a sugar having a sulfate group and/or phosphate group in the molecule or a compound containing the sugar. [Solution] The presen...  

Matches 551 - 600 out of 9,972