Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 51 - 100 out of 13,510

Document Document Title
WO/2020/236684A1
Stevia flavor compositions comprising a high level of reb audioside AM (Reb AM) are decribed. These compositions are flavors with modifying properties, or FMPs. Using an FMP, certain flavor notes in a consumable product may be enhanced, ...  
WO/2020/233680A1
An siRNA which inhibits kininogen (KNG) gene expression, a pharmaceutical composition containing the siRNA, and an siRNA conjugate. Each nucleotide in the siRNA is independently a modified or unmodified nucleotide. The siRNA contains a s...  
WO/2020/232534A1
Low permeability across the outer membrane is a major reason why most antibiotics are ineffective against Gram-negative bacteria. Agents that permeabilize the outer membrane are typically toxic at their effective concentrations. Here, we...  
WO/2020/231333A1
Provided herein are compounds, extracted from Wrightia antidysenterica, that are potent inhibitors of tyrosinase and melanogenesis, which can be used as skin whitening agents. Provided also are compositions comprising the compounds and m...  
WO/2020/105054A9
Modified aminoglycoside compounds represented by Formula I as defined and described in the specification are provided. The modified aminoglycosides feature a diamine-containing functional moiety at one or more of positions 3', 4' and 6'....  
WO/2020/218382A1
It has been expected to develop a novel GLP-1 secretagogue which promotes the secretion of GLP-1. The present invention provides a GLP-1 secretagogue characterized by comprising 0.4-4,440 ppm of a steviol glycoside having a structure to ...  
WO/2020/219417A1
Compounds, compositions, and methods for treating and/or preventing at least one disease, disorder, and/or condition associated with E-selectin, galectin-3, and/or CXCR4 chemokine receptor activity are disclosed herein. For example, mult...  
WO/2020/219419A1
Compounds, compositions, and methods for modulating in vitro and in vivo processes mediated by se lectin binding are described herein. For example, multimeric selectin modulators and their use are described, wherein the multimeric select...  
WO/2020/213891A1
The present application relates to a sweetener composition comprising a fructose-transferred steviol glycoside, and a method for improving sweetness of a steviol glycoside comprising a step of converting the steviol glycoside to a fructo...  
WO/2020/183442A3
The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicr...  
WO/2020/214901A1
Compositions and methods for protecting an organism from a pathogen are disclosed.  
WO/2020/210907A1
The present disclosure relates to processes for recovering valuable products from Fabaceae family plant fractions, in particular from Medicago sativa ssp. The processes disclosed herein include processes for obtaining macrofibers, microf...  
WO/2020/205978A1
Compositions comprising brazzein (or analogs thereof), including sweetener compositions, flavor modifying compositions, sweetened compositions, flavor modified compositions are disclosed. Also disclosed are methods of improving the tempo...  
WO/2020/198878A1
The present application provides compounds, compositions and methods to reduce, alleviate or treat various enteric diseases and disorders, such as inflammatory bowel disease. The compounds are xyloglucan-containing prodrugs, referred to ...  
WO/2020/150751A3
Disclosed are devices, kits, apparatus, and methods for rapid homogenous cell staining and imaging.  
WO/2020/194237A1
Methods of rapidly inhibiting efflux from a cell, sensitizing a drug-resistant cell to a drug and treating a subject with a drug-resistant pathology, by administering tetrahydrocannabinolic acid (THCa), cannabidiol (CBD) or a combination...  
WO/2020/189734A1
Provided is a compound or salt thereof represented by formula (I) below [In formula (I), R1 represents –COOH or –CY1Y2OH (where, Y1 and Y2 each represent a hydrogen atom or a detectable marker), A1 represents a sugar or an aglycone, ...  
WO/2020/183442A2
The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicr...  
WO/2020/177568A1
The present invention relates to an LL-D49194α1 analog, a preparation method therefor and an application thereof. Specifically, provided by the present invention is a deglycosylated and demethylated LL-D49194α1 analog. The obtained LL-...  
WO/2020/178053A1
Phenol derivatives of general formula (I) and (II), wherein meanings of the substituents are indicated in the description, their pharmaceutically acceptable salts, together with the processes for their preparation, their use as antimicro...  
WO/2020/172755A1
Disclosed are compounds of formula (I): Yp–X–L2–Z, (I) or a salt thereof, where p is 1 to 5; X is a monosaccharide; each Y is independently –L1–T, H, protecting group, optionally substituted hydrocarbon, or optionally substitut...  
WO/2020/175648A1
The present invention is a diblock-type oligomer, which has a pyranose block and an alkyl pyranose block and is represented by formula (I) in figure 1 (in formula (I), each R1 independently represents a methyl or an ethyl, m is 1.0 to 3....  
WO/2020/176470A1
Provided is a method of treating benign prostatic hyperplasia (BPH) in a patient. Also provided is a method of inhibiting non- adrenergic contraction of a smooth muscle. Additionally provided is a method of inhibiting proliferation of hu...  
WO/2020/176602A1
Mogrosides containing non-glucose glycosides are provided herein. Compositions, including consumables comprising the novel mogrosides described herein, are also provided.  
WO/2020/168312A1
Methods of preparing highly purified steviol glycosides. The methods include utilizing enzyme preparations and recombinant microorganisms for converting various starting compositions to target steviol glycosides. The highly purified stev...  
WO/2020/163693A1
Reformulations of gentamicin for treatment of infections are provided with the goal to reduce current side effects such as ototoxicity, while maintaining antimicrobial activity. The reformulation is a mixture of three of the C-components...  
WO/2020/157494A1
Described herein are compounds comprising a dimer of dehydrosalicortin or a derivative, homologue, stereoisomer, prodrug or pharmaceutical salt thereof. In particular embodiments, the dimer is a result of a Diels-Alder reaction. Also des...  
WO/2020/158995A1
The present invention provides a novel rhamnolipid compound, an optical isomer thereof, or a pharmaceutically acceptable salt thereof. A novel rhamnolipid compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof,...  
WO/2020/155519A1
Disclosed is a synthesis of a Helicobacter pylori O2 serotype O-antigen oligosaccharide compound, which belongs to the field of organic synthesis. The invention obtains, through chemical synthesis, Helicobacter pylori O2 serotype O-antig...  
WO/2020/139788A3
The invention relates to the targeted delivery of therapeutic molecules to organs, tissues, and cells of humans and other mammals. The invention is directed to a chemical construct for delivering such therapeutic molecules and to methods...  
WO/2020/155494A1
A preparation method of a sweetener composition comprises the following steps: acquiring minced leaves of Rubus suavissimus; using water as a solvent to perform extraction; removing phenolic hydroxyl group-containing components; performi...  
WO/2020/072931A3
The present disclosure provides inosine-5'-monophosphate dehydrogenase (IMPDH)-inhibiting nucleoside derivatives having anti-infective activities, and methods of their synthesis and use.  
WO/2020/148641A1
The present invention relates to a process for preparation of 2-Amino-5-hydroxypropiophenone, a key intermediate for the synthesis of camptothecin analogs including 7-Ethyl-10-hydroxycamptothecin (SN-38).  
WO/2020/135898A1
The present invention provides synthetic oligosaccharide fragments from the terminal pentasaccharide of the lipooligosaccharide of Bordetella pertussis, and a method for obtaining the synthetic oligosaccharides fragments and conjugates f...  
WO/2020/137706A1
[Problem] The purpose of the present invention is to provide a new method for producing a cycloastragenol analog from astragaloside IV. {Solution] A method for producing a cycloastragenol analog that includes a contact step that brings a...  
WO/2020/106357A3
Mithramycin (MTM) short side chain ketone (SK) derivatives and MTM short side chain diketone (SDK) derivatives are provided. The MTM SK and MTM SDK derivatives are useful for treatment of cancer or neuro-diseases associated with an aberr...  
WO/2020/125307A1
Disclosed is a method for constructing a Pseudomonas aeruginosa O11 serotype O antigen oligosaccharide using a D-glucose block, a L-fucosamine block and a D-fucosamine block, wherein the D-glucose block or the L-fucosamine block is conne...  
WO/2020/127194A1
Anticancer compounds of formula (I) and derivatives thereof are provided.  
WO/2020/123877A1
The present invention relates to novel steviol glycosides R6-1, R6-2A, R6-2B, R6-4A, R6-4B and R7-2 and the production of these novel steviol glycosides, such as through enzymatic bioconversion. The use of these novel steviol glycosides ...  
WO/2020/120474A1
The present invention provides certain tetrapyrrolic compounds having a structure of Formula (1), (2), or (3) wherein B is (I), (II) (III) or (IV), O-R1 is a substituent in the meta or para position of the phenyl ring, R1 is a glyco-subs...  
WO/2020/115190A1
The present invention relates to novel aminoglycoside compounds having antimicrobial properties and being suitable, for example, as therapeutic agents for use in the treatment of mammalian disease and in particular to novel therapeutic a...  
WO/2020/113926A1
The present invention relates to the field of modification and extraction of natural compounds. Disclosed is a method for realizing a high value for a stevioside mother liquor sugar. According to the present invention, lactase is used to...  
WO/2020/114418A1
The present invention relates to an anticoagulant compound having an anionic form represented by formula (A), a preparation method thereof, and a use of the same in preparing a drug for preventing and/or treating a disease related to coa...  
WO/2020/114287A1
The present invention relates to a ruthenium-nickel/activated carbon co-supported catalyst, a preparation method therefor and a use thereof in the preparation of sugar alcohols by means of sugar catalysis and hydrogenation. According to ...  
WO/2020/111280A1
The present invention provides a nucleic acid complex represented by formula 1. Formula 1: (In formula 1, X is a double-stranded nucleic acid that comprises a sense strand and an antisense strand and that includes a duplex region of at l...  
WO/2020/108149A1
Disclosed is a preparation method for cyclic purification of mother liquor sugar and extraction of renaudiside (RA) and stevioside (ST), comprising heating and stirring a mother liquor sugar comprising more than 70% of total glycosides w...  
WO/2020/113124A1
Provided herein are methods of treating an ocular disease associated with one or more nonsense mutation in a subject using one or more aminoglycosides and/or derivatives thereof. The pharmaceutical compositions and kits containing one or...  
WO/2020/112957A1
Methods of preparing highly purified steviol glycosides, particularly steviolmonoside, steviolmonoside A, steviolbioside, steviolbioside D, rubusoside, steviolbioside A, steviolbioside B, rebaudioside B, stevioside, rebaudioside G, stevi...  
WO/2020/104335A1
The present invention relates to a compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal...  
WO/2020/102910A1
Herein, we describe the development of non-β-lactam-based potentiator molecules that synergize with β-lactam antibiotics and β-lactam-β-lactamase inhibitor combinations against MDR/XDR P. aeruginosa phenotypes. The compound comprises...  

Matches 51 - 100 out of 13,510