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Matches 401 - 450 out of 13,501

Document Document Title
WO/2016/115048A8
Provided are organic solvent free methods for obtaining compositions comprising one or more rhamnolipids as well as compositions obtainable from said methods.  
WO/2017/063617A1
The present invention relates to a preparation method of the intermediates of structures la (for the synthesis of canagliflozin) and 1b (for the synthesis of dapagliflozin), where in structure la X is methyl and Ar represents 2-(5-(4-flu...  
WO/2017/062800A1
Disclosed are compounds for the selective labeling of cell-surface sugars in cancer cells. The compounds are activatable by triggers specific to cancer cells, and, when metabolized, label a cancer cell surface sugar with an azide chemica...  
WO/2017/058474A1
Prepare a branched alcohol-based sugar surfactant by: (a) providing an ether alcohol and a fully acetylated sugar where the ether alcohol has the structure of Structure (I); (b) coupling the ether alcohol with the acetylated sugar in the...  
WO/2017/059318A2
The present disclosure relates to scaphopetalone analogs, methods of making the analogs, and their medicinal uses.  
WO/2017/051875A1
Provided is a compound represented by formula (I) or a salt thereof (in formula (I): R1 and R2 each represent hydrogen, a C1-5 straight-chain or branched alkyl group, a C1-5 straight-chain or branched alkoxy group, or a C1-5 straight-cha...  
WO/2017/049386A1
This invention discloses the use of aminoglycoside antibiotics such as gentamicin Bl to suppress premature termination codons during translation and promote the full length read-through of transcripts such as p53 that incorporate nonsens...  
WO/2017/046172A1
The invention relates to carbohydrate ligands and moieties, respectively, mimicking glycoepitopes comprised by glycosphingolipids of the nervous system, particularly glycoepitopes comprised by glycosphingolipids of the cerebroside, the g...  
WO/2017/046535A1
The subject matter of the present invention is a compound characterized in that it has the general formula (I): in which P1, X, n, A, L and L1 are as defined in Claim 1. The present invention also relates to a process for preparing said ...  
WO/2017/043703A1
The present invention relates to a mannitol-based amphipathic compound, a method for preparing the same, a method of extraction, solubilization, stabilization or crystallization of a membrane protein using the same, and a method for anal...  
WO/2017/037719A1
Novel aminoglycosides, represented by Formulae la and lb, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are pharmaceutical compositions containing the s...  
WO/2017/037718A1
Novel pseudo-trisaccharide aminoglycosides, represented by Formula I, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are pharmaceutical compositions cont...  
WO/2017/039107A1
The present invention relates to a xylene-based amphipathic compound, a method for preparing same, and a method for extracting, solubilizing, stabilizing, or crystallizing membrane proteins by using said compound. By using the xylene-bas...  
WO/2017/037717A1
Novel pseudo-disaccharide and pseudo-trisaccharide aminoglycosides, represented by Formulae I or Ia, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are p...  
WO/2017/027968A1
Adjuvants which rescue antibiotics against multidrug-resistant (MDR) organisms are a promising combination strategy to overcome bacterial resistance. While the combination of β-lactam β-lactamase inhibitor antibiotic has been successfu...  
WO/2017/031189A1
The invention provides compositions and methods for the production of TDP-deoxysugars.  
WO/2017/021385A1
The invention comprises a new process for the preparation of GalNAc derivatives of the formula I wherein n is an integer between 0 and 10 and its salts, corresponding enantiomers and/ or optical isomers thereof. The GalNAc acid derivativ...  
WO/2017/017509A1
The present invention relates to novel oligomers of Neisseria meningitidis serogroup Y capsular polysaccharide repeating unit (Men-Y oligomers) and process for synthesizing novel Men- Y oligomers. In particular, the present invention rel...  
WO/2017/019599A1
A process for the extraction and concentration of saponins from agricultural feedstocks. An agricultural feedstock can undergo a first preparation step intended to increase surface area of the feedstock for increased efficiency in extrac...  
WO/2017/018528A1
Disclosed are: a compound represented by general formula (I), or a pharmaceutically acceptable salt of the compound, or a solvate of the compound or the pharmaceutically acceptable salt; a pharmaceutical composition containing the compou...  
WO/2017/012289A1
Disclosed are compounds which can act as a positive allosteric modulator for erythropoietin and erythropoietin receptor and have the activity in promoting erythropoiesis. Also disclosed are pharmaceutical compositions comprising said com...  
WO/2017/012572A1
Provided are crystalline form A of rebaudioside D, and a preparation method and application therefor. In X-ray powder diffraction analysis measured using Cu-Kα rays and with 2θ being expressed in degrees, crystalline form A of rebaudio...  
WO/2017/007346A1
The present invention relates to novel derivatives of polyphenol glycoside or polyalcohols of formula (1), wherein R1, R2, R3 is selected from the group consisting of H, OH, C(O)R4, C(0) OR4, 0 (Gly H3)n, wherein n = 0 1, 2, 3, and R4 is...  
WO/2016/100833A3
In one aspect, the present invention provides novel derivatives of trioxacarin analogs of the formula (I) wherein the variables are as defined herein. The application also provides compositions, methods of treatment, and methods of synth...  
WO/2016/202310A1
A sulphonated pentasaccharide compound having anti-Xa factor activity, and a preparation method and use for said compound. The compound is a derivative of a pentasaccharide compound having an anticoagulation effect, and has significant a...  
WO/2016/198170A1
The present invention relates to well-defined synthetic saccharides of general formula (I) that are related to the repeating unit of Streptococcus pneumoniae serotype 5 capsular polysaccharide and conjugates thereof. The conjugates and p...  
WO/2016/196927A1
Methods of using and pharmaceutical compositions comprising (2R,3S,4R,5R,6S)-5- amino-6-(((lR,2S,3S,4R,6S)-4,6-diamino-3-(((2R,3R,4R,5R)-3,5 -dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl) oxy)-2-hydroxycyclohexyl)oxy)-2- (h...  
WO/2016/189179A1
The invention relates to a compound of general formula (I), and to the use thereof in medicine, or for the production of a medicine for the treatment of different diseases, preferably a cancer such as melanoma, lung carcinoma or breast c...  
WO/2016/188381A1
The present invention relates to the technical field of medical compounds, and relates to an oxidized β-1,4-oligoglucuronic acid, and a preparation method therefor and uses thereof. In the present invention, by using abundant cellulose ...  
WO/2016/190383A1
A compound represented by structural formula (A) or (B); a method for producing the compound; a microorganism having an ability of producing the compound represented by the formula (A) or (B); and a compound-containing composition and an...  
WO/2016/181013A1
The invention relates to the use of oligosaccharides as stimulators of plant growth in already germinated plants and to a method for obtaining said oligosaccharides. The invention particularly relates to the use of oligosaccharides compo...  
WO/2016/180818A1
The present invention relates to glycosylating polyphenols via biocatalysis. More specifically the present invention discloses particular mutants of the thermostable sucrose phosphorylase derived from the microorganism Thermoanaerobacter...  
WO/2016/180729A1
Apparatus and methods for reducing biofouling in drink such as beer dispensing equipment are described.  
WO/2016/173425A1
This present invention relates to a glucopyranosyl derivative as sodium dependent glucose cotransporters (SGLTs) inhibitor, preparation processes thereof, and pharmaceutical uses thereof, pharmaceutical compositions containing the compou...  
WO/2016/169288A1
The present invention relates to the field of pharmaceutical chemistry. Disclosed are a new amorphous piceatannol 3'-O-glucoside, preparation method thereof, and pharmaceutical composition containing the same. The amorphous piceatannol 3...  
WO/2016/172615A1
The present invention provides N-acetyl-muramic acid (NAM) derivatives having Formula I, wherein Xa is selected from the group consisting of X1-X59, Ya is selected from the group consisting of H, monophosphate, uridine diphosphate and et...  
WO/2016/164921A1
In various embodiments, the invention provides a radiotracer comprising a positron emitting atom bound to a deoxy sugar moiety. The radiotracer is reversible bound to a caging moiety that prevents or retards tissue uptake of the radiotra...  
WO/2016/161951A1
A phillygenin glucuronic acid derivative represented by general formula (I). In general formula (I), R1=H, R2=CnH2n+1, and R3=CnH2n+1; or R1=CnH2n+1, R2=CnH2n+1, and R3=H; or R1-R2=-CH2-, and R3=CnH2n+1; n=1 to 30. The present invention ...  
WO/2016/164394A1
Compounds, compositions, and methods for treatment and/or prevention of at least one disease, disorder, or condition by inhibiting binding of an E-selectin to an E-selectin ligand are disclosed, For example, E-selectin antagonist therape...  
WO/2016/161377A1
This disclosure relates to the incorporation of amphiphilic guanidinylated aminoglycosides (e.g., neomycin) into liposomal assemblies, which contain entrapped therapeutics. The lysosome is responsible for enzymatically breaking down and ...  
WO/2016/156338A1
The present invention relates to synthetic saccharides of general fornnula (I): V*−[Ux+2−Ux+ 1−Ux]n−V−O−L−NH2 that are related to carbapenem-resistant Kliebsella pneumoniae capsular polysaccharide and conjugates thereof. Sa...  
WO/2016/159537A1
The present invention relates to a phytospingosine derivative generated by a condensation reaction of phytospingosine and maltose or lactose, which is an aldose-based disaccharide, and to a composition containing the same. The phytosping...  
WO/2016/159092A1
In the present invention, an organic acid salt of 4'-epidaunorubicin or a hydrate or a solvate thereof is used as a novel production intermediate, whereby it is possible to efficiently remove 13-dihydroepidaunorubicin and 4'-epifeudomyci...  
WO/2016/155888A1
The present invention relates to novel compounds of the formula I, methods for their preparation and their use for treatment of diseases. The invention discloses the synthesis of levodopa (L-DOPA) esters by coupling polyhydroxy compounds...  
WO/2016/145997A1
Disclosed are a pharmaceutically active sugar molecule and a synthesis method thereof. The sugar molecule has a structure as shown by formula (I) or (II) and can be used for synthesizing a sulfonated sugar molecule, so that it can be fur...  
WO/2016/145478A1
The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of kidney and/or liver disease.  
WO/2016/146941A1
The present invention relates to a new method for producing D-galacturonic derivatives and compositions having the formula (I) directly from pectins or pectin depolymerisation products, and to their use as surface active agents.  
WO/2016/040369A3
Glycosphingolipids (GSLs) compositions and methods for iNKT-independent induction of chemokines are disclosed.  
WO/2016/144175A1
The present invention relates generally to the production of steviol glycosides. Provided is a method for enzymatically providing a modified steviol glycoside, comprising incubating a steviol glycoside substrate in the presence of sucros...  
WO/2016/143939A1
The present invention relates to a production method for a complex of a steviol glycoside and a sparingly soluble material having improved solubility, and to a complex of a steviol glycoside and a sparingly soluble material having improv...  

Matches 401 - 450 out of 13,501