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Patent Searching and Data


Matches 451 - 500 out of 6,658

Document Document Title
WO/2009/039177A1
The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: formula (I) which exhibit antibacterial properties. The present invention further relates to pharmaceutical comp...  
WO/2008/157751A3
The present invention provides substituted imidazoheterocyclic compounds having the structure of Formula (I) Also provided are pharmaceutically acceptable salts, acid salts, hydrates, solvates and stereoisomers of the compounds of formul...  
WO/2009/022009A1
The invention relates to a pharmaceutical composition according to claim 1 comprising a pyrazole-O-glucoside derivative in combination with a DPP IV inhibitor which is suitable in the treatment or prevention of one or more conditions sel...  
WO/2009/023196A1
Provided are compounds of formula (III) useful for modulation of immune responses, compositions comprising the compounds, and methods of use of such compositions for treating diseases or disorders involving an immune response. In certain...  
WO/2009/023191A2
The present invention includes a process involving a one-pot reaction for preparing erythromycin 9-oxime salt comprising: (a) reacting erythromycin thiocyanate with an ammonium source to obtain erythromycin free base; (b) oximating the C...  
WO/2009/021163A2
Described herein are methods of improving the efficiency of gene transfer for a wide range of applications. Specifically provided are methods of increasing expression of an exogenous gene in a cell by contacting the cell with a vector co...  
WO/2009/019868A1
Disclosed is a novel 10a-azalide compound crosslinked at position-10a and position-12, which is represented by the formula shown below and is effective against an influenza bacterium or an erythromycin-resistant bacterium (e.g., an eryth...  
WO/2009/016142A1
The present invention relates to novel 2'-O-substituted 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A derivatives having antimalarial activity. More particularly, the invention relates to 2'-O-substituted-9-deoxo-9a-methyl-9a-aza-9a-hom...  
WO/2009/015541A1
The present invention discloses novel polyene diesters of formula 1 and their preparation. The diesters are used as prodrugs by introducing diester group to polyene antibiotics, which exhibit antifungal or antiviral activity through rele...  
WO/2008/110918A3
The invention relates to compounds of Formula (I) wherein R1, R2, and X are as defined herein. The invention also relates to pharmaceutical compositions and methods of treating bacterial infections using compounds of Formula (I).  
WO/2009/013351A2
This invention relates to solvated and non-solvated crystalline forms of 20,23- dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from)such crystalline form...  
WO/2009/009906A1
A method for producing one or more than one isoflavonoid compound in a plant is described. The method comprises providing a production plant comprising one or more than one nucleotide sequence encoding isoflavone glycosyltransferase oper...  
WO/2009/007988A1
The present invention relates to process for the preparation of 6-O-methylerythromycin A 9-oxime by treating 6-O-methylerythromycin A with hydroxyl amine hydrochloride in the presence of a base and a solvent.  
WO/2009/004322A2
The present invention provides a compound of formula (I') which is a nystatin derivative having an additional double bond present between C28 and C29 and which is further modified relative to nystatin at one or more of positions C5, C7, ...  
WO/2008/157751A2
The present invention provides substituted imidazoheterocyclic compounds having the structure of Formula (I) Also provided are pharmaceutically acceptable salts, acid salts, hydrates, solvates and stereoisomers of the compounds of formul...  
WO/2008/136037A3
The method, object of the present invention, concerns the peracylation of oleuropein and its products of hydrolysis: The method makes use of the excellent properties as Lewis acid catalysts of halides and tryphilates of lanthanides (III)...  
WO/2008/148223A1
The present invention provides a novel method for the transduction and/or transfection of plant cells. Cell-penetrating peptides (CPPs) have been successfully employed as nanocarriers to deliver proteins and oligonucleotides to single pl...  
WO/2008/143677A1
Stable solid, crystalline forms of elsamitrucin salts are provided that are useful in preparing anti-neoplastic parenteral formulations. Also provided are methods for treating neoplastic diseases in humans using parenteral formulations t...  
WO/2008/138243A1
Provided is a preparation method of icaritin, comprising treating the icariin with β-glucosidase in ethanol-water solution, then obtaining the icaritin by centrifugation and recrystallization. Also provided is a preparation method of ic...  
WO/2008/106226A3
The present invention provides triazole macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO/2008/139965A1
Disclosed is a vitamin B6 derivative having photostability and also having both of a proper water-solubility and a proper lipid-solubility. Specifically, the vitamin B6 derivative is a compound represented by the general formula (I) or a...  
WO/2008/014221A3
The present invention discloses compounds of formulae (I) and (II) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical composi...  
WO/2006/025983A3
This invention provides labeled-substrate conjugates for assaying enzymes, particularly neuraminidases. Also provided are assays that are useful for identifying compounds that inhibit sialyltransferases or neuraminidases and may be usefu...  
WO/2008/111020A3
The present invention provides macrolide derivatives, which can be used as antibacterial agents. Compounds disclosed herein can be used for treating or preventing conditions caused by or contributed to by gram positive, gram negative or ...  
WO/2008/136037A2
The method, object of the present invention, concerns the peracylation of oleuropein and its products of hydrolysis: The method makes use of the excellent properties as Lewis acid catalysts of halides and tryphilates of lanthanides (III)...  
WO/2008/068593A3
Polymorphs of a motilide having a structure represented by formula (Ia).  
WO/2008/126752A1
A skin-lightening agent containing a novel skin-lightening ingredient as an active ingredient. The active ingredient comprises equol and/or an equol glycoside formed by bonding one or more glycosyl groups to one or more of the hydroxy gr...  
WO/2008/125683A1
There are described a derivative of Vitamin E capable of binding with the fibres of a fabric and gradually releasing Vitamin E by contact with the skin, the aforesaid fibres and the fabrics and garments produced therewith.  
WO/2007/115278A3
The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof, which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comp...  
WO/2008/119543A1
The invention relates to a polymorphous form of clarithromycin (form V) as well as the production and use thereof.  
WO/2008/032105A3
A compound having: a bicyclic ring structure that comprises two fused six-membered carbon rings, wherein one of the rings is aromatic, and wherein one carbon in the bicyclic ring structure may optionally be replaced with a nitrogen, sulf...  
WO/2008/019240A3
The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof, which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions com...  
WO/2008/019784A3
Disclosed are novel avermectin derivatives of formula (I), wherein -C22R1-A-C23R2, R3, R4, and R5 have the meanings indicated in the description, methods for producing said substances, the use thereof for controlling animal pests, novel ...  
WO/2008/111020A2
The present invention provides macrolide derivatives, which can be used as antibacterial agents. Compounds disclosed herein can be used for treating or preventing conditions caused by or contributed to by gram positive, gram negative or ...  
WO/2008/110918A2
The invention relates to compounds of Formula (I) wherein R1, R2, and X are as defined herein. The invention also relates to pharmaceutical compositions and methods of treating bacterial infections using compounds of Formula (I).  
WO/2008/011588A3
Bromoglufosfamide and related compounds are useful in the treatment of cancer and other hyperproliferative diseases. Glufosfamide and bromoglufosfamide are synthesized by reacting the corresponding tetracetyl derivatives with MeOH and a ...  
WO/2008/028050A3
The present invention relates to methods of use of glycosyltransferases and related novel compounds. The invention exploits the reversibility of glycosyltransferases to generate new sugars, unnatural biomolecules and numerous one-pot rea...  
WO/2008/106224A1
The present invention provides triazole macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, antiproliferative, anti-inflammatory, and prokinetic agents.  
WO/2008/106226A2
The present invention provides triazole macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO/2008/099368A1
The present invention provides macrolide derivatives, which can be used as antibacterial agents. Compounds disclosed herein can be used for treating or preventing conditions caused by or contributed to by gram positive, gram negative or ...  
WO/2008/091554A1
The invention relates to novel forms of compounds displaying broad spectrum antibiotic activity, especially crystalline polymorphic forms and amorphous forms of such compounds, compositions comprising such crystalline polymorphic forms a...  
WO/2008/089669A1
The present invention relates to novel pharmaceutical compositions comprising Epimedium wushanense Ying extracts, their methods of preparation, and their use in inhibiting thrombosis and lipid deposition. Also provided by the present inv...  
WO/2008/091518A1
The present invention is related to pharmaceutical compositions of one or more tiacumicins that exhibit improved stability, and methods of treatment using such formulations. The formulations contain one or more tiacumicins, such as difim...  
WO/2008/088047A1
Disclosed is a method for producing a glycoside of a flavonoid, which comprises the step of reacting the flavonoid and a sugar donor with an enzymatic agent having a glycosylation activity and derived from a bacterium belonging to the ge...  
WO/2008/060767A3
Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and ...  
WO/2008/084498A1
A process is described in which decolorization of solutions or reaction mixtures containing trichlorogalactosucrose or 6-acetyl trichlorogalactosucrose is achieved described by bubbling ozone. The method can be used at various stages in ...  
WO/2008/083200A2
Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using...  
WO/2008/072034A1
The present invention relates to macrolide derivatives of formula (I) in which R1 and R2 have the meanings given in the description; which are endowed with antiinflammatory activity and are substantially free of antibiotic properties, to...  
WO/2008/068593A2
Polymorphs of a motilide having a structure represented by formula (Ia).  
WO/2007/051604A3
The invention relates to novel 2,4-dichlorophenoxy acetic acid derivatives for coupling to carrier molecules and solid phases. The compounds are can be used, among other things, for marking biomolecules in biolanalytical applications. A ...  

Matches 451 - 500 out of 6,658