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Matches 1,001 - 1,050 out of 6,641

Document Document Title
WO/2004/000866A1
There are described 11-C-substituted derivatives of clarithromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptabl...  
WO/2003/105766A2
The present invention is directed to novel compounds and compositions that have Rsk specific inhibitory activity. In addition, inhibition of Rsk by the present compounds has been discovered to halt the proliferation of cancer cell lines ...  
WO/2003/106413A2
A process for preparing N-(substituted)-C­- (substituted methyl)-oxazolidinones, C-(substituted methyl)-oxazolidinones, and N-(substituted)-C­- (substituted ethyl)-oxazolidinones, preferably chiral, from optically active C-(protected o...  
WO2003089446A3
There are described novel 5-0-mycaminosyltylonide (OMT) analogs of Formula (I) possessing increased antibacterial activity toward Gram positive and Gram negative bacteria as well as macrolide resistant Gram positives and pharmaceutically...  
WO2003053988A3
A compound of formula (I) wherein the bond marked by formula (II) indicates either the S or the R isomer at the 4''-position; and wherein R1 is C1-C12alkyl, C3-C8cycloalkyl; or C2-C12alkenyl; R2 is, for example, hydrogen, unsubstituted o...  
WO/2003/102009A1
A method for preparing high purity azithromycin is described characterised in that the intermediate 9a-deoxo-9a-aza-9a-homoerythromycin A is crystallised and obtained at very high purity, the subsequent methylation reaction effected on s...  
WO/2003/101466A1
From the viewpoints of enhancing glutathione synthesizability in cells as a means which is different from the method of supplying a precursor amino acid used in the biosynthesis of glutathione or to be used together with the above method...  
WO2003079980A3
Disclosed are caboxylic acid glycuronides, glycosamides and glycosides of quinolones, penicillins and analogs thereof to treat conditions and diseases such as bacterial infections.  
WO/2003/102010A1
3-Descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents of the formula: (I) wherein R1, W, R3, R4, R5, R6, X, X', and Z are as described herein and in which the substituents have the meaning indicated in the descri...  
WO/2003/099306A1
The present invention relates to a process for preparing apigenin-7-O-b-D-glucuronide(AGC) isolated from Clerodendron trichotomum Folium and a pharmaceutical composition comprising above compound for the prevention and treatment of gastr...  
WO/2003/099307A1
The present invention relates to process for preparing quercetin-3-0-¥â-D-glucuronide(QGC) isolated from Rumex Aquaticus herba leaves and a pharmaceutical composition comprising above compound for the prevention and treatment of gastri...  
WO2003068790A3
Antibacterial compounds having formula (I), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxi...  
WO2003017949A3
Novel synthetic gangliosides and pharmaceutical compositions containing such synthetic gangliosides are described. Methods of making the novel synthetic ganglioside compounds and compositions as well as their use in the field of neuropro...  
WO2002068441A3
What is described are a compound of formula (I) in which, R1 is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; R2 is H, unsubstituted or mono- to pentasubstituted C1-C12alkyl or unsubstituted or mono-to pentasubstituted C1-C12alkenyl; R3...  
WO/2003/097659A1
The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions com...  
WO/2003/094911A1
A method for treating and/or preventing hepatic disease conditions in mammals including human beings, said method comprising the steps of administering to the mammal an effective amount of 10-O-p-hydroxybenzoylaucubin compound of Formula...  
WO/2003/095468A1
A compound of formula (I); that has the S-configuration at the 4'-position and wherein the bond between carbon atoms 22 and 23 is a single or a double bond; R1 is C1-C12alkyl, C3-C8cycloalkyl; or C2-C12alkenyl; R2 is H, or, for example, ...  
WO/2003/094946A1
ABSTRACT: The present invention provides a method for treating and/or preventing hepatic disease conditions in a subject mammals including human beings, said method comprising the steps of administering to the mammal an effective dosage ...  
WO/2003/095466A1
The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comp...  
WO/2003/094842A2
Disclosed are conjugates comprising a central nervous system-active drug linked through an amide bond to a glucuronic acid or glucosamine moiety, and uses thereof, e.g., for treating or ameliorating central nervous system diseases or dis...  
WO/2003/093288A1
Antibacterial compounds with improved pharmacokinetic profiles having formula (I), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing th...  
WO/2003/093289A1
Antibacterial compounds having formula (I) and formula (II), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and metho...  
WO/2003/093286A1
Methods are described for the preparation of combinatorial libraries of potentially biologically active disaccharide compounds. These compounds are variously functionalized, with a view to varying lipid solubility size, function and othe...  
WO/2003/092410A1
A method for producing a rutin-containing extract from mature buckwheat using a water culture system is provided. The method includes germinating a buckwheat seed, growing the buckwheat seed into mature buckwheat which contains the great...  
WO/2003/090679A2
Antibacterial compounds having formula (I) and formula (II), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and metho...  
WO/2003/090761A1
Antibacterial compounds having formula (I), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxi...  
WO2002057286A3
Compounds of formula (I), and formula (II), or therapeutically acceptable salts or prodrugs thereof are useful as antibacterial agents. Methods to make the compounds, compositions containing the compounds, and methods of treatment using ...  
WO/2003/090760A1
Antibacterial compounds having formula (I) and formula (II), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates employed in the processes, compositions containing the compounds, and m...  
WO/2003/088907A2
The invention provides new isoflavonoid and triterpenoid compounds isolated from a soybean phytochemical concentrate. The new compounds have exhibited cytotoxic activity against selected tumor cells lines. Pharmaceutical compositions com...  
WO/2003/089447A1
There are described novel 5-O-mycaminosyltylonide derivatives of formula (I) and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically...  
WO2003011881A3
Glucoside and glucuronide derivatives ofhydromorphone, dihydromorphine, and dihydroisomorphine and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising a glucoside or glucuronide derivative ofhydromorphone, d...  
WO/2003/089446A2
There are described novel 5-0-mycaminosyltylonide (OMT) analogs of Formula (I) possessing increased antibacterial activity toward Gram positive and Gram negative bacteria as well as macrolide resistant Gram positives and pharmaceutically...  
WO/2003/086394A1
The present invention is directed to compounds comprising a 2,3-diphenylquinoxaline moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containin...  
WO/2003/082887A1
The present invention relates to a novel compound 8-(C-β-D-glucopyranosyl)-7,3', 4'- trihydroxyflavone, isolated from Pterocarpus marsupium useful in the treatment of diabetes. The present invention also relates to a method for the prep...  
WO/2003/082889A1
Azithromycin is prepared in a high yield by a simple process using a crystalline 9-deoxo-9a-aza-9a-homoerythromycin A hydrate.  
WO/2003/082888A1
A process for enriching the relative concentration of genistin from a mixture of isoflavones is described. In accordance with one aspect of the invention, the process comprises providing a material containing a mixture of isoflavones, ex...  
WO/2003/080582A2
The invention relates to novel fredericamycin derivatives, to drugs containing said derivatives or the salts thereof, and to the use of the fredericamycin derivatives for treating diseases, especially cancer diseases.  
WO/2003/080600A1
The invention refers to a process to obtain lignans, especially to obtain cubebin and methylpluviatolide from leaves of Zanthoxylum naranjillo or Piper cubeba. It also refers to a process to obtain semi-synthetic derivatives of cubebin, ...  
WO/2003/080074A1
Disclosed are glycoside and orthoester glycoside derivatives of apomorphine and analogs thereof to treat conditions and diseases such as erectile dysfunction.  
WO/2003/080593A1
The present invention discloses conjugates of polyethylene glycol and flavonoid drugs, wherein said conjugates the flavonoids, such as puerarin, daidzein, baicalein and baicalin, were modification by PEGylation, in order to increase wate...  
WO/2003/079980A2
Disclosed are caboxylic acid glycuronides, glycosamides and glycosides of quinolones, penicillins and analogs thereof to treat conditions and diseases such as bacterial infections.  
WO/2003/080637A1
The present invention relates to a process of isolation of bioactive eupalitin (3-$g(o)-$g(b)-D-galactopyranoside) of formula (1) possessing anti-osteoporosis activity by extraction of powdered leaves of Boerhavia diffusa, with better yi...  
WO2003018031A3
The present invention relates to a method of treating respiratory infections in humans by administering a single dose of azithromycin.  
WO/2003/080075A1
An ameliorant for the chemical treatment of cancer which contains a chromanol glycoside represented by the following general formula (1): (1) wherein R1, R2, R3, and R4 are the same or different and each represents hydrogen or lower alky...  
WO/2003/077830A2
Substantially pure isostructural pseudopolymorphs of 9-deoxo-9a-aza-9a-methyl-9a- homo erythromycin A having the Formula I: wherein S is an organic solvent which is at least partially miscible with water, x is 1, 1.25, 1.5 or 2, y is 0, ...  
WO2003068171A3
A method of treating inflammation, an inflammatory condition, or AIDS-associated neurological disorder in a subject in need of such treatment is disclosed. The method includes administering to said subject a pharmaceutically effective am...  
WO2002083700B1
Provided are compounds and compositions thereof that are useful for treating inflammation, particularly pulmonary inflammations including asthma and asthma-related pathologies such as allergy. Also provided are methods for using such com...  
WO/2003/072121A1
The invention provides an antiobestic and/or antidiabetic agent containing cyanidin 3-glucoside as an active ingredient. Thereby the increase of adipose cells can be suppressed and the blood glucose level can be reduced safely and effect...  
WO/2003/072588A1
The invention provides new macrolides antibiotics of formula I with improved biological properties, wherein R1 is hydrogen, cyano or a residue -Y-X-Q; Y is S, SO, S02, NH, NCH3, CH20, CH2NH, CH2N(CH3) or CO; X is a bond or a linear group...  
WO2002079465A3
An isolated gene cluster of Micromonospora echinospora which codes for calicheamicin biosynthesis. The biosynthetic gene cluster contains genes encoding proteins and enzymes used in the biosynthetic production of calicheamicin, including...  

Matches 1,001 - 1,050 out of 6,641