Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1,101 - 1,150 out of 6,645

Document Document Title
WO/2003/024984A1
Novel polysaccharides comprising one or more oxime linkages are provided. Methods for their preparation include the polycondensation of saccharides bearing oxime-forming substituents. In some embodiments, polymerization is conducted in t...  
WO/2003/024986A1
6-O-Carbamate-11,12-lacto-ketolide antimicrobials of the formula (I) wherein R1, R2, R3 R7, and R8 are as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibac...  
WO/2003/022844A2
The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provide...  
WO/2003/020236A2
The present invention relates to a natural extract from fungus, cyanobactria, plants, lichens or a mixture thereof having an ultra violet absorbency in the range of 220 nm to 425 nm wherein said extract is obtained by contacting said fun...  
WO/2003/020737A1
A compound of formula (I), wherein A is CH¿2? or (CH¿2?)¿2?; R?1¿ is hydrogen, arylalkyl, alkenyl, or alkyl; R?2¿ is alkyl or perfluoroalkyl; and R?3¿ and R?4¿ are as defined herein. Further provided are methods of using such comp...  
WO/2003/017949A2
Novel synthetic gangliosides and pharmaceutical compositions containing such synthetic gangliosides are described. Methods of making the novel synthetic ganglioside compounds and compositions as well as their use in the field of neuropro...  
WO2001063539A3
The invention relates to novel methods for using macrolide anti-infective agents. The macrolide anti-infective agents demonstrate antibacterial activity against multi-drug resistant strains of bacteria and, in particular, methicillin-res...  
WO2002050093A3
An efficient deoximation technique for use in synthesis of erythromycin derivatives, involving aryl thioimine intermediates is disclosed. The aryl thioimine intermediates can be utilized in a method for protecting a ketone of a ketone-co...  
WO/2003/018031A2
The present invention relates to a method of treating respiratory infections in humans by administering a single dose of azithromycin.  
WO2002064092A3
The present invention relates to in vitro methods for evaluating compounds that better correlate with therapeutic efficiency than evaluating compounds based on potency alone. In general, the inventive methods comprises: (i) determining a...  
WO/2003/014135A1
The present invention relates to a novel process for the preparation of acarbose. Said process comprises the steps of: 1) acidifying a fermentation broth containing an acarbose; 2) removing particulates from the fermentation broth; 3) ad...  
WO/2003/014136A1
11a−Azalide compounds represented by the following general formula (1) or pharmaceutically acceptable salts thereof: (1) wherein R1 represents hydrogen, C1−10 alkyl, etc.&semi R2represents hydrogen, hydroxy, etc.&semi R3 represents h...  
WO/2003/011879A1
$i(In vitro)/cell-free process of preparing a sialylated oligosaccharides are described. The sialylated oligosaccharides include gangliosides. The oligosaccharides linked to various moieties including sphingoids and ceramides. Novel comp...  
WO/2003/011882A1
There are described novel 4'-substituted 16-membered macrolides and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable c...  
WO/2003/011881A2
Glucoside and glucuronide derivatives ofhydromorphone, dihydromorphine, and dihydroisomorphine and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising a glucoside or glucuronide derivative ofhydromorphone, d...  
WO/2003/010178A1
The invention concerns disaccharides of formula (I) derived from $g(a)-maltosyl fluoride, wherein R?1¿ and R?2¿ are such as defined in Claim 1. Said disaccharides are useful as glycosyl donors in transglycosylation reactions catalysed ...  
WO/2003/010155A1
The invention relates to a method for producing novel spinosyn derivatives, which are substituted in the C-21 position by a 1-hydroxy-ethyl radical, to novel spinosyn derivatives of this type per se and to their use for producing novel s...  
WO/2003/010116A2
The invention provides compositions and methods for isolating phenolic compounds, particularly isoflavones, from aqueous extracts of plant materials that contain such compounds. The process comprising: (a) providing an aqueous plant extr...  
WO/2003/010240A1
A process for modifying the taste and/or odour properties of a food colouring substance having unpleasant taste and/or odour properties is disclosed. Secondly, there is provided a process for obtaining a blue non-bleeding colour that see...  
WO2002060436A3
This invention provides a method for treating a Pin1-associated state in a subject including administering to a subject an effective amount of a fredericamycin A compound such that the Pin1-associated state is treated. In another aspect,...  
WO/2003/004059A1
Use of an anti-parasitic agent in a sustained release form in the treatment of ectoparasitic infections.  
WO/2003/004509A2
Antimicrobial macrolide compounds are provided having formulas II: as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections ...  
WO2002032916A3
The present invention provides novel sixteen-membered macrolide compounds that are useful as anti-infective agents or as intermediates thereto. The present invention also provides methods for the preparation of these compounds, and metho...  
WO/2003/000674A1
It is intended to provide a process for producing a soluble isoflavone−containing composition, which is in a natural state free from any solubilizers or chemical modification, has a high solubility under neutral to acidic conditions an...  
WO2002009699A3
The present invention relates to methods of treating conditions and/or symptoms related to common cold of the upper and/or lower respiratory tract and/or eyes. In particular the invention relates to the methods of treating conditions and...  
WO/2003/000712A1
A nitrogenous heterocyclic derivative represented by the general formula (I), a pharmacologically acceptable salt thereof, or a prodrug of either. These have excellent human SGLT2 inhibitory activity and are useful as a preventive or rem...  
WO2002032918A3
The present invention includes compounds of the formula wherein: X is hydrogen or halide; R<2> is hydrogen, acyl, or a hydroxy protecting group; R<6> is hydrogen, hydroxyl, or -OR wherein R is a substituted or unsubstituted moiety select...  
WO2002087596A3
The invention relates to the use of 9-deoxo-9-dihydro-9a-methyl-9a-aza-9a-homoerythromycin. A (generic name: azithromycin) for the therapy of neutrophil-dominated non-infective inflammatory diseases, pharmaceutical compositions containin...  
WO/2003/000711A1
This invention provides analogs of eleutherobin and the eleuthesides modified at the C-11 position or comprising an epoxide functionality from C-11 to C-12. C-11 to C-12 is an ideal location for conjugating functional moieties to the ele...  
WO/2002/102818A1
A process for the preparation of erythromycin compounds by alkylating 2’−O−acetyl−4”−O−formyl−11−oxo−8,9−anh ydro− erythromycin A 6,9−hemiketal compound (1), characterized by reacting compound (1) with an alkyla...  
WO/2002/102819A1
A process for the preparation of 2’−O−acetyl−4”−O−formyl −8,9−anhydroerythromycin A 6,9−hemiketal compound (4), characterized by reacting 2’−O−acetylerythromycin A compound (2) with a fomylating agent to obtain ...  
WO/2002/098893A1
A glucopyranosyloxypyrazole derivative represented by the following general formula (I), a pharmaceutically acceptable salt of the derivative, or a prodrug of either. (I) The compound has excellent inhibitory activity against human SGLT1...  
WO/2002/097082A2
The complete DNA sequence of the gene cluster encoding the polypeptides responsible for the biosynthesis of the polyene antibiotic amphotericin of S. nodosus is provided. Engineered alteration of the amphC) gene so as to eliminate produc...  
WO/2002/096922A1
An efficient arylation technique for use in the synthesis of erythromycin derivatives, involving a modified Heck reaction which employs less than six mole percent of palladium catalyst and no phosphine is disclosed. With this modified He...  
WO/2002/097062A2
Recombinant DNA compounds that encode all or a portion of the narbonolide polyketide synthase are used to express recombinant polyketide synthase genes in host cells for the production of narbonolide, narbonolide derivatives, and polyket...  
WO/2002/094193A1
Methods for inhibiting angiogensis are disclosed the comprise administering oleouropein and/or the products of its hydrolysis in therapeutically effective amounts. The methods and compositions of the present invention are particularly ef...  
WO/2002/094843A1
The invention relates to novel crystal forms of azithromycin, and antibiotic useful in the treatment of infections.  
WO2002036601A3
The present invention relates to a novel glycosidation process to make intermediates useful in the preparation of indolopyrrolocarbazole derivatives which inhibit the growth of tumor cells and are therefore useful in the treatment of can...  
WO/2002/094861A2
Five protein families cooperate to form the warhead structure that characterizes enediyne compounds, both chromoprotein enediynes and non-chromoprotein enediynes. The protein families include a polyketide synthase and thioesterase protei...  
WO/2002/092111A1
The invention relates to extracts from the iris plant, Belamcanda chinensis, for the production of a pre-formulated agent suitable for the selective treatment and/or prophylaxis of diseases of the urogenital tract caused by sex hormones....  
WO/2002/092614A1
The invention relates to novel compounds having formula (I) in which: R¿1?, R¿?2 and R¿3? are identical or different and each represent independently: - a (C¿1?-C¿6?)alkyl group, - a pyridinyl group, or a -CH¿2?-NR¿4?R¿5? group i...  
WO2001092341A8
This invention provides an hexaglucal compounds of formula (III), which is a new kind of bio-pesticide. And also provides the processes for preparing them, which include the regioselective reaction of compounds presented by formula (I) a...  
WO/2002/087596A2
The invention relates to the use of 9-deoxo-9-dihydro-9a-methyl-9a-aza-9a-homoerythromycin. A (generic name: azithromycin) for the therapy of neutrophil-dominated non-infective inflammatory diseases, pharmaceutical compositions containin...  
WO/2002/087632A1
The invention relates to a wide variety of different methods and compositions that find use in high throughput screening applications utilizing magnetic resonance imaging (MRI) contrast agents.  
WO/2002/088158A1
The invention relates to processes for preparing compounds of formula (3) wherein R?4¿ is as defined herein, and to pharmaceutically acceptable salts thereof, as well as intermediates useful in such processes. The compounds of formula (...  
WO/2002/088157A1
The pyrazole derivatives represented by the following formulae or analogues of these. They are usable as an antidiabetic agent. (1)  
WO2002051855A3
The present invention provides novel macrolide compounds of the formulas for the treatment of gastrointestinal motility disorders.  
WO/2002/085898A1
A clathrate of azithromycin hydrate with 1,2-propyleneglycol is much less hygroscopic than azithromycin hydrate or crystals known in the art, therefore, it can be useful for the preparation of a medicine for treating various microbial in...  
WO2002015842A3
The present invention provides a stable form of azithromycin derivatives that act as antibiotics. These compounds are in anhydrous form and have increased stability over the hydrated forms.  
WO2002042315A3
Azithromycin in the form of a monohydrate comprising from 4.0 % to 6.5 % of water, a process for its preparation and its use in pharmaceutical compositions.  

Matches 1,101 - 1,150 out of 6,645