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Matches 351 - 400 out of 6,631

Document Document Title
WO/2011/009938A3
The present invention relates to Stambomycin compounds, their derivatives and their pharmaceutically acceptable salt thereof.  
WO/2011/048148A2
This invention relates to compounds represented by formula (I) wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes...  
WO/2011/027790A1
Provided is a powder containing anhydrous crystals of ascorbic acid 2-glucoside, said powder being significantly less prone to caking than existing general-purpose quasi-drug-class powders containing anhydrous crystals of ascorbic acid 2...  
WO/2011/023754A1
The invention relates to crystalline hydrates of the formula (I) in which n has a value of from 2.1 to 2.5. The compound is suitable, for example, as an antidiabetic.  
WO/2011/023755A1
A process for preparing pyrazole-glycoside derivatives of the general Formula (I) in which the meanings are R1 H and R2 F; or R1 F and R2 H; or R1 F and R2 F; R3 (C1-C8)-alkyl, where one, more than one or all hydrogen(s) may be replaced ...  
WO/2010/003319A8
The invention provides macrolide derivatives, the preparation and the use thereof. The macrolide derivatives of the present invention are hydrates of erythromycin salts, their formula is C37H67NO13·A·nH2O, n=1.0-11.0, A is selected fro...  
WO/2011/017998A1
Gambogic acid cyclization analogues with formula I, II and III are disclosed, wherein cycles A, B and C are saturated or unsaturated alicyclic, alicyclic heterocyclic, aromatic ring or aromatic heterocyclic groups containing 4-10 members...  
WO/2011/018510A1
The invention relates to macrolide compounds of formula (I), the use of said compounds as medicaments, in particular for the treatment or prevention of inflammatory and allergic diseases, pharmaceutical compositions containing said compo...  
WO/2011/016260A1
Disclosed is a glycosyl donor reagent comprising a glycosyl donor compound other than a sugar nucleotide. Also disclosed is an enzyme capable of catalyzing a glycosyltransfer reaction that utilizes a glycosyl donor compound other than a ...  
WO/2011/015219A1
The present invention relates to methods for improving the purity of azithromycin, preferably by purifying azithromycin from degradation products and/or isomers. The invention describes a degradation product of azithromycin which may be ...  
WO/2011/013735A1
Disclosed is a novel antibacterial agent. Specifically disclosed is a novel antibacterial agent which can exert an effective action on various resistant bacteria such as VSSA, MRSA, VISA, VRE and VRSA. A novel flavanone derivative having...  
WO/2011/009938A2
The present invention relates to Stambomycin compounds, their derivatives and their pharmaceutically acceptable salt thereof.  
WO/2010/122571A3
A process for selective methylation at 6 position of erythromycin A derivatives.  
WO/2009/156938A3
The present invention relates to an improved process for the preparation of 6,9-imino ether of formula (I) an intermediate used in preparation of Azithromycin. The present invention further provides a process for preparation of Azithromy...  
WO/2010/081163A3
Method for selective 2-sulfation of glycosides.  
WO/2010/138608A1
The present invention provides methods for improving the production of recombinant proteins through the use of pharmacological chaperones for the recombinant proteins. As exemplified by the present invention, the binding of a pharmacolog...  
WO/2010/136971A1
The invention relates to ketolide compound of Formula (I) and the pharmaceutically acceptable salts thereof having antimicrobial activity. The invention also provides pharmaceutical compositions containing the compounds of invention and ...  
WO/2010/123383A1
The invention provides a method for in vitro formation of anthocyanic vacuolar inclusion (AVI)-like structures, the method comprising the step of combining at least one anthocyanin, and b) at least one lipid. The invention also provides ...  
WO/2010/116834A1
A plant containing a C-glucosyl flavonoid, which is a compound having an excellent physiological activity, at a high content is found among plants that are readily available and highly safe from the viewpoint of oral ingestion, and an or...  
WO/2010/107793A1
This present provides kaempferol-3-(2-E,3-Z-di-p-coumaroyl)-rhamnoside, kaempferol- 3-(2-Z-3-E-di-p-coumaroyl)-rhamnoside, and kaempferol-3-(2,3-di-Z-p-coumaroyl)-rhamnoside compounds useful as a new class of anti-bacterial agents. These...  
WO/2010/100933A1
Disclosed is a novel ingredient having an anti-obesity activity and a diabetes-ameliorating activity, which is obtained by focusing on a plant Albizzia julibrissin Durazz. Specifically disclosed are an anti-obesity agent and a diabetes-a...  
WO/2010/096650A1
The disclosure provides novobiocin analogues with noviose replacements which are useful as Hsp90 inhibitors in the treatment of cancer.  
WO/2010/092592A2
The process of preparation of pure diosmin that is independent of hesperidine used for conversion is described. Process is effective in controlling the impurity by crystallization. The cost effective and ecofriendly process enables recov...  
WO/2009/065287A8
The present invention provides a mangiferin calcium and its preparation and use. The mangiferin calcium can lower plasma insulin, glucose, lipid, and also can improve the solubility and oral bioavailability of mangiferin and increase ins...  
WO/2010/086350A1
2'-0-substituted 14- or 15-membered azalide macrolides of Formula (I) wherein R6 represents (i) -C1-8alkyl, unsubstituted or substituted at the terminal carbon atom by a group selected from hydroxy, -C1-3alkoxy and -C(O)OC1-3alkyl, or wh...  
WO/2010/088192A1
A catheter lock composition for preventing bacterial infection having an effective amount of glycerol and sodium chloride solution. The effective amount of glycerol is between about 35-60% and sodium chloride is in a concentration range ...  
WO/2010/086349A1
The compound 3'-N-demethyl-4"-O-(2-diethylaminoethanoyl)-6-O-methyl-9a-az a-9a- homoerythromycin A, having the Formula (I): or a salt thereof, compositions comprising the compound, its use in the treatment of neutrophil dominated inflamm...  
WO/2010/086351A1
The present invention relates to novel 3'-N-substituted 9-deoxo-9a-methyl-9a-aza-9a- homoerythromycin A derivatives having antimalarial activity. More particularly, the invention relates to 3'-N-substituted-9-deoxo-9a-methyl-9a-aza-9a-ho...  
WO/2010/082600A1
Disclosed is an agent for maintaining the healthy state of the gum, maintaining the healthy state of the gingival, maintaining the healthy state of tissues that support teeth, preventing, treating or ameliorating periodontal diseases, ma...  
WO/2010/081163A2
Method for selective 2-sulfation of glycosides.  
WO/2010/045755A8
Glycosyl-derivatives of puerarin presented by formula (I) or pharmaceutically acceptable salts thereof, wherein R is monosaccharides (6-carbon saccharides or 5-carbon saccharides) or oligosaccharyl (2-5 glycosyl selected from 6-carbon sa...  
WO/2010/067010A2
The invention relates to derivatives of morphine-6-glucuronide having formula (I) wherein R1 is a 5-membered heteroaromatic group optionally substituted by one or more substituents selected from among halogen atoms and (C1-C4)alkyl, halo...  
WO/2010/066690A1
The invention relates to a crystalline hydrate of the formula (I) in which n has a value of from 0.9 to 1.1. The compound is suitable, for example, as an antidiabetic.  
WO/2010/068601A1
A novel crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof. The invention relates to a crystalline hydrate of the formula (I) in which n has a value of from 0....  
WO/2010/067008A2
The invention relates to compounds having formula (I) wherein: R1 represents a hydrogen atom or a (C1-C4)alkyl group; R2 represents a hydroxyl group, a thiol group, a (C1-C4)alkyloxy group or a thio(C1-C4)alkyl group; and n is an integer...  
WO/2010/068605A1
The present invention is directed to stable polymorphic forms of the compound of formula Il and hydrates thereof: i. e., a solvent free polymorph "C" of 4-[(4-methoxyphenyl)methyl]-5-(trifluoromethyl)- 1H-pyrazole-3-yl]-4-deoxy-4-fluoro-...  
WO/2010/067007A2
The invention relates to a method for preparing morphine-6-glucuronide or one of the derivatives thereof, comprising the following steps: (i) reacting a compound having formula (I), wherein R1 represents a carbonyl group, COR5CO or S02R6...  
WO/2010/065852A1
This invention provides for novel antiparasitic and pesticidal derivatives of avermectin and milbemycin compounds in which two avermectin or milbemycin members are linked together by a chemical linker. The resulting compounds may be used...  
WO/2010/048786A1
The present invention provides an erythromycin crystallizing method, which comprises using dichloromethane containing solvent as a preparation solvent, and the dichloromethane solution of erythromycin received was gradiently cooled from ...  
WO/2010/045755A1
Glycosyl-derivatives of puerarin presented by formula (I) or pharmaceutically acceptable salts thereof, wherein R is monosaccharides (6-carbon saccharides or 5-carbon saccharides) or oligosaccharyl (2-5 glycosyl selected from 6-carbon sa...  
WO/2010/048486A1
The present invention relates to methods for synthesizing macrolide compounds which are known to have antibacterial activity, and are useful in the therapy of bacterial infections in mammals. More specifically, the invention relates to m...  
WO/2010/043049A1
The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides having a hydrolyzable covalent bond to a therapeutic agent that includes, etoposide, etoposide 4'- dimethylglyc...  
WO/2010/041290A1
A natural molecule extracted from a citrus fruit characterized by the fact that its structure is a flavonoid linked to 3-hydroxy-3-methyl glutaric acid and an extraction process in which: the extraction of chopped fruit is conducted in p...  
WO/2010/040252A1
Epothilone glycoside compounds having structures shown in formula (I) or (II), and pharmaceutical compositions containing an effective amount of the epothilone glycoside compounds and pharmaceutically acceptable carriers, which can be us...  
WO/2010/038842A1
Disclosed is a compound represented by formula (I) [wherein the symbols are as defined in the description]. Also disclosed is a process for producing the compound. The compound has a lipase-inhibiting activity, and is therefore useful ...  
WO/2010/029913A1
Disclosed is a mental vigor improver which can improve diminished mental vigor caused by stress or mental fatigue, can also improve diminished volition, diminished attention/concentration, decreased workability or the like, and is safe f...  
WO/2010/027108A1
Disclosed are a method for sensing saccharide-binding protein easily, quickly, and with high sensitivity, and a fluorescent compound necessary for this sensing. Specifically, disclosed is a method for sensing saccharide-binding protein t...  
WO/2010/016587A1
Disclosed is a method for accurately evaluating the specific incorporation of D-glucose into cells. The method is characterized by: contacting each of a D-glucose derivative that can be incorporated into cells specifically and has a flu...  
WO/2003/061603A9  
WO/2010/006982A1
The present invention is directed to sulfated oligosaccharides having 4, 5 or 6 saccharidic units and wherein a glycosidic bond between two saccharide units is substituted by a C-C bond, and wherein the sulfation degree expressed as perc...  

Matches 351 - 400 out of 6,631