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Matches 401 - 450 out of 6,641

Document Document Title
WO/2010/029913A1
Disclosed is a mental vigor improver which can improve diminished mental vigor caused by stress or mental fatigue, can also improve diminished volition, diminished attention/concentration, decreased workability or the like, and is safe f...  
WO/2010/027108A1
Disclosed are a method for sensing saccharide-binding protein easily, quickly, and with high sensitivity, and a fluorescent compound necessary for this sensing. Specifically, disclosed is a method for sensing saccharide-binding protein t...  
WO/2010/016587A1
Disclosed is a method for accurately evaluating the specific incorporation of D-glucose into cells. The method is characterized by: contacting each of a D-glucose derivative that can be incorporated into cells specifically and has a flu...  
WO/2003/061603A9  
WO/2010/006982A1
The present invention is directed to sulfated oligosaccharides having 4, 5 or 6 saccharidic units and wherein a glycosidic bond between two saccharide units is substituted by a C-C bond, and wherein the sulfation degree expressed as perc...  
WO/2009/105507A3
This present disclosure provides methods of treating pain with beloxepin, beloxepin enantiomers, and analogs thereof.  
WO/2010/003319A1
The invention provides macrolide derivatives, the preparation and the use thereof. The macrolide derivatives of the present invention are hydrates of erythromycin salts, their formula is C37H67NO13·A·nH2O, n=1.0-11.0, A is selected fro...  
WO/2009/156938A2
The present invention relates to an improved process for the preparation of 6,9-imino ether of formula (I) an intermediate used in preparation of Azithromycin. The present invention further provides a process for preparation of Azithromy...  
WO/2009/146052A2
A process for the purification of sucralose in sucralose-containing feed streams is disclosed. The process includes multiple liquid-liquid extraction steps; optionally, a concentration step; multiple crystallization steps; optionally, a ...  
WO/2009/139181A1
Disclosed is a 10a-azalide compound which is effective against a bacterium Haemophilus influenzae (an influenza bacterium) or an erythromycin-resistant bacterium (e.g., resistant pneumococcus or streptococcus) and has a novel structure. ...  
WO/2009/137737A2
The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit superior antibacterial properties, particularly against Haemophilus influenzae. The present inventi...  
WO/2009/130189A1
Novel 2 ' -O, 3 ' -/V-bridged macrolides useful in treatment of inflammatory diseases. More particularly, the invention relates to 2 ' -O, 3 ' -/V-bridged 14- membered macrolides and to 2 ' - O, 3 ' -/V-bridged 15-membered azalide macrol...  
WO/2009/128537A1
Disclosed is a heterocyclic compound which can be used as an antipsychotic agent having a broader therapeutic spectrum compared with known typical antipsychotic agents and known atypical antipsychotic agents, having few adverse side effe...  
WO/2009/128421A1
Disclosed is a novel form of 3-(3-{4-[3-(β-D-glucopyranosyl-oxy)-5-isopropyl-1H-pyrazole -4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethyl-propi onamide with improved storage stability. 3-(3-{4-[3-(β-D-glucopyranosyloxy)-5-isoprop...  
WO/2009/121495A1
Described is pentamycin in a purity exceeding 95%, certain polymorphs and solvates of pentamycin, processes for their manufacture, and a method for decreasing the rate of degradation of pentamycin.  
WO/2009/106419A1
The invention relates to macrolide compounds of formula (I),the use of said compounds as medicaments, in particular for the treatment or prevention of inflammatory and allergic diseases, pharmaceutical compositions containing said compou...  
WO/2009/102876A1
The invention provides compounds inhibitory to the Hepatitis C viral protease, compositions and combinations including the compounds, methods of treatment of conditions wherein inhibition of the Hepatitis C viral protease is medically in...  
WO/2009/100165A2
Disclosed is a method for separating anthocyanins depleted in phenolic mixture content from fruits or vegetables feedstock containing anthocyanins and phenolic mixtures. The first step is to contact the feedstock with a cation-exchange r...  
WO/2008/019784A8
Disclosed are novel avermectin derivatives of formula (I), wherein -C22R1-A-C23R2, R3, R4, and R5 have the meanings indicated in the description, methods for producing said substances, the use thereof for controlling animal pests, novel ...  
WO/2009/084612A1
Disclosed is a method for producing an eriocitrin-containing material, which comprises the steps of: extracting a citrus extract containing eriocitrin from a citrus fruit with an extraction solvent; and separating eriocitrin from the cit...  
WO/2009/084482A1
Disclosed is a means for promoting the absorption of a sesamin component in the body. The absorption of a sesamin component in the body can be promoted by using the sesamin component in combination with a quercetin glycoside.  
WO/2009/084531A1
The invention provides a novel form of 3-(3-{4-[3-(β-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4 -ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropiona mide with improved storage stability. Since bis[3-(3-{4-[3-(β-D-glucopyrano...  
WO/2009/075923A2
The present invention discloses compounds of formula I, II or, or pharmaceutically acceptable salts, esters, or prodrugs thereof: (formulas) which exhibit antibacterial properties. The present invention further relates to pharmaceutical ...  
WO/2009/065287A1
The present invention provides a mangiferin calcium and its preparation and use. The mangiferin calcium can lower plasma insulin, glucose, lipid, and also can improve the solubility and oral bioavailability of mangiferin and increase ins...  
WO/2009/064953A1
The invention provides methods utilizing bridged macrolide or tylosin derivatives for the treatment of patients with inflammatory bowel diseases. The methods of the invention provide for the administration to a patient of a therapeutical...  
WO/2008/068593A8
Polymorphs of a motilide having a structure represented by formula (Ia).  
WO/2007/080507A3
The invention relates to processes for the preparation of anhydrous azithromycin. The invention also relates to a one-pot process for the preparation of azithromycin without isolation of intermediates. The invention also relates to pharm...  
WO/2009/055557A1
Described herein are processes for the preparation of compounds of formula (I): and pharmaceutically acceptable salts, solvates, and hydrates thereof.  
WO/2009/053259A1
The present invention relates to a process for the preparation of erythromysin derivatives, in particular telithromycin of formula (I) and its pharmaceutically acceptable salts, providing the isolated intermediates in crystalline form of...  
WO/2007/078340A3
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and...  
WO/2009/021163A3
Described herein are methods of improving the efficiency of gene transfer for a wide range of applications. Specifically provided are methods of increasing expression of an exogenous gene in a cell by contacting the cell with a vector co...  
WO/2009/023191A3
The present invention includes a process involving a one-pot reaction for preparing erythromycin 9-oxime salt comprising: (a) reacting erythromycin thiocyanate with an ammonium source to obtain erythromycin free base; (b) oximating the C...  
WO/2009/049370A1
The invention relates to novel compounds that have utility as inhibitors of heparan sulfate-binding proteins; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic...  
WO/2009/004322A3
The present invention provides a compound of formula (I') which is a nystatin derivative having an additional double bond present between C28 and C29 and which is further modified relative to nystatin at one or more of positions C5, C7, ...  
WO/2008/023248A3
The present invention provides compounds having antimicrobial activity for preventing and treating diseases caused by microbial infections. Thus, the present invention relates to novel • semi-synthetic 11,12-γ lactone macrolides and k...  
WO/2009/046620A1
Provided is a method of preparing cycloastragenol monoglycoside CMG (cycloastragenol-6-O-beta-D-glucoside), which comprises the following steps of: a. using astragaloside IV or extracts of Radix Astragali by conventional method as materi...  
WO/2009/047992A1
It is intended to provide a novel UDP-glucuronyl transferase and a polynucleotide encoding the same (for example, a polynucleotide containing a polynucleotide comprising one nucleotide sequence selected from the group consisting of a nuc...  
WO/2008/059516A3
The invention is a novel process for purification of macrolides such as Tacrolimus using a new polymer resin and copper salts containing cupric ions. The novel polymer resin contains polyvinyl pyrrolidone, metha acrylate, divinyl benzene...  
WO/2009/043296A1
The invention discloses gambogic glycoside derivatives and analogs represented by formula I, the preparation and the application thereof, wherein the substituents R1-R12 are defined as in the description. The gambogic glycoside derivativ...  
WO/2005/039500A3
The present invention provides methods for the isolation of a new group of actinomycetes and for the identification of members of this group based on characteristic nucleotide sequences and phylogenetic analyses. This group is phylogenet...  
WO/2009/009906A8
A method for producing one or more than one isoflavonoid compound in a plant is described. The method comprises providing a production plant comprising one or more than one nucleotide sequence encoding isoflavone glycosyltransferase oper...  
WO/2009/013351A3
This invention relates to solvated and non-solvated crystalline forms of 20,23- dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from)such crystalline form...  
WO/2009/039177A1
The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: formula (I) which exhibit antibacterial properties. The present invention further relates to pharmaceutical comp...  
WO/2008/157751A3
The present invention provides substituted imidazoheterocyclic compounds having the structure of Formula (I) Also provided are pharmaceutically acceptable salts, acid salts, hydrates, solvates and stereoisomers of the compounds of formul...  
WO/2009/022009A1
The invention relates to a pharmaceutical composition according to claim 1 comprising a pyrazole-O-glucoside derivative in combination with a DPP IV inhibitor which is suitable in the treatment or prevention of one or more conditions sel...  
WO/2009/023196A1
Provided are compounds of formula (III) useful for modulation of immune responses, compositions comprising the compounds, and methods of use of such compositions for treating diseases or disorders involving an immune response. In certain...  
WO/2009/023191A2
The present invention includes a process involving a one-pot reaction for preparing erythromycin 9-oxime salt comprising: (a) reacting erythromycin thiocyanate with an ammonium source to obtain erythromycin free base; (b) oximating the C...  
WO/2009/021163A2
Described herein are methods of improving the efficiency of gene transfer for a wide range of applications. Specifically provided are methods of increasing expression of an exogenous gene in a cell by contacting the cell with a vector co...  
WO/2009/019868A1
Disclosed is a novel 10a-azalide compound crosslinked at position-10a and position-12, which is represented by the formula shown below and is effective against an influenza bacterium or an erythromycin-resistant bacterium (e.g., an eryth...  
WO/2009/016142A1
The present invention relates to novel 2'-O-substituted 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A derivatives having antimalarial activity. More particularly, the invention relates to 2'-O-substituted-9-deoxo-9a-methyl-9a-aza-9a-hom...  

Matches 401 - 450 out of 6,641