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Matches 501 - 550 out of 864

Document Document Title
JPH10506621A
PCT No. PCT/GB95/01955 Sec. 371 Date Apr. 14, 1997 Sec. 102(e) Date Apr. 14, 1997 PCT Filed Aug. 17, 1995 PCT Pub. No. WO96/08503 PCT Pub. Date Mar. 21, 1996A compound of formula (I) or salts thereof, where R0 is hydrogen or together wit...  
JPH10506605A
The present invention relates to a method of preparing BCH-189 and various analogues of BCH-189 from inexpensive precursors with the option of introducing functionality as needed. This synthetic route allows the stereoselective preparati...  
JP2769492B2
Deuterated aromatic aldehydes of the formula: where Ar is substituted phenyl, and derivatives thereof represented by the formula: where Ar is substituted or unsubstituted phenyl, and X1 and X2 are substituted hetero atoms or together wit...  
JPH10506413A
Methods and compositions are provided which increase the cellular uptake of bioactive materials by covalently bonding such compounds to carbohydrate moieties through chemical linkers using other than glycosidic bonds. Numerous carbohydra...  
JPH10501809A
PCT No. PCT/US95/06641 Sec. 371 Date Oct. 30, 1996 Sec. 102(e) Date Oct. 30, 1996 PCT Filed May 25, 1995 PCT Pub. No. WO95/35102 PCT Pub. Date Dec. 28, 1995A method for the preparation of 2'-modified nucleosides is provided. The method c...  
JPH10501527A
Staurosporin derivatives of formula (I), wherein R1 is an acyl radical having from 2 to 30 carbon atoms, an aliphatic hydrocarbon radical having up to 29 carbon atoms that is substituted by acyclic substituents, a cycloaliphatic or cyclo...  
JPH10501526A
PCT No. PCT/EP95/01909 Sec. 371 Date Nov. 27, 1996 Sec. 102(e) Date Nov. 27, 1996 PCT Filed May 19, 1995 PCT Pub. No. WO95/32974 PCT Pub. Date Dec. 7, 1995The utility of known and novel staurosporin derivatives of formula I (I) wherein R...  
JP2705921B2
To obtain the subject derivative useful as a high degree sweetener, etc., by subjecting a sucrose alkyl 4,6-orthoacylate to mild aqueous acidic hydrolysis to provide a mixture of 4- and 6-monoesters of sucrose and then treating the ester...  
JPH10500394A
Staurosporin derivatives of formula (I), wherein R1 is formyl, an aliphatic hydrocarbon radical having up to 29 carbon atoms that is unsubstituted or substituted by aryl, or is an aryl radical, R2 is an aliphatic, carbocyclic, carbocycli...  
JPH09506071A
A method for protecting against mutational damage in mammalian cells induced by irradiation comprising administering a phosphorothioate or phosphorothiate metabolite selected from the group consisting S-2-(3-aminopropylamino)ethylphospho...  
JP2614407B2
Pharmaceutically acceptable compositions of matter comprising a lipophilic oligosaccharide antibiotic, e.g., the everninomicin-type antibiotic of Formula III, at least a stoichiometric amount of a base, e.g., NMG, an amount of, e.g., hyd...  
JPH09132585A
To provide a new amino sugar suitable for the production of chitooligosaccharides and analogous oligosaccharides usable for pharmaceuticals, drug-delivery system materials, porous beads, surfactant, etc., by, e.g. the addition reaction i...  
JP2607897B2  
JP2607896B2  
JP2597618B2  
JP2582383B2  
JP2580538B2
PURPOSE: To selectively acetalize the specific sites of a saccharide in a good yield by reacting the saccharide with a bulky organic group-having thiocarbonyl compound in the presence of a base and a silver salt or a copper salt, while i...  
JP2569012B2
The invention concerns the esters of hyaluronic acid in which all or only a portion of the carboxylic groups of the acid are esterified, and the salts of the partial esters with metals or with pharmacologically acceptable organic bases.T...  
JPH093088A
PURPOSE: To obtain a new aminodisaccharide comprising specific aminodisaccharides having oxazoline ring structure, capable of providing chitin or analogue polysaccharides by polyaddition reaction due to the action of chitinase and useful...  
JPH093087A
To obtain a trehalose derivative excellent in surface-active ability and safety to skin and useful as a surfactant, etc., capable of using for cosmetics, medicines, foods, etc., by reacting trehalose with an acetal compound in the presen...  
JPH08325167A
To obtain a reagent having an alkoxyl group having an unsaturated group at the β-position, e.g. propargyl, benzyl or allyl group and useful for cleaving an unsaturated alkoyloxycarbonyl functional group. (A) A reagent comprising (I) an ...  
JP2558051B2
PURPOSE: To provide the subject reagent having excellent selectivity and useful for peptide synthesis or the like comprising an aqueous phase, a specific catalyst and a nucelophilic compound soluble in water, which cleaves unsaturated al...  
JPH08245612A
To prepare a specific hexene derivative useful for obtaining an intermediate for an antiviral agent in an excess of the erythro isomer by reacting an organometallic complex of a specified propene derivative with D- glyceraldehyde pentani...  
JP2528332B2  
JPH08208681A
To obtain the subject derivative useful as a high degree sweetener, etc., by subjecting a sucrose alkyl 4,6-orthoacylate to mild aqueous acidic hydrolysis to provide a mixture of 4- and 6-monoesters of sucrose and then treating the ester...  
JP2515261B2  
JPH08506321A
Compounds of this invention are derivatives of pentose monosaccharides which exhibit anti-proliferative and anti-inflammatory activity as well as intermediates for the synthesis of these compounds. Methods of preparation, pharmaceutical ...  
JP2512400B2  
JP2512401B2  
JP2509189B2  
JP2505817B2
Sucrose 6-acylates, key intermediates in the preparation of sucralose, can be prepared by subjecting a sucrose alkyl 4,6-orthoacylate to mild aqueous acidic hydrolysis to provide a mixture of sucrose 4- and 6-acylates and then treating t...  
JPH08127588A
PURPOSE: To stereoselectively and efficiently obtain galactofuranosides which exist in sugar chain part of an enzyme and cell wall lipopolysaccharide of bacteria by reacting a specific thioglycoside derivative with an alcohol derivative ...  
JPH08119985A
PURPOSE: To provide a method for producing a sugar acetonide without using an inorganic acid, phosphorus pentoxide, iodine or a solid catalyst and without requiring the removal of water with an azeotropic mixture. CONSTITUTION: This meth...  
JPH08104651A
PURPOSE: To provide a drug-delivery material composed of a polymer having a reduced-type sugar on the side chain and useful as an agent for promoting the absorption of drug through the mucosa of digestive system including the oral cavity...  
JPH0830075B2  
JPH0873484A
To obtain the subject new compound comprising a specific saccharic compound having a tetrahydropyran structure, having a vascularization-inhibiting ability and low toxicity and useful for treating diabetic retinopathy, chronic rheumatoid...  
JPH0873485A
PURPOSE: To obtain the subject compound, useful for a raw material, etc., for liquid crystals, medicines, agrochemicals, etc., by optically resolving a recemic 1-benzyloxy-6,6,6-trifluoro-4-hexyn-3-ol, then carrying out the reduction of ...  
JPH0853485A
PURPOSE: To selectively acetalize the specific sites of a saccharide in a good yield by reacting the saccharide with a bulky organic group-having thiocarbonyl compound in the presence of a base and a silver salt or a copper salt, while i...  
JPH0816116B2  
JPH0848688A
PURPOSE: To remove an allyl group, etc., in high selectivity and high yield without exercising bad influence on other functional group by reacting a specific compound containing an allyl group, etc., with a sulfinic acid compound in the ...  
JPH08500112A
This invention describes both known and novel compounds, some of which are protein kinase inhibitors, that may be combined with taxol type compounds. The combination of disclosed compounds plus taxol type compounds exhibits powerful syne...  
JPH07324060A
PURPOSE: To carry out a position-selective cis-aminohydroxylation reaction different from conventional reactions to obtain the compound in which an N- substituted amino group is introduced to the sterically crowded side. CONSTITUTION: Th...  
JPH07316178A
PURPOSE: To obtain new compounds having excellent saccharide hydroxidase- inhibiting activity and useful as antibestics, antidiabetics, insecticides and anti- HIV agents. CONSTITUTION: A compound of formula I (R1 is H or a saccharide res...  
JPH07316179A
PURPOSE: To obtain a new compound having excellent radiation damage- protecting action. CONSTITUTION: A compound of the formula (R1 is an amino which may be substituted with a 1-6C alkyl, etc.; R2 is H or a 1-6C alkyl; R3 is a 1-6C alkyl...  
JPH07309885A
PURPOSE: To obtain a dinucleoside analogue useful for treatment of virus diseases such as influenza, herpes and HIV and a mononucleoside analogue used for intermediates or the like for production of an oligonucleoside. CONSTITUTION: This...  
JPH07304783A
PURPOSE: To obtain a novel phosphinate ester that is useful as a starting material for producing an antiviral agent and can eliminate the protecting group under mild basic conditions by reacting phosphinic acid with an alcohol or a chlor...  
JPH07291988A
PURPOSE: To obtain new sulfamic acid derivatives which are specific fructopyranose cyclic sulfites or sulfates and have anticonvulsant activity and diuretic activity and useful for treatment or the like of epilepsy, glaucoma, peptic ulce...  
JPH07196679A
PURPOSE: To obtain a new compound capable of producing hydantocidin in high yield without forming stereoisomers. CONSTITUTION: This sugar derivative is a compound of formula I [R1 and R2 each is H or together form a (substituted) alkylid...  
JPH0762024B2  
JPH07504421A
Compounds are described of formula (I), wherein R<1> represents a hydroxyl group or a group selected from -OCOCH=CHCH(CH3)(CH2)3CH3, -OCOCH=CHC(CH3)=CHCH(CH3)CH2CH3 or -OCO-X-CH2CH(CH3)CH2CH3[where X is -CH=CHCH(CH3)-, -CH2CH(OH)CH(CH3)-...  

Matches 501 - 550 out of 864