Document |
Document Title |
JPS6247878B2 |
Novel steroids of the formula I wherein R1 is linear or branched alkyl of 1 to 12 carbon atoms, unsaturated alkyl of 2 to 8 carbon atoms optionally substituted, optionally substituted aryl of 6 to 12 carbon atoms, optionally substituted ...
|
JPS6247879B2 |
|
JPS6239160B2 |
Novel 7-alkyl- DELTA 4-17 alpha -pregnene-3-ones of the formula I wherein R is selected from the group consisting of saturated and unsaturated alkyl of 2 to 8 carbon atoms, cycloalkyl alkyl of 4 to 8 carbon atoms and arylalkyl of 7 to 12...
|
JPS6238360B2 |
The present invention relates to a new series of fusidic acid derivatives, to salts and easily hydrolysable esters thereof, to the preparation of these compounds, and to pharmaceutical compositions containing the compounds, the new fusid...
|
JPS6234040B2 |
Corticoid-21-sulphopropionate derivs. of formula (I) and their salts with pharmaceutically-acceptable bases are new: (St = steroid residue of an antiinflammatory corticoid; esp. it has formula (X = H, Cl, F or CH3; Y = H, F or Cl; Z = ox...
|
JPS6221800B2 |
|
JPS6220198B2 |
Novel cyclization substrates are disclosed of the formula (III) wherein: (a) R1 is H or alkyl of one to four carbon atoms; (b) R2 is H or alkyl of one to four carbon atoms, with the proviso that R1 is H when R2 is alkyl, and with the pro...
|
JPS6220196B2 |
Novel DELTA 1,3,5(10),6-estratetraenes of the formula I R is selected from the group consisting of hydrogen, acyl of an alkanoic acid of 1 to 5 carbon atoms, optionally substituted benzoyl, tetrahydropyranyl, trityl and trimethylsilyl an...
|
JPS6212799B2 |
Disclosed is a process for the preparation of a 4,6-dien-3-one steroid by brominating an enolic ether of a 4-en-3-one steroid in a water-containing organic solvent which is substantially free from acetic acid and sodium acetate to give a...
|
JPS629119B2 |
|
JPS61503032A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
|
JPS6160080B2 |
|
JPS61225190A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
|
JPS61502186A |
Novel compounds having the general formula (I), wherein: R<1> is hydrogen or an acyl substitutent of formula -(C=O)-R<2>, wherein: R<2> is an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkylene, haloalkyl, aryl, haloaryl or arylalkyl...
|
JPS6128100B2 |
A method and reagent means for the determination of small quantities of chemical compounds in man, animal and plants by a specific binding assay technique. The method involves the utilization of a labelling constituent comprising a conju...
|
JPS61115095A |
Steroid-21-phosphoric acids and pharmaceutically usable salts thereof of the formula III III (in which U=H or CH3, V=H, OH, O or Hal; W=H or OH and Y=H or F) are obtained in a very pure state by reacting I I (in which X=OH or Hal) with a...
|
JPS6119640B2 |
DELTA 15-Steroids of the formula wherein R1 is a hydrogen atom, trialkylsilyl or acyl; R2 is ethynyl, chloroethynyl or propinyl; and X is an oxygen atom, or NOR4 wherein R3 is a hydrogen atom or acyl and R4 is a hydrogen atom, acyl, alky...
|
JPS6113720B2 |
Novel compounds having the formula (II) where X is radioactive Se or Te, z is 0 or 1 and R is OH or an amino acid residue, particularly 23-[75Se]-selena-25-homocholic acid and its glycine and taurine conjugate have outstandingly good pro...
|
JPS6172798A |
A process for preparing a 17 alpha -hydroxy-20-keto steroid comprises contacting a DELTA <1><6>-20-keto steroid with a silylating agent in the presence of a catalyst, and contacting the resultant DELTA <17(20)>-20-silyl ether steroid (so...
|
JPS617437B2 |
A mixture of ursodeoxycholic acid and of chenodeoxycholic acid as well as of their salts and esters is reacted with a silylating agent in a suitable anhydrous organic solvent; the corresponding silyl-derivatives thus obtained are separat...
|
JPS6140298A |
PURPOSE: To provide the titled complex having increased rate of dissolution in water and absorbability through digestive tracts, and having antiarteriosclerotic and gonadotropic activities, etc., by clathrating a cycloartenol ferulic aci...
|
JPS617294A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
|
JPS611080B2 |
1368005 7-Carboxy steroids and related compounds G D SEARLE & CO 24 Aug 1972 [25 Aug 1971] 39401/72 Heading C2U Novel steroids have the formulµ wherein Z is H, alkali metal, alkaline earth metal/2, ammonium or alkyl; Z1 is H, alkali met...
|
JPS617292A |
PURPOSE: To obtain the titled compound having strong carcinostatic activity, by reacting the bonding an estracyt compound with a carcinostatic agent having a specific functional group. CONSTITUTION: An estracyt compound [preferably estra...
|
JPS615094A |
Novel, multiple-tritiated steroid-20,17- spirolactones of general Formula 1 wherein -A-B is -CH2-CH2-, -CH=CH- or and R is hydrogen or tritium and n is 0 or 1, are usable as tracer materials for the detection of mineralocorticoid receptors.
|
JPS611699A |
C16-unsaturated corticoids are readily transformed to the corresponding 16 alpha -methyl-17 alpha -hydroxy corticoids by use of a DELTA 17(20)-20-silyl ether.
|
JPS60502152A |
The invention provides a new derivative of vitamin D, 23,23-difluoro-25-hydroxycholecalciferol, a method for preparing said compound and various new intermediates utilized in such process. The compound is characterized by vitamin D-like ...
|
JPS60226894A |
2-Fluoro-17β-estradiol is synthesized by mercurating at C-2 a 17β-estradiol diester or dietherate, displacing the mercury group with fluorine and then removing the ester- or ether-protecting groups.
|
JPS6050199B2 |
The invention relates to novel spirooxazolidines represented by the formula I (I) wherein R1 is alkyl having from 1 to 4 carbon atoms; R2 is hydrogen, alkyl having from 1 to 4 carbon atoms, alkenyl having from 1 to 4 carbon atoms, or dia...
|
JPS60222496A |
NEW MATERIAL:A compound shown by the formula I (X is hydroxy, Y is alkali metallic salt of carboxyethyl, or X and Y together with neighboring carbon atom form lactone ring shown by the formula II). EXAMPLE: 17-Hydroxy-6β-,7β-methylene-...
|
JPS60174798A |
Antiinflammatory activity is exhibited by pregnenes having the structural formula wherein R1 is hydrogen, hydroxy, halogen, or acyloxy; R2 and R3 are each hydrogen, R2 and R3 are each methyl, R2 and R3 are each alkylthio, R2 is hydrogen ...
|
JPS6069096A |
Steroids of the formulaand a therapeutic composition containing same which are useful as anti-cancer, anti-obesity, anti-hyperglycemic, anti-autoimmune and anti-hypercholesterolemic agents.
|
JPS6061595A |
Steroids of the formula I wherein n represents the number 2, 3 or 4; R1 represents hydrogen, lower-alkyl or lower-alkylidene; R2, R3 and R4 represent hydrogen or lower-alkyl and the dotted C-C bonds in the 5(6)-, 7(8)-, 22(23)-, 24(28)- ...
|
JPS6034990A |
17-haloethynyl steroids of the partial formula wherein R1 is hydrogen or methyl, R2 is alkyl of 1-4 carbon atoms, acyl of 1-7 carbon atoms, trimethylsilyl, 2-tetrahydropyranyl, or nitrate, X is bromine or iodine, and V is methylene, ethy...
|
JPS6017445A |
Photosensitive bodies that are sensitive to ultraviolet radiation and that exhibit excellent contrast are formed from base soluble polymers such as poly(methyl methacrylate-co-methacrylic acid) physically mixed with base insoluble materi...
|
JPS59208547A |
Photosensitive bodies that are sensitive to ultraviolet radiation and that exhibit excellent contrast are formed from base soluble polymers such as poly(methyl methacrylate-co-methacrylic acid) physically mixed with base insoluble materi...
|
JPS5940840B2 |
The present invention relates to a dienic derivative of the androstane series having the formula WHEREIN R is a member selected from the group consisting of hydrogen, alkyl having 1 to 4 carbon atoms and alkali metal, R' and R'' are memb...
|
JPS59139400A |
NEW MATERIAL:A compound of formula I (X is H, halogen, hydroxyl; Y is H, lower alkyl, halogen, alkylthio; X and Y may incorporate to form a ring; Z1 is hydroxyl; Z2 is carboxyethyl alkali metal salt; Z1 and Z2 may incorporate together wi...
|
JPS5980695A |
The present invention relates to an estrogen complex which consists of an estrogen or an estrogen derivative complexed with an organometallic compound containing at least one free carbonyl ligand, the said estrogen complex containing at ...
|
JPS5973600A |
PURPOSE: An ovulatory inducing agent, containing 24-methylenecycloartanol as a main constituent, and useful as a remedy for amenorrhea, dysmenorrhea, ovulatory disorder, menstrual cycle abnormality, etc. CONSTITUTION: An ovulatory induci...
|
JPS5967300A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
|
JPS5850238B2 |
|
JPS5850240B2 |
The present invention relates to a dienic derivative of the androstane series having the formula WHEREIN R is a member selected from the group consisting of hydrogen, alkyl having 1 to 4 carbon atoms and alkali metal, R' and R'' are memb...
|
JPS5848526B2 |
6,9-Oxido-9,10-seco-1,3,5(10),6,8,14-estrahexaenes, useful as intermediates in the total synthesis of steroids, of the formula WHEREIN N IS 1 OR 2, R1 is lower-alkyl, R2, R 3 and R4 are H, alkoxy or acyloxy, X is a free or ketalized keto...
|
JPS5842879B2 |
An alkali metal salt of a 3-(17 beta -hydroxyandrosten-3-one 3-acetal-17 alpha -yl)propiolic acid which is useful as an intermediate in the preparation of 3-(3-oxo-7 alpha -acetylthio-17 beta -hydroxyandrost-4-en-17 alpha -yl)-propiolact...
|
JPS58150600A |
PURPOSE: To prepare a uniform solution or a solid substance, by dissolving a ferulic acid ester of 24 methylenecycloartanol useful as an antioxidant for products of fats and oils in a fatty acid ester, etc. under heating, adding an edibl...
|
JPS5839840B2 |
1368005 7-Carboxy steroids and related compounds G D SEARLE & CO 24 Aug 1972 [25 Aug 1971] 39401/72 Heading C2U Novel steroids have the formulµ wherein Z is H, alkali metal, alkaline earth metal/2, ammonium or alkyl; Z1 is H, alkali met...
|
JPS58113200A |
New steroidal chiral phosphines of formula (I) wherein R represents a phosphorated group selected between methods for their preparation; catalytic systems comprising metal complexes and the above steroidal chiral phosphines; asymmetrical...
|
JPS5822479B2 |
Novel 1 alpha ,3 beta -dihydroxy-24-oxocholesta-5,7-diene and the hydroxyl group-protected derivatives thereof. Said novel 1 alpha -hydroxy-24-oxovitamin D3 and said novel intermediates are also useful as the intermediates of 1 alpha ,24...
|
JPS5852268A |
1. Claims for the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A cholecalciferol derivative of the formula see diagramm : EP0073465,P14,F3 1. Claims for the contracting state : AT A process for the manufacture of a choleca...
|