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Patent Searching and Data


Matches 1 - 50 out of 1,126

Document Document Title
WO/2022/149584A1
The present invention provides a peptide having a fluoroalkyl group as a side chain. The present invention pertains to a peptide in which two or more amino acids are peptide-bonded, wherein at least one of the amino acid residues constit...  
WO/2022/109163A1
Controlled release biodegrading microcapsules comprising polypeptide chains.  
WO/2022/097500A1
A protein or peptide crosslinking agent which is represented by formula (I). [In the formula, A is a hydrogen atom, a C1-6 alkyl group which may be substituted with a phenyl group or a halogen atom, or a phenyl group.]  
WO/2022/065173A1
Provided are: a membrane-permeable molecule which has a structure represented by general formula (i) and forms a salt with an acid having a pKa value greater than -8.0 and less than 4.7; and a method for improving the membrane permeabili...  
WO/2022/065172A1
A cell membrane-permeable molecule which has a structure represented by general formula (I) and which is in the form of a salt with an acid having a pKa value of lower than 4.7; and a method of improving the cell membrane permeability of...  
WO/2022/054625A1
Provided is a complex containing a pyrrole-imidazole polyamide that recognizes a particular DNA sequence and binds thereto and containing peptide that contains 1-5 arginine residues.  
WO/2021/235494A1
Provided is a medical agent that exerts preventative and therapeutic effects against viral infections, by inhibiting proteases of viral origin on the basis of the effects of various physiological activities of an active sulfur compound p...  
WO/2021/231920A1
The present disclosure relates to methods of writing data in nucleic acid chains and methods of reading data written in nucleic acid chains. The present disclosure also relates to a kit for writing and reading data in nucleic acid chains.  
WO/2021/156331A2
The invention relates to use of ionic polymers (IP) consisting of anions and a polymeric backbone containing cations, in hydrolyzing proteins and protein-containing feedstock to produce protein hydrolysates.  
WO/2021/155354A1
A method for the prevention, treatment, or amelioration of a medical disease or condition associated with inflammation caused by glutamate excitotoxicity comprising administering to a patient a peptide that binds to or interferes with th...  
WO/2021/136475A1
A linker molecule for targeting molecule-drug conjugate, has the structure of formula (I): A1p-D1q-Y-Lk-W-A2q-D2p (I). A conjugate has the structure of formula (III): A-((compound of formula (I))-PL t) z (III). The conjugate can be used ...  
WO/2021/108919A1
A method and system for generating a protein sequence is implemented using a computer-implemented neural network. An empty or partially filed sequence of node elements, representing amino acid positions of the protein sequence, and an ed...  
WO/2021/106706A1
The present invention improves the accuracy of searching for an amino acid sequence of interest. An information processing device (amino acid sequence searching device) 1 is provided with: a storage unit 17 that stores a trained model fo...  
WO/2021/058660A1
The present invention is directed to an anti-adsorption solution for the analysis of peptides. Also a process for the preparation of such an anti-adsorption solution and the use of said anti-adsorption solution are described.  
WO/2021/055696A1
Single-module nonribosomal peptide synthetases (NRPSs) and NRPS-like enzymes activate and transform carboxylic acids in both primary and secondary metabolism; and are of great interest due to their biocatalytic potentials. The single-mod...  
WO/2021/047648A1
Provided is a peptide compound comprising the amino acid sequence: G-W-Lys-X1-Ser-U-X2-Y-Z-Q wherein: G represents an optional N-terminal a 3, 4-dihydrocinnamic acid group; W represents Ala or Ser, or is absent; U represents Tyr, DOPA or...  
WO/2021/010316A1
The present invention addresses the problem of providing an N-substituted amino acid-containing peptide and a method for producing a protein binding factor using the peptide. More specifically, the present invention pertains to a peptide...  
WO/2020/262555A1
A side effect reducing agent for a nucleic acid drug that comprises an oligopeptide containing an oligopeptide domain, said oligopeptide domain consisting of 2-40 amino acids and including a structure W that has two or more specific cons...  
WO/2020/226438A1
The present invention relates to a peptide for preventing or treating inflammatory bowel diseases. The peptide of the present invention exhibits excellent effects in preventing or treating inflammatory bowel diseases and thus can be extr...  
WO/2020/213568A1
Disclosed is a method for producing a polymerized polypeptide aggregate, said method comprising a step for reacting a polypeptide, which has a tag on the N-terminal side and/or C-terminal side, with a polymerase to give a reaction liquid...  
WO/2020/203626A1
The present invention provides a biologically-related substance to which a branched degradable polyethylene glycol derivative being decomposed in cells and being represented by formula (A) below is bound. (In the formula, each symbol is ...  
WO/2020/195302A1
Provided is a linker molecule for producing a cell membrane-permeable ring-shaped peptide, the linker molecule having a cell membrane permeability-imparting group; and a ring-forming group which forms a peptide into a ring shape.  
WO/2020/198644A1
The present disclosure is directed to physical mixtures of diblock copolypeptide hydrogel (DCH) systems. These systems exhibit mechanical strength and stiffness that are synergistically increased over the individual component DCHs, to gr...  
WO/2020/158687A1
In the present invention, a method for producing a compound of formula I comprises a step for causing a compound of formula III to undergo a Pechmann condensation reaction with respect to a compound of formula II in the presence of an or...  
WO/2020/125307A1
Disclosed is a method for constructing a Pseudomonas aeruginosa O11 serotype O antigen oligosaccharide using a D-glucose block, a L-fucosamine block and a D-fucosamine block, wherein the D-glucose block or the L-fucosamine block is conne...  
WO/2020/112647A1
This document relates to using bidirectional, multi-enzymatic scaffolds to biosynthesize cannabinoids in recombinant hosts.  
WO/2020/097188A1
Disclosed herein are compositions and methods for the identification of molecules capable of repressing NK-mediated killing of a target (donor) cell. The invention comprises the development and use of an assay to detect the effects of ta...  
WO/2020/077136A1
Charged polypeptides, their conjugates, and fusion proteins comprising such polypeptides are disclosed. Inclusion of such a polypeptide in a fusion protein increases the protein's properties such as stability and circulation half-life, w...  
WO/2020/058889A1
The present patent application relates to the use of an innovative amino acid derivative of glucosamine having the Formula 1 of the general structure which follows, or of a pharmaceutical composition which contains it as a single active ...  
WO/2020/052677A1
There is provided a peptide-containing compound that comprises a peptide component which is an amino acid sequence of from 2 to 45 amino acids, which peptide component is covalently bonded to one or more compounds of the formula (I), whe...  
WO/2020/051566A1
Although numerous investigations are focused on developing vaccines that induce protective humoral responses, fewer studies are aimed at developing vaccines that induce broad and robust T cell responses. In order to design a potent T cel...  
WO/2020/039984A1
The present invention addresses the problem of providing a compound library which has a higher percentage of biologically active compounds. This problem is solved by a compound library that includes cyclic peptides that comprise (i) an a...  
WO/2020/028744A1
Disclosed herein are chimeric receptors and precursors, chimeric antigen receptors and precursors, universal chimeric receptor cell precursors, chimeric antigen receptor T cells, and methods of constructing and using the same.  
WO/2020/004810A1
The present invention relates to a method for preparing a poly-γ-glutamic acid hydrogel by using ultraviolet rays, and a use of a poly-γ-glutamic acid hydrogel prepared by the preparation method. The method for preparing a poly-γ-glut...  
WO/2019/246392A1
The present disclosure provides a cytokine-based bioactivatable drug construct ("VitoKine") platform that aims to reduce systemic mechanism-based toxicities and lead to broader therapeutic utility for proteins and cytokines such as IL-15...  
WO/2019/240288A1
The present invention provides art that enables modification of an antibody, particularly regioselective modification of an antibody. More specifically, the present invention provides a substance having affinity for an antibody, and a co...  
WO/2019/199733A1
Provided herein are compositions and methods for treating cancer. In particular, provided herein are compositions, methods, and uses of inhibitors of ARlnc1 for treating cancer.  
WO/2019/195859A1
The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for trea...  
WO/2019/176860A1
This cell adhesive material is obtained by modifying a substrate surface by using a peptide group comprising a peptide that contains: 40% to 75%, inclusive, of one or more types of basic amino acid residues selected from the group consis...  
WO/2019/135233A1
Disclosed herein is a process of preparing a polypeptide copolymer by polymerizing a mixture comprising N-carboxyanhydrides of alanine, tyrosine, carboxylate-protected glutamate and an amine-protected lysine, to form a protected polypept...  
WO/2019/117274A1
With regard to the present invention, it was discovered that a deprotection agent can be deactivated by a salt formed from a base and an acid having characteristics (i) and (ii), and as a result, excessive elongation of a peptide can be ...  
WO/2019/114159A1
A Camellia Oleifera meal polypeptide as well as a preparation method and an application thereof. The Camellia Oleifera meal polypeptide is prepared by taking Camellia Meiocarpa Hu. meal as raw materials, hydrolyzing the Camellia Meiocarp...  
WO/2019/110774A1
The invention relates to a composition in the form of an injectable aqueous solution having a pH of between 6.0 and 8.0 and comprising at least: a basal insulin having an isoelectric point (pI) of between 5.8 and 8.5; b) and a co-polyami...  
WO/2019/110797A1
The invention relates to a composition in the form of an injectable aqueous solution having a pH of between 6.0 and 8.0 and comprising at least: • a) amylin, an amylin receptor agonist or an amylin analog; • b) a co-polyamino acid be...  
WO/2019/102469A1
Anti-fogging proteinoid compounds are disclosed. Processes of preparing antifogging proteinoid compositions and incorporating thereof in or on a substrate are disclosed. Articles of manufacturing incorporating such compositions are also ...  
WO/2019/088167A1
Provided is a purification agent which comprises a compound having a betaine structure, and which is for a sugar chain having a length equal to or longer than that of a monosaccharide or for a glycopeptide having a sugar chain having a l...  
WO/2019/046699A1
The invention includes a bioelectronic interface comprising a self-assembling unit, wherein the self-assembling unit comprises a variant GPCR fusion protein bound to an S-layer fusion protein. The invention also encompasses a biosensor o...  
WO/2019/031446A1
[Problem] To provide a method and a composition for enhancing the immunogenicity of a polypeptide. [Solution] Provided is a composition containing a tagged polypeptide which is composed of a polypeptide, a spacer peptide bonded to a term...  
WO/2019/018238A1
In certain embodiments osteoadsorptive fluorogenic substrates of cathepsin K (or other proteases) are provided. Utilizing a bisphosphonate targeting moiety, the fluorogenic substrates provide effective bone-targeted protease sensor(s). I...  
WO/2018/225864A1
The present inventors found that, in screening a cyclic peptide compound capable of specifically binding to a target molecule, the hitting rate of a cyclic peptide compound capable of specifically binding to the target molecule can be im...  

Matches 1 - 50 out of 1,126