Peptides

Matches 401 - 450 out of 838	< 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 >

Document	Document Title
WO/1988/009670A1	PREVENTION AND TREATMENT OF RETROVIRAL DISEASE The present invention provides a non-infectious immunogen containing retroviral particles devoid of outer envelope proteins or containing selected antigens isolated from a retrovirus. There is also provided a vaccine effective against HI...
WO/1988/007548A1	LEUKAEMIA-INHIBITORY FACTOR A leukaemia-inhibitory factor (LIF) is disclosed, together with a method of preparation of LIF in essentially pure form. Nucleotide and amino acid sequences are disclosed, together with recombinant DNA molecules and host cells for produc...
WO/1988/000835A1	PRODUCTION AND USE OF ANTHELMINTIC AGENTS AND PROTECTIVE ANTIGENS The protein doublet H110D, the individual components thereof, and the production and use thereof in a vaccine against a nematode infection. This protein doublet is a plasma membrane-associated protein material of the intestinal microvill...
WO/1987/003785A1	A PROCESS FOR THE PREPARATION OF A HEAT RESISTANT NON-BITTER WATER-SOLUBLE PEPTIDE PRODUCT, THE PRODUCT PRODUCED BY THE PROCESS, AND NUTRIENTS, REFRESHMENTS AND DIETETICS COMPRISING THE PRODUCT A non-bitter, heat resistant easily water-soluble peptide product is produced from whey protein materials by eliminating therefrom casein and by enzymatically hydrolyzing the casein-free whey proteins and separating the hydrolyzate by ul...
WO/1987/003786A1	A PEPTIDE PREPARATION, A PROCESS FOR PRODUCING IT AND USE OF THE PEPTIDE PREPARATION A peptide preparation from hydrolysis of whey containing peptides with a molecular weight of up to 6,000 Dalton. Such a preparation is hypoallergenic and therefore useful in food products and stimulants, such as mother's milk substitutes...
JP2024515306A	Bicyclic peptide ligand specific for P-selectin Bicyclic peptide ligand specific for P-selectin The present invention relates to polypeptides that are covalently attached to a molecular scaffold such that two or more peptide loops reside between the points of attachment to the molecul...
JP2024514648A	Cell-penetrating peptides, anticancer peptides, and pharmaceutical compositions for preventing or treating cancer containing the same The present invention relates to a cell-penetrating peptide, an anti-cancer peptide, and a pharmaceutical composition for preventing or treating cancer containing the same. Since the cancer therapeutic peptide can further improve the can...
JP2024043291A	liquid formulation [Problem] Realization of pharmaceuticals with polysulfide bonds. The present invention provides a liquid preparation containing a compound represented by formula (III), or a pharmaceutically acceptable salt or solvate thereof, and at lea...
JP2024513391A	Conjugated hepcidin mimetics The present invention provides hepcidin analogs with improved in vivo half-lives, and related pharmaceutical compositions and methods of use thereof.
JP2024513392A	Conjugated hepcidin mimetics The present invention provides hepcidin analogs with improved in vivo half-lives, and related pharmaceutical compositions and methods of use thereof.
JP7453725B2	Heterologous peptide production based on fluorescence fusion The present invention relates to a method of producing a heterologous polypeptide of interest in a host cell, wherein the method comprises expressing a fusion protein comprising the heterologous polypeptide of interest and a fluorescent ...
JP2024038168A	Bioactive molecule conjugates, their preparation and uses Bioactive molecule conjugates, methods of preparation, and uses thereof are provided. The present disclosure provides novel bioactive molecule conjugates obtained by improving the coupling of drugs and targeting moieties in antibody-drug...
JP2024511660A	Ezrin peptide 1 for use in methods of treating post-COVID-19 The present invention relates to ezrin peptide 1 for use in methods of treating post-COVID-19 syndrome.
JP2024511369A	Novel peptide conjugates A conjugate formed between an anesthetic compound and a peptide component having the following amino acid sequence: W-Lys-X1-Ser-UX2-Y During the ceremony, W,X1,U,X2, and Y are as defined herein, as well as regioisomers, stereoisomers, a...
JP2024034975A	Probe complex, detection agent for specific microorganisms, method for detecting specific microorganisms, use of the probe complex, use of the first probe or second probe contained in the probe complex, and method for isolating specific microorganisms An object of the present invention is to provide a new probe complex that detects the presence or absence of any base sequence present in living microorganisms. (i) A first probe includes a peptide nucleic acid and a labeling substance, ...
JP2024510577A	treatment The present invention relates to the treatment of cancer in a patient with an αvβ3- and/or αvβ5-integrin targeting agent in combination with at least one immunotherapeutic agent and/or at least one chemotherapeutic agent.
JP2024028776A	Plant peptides and their uses (II) [Problem] To provide a new cosmetic ingredient based on plant origin that meets a specific need in the market and makes human skin and hair healthier, brighter, softer, more moisturized and especially protects keratin fibers from damage ...
JP2024509361A	Crystallization of β-lactoglobulin using multiple protein feeds The present invention relates to an improved method of producing BLG compositions by crystallization of β-lactoglobulin (BLG). The invention utilizes at least two different BLG-containing protein feeds that are mixed to form a supersatu...
JP2024019600A	Selective protein degradation [Problem] To provide selective degradation of proteins. The present invention provides methods for identifying peptides and small molecule moieties that can functionally promote interaction between a target protein and an E3 ubiquitin li...
JP2024501316A	Antibodies specific for structurally disordered sequences The present invention produces specific binding moieties for naturally denatured proteins (IDPs) and/or domains of naturally denatured proteins that tend to be immunologically inert and lack immunogenicity in animals, particularly mammal...
JP2023551122A	Compounds and their use in the treatment of tachykinin receptor-mediated disorders The present invention relates to compounds and their use in the treatment of disorders mediated by tachykinin receptors, such as tachykinin receptor 2. [Selection diagram] None
JP2023551318A	Novel angiotensin I-converting enzyme (ACE) inhibitory peptide The present disclosure provides methods for producing fish-derived peptides with ACE inhibitory activity and peptide isolates comprising fish-derived peptides by hydrolysis of fish meat using the alkaline protease subtilisin. The present...
JP2023550576A	Inhibitors of α-synuclein aggregation and their use The present invention relates to an inhibitor of α-synuclein aggregation characterized by comprising an amphipathic α-helical peptide. The invention further relates to therapeutic and diagnostic uses of such inhibitors and correspondin...
JP2023549476A	Transcriptional activation complex targeting cancer drugs derived from viral protein sequences The present invention provides compositions and methods for treating diseases involving inappropriate or excessive cell proliferation, or inflammatory conditions or autoimmunity, by inhibiting MYC activity in cells such as MYC-dependent ...
JP2023165986A	PEPTIDES AND NANOPARTICLES FOR INTRACELLULAR DELIVERY OF GENOME-EDITING MOLECULES To provide peptides and nanoparticles for intracellular delivery of genome-editing molecules.The present application provides complexes and nanoparticles comprising cell- penetrating peptide that are useful for stabilizing and/or deliver...
JP7378750B2	Cryoprotective composition containing DNA nanostructures and methods for using the same The present invention relates to a composition for cryopreservation, comprising: a nucleic acid structure which comprises a scaffold nucleic acid folded at predetermined positions to form multiple strands, and a plurality of staple nucle...
JP2023547405A	Minimum length shuttle agent peptides and variants thereof adapted for transduction of Cas9-RNP and other nuclear protein cargoes Described herein are compositions and methods for delivering nuclear protein cargoes, such as Cas9-RNP genome editing and ABE-Cas9-RNP base editing complexes, to the cytoplasmic/nuclear compartment of eukaryotic cells by synthetic peptid...
JP2023543444A	Compounds for the prevention or treatment of myasthenia gravis The present invention provides compounds for the sequestration of anti-human muscle type nicotinic acetylcholine receptors (AChR) involved in the pathogenesis of MG. The compound comprises an inert biopolymer scaffold and at least two pe...
JP2023542998A	Amidated peptides presented by non-HLA-A*02 and their deamidated counterparts for use in immunotherapy against various types of cancer The present invention comprises (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) variant sequences thereof that maintain the ability to bind to MHC molecules and/or induce T cells that cross-react with said variant peptide. or a pharmaceutic...
JP2023542997A	Amidated peptides presented by HLA-A*02 and their deamidated counterparts for use in immunotherapy against various types of cancer The present invention is based on (i) SEQ ID NO: 1 to SEQ ID NO: 102, and (ii) variant sequences thereof that maintain the ability to bind to MHC molecules and/or induce T cells that cross-react with the variant peptide. or a pharmaceuti...
JP2023139063A	PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY To provide compositions for alleviating radiation-induced side effects of prostate-specific membrane antigen (PSMA) targeting radiolabeled diagnostics and therapeutics and applications therefor.A pharmaceutical composition includes a com...
JP2023134564A	MEDITOPES AND MEDITOPE-BINDING ANTIBODIES AND USES THEREOF To provide: antibodies and meditopes that bind to the antibodies; complexes, compositions and combinations containing the meditopes and the antibodies; and methods of producing, using, testing and screening the same, including therapeuti...
JP2023538807A	Inhibitors of complement factor C3 and their medical uses Compstatin analogues with improved physicochemical properties compared to the 13 amino acid compstatin peptide, such as increased stability and/or solubility, especially compstatin that additionally has useful binding and complement inhi...
JP2023123755A	METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION To provide a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA.The present disclo...
JP7333857B2	adenoviral vector The present invention provides recombinant adenoviral vectors, immunogenic compositions thereof and their uses in medicine. In particular, the present invention provides an adenoviral vector comprising the genome of an adenovirus other t...
JP2023536497A	immunogenic compounds The antigenic peptide has the structure:X1-X2-X3-X4-X5-X6-X7-PX9-X10-X11-X12and is derived from amino acids 113-124 of α-synuclein. According to the structure: P is proline; X1is L, K, A or S, where L is leucine, K is lysine, A is alani...
JP2023536192A	peptide-based linker The present invention relates to novel linkers comprising two or three basic, acidic or hydrophobic natural or unnatural amino acids. The invention also relates to drug conjugates comprising said linkers, pharmaceutical compositions comp...
JP7320455B2	Hydrophilic linkers and their conjugates Hydrophilic linkers and their conjugates are disclosed. Formula (I) (II)
JP2023533168A	Modulator of tight junction permeability The present invention relates to compounds capable of modulating the permeability of junctions between epithelial cells and their use for enhancing the delivery of substances such as therapeutic and diagnostic agents across epithelial su...
JP7317375B2	PSMA ligand for imaging and internal radiotherapy The invention relates to imaging and endoradiotherapy of diseases involving prostate-specific membrane antigen (PSMA). Provided are compounds which bind or inhibit PSMA and furthermore carry at least one moiety which is amenable to radio...
JP2023532595A	Therapeutic use of calcium-activated chloride channel peptide activators The present disclosure relates to calcium-activated chloride channel peptide activators and therapeutic uses thereof.
JP7309797B2	Meditopes and meditope-binding antibodies and uses thereof Antibodies and meditopes that bind to the antibodies are provided, as well as complexes, compositions and combinations containing the meditopes and antibodies, and methods of producing, using, testing, and screening the same, including t...
JP2023530128A	Conjugates of cell binding molecules and camptothecin analogues The present invention relates to conjugates of camptothecin analogues represented by formula (I) and cell-binding molecules, wherein R1, R2, R3, R4, R5, X, L, n, m, T, and [Chemical 1] is defined herein. Also provided are methods of maki...
JP7305542B2	Exon skipping by peptide nucleic acid derivatives A peptide nucleic acid derivative of Formula I is provided to tightly bind to a splice site within a pre-mRNA in a sequence specific manner. Given with excellent cell membrane permeability and strong affinity for RNA, the said peptide nu...
JP2023529435A	Cyclic peptide inhibitors of PSD-95 and their uses The present invention provides novel cyclic peptides that can act as inhibitors of protein/protein interactions, specifically by inhibiting the PDZ2 domain of PSD-95, as well as excitotoxicity-related peptides. of their use in the treatm...
JP7294012B2	Protein Stabilizer, Reagent Containing Stabilized Protein, and Method for Stabilizing Protein Contained in Reagent To provide a protein stabilizer that can stabilize protein contained in a reagent used in biochemical measurement, a reagent that contains stabilized protein and has good liquid dropping properties, and a method of stabilizing protein co...
JP2023521797A	NOVEL ANTIMICROBIAL PEPTIDES OR PEPTIDE ANALOGUES AND USES THEREOF The present invention relates to novel antimicrobial peptides or peptide analogues and their use in treating bacterial infections, specifically having an alpha helical amphipathic peptide structure composed of hydrophobic and hydrophilic...
JP2023068430A	ANTIBACTERIAL PEPTIDE To provide a new polypeptide having antibacterial activity.Provided is a polypeptide having (a) an amino acid sequence having a specific sequence, (b) an amino acid sequence having an identity of 80% or more with respect to the amino aci...
JP7274223B2	A Universal Vaccine Based on Common Tumor Neoantigens for the Prevention and Treatment of Microsatellite Instability (MSI) Cancers This invention relates to a method of selecting a collection of frame-shift peptides (CFSPs) to produce a universal cancer vaccine peptide collection (CVP) for prophylaxis and treatment of patients with hereditary and sporadic micro-sate...
JP2023518808A	Structured High Protein Meat Substitute Compositions with Microbial Heme Flavor Ingredients Structured food compositions, such as meat substitute compositions, comprising microbial-derived protein products, such as microbial-derived protein hydrolysates, are described. Methods of making such products are also described. Flavor ...

Matches 401 - 450 out of 838	< 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 >