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WO/2024/024720A1 |
Provided are a method, an agent, etc. for enhancing the stability of a medium and enhancing the productivity of a recombinant protein. More specifically, provided are: a medium containing N-acetylcysteine and L-cysteine; a method for cul...
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WO/2024/024989A1 |
This micro-organism growth detection method involves: preparing droplets containing pigment in which the fluorescence intensity changes due to the interaction between micro-organisms and a film component containing the micro-organisms in...
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WO/2024/025094A1 |
The present invention relates to an antibacterial, antifungal, or antiseptic composition comprising a Paenibacillus elgi strain having antibacterial and antifungal activity, a culture medium or extract thereof, and a method for preparing...
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WO/2024/025381A1 |
The present application relates to a novel fermented apple composition and a use thereof.
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WO/2024/025051A1 |
The present application pertains to a fermented apple composition that has the effect of reducing or inhibiting the expression of inflammatory cytokines, and a use thereof for the prevention or alleviation of enteritis.
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WO/2024/024906A1 |
The present invention addresses the problem of providing a feature for promoting utilization of an oligosaccharide having a lacto-N-neotetraose skeleton in Bifidobacterium breve. The present invention provides a composition for promoting...
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WO/2024/023259A1 |
The present invention relates to a compound of formula I, a stereoisomer, a tautomer and/or a dimer thereof or a salt thereof, (I) wherein M is a metal among the group of Mg, Cu and Zn; R1 is a methyl group or a formyl group; R2 is a car...
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WO/2024/026030A1 |
Methods are disclosed for generating aerial mycelium, such as mycological material comprising solely mycelia from depleted substrate or depleted and rejuvenated substrate. Alternatively, methods are disclosed for generating mycelia and m...
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WO/2023/022662A9 |
Disclosed herein are cultures comprising Lactobacillus pobuzihii strains and uses thereof. Also disclosed herein are processes of fermentation, as well as soy sauce products, methods using the bacterial strains disclosed herein.
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WO/2024/024427A1 |
The present disclosure provides a method for determining outer membrane detachment in a cyanobacterium that makes it possible to conveniently determine whether or not the outer membrane of the cyanobacterium has been detached from the ce...
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WO/2024/025050A1 |
The present application relates to: a fermented apple composition having the effect of reducing or inhibiting collagenase expression caused by UV rays; and uses thereof for improving the skin, and preventing or inhibiting skin photoaging.
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WO/2024/025315A1 |
The present invention relates to a recombinant expression vector for VC1 protein secretion, and an attenuated Salmonella strain transformed therewith, and provides: a recombinant expression vector comprising the flgM gene, the VC1 gene, ...
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WO/2024/025312A1 |
The present invention relates to a recombinant expression vector for secretion of IFN-β proteins and an attenuated Salmonella strain transformed by means of same, and provides: a recombinant expression vector comprising flgM genes, IFN-...
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WO/2024/025480A2 |
The present invention relates to the recombinant yeast for porcine interferon-alpha 1 production (recombinant poIFN-α1) comprises yeast host cell, porcine interferon-alpha 1 gene and methanol-inducible protein expression vector comprisi...
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WO/2024/025101A1 |
The present invention pertains to (Saccharomyces cerevisiae) SPC Y76LT (KCTC 14767BP). The yeast strain (SPC Y76LT) of the present invention exhibits excellent fermentation efficiency across various sugar contents and thus can be applied...
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WO/2024/021482A1 |
The present invention belongs to the field of microorganisms. Disclosed is bacillus coagulans capable of stably producing flavor substances of stinky tofu. According to the present invention, a bacillus coagulans strain is obtained from ...
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WO/2024/022474A1 |
Provided is a chimeric transcriptional activator for a methanol-inducible promoter, which at least comprises a first portion and a second portion, wherein: 1) the first portion comprises: i) a DNA binding domain; or ii) a DNA binding dom...
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WO/2024/025296A1 |
The present invention relates to a recombinant expression vector for secretion of chlorotoxin, and an attenuated Salmonella strain transformed by means of same, and provides: a recombinant expression vector comprising the flgM gene and a...
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WO/2024/026153A1 |
Disclosed are methods for producing from a gaseous substrate comprising CO, CO2, and optionally H2 at least one oxygenated product. Also provided are methods of using a broth deficient in thiamine or thiazole-containing thiamine precurso...
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WO/2024/022036A1 |
Akkermansia muciniphila, which comprises one or both among AM06 and AM02. AM06 is Akkermansia muciniphila with an accession number of CGMCC No. 22793, and AM02 is Akkermansia muciniphila with an accession number of CGMCC No. 22794. It ha...
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WO/2024/024806A1 |
This phenolic compound production method is a method for producing a compound represented by formula (2) from a compound represented by formula (1), and comprises a step for bringing an enzyme into contact with the compound represented b...
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WO/2024/026469A1 |
The invention provides a recombinant Yarrowia lipolytica. The recombinant Yarrowia lipolytica comprises a heterologous polynucleotide encoding a fusion protein. The fusion protein comprises a first amino acid sequence and a second amino ...
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WO/2024/026465A1 |
Described in several example embodiments herein are engineered programmable pattern recognition compositions and uses thereof. In certain example embodiments, the engineered protein contains an NTPase of a Signal Transduction ATPases wit...
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WO/2024/024527A1 |
The present invention provides a mutant protease having improved cleaning performance with respect to protein dirtiness in a high-concentration detergent liquid. Provided is a mutant protease which comprises an amino acid sequence repres...
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WO/2024/025298A1 |
The present invention relates to a recombinant expression vector for secreting interleukin-12, and an attenuated Salmonella strain transformed therewith, and relates to: a recombinant expression vector comprising a flgM gene and an inter...
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WO/2024/025297A1 |
The present invention relates to a recombinant expression vector for secretion of interleukin-21, and an attenuated Salmonella strain transformed by means of same, and provides: a recombinant expression vector comprising the flgM gene an...
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WO/2024/024892A1 |
The present invention addresses the problem of providing a composition for cryopreservation that reduces cell damage due to cryopreservation and a cryopreservation method that reduces cell damage due to cryopreservation. A composition fo...
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WO/2024/020504A2 |
A system and method for growing microalgae capable of mixotrophic metabolism, preferably Chlorella sp. Microalgae grown in the system using the method are able to survive and grow in dark refrigeration, which allows the algae to be store...
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WO/2024/019354A1 |
The present invention relates to: a gene construct that enables, in an anticancer strain which is targeted to tumor sites and able to stimulate immune activity, the expression and secretion of a streptavidin (Stv)-fusion protein having t...
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WO/2024/019512A2 |
The present invention relates to an anti-aging composition comprising a microorganism expressing Dbn1, as an active ingredient and an anti-aging cosmetic composition using same. In the present invention, as research into the relationship...
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WO/2024/018033A1 |
The invention relates to a pharmaceutical composition capable of protecting a patient from disease caused by a pathogenic strain of a bacterium, that displays a wild type surface antigen. It comprises a probiotic component comprising a l...
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WO/2024/020533A1 |
The present disclosure features methods for treatment or prevention of actinomycetia (e.g., corynebacteriales) infections, e.g., caused by mycobacterial cells, residing within a host cell (e.g., a mammalian cell, e.g., immune cell, e.g.,...
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WO/2024/020252A1 |
Described herein are Schizosaccharomyces pombe yeast strains genetically engineered to produce lactic acid, wherein the best performing strains have two copies of a heterologous lactate dehydrogenase gene codon optimized for expression i...
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WO/2024/018105A1 |
The present invention relates to a method comprising the addition of a broad-spectrum preservative agent to a corn steep liquor, subsequent homogenization to resuspend all solids and mix the preservative appropriately. Then a thickening ...
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WO/2024/020436A1 |
The invention provides methods and compositions for modulating the immune system of an individual. The methods provided herein entail administering a composition comprising a killed or inactivated Mycobacterium or antigenic fragments der...
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WO/2024/017105A1 |
The present invention provides a transcription factor for improving the yield of echinocandin compounds. The overexpression of a transcription factor in a starting strain can improve the yield of echinocandin compounds. Further provided ...
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WO/2024/020364A1 |
Methods and systems to control continuous gas fermentation platforms for improved conversion of gas substrates into products is developed and particularly relates to a control process and system to control feedstock gases and maximize th...
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WO/2024/019215A1 |
The present invention relates to a Corynebacterium sp. microbe with enhanced L-arginine or L-citrulline production capability and a method for producing L-arginine or L-citrulline by using same. The Corynebacterium sp. variant can improv...
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WO/2024/016740A1 |
Provided is a biosynthesis-based preparation method for a structural material of the human body. A polypeptide of the present application contains the structure of a C-terminal region of (repeating unit)n or (repeating unit)n-; the repea...
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WO/2024/017398A1 |
Provided are a new type of efficient flocculation denitrifying bacteria and the use thereof. Thauera sp. JM12B12 is separated and screened from water in a Penaeus vannamei culture pond, and was preserved in Guangdong Microbial Culture Co...
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WO/2024/017956A2 |
Provided are cells that are resistant to mobile genetic elements or horizontal gene transfer, and methods for obtaining said cells. Also provided are methods for preventing the horizontal transfer of genetic information between a mobile ...
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WO/2024/018003A1 |
EVs are being recognized as vectors for drug delivery. In particular, EV loading with targeting and therapeutic agents brings along an interesting opportunity to translate EVs into a bio-mimetic selective delivery system. Indeed, EVs con...
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WO/2024/019355A1 |
The present invention relates to a gene construct characterized by encoding a fusion protein of flgM and strep-tag, wherein an anti-sigma factor flgM gene and a strep-tag-encoding gene are linked whereby the strep-tag can be expressed on...
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WO/2024/019516A1 |
The present invention relates to a method for cultivating microalgae, and the method for cultivating microalgae according to the present invention comprises: a step (S100) of injecting a KOH aqueous solution into a reaction vessel and su...
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WO/2024/019378A1 |
The present invention relates to a recombinant expression vector for conantokin-G secretion and an attenuated Salmonella strain transformed therewith, and provides: an attenuated Salmonella strain transformed with a recombinant expressio...
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WO/2024/020466A1 |
The disclosure relates to methods and compositions that provide for bacterial populations with increased potential for engraftment into the gut of mammalian systems. Accordingly, aspects of the disclosure relate to a bacterial cell or po...
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WO/2024/018036A1 |
The present invention relates to a platform based on unicellular algae, grown in a controlled environment, which serve as a biofactory for the production of biologically active metabolites.
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WO/2024/020197A1 |
The present disclosure provides pharmaceutical compositions comprising a microorganism capable of expressing one or more enzymes that convert salicin to saligenin, and salicin, or a pharmaceutically acceptable salt thereof. The present d...
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WO/2024/018434A1 |
The present disclosure relates to a Bacillus velezensis strain, and a composition for plant protection comprising an effective amount of said Bacillus velezensis. The use of the disclosed Bacillus velezensis strain or composition as a bi...
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WO/2024/019377A1 |
The present invention relates to a recombinant expression vector for melittin secretion and an attenuated Salmonella strain transformed therewith, and provides an attenuated Salmonella strain transformed with a recombinant expression vec...
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