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WO/2020/163935A1 |
The present invention provides biochemical pathways, glyoxylate producing recombinant microorganisms, and methods for the production and yield improvement of glycolic acid and/or glycine via a reverse glyoxylate shunt. The reverse glyoxy...
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WO/2020/155690A1 |
Provided is a system for efficiently catalyzing an aliphatic dinitrile hydration reaction using a new nitrile hydratase. Provided is the brand-new use of nitrile hydratase from Rhodococcus erythropolis CCM2595 in the catalysis of aliphat...
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WO/2020/152104A2 |
The invention is directed to methods for the production of 4-cyano benzoic acid or salts thereof from terephthalonitrile using nitrilase as catalyst and compositions comprising 4-cyano benzoic acid.
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WO/2020/150125A1 |
The present invention provides engineered transaminase polypeptides and compositions thereof, as well as polynucleotides encoding the engineered transaminase polypeptides. Methods for producing transaminase enzymes are also provided. In ...
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WO/2020/147031A1 |
Disclosed are a nitrile hydratase mutant, a genetically engineered bacterium containing the mutant, and the use thereof, falling within the technical field of enzyme engineering. According to the present invention, glycine at position 47...
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WO/2020/146587A1 |
Compositions for improving the bioavailability of methionine. In general, the compositions comprise a source of methionine and essential oil(s). More specifically, the compositions comprise a source of methionine and a plurality of coate...
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WO/2020/144371A1 |
The present invention relates to a recombinant microbial host cell comprising an operative biosynthetic metabolic pathway capable of producing one or more compounds selected from the group consisting of L-dopa, dopamine, (S)-Norcoclaurin...
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WO/2020/140388A1 |
A glutamic acid fermentation process, comprising the following steps: introducing Corynebacterium glutamicum into a fermentation tank filled with a clean fermentation medium for fermentation culture, performing ultrasonic treatment, and ...
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WO/2020/136236A1 |
The invention relates to a method and a device device for converting at least one reactant(5) into a reaction product and separating the at least one reactant from the reaction product, wherein the device comprises a vessel (10) with a v...
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WO/2020/135000A1 |
Disclosed is a preparation method for 3-phenyl-L-serine or derivatives thereof, comprising the following steps: a. obtaining 3-phenyl-L-serine or derivatives thereof on the basis of the reaction formula represented by Formula I, wherein ...
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WO/2020/138178A1 |
The present invention provides a method for producing a basic L-amino acid such as, for example, L-ornithine L-citrulline, L-arginine, L-histidine, and L-lysine by fermentation using a bacterium belonging to the family Enterobacteriaceae...
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WO/2020/133989A1 |
Disclosed are an amino acid dehydrogenase mutant and the use thereof in the synthesis of L-glufosinate. The amino acid dehydrogenase mutant is obtained by performing a single mutation or multiple mutations on amino acids at positions 95,...
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WO/2020/134689A1 |
A hericium erinaceus HT-3 with a preservation number of CCTCC No: M 2018567 and a screening method thereof, the screening method comprising steps such as obtaining a purified strain containing a hericium erinaceus tissue block; performin...
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WO/2020/134687A1 |
A method for preparing ergothioneine by biosynthesis. The method comprises the following steps: 1) strain inoculating, on slant, mycelia of Hericium erinaceus into a liquid seed medium for cultivation, so as to obtain a seed liquid; 2) i...
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WO/2020/138919A1 |
The present application relates to: an ornithine decarboxylase or a protein variant thereof; a polynucleotide encoding same; a microorganism containing same; and a method for producing putrescine by using same. The present invention achi...
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WO/2020/138815A1 |
The present invention pertains to: an L-amino acid-producing E. coli variant strain or Corynebacterium glutamicum variant strain having an enhanced ability to produce L-amino acids; and a method for producing L-amino acids using same. Th...
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WO/2020/138543A1 |
The present invention relates to a generation method for an ornithine decarboxylase mutant strain, characteristics of the mutant strain, a gene encoding the ornithine decarboxylase mutant strain, and a method for producing putrescine usi...
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WO/2020/133990A1 |
The present invention discloses a glufosinate dehydrogenase mutant and an application thereof in synthesizing L-glufosinate, the method using 2-carbonyl-4-(hydroxy-methyl-phosphoryl) butyric acid or a salt thereof as a substrate; in the ...
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WO/2020/133126A1 |
Disclosed is a method for preparing phosphatidylserine by ultrasonic assisted enzymolysis, comprising the following steps: adding 100-130 parts of a phospholipid to a mixture containing 150-200 parts of L-serine, 10-20 parts of anhydrous...
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WO/2020/130236A1 |
The present application pertains to a modified homoserine dehydrogenase, and a method for producing homoserine or a homoserine-derived L-amino acid using same.
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WO/2020/128434A1 |
Disclosed herein is a method of reducing an aromatic nitro compound. In some embodiments the method comprises the step of (i) contacting an aromatic nitro compound with a catalyst, wherein, the catalyst comprises: (a) disproportionation ...
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WO/2020/126484A1 |
The present invention relates to a process for biocatalytic amidation of non-protected amino acids comprising the step of contacting a non-protected amino acid with an ammonia source in the presence of an organic solvent and an enzyme.
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WO/2020/131574A1 |
A method for reducing a substrate selected from 2-methyl-5-nitropyridine and methyl 4-(2-fluoro-3-nitrobenzyl)piperazine-1-carboxylate is provided catalysed by a nitroreductase and a disproportionation agent.
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WO/2020/130384A1 |
The present invention relates to a method of producing beta or gamma amino acids using a glutamic acid regeneration reaction. The present invention can induce the production of high concentrations of beta and gamma amino acids by using g...
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WO/2020/120420A1 |
The present invention relates to an enzyme-catalyzed enantioselective method for preparing primary amines from the corresponding imines by using imine reductase enzymes.
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WO/2020/122505A1 |
The present invention relates to a mutant strain having enhanced L-glutamic acid producing ability, and an L-glutamic acid preparation method using same. A mutant strain according to one specific example of the present invention has redu...
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WO/2020/119280A1 |
The present invention relates to the technical field of bioengineering and food, and relates to a method for enzymatic resolution of a chiral substance, comprising the following steps: (1) preparing an enzyme solution having a lipase con...
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WO/2020/113289A1 |
Provided herein is a formulation that contains non-animal-derived hydroxyproline, and one or more of a further amino acid, a sweetening agent, a colouring agent, a flavouring agent, a vitamin, a mineral, a natural extract and/or a pharma...
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WO/2020/113226A1 |
Methods and processes for producing aerobic digestion products, such as organic acids, from a low-rank coal substrate are provided. Also provided are multistage bioreactor systems for carrying out the described methods and processes. In ...
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WO/2020/107780A1 |
Disclosed is a method for preparing (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid by means of a chemoenzymatic method, comprising: using a racemic 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid as a substrate, stereoselectively ...
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WO/2020/109367A1 |
The present invention essentially relates to a method for the fermentative production of L-lysine using an L-lysine excreting bacterium of the species Corynebacterium glutamicum having a completely or partly deleted whiB4 gene.
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WO/2020/111437A1 |
The present application relates to a CAMP receptor protein mutant, a microorganism comprising same, and a method for preparing L-amino acid by using same.
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WO/2020/112497A1 |
The present disclosure describes the engineering of microbial cells for fermentative production of 1,5-diaminopentane and provides novel engineered microbial cells and cultures, as well as related 1,5-diaminopentane production methods.
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WO/2020/111436A1 |
The present application pertains to a cAMP receptor protein mutant, a microorganism containing same, and an L-amino acid production method using same.
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WO/2020/111438A1 |
The present application pertains to a cAMP receptor protein mutant, a microorganism containing same, and an L-amino acid production method using same.
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WO/2020/099225A1 |
The invention relates to a culture medium, preferably a cell culture medium, comprising at least one keto acid selected from keto leucine, keto valine, keto isoleucine and keto phenylalanine and/or a salt of these keto acids. The inventi...
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WO/2020/090016A1 |
A method for producing an α-keto acid, said method comprising a step of culturing a microorganism, which contains a gene encoding an enzyme catalyzing an aldol reaction between pyruvic acid and a carbonyl compound, in the presence of a ...
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WO/2020/085556A1 |
The present invention relates to a recombinant Corynebacterium glutamicum strain wherein the lysE locus of Corynebacterium glutamicum PKC is transformed with plasmid pK19-mobsacB-lysEF/B, and to a method for producing cadaverine comprisi...
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WO/2020/079152A1 |
Process for producing aqueous polyacrylamide concentrates by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel, comminuting said aqueous polyacrylamide gel and mixing it with ...
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WO/2020/079124A1 |
Process for producing aqueous polyacrylamide compositions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel, comminuting said aqueous polyacrylamide gel and mixing it with ...
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WO/2020/079119A1 |
Method of providing aqueous polyacrylamide concentrates, wherein the process comprises preparing the concentrates at a location A by radically polymerizing an aqueous monomer solution comprising at least water and 1% to 14.9 % by weight ...
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WO/2020/079120A1 |
The present invention relates to a process for preparing ammonium (meth-) acrylate, aqueous ammonium (meth-) acrylate solutions obtainable by such process, and (meth-) acrylic acid homopolymers or copolymers obtainable by polymerizing su...
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WO/2020/070699A1 |
The present invention relates to preparation of key drug intermediate, L-2-amino butyric acid (L-2-ABA) by a method of cell free system and biotransformation using genetically engineered strains from easily available economic substrates ...
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WO/2020/071538A1 |
The present invention provides a method for producing a target substance, the biosynthetic pathway of which is ATP-dependent, such as, for example, amino acids, nucleosides, nucleotides, isoprenoids, and peptides, by fermentation of a ba...
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WO/2020/067618A1 |
The present application relates to an L-amino acid-producing microorganism exhibiting reinforced α-glucosidase activity, and an L-amino acid production method using same. The L-amino acid-producing Corynebacterium sp. microorganism, acc...
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WO/2020/062961A1 |
An L-aspartic acid α-decarboxylase mutant and an application thereof; the mutant is obtained by mutating lysine at position 221 of L-aspartic acid α-decarboxylase into arginine and by mutating glycine at position 369 into alanine; the ...
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WO/2020/064776A1 |
The invention relates to the use of a composition comprising a rod-shaped, aerobic, Gram-positive microorganism for the degradation of liquid polyether-based polyurethane, and to the composition derived from the degradation of said polye...
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WO/2020/067487A1 |
The present invention provides a method for producing L-methionine by fermentation using a bacterium which has been modified to overexpress a 1st gene and a 2nd gene, such as genes having the nucleotide sequences shown in SEQ ID NOs: 1 a...
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WO/2020/057476A1 |
Provided is an application of trehalase in fermentative production. The trehalase has amino acid sequences shown in SEQ ID NO.6, SEQ ID NO.7, and SEQ ID NO.8. Provided are methods for producing and applying trehalase, particularly being ...
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WO/2020/060970A1 |
The present disclosure generally relates to methods for the recovery of amines from aqueous mixtures. In particular, the disclosure relates to methods for separating amines from amine-containing aqueous mixtures by adjusting the pH of th...
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