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WO/2003/085377A2 |
This invention relates to newly identified human pancortin polypeptides, the interaction of the pancortin polypeptides with a Pablo polypeptide, the use of such polypeptides, as well as the production of such polypeptides. The invention ...
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WO/2003/066875A1 |
The invention relates to methods of (i) obtaining astaxanthin-overexpressing strains of X. dendrorhous and (ii) using said strains under improved fermentation conditions. The methods of selecting the strains used are based on: (i) resist...
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WO2002026933A9 |
The invention provides methods and materials related to the production of isoprenoids. Specifically, the invention provides isolated nucleic acids, substantially pure polypeptides, host cells, and methods and materials for producing vari...
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WO/2003/066866A2 |
A method is described for the cultivation of transgenic plants for lycopene cyclase characterized by temperature conditions ranging from 10 °C to 25 °C and the presence of continuous light. The method allows the content of total carote...
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WO/2003/064673A1 |
The invention relates to a method of producing $g(b)-carotene by means of mixed culture fermentation using (+) and (-) strains of Blakeslea trispora. The inventive method consists in fermenting selected strains of Blakeslea trispora unde...
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WO/2003/056028A1 |
The invention relates to a method of fermenting selected strains of B. Trispora which can be used to achieve lycopene production levels greater than current levels. The isolation, purification and formulation methods can be applied to an...
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WO2002079395A9 |
Membranous bacteria that produce astaxanthin and other carotenoids are described, as well as isolated nucleic acids and expression vectors that can be used for producing carotenoids in microorganisms.
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WO/2003/044205A1 |
Genes have been isolated from Rhodococcus and Deinococcus which encode a specific lycopene β-cyclase capable of converting acyclic carotenoids with at least one &psgr -end group to the corresponding asymmetric carotenoid containing a si...
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WO/2003/038064A2 |
The invention relates to Blakeslea trispora (B. trispora) strains producing at least 0.3 g/l lycopene, when co-cultivated for at least three days with a suitable strain of Blakeslea trispora of the opposite mating type in a suitable medi...
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WO/2003/033683A1 |
It is intended to provide a process for conveniently and efficiently producing a large amount of astaxanthin and canthaxanthin from a material which can be easily obtained. A microorganism Thraustochytrium sp. CHN−3 (FERM P−18556) ca...
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WO/2003/027267A1 |
This invention discloses a cyclic process for the production of astaxanthin rich biomass by cultivating Haematococcus algae. Modified nutrient medium containing 4 nitrogen sources is used for culturing the algae. Green motile cells produ...
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WO/2003/027293A1 |
The invention relates to biosynthetic genes of Blakeslea trispora $g(b)-carotene that code for lycopene cyclase/phytoene synthase (carRP) and phytoene dehydrogenase (carB). The carRP gene, which is characterised by DNA sequence SEQ ID NO...
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WO/2003/012056A2 |
A ketolase gene has been isolated from Rhodococcus erythropolis AN12 strain encoding a carotenoid modification enzyme of the carotenoid biosynthetic pathway. The gene and gene product are the first isolated from a Rhodococcus strain. Six...
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WO/2002/099095A2 |
Isolated polynucleotides encoding polypeptides having the activity of enzymes in the mevalonate pathway, e.g. hydroxymethylglutaryl-CoA reductase, isopetenyl diphosphate isomerase, hydroxymethylglutaryl-CoA synthase, mevolante kinase, ph...
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WO/2002/094982A2 |
A method of increasing a fraction of free carotenoids in a source of carotenoids in which at least some of the carotenoids are fatty acid esterified carotenoids is disclosed. The method is effected by contacting the source of carotenoids...
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WO/2002/086094A2 |
Genes have been isolated from Rhodococcus erythropolis AN12 strain encoding the isoprenoid biosynthetic pathway. The genes and gene products are the first isolated from a Rhodococcus strain. The genes and gene products of the present inv...
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WO2001022833A9 |
Pigment-containing materials to be added to feeds which comprise microbial culture precipitate containing carotenoid compounds at a high concentration. Because of being resistant to oxygen, light, etc., these materials can be stored in a...
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WO/2002/059341A1 |
A method of purifying crude xanthophylls characterized by comprising treating the crude xanthophylls, which are obtained by extracting algae with a solvent, with a lipase in the presence of water under acidic conditions without controlli...
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WO/2002/053530A1 |
The invention concerns a method for concentrating and stabilising carotene from vegetables or fruits, whereby in particular the fruits and vegetables are ground. The invention is characterised in that it consists in: blanching the result...
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WO2001042455A9 |
The present invention relates to engineering new biosynthetic pathways into microorganisms, in particular biosynthetic carotenoid pathways. New and improved catalytic functions of metabolic pathways are created by, for example, site-spec...
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WO/2002/041833A2 |
The invention provides materials and methods that can be used to make carotenoids having greater than 40 carbon atoms (C$m(g)40). The invention also provides isolated nucleic acid molecules that encode polypeptides that allow C40 caroten...
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WO/2002/038791A1 |
The inventive method for producing a lycopene-containing biomass consists in a separate growth of the Blakeslea trispora mycelial mushroom having a race 8A (+) and 8A (-). The races Blakeslea trispora 3C (+) and 3C (-), or 185A (+) and 1...
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WO/2002/020728A2 |
A high growth methanotrophic bacterial strain capable of growth on a C1 carbon substrate has been isolated and characterized. The strain has the unique ability to utilize both methane and methanol as a sole carbon source and has been dem...
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WO/2002/020815A2 |
A methanotrophic bacterium has been genetically engineered to produce cyclic terpenoids from geranyl pyrophosphate.
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WO/2002/020733A2 |
Genes have been isolated from Methylomonas 16a sp. encoding the isoprenoid biosynthetic pathway. The genes and gene products are the first isolated from a Methylomonas strain that is capable of utilizing single carbon (C1) substrates as ...
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WO/2002/018617A2 |
A method for the production of carotenoid compounds is disclosed. The method relies on the use of microorganisms which metabolize single carbon substrates for the production of carotenoid compounds in high yields.
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WO/2002/016583A2 |
The present invention relates generally to methods and techniques for the expression of metabolic pathways, novel gene fusion constructs encoding multi-functional enzymatic domains, and related hybrid proteins.
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WO/2002/014522A1 |
Provided are polynucleotides encoding Pyruvate:NADP+ oxidoreductases (PNO) as well as methods for obtaining the same. Furthermore, vectors comprising said polynucleotides are described, wherein the polynucleotides are operatively linked ...
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WO/2002/010429A1 |
The invention relates to a novel method for the production of $g(b)-carotene from submerged cultures of mucoral fungi such as Blakeslea, Choanephora or Phycomyces by adding lectin to the culture medium and performing pH control once ferm...
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WO/2001/083414A1 |
A process for the conversion of (3R,3'R,6'R)-lutein to 3'-epilutein, a carotenoid precursor for industrial production of naturally occurring (3R,3'R)-zeaxanthin, is disclosed.
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WO/2001/083437A1 |
The present invention relates to a process for extracting astaxanthin pigment from the yeast cells of Phaffia rhodozyma comprising the steps of i) cultivating the yeast, ii) treating yeast culture suspension with microwave to destroy the...
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WO/2001/081301A2 |
The present invention provides a method for preparing astaxanthin from zeaxanthin. Specifically, the present invention provides a method for said conversion using a halogenating agent with the salt of chloric or bromic acid in an inert s...
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WO/2001/066703A1 |
A lycopene $g(e) cyclase from spinach is described, as is production of lutein in microorganisms by expression of the lycopene $g(e) cyclase.
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WO/2001/062894A2 |
Disclosed is a method for producing an effective amount of one or more carotenoid, xanthophyll, or apo-carotenoid pigments from a microorganism from the Order Thraustochytriales.Suitable microorganisms put forth are of the genus Thrausto...
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WO/2001/060977A1 |
Health foods containing a metabolite obtained by culturing mixed cells of a purple photosynthetic bacterium (for example, Rhodopseudomonas capsulata FERMBP-7434 strain) with a lactic acid bacterium (for example, lactobacillus). These hea...
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WO/2001/055100A1 |
The present invention relates to a crystalline carotenoid compound, such as $g(b)-carotene, with a purity of at least 95 % and with substantially no solvent enclosed in the crystal lattice. The present invention further describes a proce...
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WO/2001/053512A1 |
The present invention provides a method for extracting lipids from microorganisms without using a nonpolar organic solvent as an extraction solvent. In particular, the present invention provides a method for extracting lipids from microo...
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WO/2001/051648A2 |
A method of producing a carotenoid in solid form includes culturing a strain of Chlorophyta algae cells in a minimal inorganic medium and separating the algae comprising a solid form of carotenoid. In one embodiment of the invention, the...
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WO/2001/048163A2 |
The present invention provides means and methods of transforming bacteria, fungi including yeast, animal and plant cells, seeds, tissues and whole plants in order to yield transformants capable of expressing novel $g(b)-carotene dioxygen...
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WO/2001/048162A2 |
The present invention provides means and methods of transforming bacteria, fungi including yeast, animal and plant cells, seeds, tissues and whole plants in order to yield transformants capable of expressing a $g(b)-carotene (15, 15') di...
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WO/2001/012832A1 |
The present invention relates to a new process for producing carotenoids, specially lycopen, from natural biosynthetic sources in general and, in particular from immersed cultures of mucoral fungi such as Blakeslea, Choanephora or Phycom...
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WO/2001/011055A1 |
The present invention relates to enzymatic activity involved in isoprenoid biosynthesis as well as to inhibitors, notably herbicides, for enzymes in the biosynthesis of isoprenoids. More specifically, the present invention relates to scr...
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WO/2001/007567A1 |
The invention features a method of producing heterologous molecules in cells under the regulatory control of a metabolite and metabolic flux. The method can enhance the synthesis of heterologous polypeptides and metabolites.
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WO/2000/077234A2 |
The invention relates to a novel method for obtaining carotenoids, especially as Blakeslea. Disclosed is a fermentation method enabling increased lycopen production based on trisporic acid addition. The process is carried out using wild ...
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WO/2000/061764A1 |
The invention relates to proteins with an enzymatic activity for converting $g(b)-carotene into zeaxanthin or canthaxanthin into astaxanthin, to nucleic acids that code for these proteins, to nucleic acid constructs containing these nucl...
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WO/2000/024369A1 |
The invention relates to sunscreen compositions for humans including naturally occurring sunscreen agents from plants, algae, cyanobacteria, fungi and bacteria that protect against exposure to solar radiation. The active sunscreen agents...
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WO/2000/023605A1 |
The invention concerns a cDNA (complementary deoxyribonucleic acid) sequence represented by SEQ ID NO: 1, transcribing a mRNA (messenger deoxyribonucleic acid), itself coding for the TOCB (terminal oxydase associated with carotenoid bios...
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WO1999063055A9 |
Nucleic acid sequences encoding epsilon -cyclase, isopentenyl pyrophosphate isomerase and beta -carotene hydroxylase as well as vectors containing the same and hosts transformed with the vectors. Methods for controlling the ratio of vari...
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WO/2000/001650A1 |
The invention provides a method of producing $g(a)-tocopherol and $g(a)-tocopheryl esters and a method of producing vitamin A or $g(b)-carotene. The methods comprise using a biological system to produce farnesol or geranylgeraniol. Then,...
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WO/1999/061399A1 |
The present invention relates to the DNA sequence for eukaryotic genes encoding $g(e) cyclase isolated from romaine lettuce as well as vectors containing the same and hosts transformed with said vectors. The present invention provides me...
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