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WO/2024/017393A1 |
A primer pair for detecting bovine genomic DNA, a detection reagent or kit containing the primer pair, and a method for detecting bovine genomic DNA by using the primer pair, the primer pair specifically binding to the sequence represent...
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WO/2024/016730A1 |
A method for reducing the off-target rate of a Cas protein (such as CRISPR-Cas12a) specifically cleaving a target nucleic acid by changing the concentration of ions or ions. Specifically, provided is a reaction system comprising a soluti...
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WO/2024/020527A1 |
The present invention provides methods for using waste effluent biofluids in cell culture assays as all or part of the cell culture microenvironment. Methods of the invention contemplate that biofluids typically regarded as waste may be ...
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WO/2024/020395A2 |
Provided herein are compositions, kits, and methods for collection, integration and analysis of various facets of information from tissues at the cellular or subcellular level. Information includes spatial mapping from nucleic acid barco...
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WO/2024/020373A2 |
Various compositions and diagnostic devices for the detection of nucleic acids are provided. Also provided are systems comprising the same, and methods of using the same. In some embodiments, compositions and devices comprise or are conf...
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WO/2024/020364A1 |
Methods and systems to control continuous gas fermentation platforms for improved conversion of gas substrates into products is developed and particularly relates to a control process and system to control feedstock gases and maximize th...
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WO/2024/020412A2 |
Methods and systems for rapid preparation of a nucleic acid sample.
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WO/2024/018266A1 |
The present invention relates to a method for simultaneously detecting and identifying multiple species of mussels of the genus Mytilus and associated oligonucleotides/probes, including their first-generation hybrids and hybrids from oth...
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WO/2024/017263A1 |
Provided is a composition comprising an antibody linked with an oligonucleotide via a disulfide bond, wherein the oligonucleotide is specific for the antibody. Further provided is a kit comprising the same and the method for detecting on...
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WO/2024/019165A1 |
The present invention addresses the problem of providing a method and a kit for easily detecting a microorganism or a cell. Provided are a method for detecting a microorganism or a cell, and a kit for the method. The method comprises a...
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WO/2024/019492A1 |
The present invention relates to a COVID-19 infection model using lung organoids. Lung organoids infected with a respiratory virus, produced according to the present invention, are expected to be effectively used in preclinical or clinic...
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WO/2024/018097A1 |
The present invention relates to a diagnosis method for bladder cancer and a cancer staging method of the tumour that caused it. The method comprises measuring the expression levels of a miRNA group in a sample extracted from a patient. ...
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WO/2024/017613A1 |
The present invention relates to a composition which can be used as spike-in cocktail. Further, the present invention relates to a kit comprising the composition. Furthermore, the present invention relates to a method for examining a sam...
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WO/2024/020398A1 |
The present disclosure is directed to methods for measuring proteomes of single cells. In one aspect, methods comprise disposing cells on a surface, synthesizing hydrogel chambers around each of the cells, lysing the cells to release int...
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WO/2024/018079A1 |
The present invention proposes a method of determining the existence and/or degree of resistance of a microorganism to one or more antimicrobial agents.
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WO/2024/020124A1 |
The methods, compositions and kits described herein provide signal amplification approaches for the detection of target biomolecules that significantly increase the sensitivity of detection using target-binding ligand molecules. The meth...
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WO/2024/019657A1 |
This document describes a system and method for enumerating a concentration of microorganism in a liquid sample. The disclosed system has a filtration medium that has an inlet for receiving the liquid sample and an outlet for removing a ...
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WO/2024/016625A1 |
Provided in the present invention is a rapid next-generation sequencing method, which comprises the following steps: polymerization, involving: a detection complex is linked to a primer hybridized to a nucleic acid molecule to be detecte...
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WO/2023/240611A9 |
The present invention belongs to the field of gene sequencing, and particularly relates to a library construction and sequencing method for a single-stranded nucleic acid cyclic library. In the method, a sequencing primer binding sequenc...
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WO/2024/020166A1 |
Buffer compositions, such as two-part buffer compositions and buffer systems, methods, assays, kits and kits of parts comprising buffers, for rapid, non-hazardous and fully automated extraction of nucleic acids from various samples. The ...
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WO/2024/020325A1 |
The present disclosure provides devices, systems, and methods capable of optimizing in vivo electrochemical measurement of a molecule of interest, for example glucose. Disclosed aspects may include an interference zapping layer, to which...
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WO/2024/019326A1 |
The present disclosure relates to a method and a device for predicting a nucleic acid amount on the basis of a pathological image and proposing the optimal gene test. This method may comprise the steps of: receiving a pathological image ...
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WO/2024/019113A1 |
Provided, with respect to the production of inactivated whole influenza virus particle vaccines using the embryonated chicken egg method, is a method for reducing pyrogenic activity. With respect to the method for producing an inactiva...
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WO/2024/016944A1 |
Disclosed is a novel molecular target through which aspirin exerts a neuroprotective effect on cerebral apoplexy. Aspirin exerts a neuroprotective effect on a mouse model of cerebral apoplexy by means of acetylating calcium ion-calmoduli...
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WO/2024/017763A1 |
The present invention relates to a method for detecting a target nucleic acid in a sample using an optimized SMART method that comprises the use of at least one fluorogenic aptamer for the direct detection of the RNA transcripts. Prefera...
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WO/2024/018971A1 |
The purpose of the present invention is to accurately calculate the number of cells. A cell culture device 1 comprises a sensor 26 for measuring the lactic acid concentration in a medium. The sensor 26 measures the concentration of lacti...
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WO/2024/020573A1 |
The disclosure relates to improved sequencing reactions. Specifically, the disclosure provides methods which allow for the identification of regions of a DNA molecule that were synthesized during an end repair and/or A-tailing reaction. ...
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WO/2024/020414A1 |
Methods and systems for rapid preparation of a nucleic acid sample.
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WO/2024/020578A2 |
Systems and methods for determining an effect regulatory untranslated RNA elements are provided. A plurality of RNA untranslated region (UTR) sequences are designed, subject to a requirement that each UTR RNA sequence includes one or mor...
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WO/2024/016461A1 |
Provided in the present invention is a method for preparing a bispecific-probe-coupled capture magnetic bead, which method comprises: coupling a capture magnetic bead to a bispecific probe, wherein hypoxanthine is introduced into a posit...
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WO/2024/020410A1 |
Provided are systems and compositions for dual-end sequencing.
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WO/2024/019166A1 |
The present invention addresses the problem of providing a simple method and a simple kit both for detecting a microorganism or a cell in a solution. Provided are: a method for detecting a microorganism or a cell in a solution, the met...
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WO/2024/019556A1 |
The present invention relates to a composition, kit, and method for predicting the risk of progression of Alzheimer's disease by detecting the methylation level of the CpG region of a Keratin 32 (KRT32) gene promoter, and has the effect ...
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WO/2024/015621A1 |
A method for assessing a lupus nephritis disease state of a patient, the method comprising: analyzing a data set comprising or derived from gene expression measurement data of at least 2 genes or human orthologs thereof selected from the...
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WO/2024/014834A1 |
The present invention relates to a biomarker for the early diagnosis of Alzheimer's disease and a use thereof, and more particularly, the present invention relates to: a biomarker composition for the early diagnosis of Alzheimer's diseas...
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WO/2024/015624A1 |
Methods and devices for determining the hematocrit of blood samples.
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WO/2024/015766A1 |
Scalable stamping methods to replicate a template microarray are provided.
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WO/2024/015999A1 |
The present disclosure provides methods, systems, and compositions for the multiplexed detection and quantification of multiple analytes from a sample. Analytes may be nucleic acid analytes. Detection of analytes may comprise contacting ...
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WO/2024/015952A1 |
Current immuno-PCR methods are limited in the number or antigens that can be assayed, the ability to quantitate those antigens, and the ability to detect antigens across multiple samples in a single detection step. Provided herein are me...
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WO/2024/015879A1 |
The present disclosure relates to measuring gene expression of cells of a blood sample obtained from a mammalian subject suspected of having a tick-borne disease. In particular, the present disclosure provides tools for determining wheth...
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WO/2024/013271A1 |
The application, inter alia, provides a method for detecting a target nucleic acid, the method comprising the steps of (a) amplifying a target nucleic acid providing an amplified nucleic acid; (b) bringing the amplified nucleic acid in c...
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WO/2024/015843A1 |
Provided herein are quantitative assays to evaluate duplex unwinding efficiency or strand exchange efficiency during isothermal amplification.
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WO/2024/012467A1 |
A method for detecting nucleic acids by fluorescent PCR, combining primer-activated polymerization reaction and specific fluorescence-labeled probe, which detects the target nucleic acid with high selectivity and high specificity.
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WO/2024/015992A1 |
The present disclosure provides methods and compositions for detection of multiple nucleic acid target variations in a single optical channel in a digital assay. In some cases, three or more nucleic acid target variations may be detected...
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WO/2024/014536A1 |
The present invention relates to a compound represented by a general formula (1) or a salt or a solvate thereof. [In the formula, R1, R2, and R3 are as defined in the description.]
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WO/2024/012418A1 |
A chromatin three-dimensional conformation capture method, comprising: performing chromatin proximity ligation in situ, and performing spatial location information specific labelling on a proximity ligation product, such that chromatin t...
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WO/2024/015966A2 |
Novel AAV capsids and recombinant AAV vectors comprising the same are provided.
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WO/2024/014580A1 |
The present invention relates to a method for providing information for cancer diagnosis, the method comprising the steps of: isolating an exosome fraction from a biological sample isolated from an individual of interest; and measuring t...
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WO/2024/014502A1 |
The purpose of the present invention is to provide a novel antibody production method. Provided is a method for producing an antibody capable of binding to an extracellular vesicle, the method comprising: (1) a step for bringing an antib...
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WO/2024/015875A2 |
The present disclosure relates to compositions of matter, methods, and systems for analyzing polymeric macromolecules, including polymeric macromolecules such as peptides, polypeptides, and proteins.
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