Title:
【発明の名称】殺精子活性および抗ウイルス活性を示すAZT誘導体
Document Type and Number:
Japanese Patent JP2002507622
Kind Code:
A
Abstract:
Contraceptive activity as well as anti-viral protection can be provided by contraceptive compositions containing a pyrimidine-based nucleoside or nucleotide exhibiting spermicidal or sperm-immobilizing activity. In one example, the active ingredient contains a thymine ring (e.g. AZT) that has 5-halo, 6-alkoxy substitution. Additional improvements in anti-HIV activity for certain AZT derivatives are seen by providing the pentose ring of AZT with aryl phosphate substitution.
Inventors:
Dokraz, Osmond
Ukkun, Fatty, M.
Venkatacharam, cod card
Ukkun, Fatty, M.
Venkatacharam, cod card
Application Number:
JP2000537885A
Publication Date:
March 12, 2002
Filing Date:
March 23, 1999
Export Citation:
Assignee:
Parker Hughes Institute
International Classes:
A61K9/00; A61K31/7042; A61K31/7052; A61K31/7064; A61K31/7072; A61P15/00; A61P31/18; C07H19/06; C07H19/10; (IPC1-7): C07H19/06; A61K9/00; A61K31/7072; A61P15/00; C07H19/10
Attorney, Agent or Firm:
Hiroyuki Ikeuchi (3 outside)