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Title:
【発明の名称】置換アリール誘導体及び置換ヘテロアリール誘導体、それらの調製及び薬物としてのそれらの使用
Document Type and Number:
Japanese Patent JP2002532460
Kind Code:
A
Abstract:
Compounds that prolong thrombin time. Exemplary are:(a) rac-4-{3-[5-ethoxycarbonylmethyl-2-methyl-4-(2-methyl-pyrrolidinocarbonyl)-phenyl]-propargylamino}benzamidine,(b) rac-4-{3-[2,5-dimethyl-4-(2-methyl-pyrrolidinocarbonyl)-phenyl]-propargylamino}benzamidine, and(c) 4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine.

Inventors:
Prepke Henning
Kaufman Iliz
Howell norbert
Leeds Uwe
Naru Herbert
Stassen Yan Marie
Wienen Wolfgang
Application Number:
JP2000588121A
Publication Date:
October 02, 2002
Filing Date:
December 13, 1999
Export Citation:
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Assignee:
Boehringer Ingelheim Pharma Comandito Gezelshaft
International Classes:
C07D295/08; A61K31/15; A61K31/155; A61K31/167; A61K31/192; A61K31/216; A61K31/223; A61K31/343; A61K31/381; A61K31/397; A61K31/40; A61K31/403; A61K31/404; A61K31/407; A61K31/415; A61K31/4174; A61K31/4184; A61K31/42; A61K31/426; A61K31/44; A61K31/443; A61K31/4465; A61K31/454; A61K31/495; A61K31/496; A61K31/535; A61K31/5355; A61K31/5375; A61K31/5377; A61P7/02; A61P43/00; C07C257/18; C07D205/08; C07D207/06; C07D207/08; C07D207/09; C07D207/20; C07D207/335; C07D209/08; C07D211/32; C07D213/50; C07D231/12; C07D233/54; C07D233/60; C07D233/61; C07D233/64; C07D235/08; C07D235/14; C07D261/08; C07D277/24; C07D307/88; C07D333/22; C07D405/04; C07D487/04; C07D235/10; (IPC1-7): C07C257/18; A61K31/15; A61K31/155; A61K31/167; A61K31/192; A61K31/216; A61K31/223; A61K31/343; A61K31/381; A61K31/397; A61K31/40; A61K31/404; A61K31/407; A61K31/415; A61K31/4174; A61K31/42; A61K31/426; A61K31/44; A61K31/4465; A61K31/495; A61K31/535; A61P7/02; A61P43/00; C07D205/08; C07D207/06; C07D207/09; C07D207/20; C07D207/335; C07D209/08; C07D211/32; C07D231/12; C07D233/60; C07D233/61; C07D233/64; C07D235/08; C07D261/08; C07D277/24; C07D295/08; C07D307/88; C07D333/22; C07D405/04; C07D487/04
Attorney, Agent or Firm:
Minoru Nakamura (9 outside)