Title:
【発明の名称】ラテックス被膜を有する徐放性剤形単位及びその製造方法
Document Type and Number:
Japanese Patent JP2003503444
Kind Code:
A
Abstract:
Dosage form unit is provided to deliver one or more beneficial agents into a fluid, such as liquid enteral nutritional product. The dosage form unit includes a core containing at least one beneficial agent, preferably a marker dye, which is dispersible in the fluid. The core also contains a compatible binding agent to bind the beneficial agent together. Additional components of the core may include a plasticizer, a standard flow agent, a lubricant, additional tableting aids and at least one hydrophilic agent. A latex coating encases the core. The latex coating includes a mixture containing a substantially hydrophobic base material, preferably formed from an emulsion of cellulose acetate microspheres, which is capable of defining a matrix-type membrane, and at least one hydrophilic component being dispersible in the fluid. A dispersible beneficial agent is preferred as one of the hydrophilic components of the latex coating to allow immediate release of the beneficial agent therefrom. A method of making the dosage form unit also is provided.
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Inventors:
Mather, Terry Bee
Walton, Yosef Yi
Arnholt, Barbara Es
Evans, Montei El
Gakule, Lonita Kay
Hamilton, Daniel
Kroptinsky, Jiyoung Jei, Giunia
Murawski, Franca A
Tatsuker, Larry Gee
Walker, Serie A
Walshille, Michael Buoy
Ronda Yee
Walton, Yosef Yi
Arnholt, Barbara Es
Evans, Montei El
Gakule, Lonita Kay
Hamilton, Daniel
Kroptinsky, Jiyoung Jei, Giunia
Murawski, Franca A
Tatsuker, Larry Gee
Walker, Serie A
Walshille, Michael Buoy
Ronda Yee
Application Number:
JP2001507461A
Publication Date:
January 28, 2003
Filing Date:
June 28, 2000
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
A61K9/20; A61K9/28; A61K9/30; A61K9/34; A61K9/36; A61K47/38; (IPC1-7): A61K9/28; A61K47/38
Domestic Patent References:
| JPH03275618A | 1991-12-06 | |||
| JPH02229110A | 1990-09-11 |
Attorney, Agent or Firm:
Yoshio Kawaguchi (5 outside)